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ONTOLOGY REPORT - ANNOTATIONS

Term:NADH metabolic process
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Accession:GO:0006734 term browser browse the term
Definition:The chemical reactions and pathways involving reduced nicotinamide adenine dinucleotide (NADH), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.
Synonyms:exact_synonym: NADH metabolism;   reduced NAD metabolic process;   reduced NAD metabolism;   reduced nicotinamide adenine dinucleotide metabolic process;   reduced nicotinamide adenine dinucleotide metabolism


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NADH metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlst dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) involved_in ISO RGD
MGI		 PMID:9405249 GO_REF:0000096 MGI:4417868 RGD:1359804 NCBI chr12:85,157,597...85,180,865
Ensembl chr12:85,157,607...85,181,619 		JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 (soluble) involved_in ISO RGD
MGI		 PMID:12351438 GO_REF:0000096 MGI:4417868 RGD:2303499 NCBI chr15:99,615,468...99,622,895
Ensembl chr15:99,615,396...99,622,886 		JBrowse link
G Gpd1l glycerol-3-phosphate dehydrogenase 1-like acts_upstream_of_or_within IMP (MGI:4943631|PMID:19745168) MGI PMID:19745168 MGI:4943631 NCBI chr 9:114,728,407...114,763,055
Ensembl chr 9:114,728,409...114,763,055 		JBrowse link
G Gpd2 glycerol phosphate dehydrogenase 2, mitochondrial involved_in ISO RGD
MGI		 PMID:12351438 GO_REF:0000096 MGI:4417868 RGD:2303499 NCBI chr 2:57,127,690...57,260,731
Ensembl chr 2:57,127,647...57,260,731 		JBrowse link
G Idh3a isocitrate dehydrogenase 3 (NAD+) alpha involved_in ISO RGD
MGI		 PMID:938457 GO_REF:0000096 MGI:4417868 RGD:2306828 NCBI chr 9:54,493,795...54,511,946
Ensembl chr 9:54,493,618...54,511,945 		JBrowse link
G Idh3b isocitrate dehydrogenase 3 (NAD+) beta involved_in ISO RGD
MGI		 PMID:938457 GO_REF:0000096 MGI:4417868 RGD:2306828 NCBI chr 2:130,121,229...130,126,371
Ensembl chr 2:130,121,229...130,126,467 		JBrowse link
G Idh3g isocitrate dehydrogenase 3 (NAD+), gamma involved_in ISO RGD
MGI		 PMID:938457 GO_REF:0000096 MGI:4417868 RGD:2306828 NCBI chr  X:72,822,569...72,830,503
Ensembl chr  X:72,822,569...72,830,503 		JBrowse link
G Mdh1 malate dehydrogenase 1, NAD (soluble) involved_in IBA
ISO		 (MGI:6201960|PMID:21873635) GO_Central
MGI
RGD		 PMID:12351438 PMID:21873635 GO_REF:0000096 MGI:4417868 MGI:4834177 MGI:6201960 RGD:2303499 NCBI chr11:21,506,692...21,521,934
Ensembl chr11:21,506,692...21,522,367 		JBrowse link
G Mdh1b malate dehydrogenase 1B, NAD (soluble) involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 1:63,726,732...63,769,707
Ensembl chr 1:63,737,978...63,769,477 		JBrowse link
G Mdh2 malate dehydrogenase 2, NAD (mitochondrial) involved_in ISO RGD
MGI		 PMID:12351438 GO_REF:0000096 MGI:4417868 RGD:2303499 NCBI chr 5:135,807,503...135,819,240
Ensembl chr 5:135,807,334...135,819,252 		JBrowse link
G Me1 malic enzyme 1, NADP(+)-dependent, cytosolic involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:86,463,416...86,577,967
Ensembl chr 9:86,463,424...86,578,006 		JBrowse link
G Nudt12 nudix (nucleoside diphosphate linked moiety X)-type motif 12 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr17:59,307,104...59,320,317
Ensembl chr17:59,306,613...59,320,367 		JBrowse link
G Nudt13 nudix (nucleoside diphosphate linked moiety X)-type motif 13 involved_in IDA (MGI:6368098|PMID:28755312) UniProt PMID:28755312 MGI:6368098 NCBI chr14:20,344,709...20,367,652
Ensembl chr14:20,344,765...20,367,646 		JBrowse link
G Nudt17 nudix (nucleoside diphosphate linked moiety X)-type motif 17 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 3:96,613,208...96,616,233
Ensembl chr 3:96,613,383...96,615,878 		JBrowse link
G Ogdh oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) involved_in ISO RGD
MGI		 PMID:9712727 GO_REF:0000096 MGI:4417868 RGD:2306877 NCBI chr11:6,241,597...6,309,094
Ensembl chr11:6,241,633...6,306,642 		JBrowse link
