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ONTOLOGY REPORT - ANNOTATIONS


Term:one-carbon metabolic process
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Accession:GO:0006730 term browser browse the term
Definition:The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.
Synonyms:exact_synonym: one carbon metabolism;   one-carbon transfer metabolic process;   one-carbon transfer metabolism
 alt_id: GO:0019753;   GO:0019754
 xref: UM-BBD_pathwayID:C1cyc


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one-carbon metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahcyl1 S-adenosylhomocysteine hydrolase-like 1 acts_upstream_of_or_within IEA UniProt GO_REF:0000004 MGI:1354194 NCBI chr 3:107,663,120...107,696,560
Ensembl chr 3:107,663,118...107,696,560
JBrowse link
G Ahcyl2 S-adenosylhomocysteine hydrolase-like 2 acts_upstream_of_or_within IEA UniProt GO_REF:0000004 MGI:1354194 NCBI chr 6:29,768,379...29,912,310
Ensembl chr 6:29,768,011...29,912,310
JBrowse link
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 acts_upstream_of_or_within
involved_in
IEA UniProt GO_REF:0000002 GO_REF:0000004 MGI:1354194 MGI:2152098 NCBI chr 6:90,550,768...90,599,171
Ensembl chr 6:90,486,427...90,600,203
JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 involved_in
acts_upstream_of_or_within
IEA UniProt GO_REF:0000002 GO_REF:0000004 MGI:1354194 MGI:2152098 NCBI chr10:83,487,447...83,534,146
Ensembl chr10:83,487,450...83,534,140
JBrowse link
G Car1 carbonic anhydrase 1 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 3:14,766,214...14,808,365
Ensembl chr 3:14,766,216...14,808,368
JBrowse link
G Car10 carbonic anhydrase 10 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr11:93,096,805...93,601,751
Ensembl chr11:93,098,028...93,601,749
JBrowse link
G Car11 carbonic anhydrase 11 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 7:45,699,171...45,704,687
Ensembl chr 7:45,699,843...45,704,682
JBrowse link
G Car12 carbonic anhydrase 12 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 9:66,712,296...66,766,845
Ensembl chr 9:66,713,686...66,766,845
JBrowse link
G Car13 carbonic anhydrase 13 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 3:14,641,727...14,663,002
Ensembl chr 3:14,641,727...14,663,002
JBrowse link
G Car14 carbonic anhydrase 14 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 3:95,897,768...95,905,117
Ensembl chr 3:95,897,768...95,904,691
JBrowse link
G Car15 carbonic anhydrase 15 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr16:17,835,276...17,838,186
Ensembl chr16:17,835,276...17,838,364
JBrowse link
G Car2 carbonic anhydrase 2 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 3:14,886,269...14,900,770
Ensembl chr 3:14,886,273...14,900,770
JBrowse link
G Car3 carbonic anhydrase 3 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 3:14,863,538...14,872,381
Ensembl chr 3:14,863,512...14,872,523
JBrowse link
G Car4 carbonic anhydrase 4 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr11:84,957,754...84,966,054
Ensembl chr11:84,957,786...84,966,044
JBrowse link
G Car5a carbonic anhydrase 5a, mitochondrial involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 8:121,916,135...121,944,912
Ensembl chr 8:121,916,126...121,944,904
JBrowse link
G Car5b carbonic anhydrase 5b, mitochondrial involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr  X:163,976,822...164,028,010
Ensembl chr  X:163,976,822...164,027,997
JBrowse link
G Car6 carbonic anhydrase 6 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 4:150,187,015...150,201,135
Ensembl chr 4:150,187,015...150,201,332
JBrowse link
G Car7 carbonic anhydrase 7 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 8:104,534,694...104,550,347
Ensembl chr 8:104,534,689...104,550,343
JBrowse link
G Car8 carbonic anhydrase 8 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 4:8,141,493...8,239,041
Ensembl chr 4:8,143,362...8,239,041
JBrowse link
G Car9 carbonic anhydrase 9 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 4:43,507,026...43,513,729
Ensembl chr 4:43,506,966...43,513,729
JBrowse link
G Dhfr dihydrofolate reductase acts_upstream_of_or_within IEA UniProt GO_REF:0000004 MGI:1354194 NCBI chr13:92,354,783...92,389,053
Ensembl chr13:92,354,726...92,389,053
JBrowse link
G Fpgs folylpolyglutamyl synthetase acts_upstream_of_or_within IEA UniProt GO_REF:0000004 MGI:1354194 NCBI chr 2:32,682,609...32,704,196
Ensembl chr 2:32,682,609...32,704,145
JBrowse link
G Gnmt glycine N-methyltransferase involved_in
acts_upstream_of_or_within
IBA
IMP
(MGI:6201960|PMID:21873635)
(MGI:3842675|PMID:17937387)
GO_Central
MGI
PMID:17937387 PMID:21873635 MGI:3842675 MGI:6201960 NCBI chr17:46,725,664...46,729,211
Ensembl chr17:46,725,664...46,729,168
JBrowse link
G Mat1a methionine adenosyltransferase I, alpha acts_upstream_of_or_within IEA UniProt GO_REF:0000004 MGI:1354194 NCBI chr14:41,105,012...41,124,428
