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ONTOLOGY REPORT - ANNOTATIONS


Term:one-carbon metabolic process
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Accession:GO:0006730 term browser browse the term
Definition:The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.
Synonyms:exact_synonym: one carbon metabolism;   one-carbon transfer metabolic process;   one-carbon transfer metabolism
 alt_id: GO:0019753;   GO:0019754
 xref: UM-BBD_pathwayID:C1cyc


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one-carbon metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnmt glycine N-methyltransferase acts_upstream_of_or_within ISO (MGI:3842675|PMID:17937387) MGI PMID:17937387 MGI:3842675 NCBI chrNW_004936476:16,961,734...16,965,487 JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:25633902) RGD
BHF-UCL
PMID:14597174 PMID:25633902 RGD:1302361 NCBI chrNW_004936495:8,100,977...8,170,244 JBrowse link
G Sfxn1 sideroflexin 1 acts_upstream_of ISO (PMID:30442778) UniProt PMID:30442778 NCBI chrNW_004936609:727,621...754,806 JBrowse link
G Sfxn3 sideroflexin 3 acts_upstream_of ISO (PMID:30442778) UniProt PMID:30442778 NCBI chrNW_004936600:4,650,765...4,659,641 JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 involved_in ISO (PMID:11516159), (PMID:29180469), (PMID:29364879), (PMID:29452640) UniProt PMID:11516159 PMID:29180469 PMID:29364879 PMID:29452640 NCBI chrNW_004936646:1,422,844...1,427,929 JBrowse link
tetrahydrofolate interconversion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmgdh dimethylglycine dehydrogenase ISO RGD PMID:6163778 RGD:7245485 NCBI chrNW_004936549:6,838,773...6,899,961 JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:1881876)
(MGI:5503248|PMID:23704330)
BHF-UCL PMID:1881876 PMID:23704330 MGI:5503248 NCBI chrNW_004936495:8,100,977...8,170,244 JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like ISO RGD PMID:21163947 RGD:7244288 NCBI chrNW_004936598:1,401,392...1,514,314 JBrowse link
G Mthfr methylenetetrahydrofolate reductase involved_in ISO (PMID:12673793)
(PMID:10551815)
(PMID:12673793), (PMID:25736335)
BHF-UCL PMID:10551815 PMID:12673793 PMID:25736335 NCBI chrNW_004936474:623,438...637,849 JBrowse link
G Mthfs methenyltetrahydrofolate synthetase involved_in ISO (PMID:12764149) BHF-UCL PMID:12764149 NCBI chrNW_004936471:37,910,856...37,964,655 JBrowse link
G Sardh sarcosine dehydrogenase ISO RGD PMID:6163778 RGD:7245485 NCBI chrNW_004936669:3,244,302...3,297,906 JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 involved_in ISO (PMID:24698160) BHF-UCL PMID:24698160 NCBI chrNW_004936741:1,849,239...1,877,724 JBrowse link
G Tyms thymidylate synthetase involved_in ISO (PMID:15093541) BHF-UCL PMID:15093541 NCBI chrNW_004936550:33,797...42,233 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12130
    metabolic process 7625
      cellular metabolic process 7005
        one-carbon metabolic process 12
          serine-isocitrate lyase pathway 0
          tetrahydrofolate interconversion 8
paths to the root