G Pcx pyruvate carboxylase involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr19:4,560,500...4,671,780
Ensembl chr19:4,560,500...4,671,780 		JBrowse link
G Vcp valosin containing protein involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:42,979,964...43,000,507
Ensembl chr 4:42,979,963...43,000,507 		JBrowse link
canonical glycolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldoa aldolase A, fructose-bisphosphate involved_in IDA (MGI:5819300|PMID:28049690) MGI PMID:28049690 MGI:5819300 NCBI chr 7:126,394,406...126,400,166
Ensembl chr 7:126,394,406...126,399,923
Ensembl chr 7:126,394,406...126,399,923 		JBrowse link
G Eno1 enolase 1, alpha non-neuron involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:150,321,165...150,333,336
Ensembl chr 4:150,321,178...150,333,336 		JBrowse link
G Eno1b enolase 1B, retrotransposed involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr18:48,178,402...48,181,446
Ensembl chr18:48,178,402...48,181,479 		JBrowse link
G Eno2 enolase 2, gamma neuronal involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 6:124,737,016...124,746,636
Ensembl chr 6:124,737,016...124,746,636 		JBrowse link
G Eno3 enolase 3, beta muscle involved_in IGI (MGI:5892183|PMID:27760309) MGI PMID:27760309 MGI:5892183 NCBI chr11:70,543,973...70,553,339
Ensembl chr11:70,548,028...70,553,339 		JBrowse link
G Foxk1 forkhead box K1 acts_upstream_of ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:142,387,252...142,447,770
Ensembl chr 5:142,387,252...142,447,766 		JBrowse link
G Foxk2 forkhead box K2 acts_upstream_of IDA (MGI:6281052|PMID:30700909) UniProt PMID:30700909 MGI:6281052 NCBI chr11:121,150,805...121,200,726
Ensembl chr11:121,150,816...121,200,722 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase involved_in IDA
IMP		 (MGI:2651735|PMID:12581789)
(MGI:6106926|PMID:28918937), (MGI:6861792|PMID:10777777)		 MGI PMID:10777777 PMID:12581789 PMID:28918937 MGI:2651735 MGI:6106926 MGI:6861792 NCBI chr 6:125,138,815...125,143,430
Ensembl chr 6:125,138,678...125,143,430 		JBrowse link
G Gpi1 glucose-6-phosphate isomerase 1 involved_in TAS (MGI:5779586|PMID:27103217) MGI PMID:27103217 MGI:5779586 NCBI chr 7:33,900,752...33,929,761
Ensembl chr 7:33,900,755...33,929,761 		JBrowse link
G Hk1 hexokinase 1 acts_upstream_of_or_within
involved_in		 IC
IDA		 (MGI:3814792|PMID:18509164)
(MGI:6861806|PMID:4275392)		 MGI PMID:4275392 PMID:18509164 MGI:3814792 MGI:6861806 NCBI chr10:62,104,634...62,215,699
Ensembl chr10:62,104,634...62,215,687 		JBrowse link
G Pfkl phosphofructokinase, liver, B-type involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr10:77,822,781...77,845,641
Ensembl chr10:77,822,781...77,845,917 		JBrowse link
G Pfkm phosphofructokinase, muscle involved_in
acts_upstream_of_or_within		 IBA
IDA
IGI
IMP		 (MGI:6201960|PMID:21873635)
(MGI:5819300|PMID:28049690), (MGI:6861806|PMID:4275392)
(MGI:5892183|PMID:27760309)
(MGI:4356361|PMID:19696889)		 GO_Central
MGI		 PMID:4275392 PMID:19696889 PMID:21873635 PMID:27760309 PMID:28049690 MGI:4356361 MGI:5819300 MGI:5892183 MGI:6201960 MGI:6861806 NCBI chr15:97,990,470...98,030,328
Ensembl chr15:97,990,470...98,030,332 		JBrowse link
G Pfkp phosphofructokinase, platelet involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr13:6,629,910...6,699,096
Ensembl chr13:6,629,804...6,698,813 		JBrowse link
G Pgam2 phosphoglycerate mutase 2 involved_in IDA (MGI:5543738|PMID:23951293) MGI PMID:23951293 MGI:5543738 NCBI chr11:5,751,637...5,753,796
Ensembl chr11:5,751,640...5,753,733 		JBrowse link
G Pgk1 phosphoglycerate kinase 1 involved_in IGI (MGI:6857632|PMID:30174313) MGI PMID:30174313 MGI:6857632 NCBI chr  X:105,230,706...105,247,305
Ensembl chr  X:105,230,706...105,247,305 		JBrowse link
G Pkm pyruvate kinase, muscle involved_in IDA (MGI:5908042|PMID:28630053) MGI PMID:28630053 MGI:5908042 NCBI chr 9:59,563,859...59,586,655
Ensembl chr 9:59,563,651...59,586,658 		JBrowse link
G Tpi1 triosephosphate isomerase 1 involved_in IGI (MGI:6857632|PMID:30174313) MGI PMID:30174313 MGI:6857632 NCBI chr 6:124,787,549...124,791,121
