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ONTOLOGY REPORT - ANNOTATIONS

Term:NADH metabolic process
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Accession:GO:0006734 term browser browse the term
Definition:The chemical reactions and pathways involving reduced nicotinamide adenine dinucleotide (NADH), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.
Synonyms:exact_synonym: NADH metabolism;   reduced NAD metabolic process;   reduced NAD metabolism;   reduced nicotinamide adenine dinucleotide metabolic process;   reduced nicotinamide adenine dinucleotide metabolism


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NADH metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLST dihydrolipoamide S-succinyltransferase ISO RGD PMID:9405249 RGD:1359804 NCBI chr 7:98,091,161...98,111,267
Ensembl chr 7:98,091,123...98,111,572 		JBrowse link
G GPD1 glycerol-3-phosphate dehydrogenase 1 ISO RGD PMID:12351438 RGD:2303499 NCBI chr 5:16,008,179...16,021,676
Ensembl chr 5:16,007,448...16,017,825 		JBrowse link
G GPD1L glycerol-3-phosphate dehydrogenase 1 like acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:4943631|PMID:19745168) MGI
Ensembl
Ensembl		 PMID:19745168 GO_REF:0000107 MGI:4943631 NCBI chr13:18,126,471...18,176,669
Ensembl chr13:18,126,623...18,176,668 		JBrowse link
G GPD2 glycerol-3-phosphate dehydrogenase 2 ISO RGD PMID:12351438 RGD:2303499 NCBI chr15:63,592,723...63,728,636
Ensembl chr15:63,592,698...63,728,634 		JBrowse link
G IDH3A isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha ISO RGD PMID:938457 RGD:2306828 NCBI chr 7:47,759,436...47,778,948
Ensembl chr 7:47,759,431...47,778,956 		JBrowse link
G IDH3B isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta ISO RGD PMID:938457 RGD:2306828 NCBI chr17:32,955,061...32,960,110
Ensembl chr17:32,955,101...32,960,106 		JBrowse link
G IDH3G isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma ISO RGD PMID:938457 RGD:2306828 NCBI chr  X:124,528,643...124,537,570
Ensembl chr  X:124,528,644...124,538,298 		JBrowse link
G MDH1 malate dehydrogenase 1 involved_in ISO
IEA
IBA		 (PMID:21873635) RGD
Ensembl
GO_Central
GO_Central		 PMID:12351438 PMID:21873635 GO_REF:0000107 RGD:2303499 NCBI chr 3:78,247,229...78,263,085
Ensembl chr 3:78,244,999...78,440,488 		JBrowse link
G MDH1B malate dehydrogenase 1B involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr15:109,989,095...110,021,237
Ensembl chr15:109,989,062...110,021,195 		JBrowse link
G MDH2 malate dehydrogenase 2 ISO RGD PMID:12351438 RGD:2303499 NCBI chr 3:10,120,121...10,132,705
Ensembl chr 3:10,120,084...10,132,830 		JBrowse link
G ME1 malic enzyme 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:82,799,878...82,989,895
Ensembl chr 1:82,794,964...82,991,104 		JBrowse link
G NUDT12 nudix hydrolase 12 involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr 2:109,044,946...109,059,721
Ensembl chr 2:109,044,948...109,059,624 		JBrowse link
G NUDT13 nudix hydrolase 13 involved_in ISO (MGI:6368098|PMID:28755312) UniProt PMID:28755312 MGI:6368098 NCBI chr14:75,918,056...75,958,187
Ensembl chr14:75,918,171...75,958,183 		JBrowse link
G NUDT17 nudix hydrolase 17 involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr 4:99,472,347...99,477,953
Ensembl chr 4:99,472,350...99,477,932 		JBrowse link
G OGDH oxoglutarate dehydrogenase ISO RGD PMID:9712727 RGD:2306877 NCBI chr18:50,609,415...50,684,990
Ensembl chr18:50,609,418...50,684,964 		JBrowse link
G PC pyruvate carboxylase involved_in ISO (PMID:34547241) ComplexPortal PMID:34547241 NCBI chr 2:5,566,608...5,587,797
Ensembl chr 2:5,518,430...5,587,797 		JBrowse link
G VCP valosin containing protein involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 1:235,854,532...235,869,712
Ensembl chr 1:235,796,446...235,876,321 		JBrowse link
canonical glycolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENO1 enolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:69,385,879...69,401,664
Ensembl chr 6:69,385,882...69,401,117 		JBrowse link
G ENO2 enolase 2 involved_in ISO PMID:15041191 CAFA PMID:15041191 RGD:2302788 NCBI chr 5:63,799,927...63,809,067
Ensembl chr 5:63,799,339...63,836,688 		JBrowse link
G ENO3 enolase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:51,954,614...51,959,991
Ensembl chr12:51,954,614...51,963,223 		JBrowse link
G FOXK1 forkhead box K1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:30700909) Ensembl
Ensembl
UniProt		 PMID:30700909 GO_REF:0000107 NCBI chr 3:3,556,139...3,621,150
Ensembl chr 3:3,556,007...3,621,142 		JBrowse link
G FOXK2 forkhead box K2 involved_in
acts_upstream_of		 IEA
ISO		 (MGI:6281052|PMID:30700909) Ensembl
Ensembl
UniProt		 PMID:30700909 GO_REF:0000107 MGI:6281052 NCBI chr12:560,848...615,646
Ensembl chr12:562,074...615,747 		JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase involved_in ISO (MGI:2651735|PMID:12581789)
(MGI:6106926|PMID:28918937), (MGI:6861792|PMID:10777777)		 MGI PMID:10777777 PMID:12581789 PMID:28918937 MGI:2651735 MGI:6106926 MGI:6861792 NCBI chr 5:64,129,678...64,135,194
