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ONTOLOGY REPORT - ANNOTATIONS


Term:one-carbon metabolic process
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Accession:GO:0006730 term browser browse the term
Definition:The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.
Synonyms:exact_synonym: one carbon metabolism;   one-carbon transfer metabolic process;   one-carbon transfer metabolism
 alt_id: GO:0019753;   GO:0019754
 xref: UM-BBD_pathwayID:C1cyc


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one-carbon metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahcy adenosylhomocysteinase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:150,587,833...150,603,057
Ensembl chr 3:150,587,833...150,603,082
JBrowse link
G Ahcyl1 adenosylhomocysteinase-like 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:210,438,884...210,474,350
Ensembl chr 2:210,438,893...210,473,761
JBrowse link
G Ahcyl2 adenosylhomocysteinase-like 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 4:57,050,241...57,199,870
Ensembl chr 4:57,050,214...57,199,900
JBrowse link
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 4:123,516,553...123,564,067
Ensembl chr 4:123,516,788...123,557,501
JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:26,375,866...26,425,838
Ensembl chr 7:26,375,866...26,425,108
JBrowse link
G Ca11 carbonic anhydrase 11 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:101,682,009...101,687,358
Ensembl chr 1:101,682,172...101,687,293
JBrowse link
G Ca12 carbonic anhydrase 12 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:72,405,770...72,461,425
Ensembl chr 8:72,405,748...72,460,240
JBrowse link
G Ca13 carbonic anhydrase 13 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:88,282,961...88,314,254
Ensembl chr 2:88,282,961...88,314,254
JBrowse link
G Ca14 carbonic anhydrase 14 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:198,010,142...198,017,635
Ensembl chr 2:198,010,349...198,016,898
JBrowse link
G Ca3 carbonic anhydrase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
JBrowse link
G Ca4 carbonic anhydrase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:72,272,286...72,281,069
Ensembl chr10:72,272,248...72,281,067
JBrowse link
G Ca5a carbonic anhydrase 5A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:54,731,829...54,761,697
Ensembl chr19:54,731,859...54,761,670
JBrowse link
G Ca5b carbonic anhydrase 5B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:32,232,106...32,291,124
Ensembl chr  X:32,232,142...32,292,072
JBrowse link
G Ca6 carbonic anhydrase 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:167,226,246...167,244,786
Ensembl chr 5:167,226,246...167,244,786
JBrowse link
G Ca8 carbonic anhydrase 8 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:21,249,018...21,345,810
Ensembl chr 5:21,249,020...21,345,810
JBrowse link
G Ca9 carbonic anhydrase 9 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:59,008,277...59,015,535
Ensembl chr 5:59,008,933...59,015,528
JBrowse link
G Car1 carbonic anhydrase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:88,185,204...88,227,486
Ensembl chr 2:88,217,188...88,227,479
JBrowse link
G Car10 carbonic anhydrase 10 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:80,790,151...81,297,621
Ensembl chr10:80,790,168...81,296,363
JBrowse link
G Car15 carbonic anhydrase 15 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:87,293,827...87,298,690
Ensembl chr11:87,295,182...87,298,775
Ensembl chr11:87,295,182...87,298,775
JBrowse link
G Car2 carbonic anhydrase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Car7 carbonic anhydrase 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:636,545...645,935
Ensembl chr19:636,545...645,937
JBrowse link
G Dhfr dihydrofolate reductase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:21,931,887...21,958,927
Ensembl chr 2:21,931,493...21,962,453
JBrowse link
G Gnmt glycine N-methyltransferase involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3842652 (MGI:3842675|PMID:17937387)
RGD PMID:17937387, PMID:21873635 MGI:3842675, RGD:13792537 NCBI chr 9:16,565,274...16,568,626
Ensembl chr 9:16,565,225...16,568,627
JBrowse link
G Mat1a methionine adenosyltransferase 1A involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr16:18,690,649...18,709,135
Ensembl chr16:18,690,246...18,709,133
JBrowse link
G Mat2a methionine adenosyltransferase 2A involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 4:100,297,478...100,303,047
Ensembl chr 4:100,296,075...100,303,080
