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ONTOLOGY REPORT - ANNOTATIONS


Term:one-carbon metabolic process
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Accession:GO:0006730 term browser browse the term
Definition:The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.
Synonyms:exact_synonym: one carbon metabolism;   one-carbon transfer metabolic process;   one-carbon transfer metabolism
 alt_id: GO:0019753;   GO:0019754
 xref: UM-BBD_pathwayID:C1cyc


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one-carbon metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHCY adenosylhomocysteinase involved_in IEA UniProt GO_REF:0000043 NCBI chr24:23,410,553...23,423,494
Ensembl chr24:23,411,140...23,419,767
JBrowse link
G AHCYL1 adenosylhomocysteinase like 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 6:41,945,224...41,983,917
Ensembl chr 6:41,946,974...41,985,643
JBrowse link
G AHCYL2 adenosylhomocysteinase like 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr14:7,347,173...7,509,113
Ensembl chr14:7,350,102...7,509,157
JBrowse link
G ALDH1L2 aldehyde dehydrogenase 1 family member L2 involved_in IEA UniProt GO_REF:0000043 NCBI chr10:33,310,523...33,365,677
Ensembl chr10:33,310,558...33,365,228
JBrowse link
G CA1 carbonic anhydrase 1 involved_in IEA
IBA
(PMID:21873635) InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr29:31,858,644...31,868,135
Ensembl chr29:31,858,636...31,868,158
JBrowse link
G CA10 carbonic anhydrase 10 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:27,382,508...27,863,806
Ensembl chr 9:27,383,588...27,862,086
JBrowse link
G CA11 carbonic anhydrase 11 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:107,669,184...107,674,825
Ensembl chr 1:107,669,419...107,674,792
JBrowse link
G CA12 carbonic anhydrase 12 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr30:27,903,460...27,957,162
Ensembl chr30:27,905,837...27,957,742
JBrowse link
G CA13 carbonic anhydrase 13 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr29:31,784,614...31,833,429
Ensembl chr29:31,782,680...31,850,405
JBrowse link
G CA2 carbonic anhydrase 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr29:31,959,225...31,975,309
Ensembl chr29:31,935,172...31,980,579
JBrowse link
G CA3 carbonic anhydrase 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr29:31,935,192...31,945,585
Ensembl chr29:31,935,172...31,980,579
JBrowse link
G CA4 carbonic anhydrase 4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:36,327,919...36,337,103
Ensembl chr 9:36,327,969...36,337,088
JBrowse link
G CA5A carbonic anhydrase 5A involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:65,269,855...65,297,593
Ensembl chr 5:65,269,635...65,296,777
JBrowse link
G CA5B carbonic anhydrase 5B involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:11,908,426...12,042,327
Ensembl chr  X:11,930,884...12,040,221
JBrowse link
G CA6 carbonic anhydrase 6 involved_in IEA
IBA
(PMID:21873635) InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr 5:62,358,521...62,379,901
Ensembl chr 5:62,358,403...62,379,897
JBrowse link
G CA7 carbonic anhydrase 7 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:82,446,239...82,455,445
Ensembl chr 5:82,446,246...82,455,590
JBrowse link
G CA8 carbonic anhydrase 8 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr29:10,678,122...10,763,361
Ensembl chr29:10,679,038...10,764,193
JBrowse link
G CA9 carbonic anhydrase 9 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:52,205,619...52,211,281
Ensembl chr11:52,205,668...52,211,267
JBrowse link
G FPGS folylpolyglutamate synthase involved_in IEA UniProt GO_REF:0000043 NCBI chr 9:55,590,092...55,612,639
Ensembl chr 9:55,585,970...55,599,028
JBrowse link
G GNMT glycine N-methyltransferase involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:3842675|PMID:17937387)
GO_Central
MGI
PMID:17937387 PMID:21873635 MGI:3842675 NCBI chr12:11,500,363...11,503,075
Ensembl chr12:11,500,392...11,503,481
JBrowse link
G LOC609048 dihydrofolate reductase involved_in IEA UniProt GO_REF:0000043 NCBI chr19:16,731,187...16,731,854 JBrowse link
G MAT1A methionine adenosyltransferase 1A involved_in IEA UniProt GO_REF:0000043 NCBI chr 4:29,450,857...29,467,251
