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ONTOLOGY REPORT - ANNOTATIONS


Term:NADH metabolic process
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Accession:GO:0006734 term browser browse the term
Definition:The chemical reactions and pathways involving reduced nicotinamide adenine dinucleotide (NADH), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.
Synonyms:exact_synonym: NADH metabolism;   reduced NAD metabolic process;   reduced NAD metabolism;   reduced nicotinamide adenine dinucleotide metabolic process;   reduced nicotinamide adenine dinucleotide metabolism



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NADH metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlst dihydrolipoamide S-succinyltransferase IDA RGD PMID:9405249 RGD:1359804 NCBI chr 6:104,758,511...104,783,296
Ensembl chr 6:104,758,631...104,783,296
JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 IDA RGD PMID:12351438 RGD:2303499 NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529
JBrowse link
G Gpd1l glycerol-3-phosphate dehydrogenase 1-like acts_upstream_of_or_within ISO (MGI:4943631|PMID:19745168) RGD PMID:19745168 MGI:4943631 NCBI chr 8:114,591,103...114,620,771
Ensembl chr 8:114,588,487...114,620,723
JBrowse link
G Gpd2 glycerol-3-phosphate dehydrogenase 2 IDA RGD PMID:12351438 RGD:2303499 NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901
JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha IDA RGD PMID:938457 RGD:2306828 NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084
JBrowse link
G Idh3b isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta IDA RGD PMID:938457 RGD:2306828 NCBI chr 3:117,481,845...117,486,909
Ensembl chr 3:117,481,845...117,486,982
JBrowse link
G Idh3g isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma IDA RGD PMID:938457 RGD:2306828 NCBI chr  X:151,515,244...151,524,175
Ensembl chr  X:151,515,247...151,524,171
JBrowse link
G Mdh1 malate dehydrogenase 1 involved_in IDA
ISO
IBA
(PMID:34547241)
PMID:21873635
RGD PMID:34547241 PMID:12351438 PMID:21873635 RGD:2303499, RGD:13792537 NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925
JBrowse link
G Mdh1b malate dehydrogenase 1B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:65,120,370...65,168,008
Ensembl chr 9:65,119,029...65,167,933
JBrowse link
G Mdh2 malate dehydrogenase 2 IDA RGD PMID:12351438 RGD:2303499 NCBI chr12:20,894,269...20,907,225
Ensembl chr12:20,894,262...20,907,271
JBrowse link
G Me1 malic enzyme 1 involved_in ISO
IEA
(PMID:34547241)
GO_REF:0000107
RGD
Ensembl
PMID:34547241 GO_REF:0000107 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
JBrowse link
G Nudt12 nudix hydrolase 12 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:98,741,627...98,755,039
Ensembl chr 9:98,742,360...98,755,039
JBrowse link
G Nudt13 nudix hydrolase 13 involved_in ISO (MGI:6368098|PMID:28755312) RGD PMID:28755312 MGI:6368098 NCBI chr15:4,001,787...4,022,404
Ensembl chr15:4,001,794...4,022,293
JBrowse link
G Nudt17 nudix hydrolase 17 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:184,241,468...184,243,960
Ensembl chr 2:184,241,468...184,243,960
JBrowse link
G Ogdh oxoglutarate dehydrogenase IDA RGD PMID:9712727 RGD:2306877 NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
JBrowse link
G Pc pyruvate carboxylase involved_in ISO
IEA
(PMID:34547241)
GO_REF:0000107
RGD
Ensembl
PMID:34547241 GO_REF:0000107 NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380
JBrowse link
G Vcp valosin-containing protein involved_in ISO (PMID:23498975) RGD PMID:23498975 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571
JBrowse link
canonical glycolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldoa aldolase, fructose-bisphosphate A involved_in ISO (MGI:5819300|PMID:28049690) RGD PMID:28049690 MGI:5819300 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
JBrowse link
G Eno1 enolase 1 involved_in ISO
IDA
(PMID:29775581), (PMID:3529090)
PMID:15041191
RGD PMID:3529090 PMID:29775581 PMID:15041191 RGD:2302788 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G Eno2 enolase 2 involved_in IDA PMID:15041191 CAFA PMID:15041191 RGD:2302788 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Eno3 enolase 3 involved_in ISO MGI:1196256 (MGI:5892183|PMID:27760309) RGD PMID:27760309 MGI:5892183 NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921
JBrowse link
G Foxk1 forkhead box K1 acts_upstream_of ISO (PMID:30700909) RGD PMID:30700909 NCBI chr12:12,110,119...12,175,089
Ensembl chr12:12,115,950...12,175,089
JBrowse link
G Foxk2 forkhead box K2 acts_upstream_of ISO (MGI:6281052|PMID:30700909) RGD PMID:30700909 MGI:6281052 NCBI chr10:106,542,643...106,592,569
Ensembl chr10:106,542,566...106,592,563
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase involved_in ISO (MGI:2651735|PMID:12581789)
(MGI:2651735|PMID:12581789), (MGI:6861792|PMID:10777777)
(MGI:2651735|PMID:12581789), (MGI:6106926|PMID:28918937), (MGI:6861792|PMID:10777777)