Ensembl chr 6:124,787,549...124,791,259 		JBrowse link
glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldha lactate dehydrogenase A acts_upstream_of_or_within IMP (MGI:62497|PMID:8224816) MGI PMID:8224816 MGI:62497 NCBI chr 7:46,491,698...46,505,051
Ensembl chr 7:46,490,899...46,505,051 		JBrowse link
G Tigar Trp53 induced glycolysis regulatory phosphatase acts_upstream_of IMP (MGI:4867601|PMID:20935145) MGI PMID:20935145 MGI:4867601 NCBI chr 6:127,062,079...127,086,564
Ensembl chr 6:127,062,079...127,086,520 		JBrowse link
G Trp53 transformation related protein 53 acts_upstream_of IMP (MGI:4867601|PMID:20935145) MGI PMID:20935145 MGI:4867601 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
glycerophosphate shuttle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpd1 glycerol-3-phosphate dehydrogenase 1 (soluble) acts_upstream_of_or_within IMP (MGI:1927687|PMID:11147825) MGI PMID:11147825 MGI:1927687 NCBI chr15:99,615,468...99,622,895
Ensembl chr15:99,615,396...99,622,886 		JBrowse link
G Slc37a2 solute carrier family 37 (glycerol-3-phosphate transporter), member 2 acts_upstream_of_or_within ISA (MGI:1928161|PMID:11112347) MGI PMID:11112347 MGI:1928161 NCBI chr 9:37,140,445...37,167,034
Ensembl chr 9:37,138,881...37,167,034 		JBrowse link
NADH oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldob aldolase B, fructose-bisphosphate involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:49,535,993...49,549,546
Ensembl chr 4:49,535,995...49,549,546 		JBrowse link
G Cbr2 carbonyl reductase 2 acts_upstream_of_or_within TAS (MGI:2153337|PMID:8805511) MGI PMID:8805511 MGI:2153337 NCBI chr11:120,620,311...120,622,851
Ensembl chr11:120,620,315...120,622,940 		JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 (soluble) involved_in
acts_upstream_of_or_within		 IBA
ISO
IMP		 (MGI:6201960|PMID:21873635)
(MGI:1927687|PMID:11147825)		 GO_Central
MGI
RGD		 PMID:9550546 PMID:11147825 PMID:21873635 GO_REF:0000096 MGI:1927687 MGI:4417868 MGI:6201960 RGD:1641824 NCBI chr15:99,615,468...99,622,895
Ensembl chr15:99,615,396...99,622,886 		JBrowse link
G Gpd1l glycerol-3-phosphate dehydrogenase 1-like NOT|involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 9:114,728,407...114,763,055
Ensembl chr 9:114,728,409...114,763,055 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 involved_in ISO RGD
MGI		 PMID:29389585 GO_REF:0000096 MGI:4417868 RGD:25823193 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) involved_in ISO RGD
MGI		 PMID:19635791 GO_REF:0000096 MGI:4417868 RGD:7242950 NCBI chr14:55,777,721...55,787,477
Ensembl chr14:55,777,723...55,788,699 		JBrowse link
negative regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc25a12 solute carrier family 25 (mitochondrial carrier, Aralar), member 12 involved_in ISO RGD
MGI		 PMID:19764902 GO_REF:0000096 MGI:4417868 RGD:13628741 NCBI chr 2:71,104,614...71,198,125
Ensembl chr 2:71,101,407...71,198,093 		JBrowse link
G Tigar Trp53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within IMP (MGI:4867601|PMID:20935145) MGI PMID:20935145 MGI:4867601 NCBI chr 6:127,062,079...127,086,564
Ensembl chr 6:127,062,079...127,086,520 		JBrowse link
G Trp53 transformation related protein 53 acts_upstream_of_or_within IMP (MGI:4867601|PMID:20935145) MGI PMID:20935145 MGI:4867601 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
positive regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in IMP (MGI:3759354|PMID:17828264) UniProt PMID:17828264 MGI:3759354 NCBI chr19:4,911,244...4,927,937
Ensembl chr19:4,911,244...4,927,937 		JBrowse link
G Mir210 microRNA 210 involved_in ISO (PMID:20436681) ARUK-UCL PMID:20436681 NCBI chr 7:140,801,297...140,801,406
Ensembl chr 7:140,801,297...140,801,406 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28739
    metabolic process 11540
      NADH metabolic process 45
        NADH oxidation + 7
        NADH regeneration + 17
        glucose catabolic process to lactate via pyruvate + 6
        sulphoglycolysis 0
paths to the root