Ensembl chr 4:29,452,601...29,466,929
JBrowse link
G MAT2A methionine adenosyltransferase 2A involved_in IEA UniProt GO_REF:0000043 NCBI chr17:39,525,635...39,532,512
Ensembl chr17:39,525,626...39,532,512
JBrowse link
G MAT2B methionine adenosyltransferase 2B involved_in IEA UniProt GO_REF:0000043 NCBI chr 4:47,703,991...47,726,363
Ensembl chr 4:47,709,576...47,726,360
JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:25633902) RGD
BHF-UCL
PMID:14597174 PMID:25633902 RGD:1302361 NCBI chr 8:38,831,672...38,889,607
Ensembl chr 8:38,831,860...38,889,453
JBrowse link
G MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase involved_in IEA UniProt GO_REF:0000043 NCBI chr17:48,882,838...48,896,816
Ensembl chr17:48,883,724...48,941,949
JBrowse link
G MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like involved_in IEA UniProt GO_REF:0000043 NCBI chr13:62,670,543...62,803,270
Ensembl chr13:62,670,462...62,803,519
JBrowse link
G SFXN1 sideroflexin 1 involved_in
acts_upstream_of
IEA
ISO
(PMID:30442778) Ensembl
UniProt
PMID:30442778 GO_REF:0000107 NCBI chr 4:37,485,360...37,517,743
Ensembl chr 4:37,487,438...37,512,289
JBrowse link
G SFXN3 sideroflexin 3 acts_upstream_of
involved_in
ISO
IEA
(PMID:30442778) UniProt
Ensembl
PMID:30442778 GO_REF:0000107 NCBI chr28:13,712,846...13,720,302
Ensembl chr28:13,712,891...13,718,926
JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:41,221,531...41,248,653
Ensembl chr 5:41,221,562...41,253,166
JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:1,357,347...1,362,511
Ensembl chr10:1,356,706...1,362,305
JBrowse link
tetrahydrofolate interconversion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DMGDH dimethylglycine dehydrogenase ISO RGD PMID:6163778 RGD:7245485 NCBI chr 3:27,789,089...27,857,348
Ensembl chr 3:27,790,324...27,856,601
JBrowse link
G FTCD formimidoyltransferase cyclodeaminase involved_in IEA UniProt GO_REF:0000041 NCBI chr31:39,451,557...39,464,249
Ensembl chr31:39,275,159...39,464,715
JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in IEA
IBA
(PMID:21873635) UniProt
GO_Central
PMID:21873635 GO_REF:0000041 NCBI chr 8:38,831,672...38,889,607
Ensembl chr 8:38,831,860...38,889,453
JBrowse link
G MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like involved_in IEA
IBA
(PMID:21873635) UniProt
GO_Central
PMID:21873635 GO_REF:0000041 NCBI chr 1:41,316,247...41,495,226
Ensembl chr 1:41,309,419...41,495,216
JBrowse link
G MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:48,882,838...48,896,816
Ensembl chr17:48,883,724...48,941,949
JBrowse link
G MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like involved_in IBA
ISO
(PMID:21873635) GO_Central
RGD
PMID:21163947 PMID:21873635 RGD:7244288 NCBI chr13:62,670,543...62,803,270
Ensembl chr13:62,670,462...62,803,519
JBrowse link
G MTHFR methylenetetrahydrofolate reductase involved_in IBA
IEA
(PMID:21873635) GO_Central
UniProt
PMID:21873635 GO_REF:0000041 NCBI chr 2:84,445,526...84,457,435
Ensembl chr 2:84,380,919...84,536,818
JBrowse link
G MTHFS methenyltetrahydrofolate synthetase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:57,480,935...57,514,836 JBrowse link
G SARDH sarcosine dehydrogenase ISO RGD PMID:6163778 RGD:7245485 NCBI chr 9:50,030,397...50,093,556
Ensembl chr 9:50,030,707...50,091,553
JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 involved_in IEA
IBA
(PMID:21873635) UniProt
GO_Central
PMID:21873635 GO_REF:0000041 NCBI chr 5:41,221,531...41,248,653
Ensembl chr 5:41,221,562...41,253,166
JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 involved_in IEA
IBA
(PMID:21873635) UniProt
GO_Central
PMID:21873635 GO_REF:0000041 NCBI chr10:1,357,347...1,362,511
Ensembl chr10:1,356,706...1,362,305
JBrowse link
G TYMS thymidylate synthetase involved_in ISO (PMID:15093541) BHF-UCL PMID:15093541 NCBI chr 7:67,487,927...67,497,747
Ensembl chr 7:67,487,927...67,497,747
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 16211
    metabolic process 10509
      cellular metabolic process 9576
        one-carbon metabolic process 38
          serine-isocitrate lyase pathway 0
          tetrahydrofolate interconversion 12
paths to the root