Ensembl chr 5:64,129,680...64,133,991 		JBrowse link
G HK1 hexokinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:72,383,328...72,460,927
Ensembl chr14:72,351,149...72,460,925 		JBrowse link
G PFKL phosphofructokinase, liver type involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr13:207,167,287...207,191,688
Ensembl chr13:207,167,372...207,191,690 		JBrowse link
G PFKM phosphofructokinase, muscle involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 (PMID:21873635)
(MGI:4356361|PMID:19696889)		 Ensembl
GO_Central
Ensembl
MGI
GO_Central		 PMID:19696889 PMID:21873635 GO_REF:0000107 MGI:4356361 NCBI chr 5:78,475,473...78,525,052
Ensembl chr 5:78,475,540...78,526,995 		JBrowse link
G PFKP phosphofructokinase, platelet involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr10:67,022,652...67,082,336
Ensembl chr10:67,022,652...67,082,451 		JBrowse link
G PGAM2 phosphoglycerate mutase 2 involved_in ISO (MGI:5543738|PMID:23951293) MGI PMID:23951293 MGI:5543738 NCBI chr18:48,693,832...48,712,787
Ensembl chr18:48,693,882...48,713,862 		JBrowse link
G PGK1 phosphoglycerate kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:62,187,472...62,210,321
Ensembl chr  X:62,187,431...62,212,244 		JBrowse link
G PKM pyruvate kinase, muscle involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:60,971,807...61,032,780 JBrowse link
G TPI1 triosephosphate isomerase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:63,839,473...63,842,853
Ensembl chr 5:63,837,506...63,843,137 		JBrowse link
glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LDHA lactate dehydrogenase A acts_upstream_of_or_within ISO (MGI:62497|PMID:8224816) MGI PMID:8224816 MGI:62497 NCBI chr 2:40,814,163...40,827,284
Ensembl chr 2:40,812,453...40,826,715 		JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase acts_upstream_of
involved_in		 ISO
IEA		 (MGI:4867601|PMID:20935145) MGI
Ensembl		 PMID:20935145 GO_REF:0000107 MGI:4867601 NCBI chr 5:66,044,679...66,067,571
Ensembl chr 5:66,044,686...66,067,377 		JBrowse link
G TP53 tumor protein p53 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:4867601|PMID:20935145) MGI
Ensembl		 PMID:20935145 GO_REF:0000107 MGI:4867601 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,643...52,953,819 		JBrowse link
glycerophosphate shuttle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPD1 glycerol-3-phosphate dehydrogenase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:1927687|PMID:11147825) Ensembl
Ensembl
MGI		 PMID:11147825 GO_REF:0000107 MGI:1927687 NCBI chr 5:16,008,179...16,021,676
Ensembl chr 5:16,007,448...16,017,825 		JBrowse link
NADH oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDOB aldolase, fructose-bisphosphate B involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 1:243,127,870...243,141,504
Ensembl chr 1:243,110,585...243,141,418 		JBrowse link
G GPD1 glycerol-3-phosphate dehydrogenase 1 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 (PMID:21873635)
(MGI:1927687|PMID:11147825)		 GO_Central
Ensembl
GO_Central
MGI
RGD		 PMID:9550546 PMID:11147825 PMID:21873635 GO_REF:0000107 MGI:1927687 RGD:1641824 NCBI chr 5:16,008,179...16,021,676
Ensembl chr 5:16,007,448...16,017,825 		JBrowse link
G GPD1L glycerol-3-phosphate dehydrogenase 1 like NOT|involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr13:18,126,471...18,176,669
Ensembl chr13:18,126,623...18,176,668 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 ISO RGD PMID:29389585 RGD:25823193 NCBI chr 6:17,292,962...17,302,593
Ensembl chr 6:17,292,769...17,302,590 		JBrowse link
G PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial ISO RGD PMID:19635791 RGD:7242950 NCBI chr 7:75,187,195...75,197,613
Ensembl chr 7:75,187,194...75,197,733 		JBrowse link
negative regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC25A12 solute carrier family 25 member 12 ISO RGD PMID:19764902 RGD:13628741 NCBI chr15:77,895,935...78,021,930
Ensembl chr15:77,895,935...78,098,383 		JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:4867601|PMID:20935145) Ensembl
Ensembl
MGI		 PMID:20935145 GO_REF:0000107 MGI:4867601 NCBI chr 5:66,044,679...66,067,571
Ensembl chr 5:66,044,686...66,067,377 		JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:4867601|PMID:20935145) Ensembl
Ensembl
MGI		 PMID:20935145 GO_REF:0000107 MGI:4867601 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,643...52,953,819 		JBrowse link
positive regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN3 actinin alpha 3 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 2:5,860,386...5,873,779
Ensembl chr 2:5,858,845...5,874,124 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17278
    metabolic process 10891
      NADH metabolic process 39
        NADH oxidation + 5
        NADH regeneration + 14
        glucose catabolic process to lactate via pyruvate + 5
        sulphoglycolysis 0
paths to the root