RGD PMID:10777777 PMID:12581789 PMID:28918937 MGI:2651735 MGI:6106926 MGI:6861792 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Hk1 hexokinase 1 involved_in ISO (MGI:6861806|PMID:4275392) RGD PMID:4275392 MGI:6861806 NCBI chr20:30,230,488...30,332,161
Ensembl chr20:30,230,486...30,332,131
JBrowse link
G Pfkl phosphofructokinase, liver type involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:10,664,285...10,686,324
Ensembl chr20:10,664,272...10,686,315
JBrowse link
G Pfkm phosphofructokinase, muscle involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000107
MGI:1196256 (MGI:5819300|PMID:28049690), (MGI:5892183|PMID:27760309), (MGI:6861806|PMID:4275392)
MGI:4356541 (MGI:4356361|PMID:19696889)
PMID:21873635
Ensembl
RGD
PMID:4275392 PMID:19696889 PMID:27760309 PMID:28049690 PMID:21873635 GO_REF:0000107 MGI:4356361 MGI:5819300 MGI:5892183 MGI:6861806, RGD:13792537 NCBI chr 7:129,221,679...129,259,192
Ensembl chr 7:129,221,653...129,259,192
JBrowse link
G Pfkp phosphofructokinase, platelet involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:63,729,743...63,794,021
Ensembl chr17:63,729,780...63,794,018
JBrowse link
G Pgam2 phosphoglycerate mutase 2 involved_in ISO (MGI:5543738|PMID:23951293) RGD PMID:23951293 MGI:5543738 NCBI chr14:80,681,796...80,683,907
Ensembl chr14:80,681,776...80,683,940
JBrowse link
G Pgk1 phosphoglycerate kinase 1 involved_in ISO MGI:3780541 (MGI:6857632|PMID:30174313) RGD PMID:30174313 MGI:6857632 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418
JBrowse link
G Pkm pyruvate kinase M1/2 involved_in ISO (MGI:5908042|PMID:28630053) RGD PMID:28630053 MGI:5908042 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
JBrowse link
G Tpi1 triosephosphate isomerase 1 involved_in ISO MGI:3780541 (MGI:6857632|PMID:30174313) RGD PMID:30174313 MGI:6857632 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
JBrowse link
glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldha lactate dehydrogenase A acts_upstream_of_or_within ISO MGI:2384559 (MGI:62497|PMID:8224816) RGD PMID:8224816 MGI:62497 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of ISO (MGI:4867601|PMID:20935145) RGD PMID:20935145 MGI:4867601 NCBI chr 4:159,927,138...159,946,094
Ensembl chr 4:159,927,139...159,946,029
JBrowse link
G Tp53 tumor protein p53 acts_upstream_of ISO (MGI:4867601|PMID:20935145) RGD PMID:20935145 MGI:4867601 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
glycerophosphate shuttle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpd1 glycerol-3-phosphate dehydrogenase 1 acts_upstream_of_or_within ISO MGI:3692960 (MGI:1927687|PMID:11147825) RGD PMID:11147825 MGI:1927687 NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529
JBrowse link
NADH oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldob aldolase, fructose-bisphosphate B involved_in ISO
IEA
(PMID:17576770)
GO_REF:0000107
RGD
Ensembl
PMID:17576770 GO_REF:0000107 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116
JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 acts_upstream_of_or_within
involved_in
IDA
ISO
IBA
MGI:3692960 (MGI:1927687|PMID:11147825)
PMID:21873635
RGD PMID:11147825 PMID:9550546 PMID:21873635 MGI:1927687, RGD:1641824, RGD:13792537 NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529
JBrowse link
G Gpd1l glycerol-3-phosphate dehydrogenase 1-like NOT|involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:114,591,103...114,620,771
Ensembl chr 8:114,588,487...114,620,723
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 IDA RGD PMID:29389585 RGD:25823193 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) IDA
IMP
RGD PMID:19635791 PMID:19635791 RGD:7242950, RGD:7242950 NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283
JBrowse link
negative regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc25a12 solute carrier family 25 member 12 IMP RGD PMID:19764902 RGD:13628741 NCBI chr 3:56,098,080...56,192,188
Ensembl chr 3:56,097,269...56,192,100
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within ISO (MGI:4867601|PMID:20935145) RGD PMID:20935145 MGI:4867601 NCBI chr 4:159,927,138...159,946,094
Ensembl chr 4:159,927,139...159,946,029
JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO (MGI:4867601|PMID:20935145) RGD PMID:20935145 MGI:4867601 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
positive regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in ISO (MGI:3759354|PMID:17828264) RGD PMID:17828264 MGI:3759354 NCBI chr 1:202,159,081...202,175,012
Ensembl chr 1:202,159,082...202,175,012
JBrowse link
G Mir210 microRNA 210 involved_in ISO (PMID:20436681) RGD PMID:20436681 NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18877
    metabolic process 11591
      NADH metabolic process 41
        NADH oxidation + 5
        NADH regeneration + 15
        glucose catabolic process to lactate via pyruvate + 6
        sulphoglycolysis 0
paths to the root