Ensembl chr14:41,105,035...41,124,412
JBrowse link
G Mat2a methionine adenosyltransferase II, alpha acts_upstream_of_or_within IEA UniProt GO_REF:0000004 MGI:1354194 NCBI chr 6:72,432,796...72,439,556
Ensembl chr 6:72,432,799...72,439,558
JBrowse link
G Mat2b methionine adenosyltransferase II, beta acts_upstream_of_or_within IEA UniProt GO_REF:0000004 MGI:1354194 NCBI chr11:40,679,314...40,695,203
Ensembl chr11:40,679,314...40,695,203
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase involved_in ISO MGI
RGD
PMID:14597174 GO_REF:0000096 MGI:4834177 RGD:1302361 NCBI chr12:76,254,406...76,319,820
Ensembl chr12:76,255,298...76,319,803
JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like acts_upstream_of_or_within IEA UniProt GO_REF:0000004 MGI:1354194 NCBI chr10:3,972,892...4,167,081
Ensembl chr10:3,973,118...4,167,081
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase acts_upstream_of_or_within IEA UniProt GO_REF:0000004 MGI:1354194 NCBI chr 6:83,305,704...83,326,011
Ensembl chr 6:83,305,691...83,325,908
JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like acts_upstream_of_or_within IEA UniProt GO_REF:0000004 MGI:1354194 NCBI chr 5:90,930,873...91,021,368
Ensembl chr 5:90,931,117...91,021,368
JBrowse link
G Sfxn1 sideroflexin 1 acts_upstream_of ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr13:54,071,656...54,108,346
Ensembl chr13:54,071,869...54,108,342
JBrowse link
G Sfxn3 sideroflexin 3 acts_upstream_of ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr19:45,046,773...45,056,383
Ensembl chr19:45,047,503...45,056,383
JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 (soluble) involved_in IC
IBA
(MGI:3849912|PMID:19513116)
(MGI:6201960|PMID:21873635)
BHF-UCL
GO_Central
PMID:19513116 PMID:21873635 MGI:3849912 MGI:6201960 NCBI chr11:60,788,897...60,811,265
Ensembl chr11:60,788,104...60,811,718
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 (mitochondrial) involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr10:127,517,123...127,522,444
Ensembl chr10:127,517,123...127,522,444
JBrowse link
tetrahydrofolate interconversion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmgdh dimethylglycine dehydrogenase precursor acts_upstream_of_or_within ISO MGI
RGD
PMID:6163778 GO_REF:0000096 MGI:4417868 RGD:7245485 NCBI chr13:93,674,436...93,752,823
Ensembl chr13:93,674,433...93,752,833
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase involved_in IBA
IMP
ISO
(MGI:6201960|PMID:21873635)
(MGI:5503248|PMID:23704330)
GO_Central
BHF-UCL
MGI
PMID:21873635 PMID:23704330 GO_REF:0000096 MGI:4834177 MGI:5503248 MGI:6201960 NCBI chr12:76,254,406...76,319,820
Ensembl chr12:76,255,298...76,319,803
JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr10:3,972,892...4,167,081
Ensembl chr10:3,973,118...4,167,081
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 6:83,305,704...83,326,011
Ensembl chr 6:83,305,691...83,325,908
JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:6201960|PMID:21873635) MGI
RGD
GO_Central
PMID:21163947 PMID:21873635 GO_REF:0000096 MGI:4417868 MGI:6201960 RGD:7244288 NCBI chr 5:90,930,873...91,021,368
Ensembl chr 5:90,931,117...91,021,368
JBrowse link
G Mthfr methylenetetrahydrofolate reductase involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 4:148,039,077...148,059,562
Ensembl chr 4:148,039,077...148,059,551
JBrowse link
G Mthfs 5, 10-methenyltetrahydrofolate synthetase involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 9:89,211,190...89,240,225
Ensembl chr 9:89,210,676...89,377,713
JBrowse link
G Mthfsl 5, 10-methenyltetrahydrofolate synthetase-like involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 9:88,685,630...88,720,320
Ensembl chr 9:88,688,602...88,720,296
JBrowse link
G Sardh sarcosine dehydrogenase acts_upstream_of_or_within ISO MGI
RGD
PMID:6163778 GO_REF:0000096 MGI:4417868 RGD:7245485 NCBI chr 2:27,188,393...27,248,332
Ensembl chr 2:27,188,393...27,248,337
JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 (soluble) involved_in ISO
IBA
(MGI:6201960|PMID:21873635) MGI
GO_Central
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr11:60,788,897...60,811,265
Ensembl chr11:60,788,104...60,811,718
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 (mitochondrial) involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr10:127,517,123...127,522,444
Ensembl chr10:127,517,123...127,522,444
JBrowse link
G Tyms thymidylate synthase involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:30,038,546...30,073,645
Ensembl chr 5:30,058,202...30,073,617
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28589
    metabolic process 11111
      cellular metabolic process 9990
        one-carbon metabolic process 40
          serine-isocitrate lyase pathway 0
          tetrahydrofolate interconversion 12
paths to the root