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ONTOLOGY REPORT - ANNOTATIONS


Term:one-carbon metabolic process
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Accession:GO:0006730 term browser browse the term
Definition:The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.
Synonyms:exact_synonym: one carbon metabolism;   one-carbon transfer metabolic process;   one-carbon transfer metabolism
 alt_id: GO:0019753;   GO:0019754
 xref: UM-BBD_pathwayID:C1cyc


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one-carbon metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnmt glycine N-methyltransferase acts_upstream_of_or_within ISO (PMID:17937387) MGI PMID:17937387 NCBI chrNW_004955437:8,944,288...8,946,642
Ensembl chrNW_004955437:8,944,047...8,946,642
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:25633902) RGD
BHF-UCL
PMID:14597174 PMID:25633902 RGD:1302361 NCBI chrNW_004955466:5,422,141...5,485,773
Ensembl chrNW_004955466:5,420,702...5,485,773
JBrowse link
G Sfxn1 sideroflexin 1 acts_upstream_of ISO (PMID:30442778) UniProt PMID:30442778 NCBI chrNW_004955408:28,054,211...28,105,294
Ensembl chrNW_004955408:28,054,211...28,106,175
JBrowse link
G Sfxn3 sideroflexin 3 acts_upstream_of ISO (PMID:30442778) UniProt PMID:30442778 NCBI chrNW_004955485:9,157,657...9,165,243
Ensembl chrNW_004955485:9,157,657...9,165,243
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 involved_in ISO (PMID:11516159), (PMID:29180469), (PMID:29364879), (PMID:29452640)
(PMID:33015733)
UniProt PMID:11516159 PMID:29180469 PMID:29364879 PMID:29452640 PMID:33015733 NCBI chrNW_004955458:4,957,614...4,962,691
Ensembl chrNW_004955458:4,957,602...4,962,691
JBrowse link
tetrahydrofolate interconversion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhfr dihydrofolate reductase involved_in ISO (PMID:360074) MGI PMID:360074 NCBI chrNW_004955418:29,274,170...29,283,028 JBrowse link
G Dmgdh dimethylglycine dehydrogenase ISO RGD PMID:6163778 RGD:7245485 NCBI chrNW_004955425:22,045,977...22,103,381
Ensembl chrNW_004955425:22,045,993...22,102,852
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (MGI:5503248|PMID:23704330)
(PMID:10828945), (PMID:1881876)
BHF-UCL PMID:1881876 PMID:10828945 PMID:23704330 MGI:5503248 NCBI chrNW_004955466:5,422,141...5,485,773
Ensembl chrNW_004955466:5,420,702...5,485,773
JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like involved_in ISO PMID:24733394 RGD
UniProt
PMID:21163947 PMID:24733394 RGD:150521648 RGD:7244288 NCBI chrNW_004955474:450,676...558,659
Ensembl chrNW_004955474:450,680...558,716
JBrowse link
G Mthfr methylenetetrahydrofolate reductase involved_in ISO (PMID:10551815)
(PMID:12673793), (PMID:29891918)
(PMID:12673793), (PMID:25736335)
BHF-UCL
UniProt
PMID:10551815 PMID:12673793 PMID:25736335 PMID:29891918 NCBI chrNW_004955486:2,096,379...2,112,240
Ensembl chrNW_004955486:2,096,379...2,112,240
JBrowse link
G Mthfs methenyltetrahydrofolate synthetase involved_in ISO (PMID:12764149) BHF-UCL PMID:12764149 NCBI chrNW_004955533:720,255...756,893
Ensembl chrNW_004955533:720,353...756,893
JBrowse link
G Sardh sarcosine dehydrogenase ISO RGD PMID:6163778 RGD:7245485 NCBI chrNW_004955513:2,933,918...2,975,645
Ensembl chrNW_004955513:2,933,918...2,976,931
JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 involved_in ISO (PMID:24698160)
(PMID:19513116)
BHF-UCL
MGI
PMID:19513116 PMID:24698160 NCBI chrNW_004955478:10,972,791...11,001,535
Ensembl chrNW_004955478:10,978,139...11,001,202
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 involved_in ISO (PMID:19513116) MGI PMID:19513116 NCBI chrNW_004955458:4,957,614...4,962,691
Ensembl chrNW_004955458:4,957,602...4,962,691
JBrowse link
G Tyms thymidylate synthetase involved_in ISO (PMID:15093541)
(PMID:22057276)
BHF-UCL
MGI
PMID:15093541 PMID:22057276 NCBI chrNW_004955402:9,295,862...9,304,952
Ensembl chrNW_004955402:9,296,321...9,306,631
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12321
    metabolic process 7441
      cellular metabolic process 6650
        one-carbon metabolic process 13
          serine-isocitrate lyase pathway 0
          tetrahydrofolate interconversion 10
paths to the root