JBrowse link
G Mat2b methionine adenosyltransferase 2B involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:25,832,096...25,848,045
Ensembl chr10:25,832,072...25,847,994
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in IEP
ISO
(PMID:25633902) RGD PMID:25633902, PMID:14597174 RGD:1302361 NCBI chr 6:99,282,850...99,350,367
Ensembl chr 6:99,282,850...99,350,340
JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:18,640,274...18,721,298
Ensembl chr14:18,640,277...18,720,357
JBrowse link
G Sfxn1 sideroflexin 1 involved_in
acts_upstream_of
IEA
ISO
ISS
GO_REF:0000107
(PMID:30442778)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:30442778 GO_REF:0000024 GO_REF:0000107 NCBI chr17:11,046,588...11,082,219
Ensembl chr17:11,045,761...11,082,047
JBrowse link
G Sfxn3 sideroflexin 3 acts_upstream_of
involved_in
ISO
IEA
ISS
(PMID:30442778)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:30442778 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:264,796,671...264,805,159
Ensembl chr 1:264,796,812...264,805,157
JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:47,030,813...47,059,216
Ensembl chr10:47,031,050...47,059,216
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 involved_in ISO
IBA
(PMID:11516159), (PMID:29180469), (PMID:29364879), (PMID:29452640)
PMID:21873635
RGD PMID:11516159 PMID:29180469 PMID:29364879 PMID:29452640, PMID:21873635 RGD:13792537 NCBI chr 7:70,824,718...70,829,822
Ensembl chr 7:70,824,715...70,829,815
JBrowse link
tetrahydrofolate interconversion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmgdh dimethylglycine dehydrogenase IDA RGD PMID:6163778 RGD:7245485 NCBI chr 2:23,289,376...23,370,360
Ensembl chr 2:23,289,374...23,370,477
JBrowse link
G Ftcd formimidoyltransferase cyclodeaminase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr20:12,806,957...12,820,466
Ensembl chr20:12,806,957...12,820,466
JBrowse link
G LOC680432 similar to methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase involved_in IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 3:121,490,787...121,493,932
Ensembl chr 3:121,490,812...121,493,714
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in IEA
ISO
IBA
GO_REF:0000041
(MGI:5503248|PMID:23704330)
PMID:21873635
(PMID:1881876)
UniProt
RGD
PMID:1881876 PMID:23704330, PMID:21873635 GO_REF:0000041 MGI:5503248, RGD:13792537 NCBI chr 6:99,282,850...99,350,367
Ensembl chr 6:99,282,850...99,350,340
JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like involved_in IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 1:40,529,092...40,719,232
Ensembl chr 1:40,529,045...40,719,391
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:115,004,433...115,015,965
Ensembl chr 4:115,004,448...115,015,965
JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like involved_in IDA
IEA
IBA
GO_REF:0000041
PMID:21873635
UniProt PMID:21163947, PMID:21873635 GO_REF:0000041, RGD:7244288, RGD:13792537 NCBI chr14:18,640,274...18,721,298
Ensembl chr14:18,640,277...18,720,357
JBrowse link
G Mthfr methylenetetrahydrofolate reductase involved_in ISO
IBA
IEA
UniProtKB:P53128 (PMID:10551815), (PMID:12673793), (PMID:25736335)
PMID:21873635
GO_REF:0000041
RGD
UniProt
PMID:10551815 PMID:12673793 PMID:25736335, PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Mthfs methenyltetrahydrofolate synthetase involved_in ISO
IBA
(PMID:12764149)
PMID:21873635
RGD PMID:12764149, PMID:21873635 RGD:13792537 NCBI chr 8:96,564,877...96,614,386
Ensembl chr 8:96,564,877...96,614,348
JBrowse link
G Sardh sarcosine dehydrogenase IDA RGD PMID:6163778 RGD:7245485 NCBI chr 3:5,737,203...5,802,153
Ensembl chr 3:5,737,200...5,802,129
JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 involved_in IBA
IEA
ISO
PMID:21873635
GO_REF:0000041
(PMID:24698160)
UniProt
RGD
PMID:24698160, PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr10:47,030,813...47,059,216
Ensembl chr10:47,031,050...47,059,216
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 involved_in IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 7:70,824,718...70,829,822
Ensembl chr 7:70,824,715...70,829,815
JBrowse link
G Tyms thymidylate synthetase involved_in ISO (PMID:15093541) RGD PMID:15093541 NCBI chr 9:121,918,875...121,931,564
Ensembl chr 9:121,918,947...121,931,564
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    metabolic process 11881
      cellular metabolic process 10838
        one-carbon metabolic process 41
          serine-isocitrate lyase pathway 0
          tetrahydrofolate interconversion 13
paths to the root