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ONTOLOGY REPORT - ANNOTATIONS


Term:one-carbon metabolic process
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Accession:GO:0006730 term browser browse the term
Definition:The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.
Synonyms:exact_synonym: one carbon metabolism;   one-carbon transfer metabolic process;   one-carbon transfer metabolism
 alt_id: GO:0019753;   GO:0019754
 xref: UM-BBD_pathwayID:C1cyc


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one-carbon metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GNMT glycine N-methyltransferase acts_upstream_of_or_within ISO (MGI:3842675|PMID:17937387) MGI PMID:17937387 MGI:3842675 NCBI chr 6:42,550,631...42,554,385
Ensembl chr 6:43,846,560...43,849,679
JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:25633902) RGD
BHF-UCL
PMID:14597174 PMID:25633902 RGD:1302361 NCBI chr14:44,969,573...45,041,296
Ensembl chr14:63,223,484...63,293,881
JBrowse link
G SFXN1 sideroflexin 1 acts_upstream_of ISO (PMID:30442778) UniProt PMID:30442778 NCBI chr 5:170,825,507...170,876,741
Ensembl chr 5:177,738,961...177,775,212
JBrowse link
G SFXN3 sideroflexin 3 acts_upstream_of ISO (PMID:30442778) UniProt PMID:30442778 NCBI chr10:97,632,562...97,642,531
Ensembl chr10:101,109,287...101,116,396
JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 involved_in ISO (PMID:11516159), (PMID:29180469), (PMID:29364879), (PMID:29452640) UniProt PMID:11516159 PMID:29180469 PMID:29364879 PMID:29452640 NCBI chr12:31,692,451...31,697,727
Ensembl chr12:31,944,785...31,950,138
JBrowse link
tetrahydrofolate interconversion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DMGDH dimethylglycine dehydrogenase ISO RGD PMID:6163778 RGD:7245485 NCBI chr 5:36,241,341...36,313,995
Ensembl chr 5:36,732,005...36,805,883
JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:1881876)
(MGI:5503248|PMID:23704330)
BHF-UCL PMID:1881876 PMID:23704330 MGI:5503248 NCBI chr14:44,969,573...45,041,296
Ensembl chr14:63,223,484...63,293,881
JBrowse link
G MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like ISO RGD PMID:21163947 RGD:7244288 NCBI chr 4:49,889,607...50,034,860
Ensembl chr 4:55,722,237...55,867,117
JBrowse link
G MTHFR methylenetetrahydrofolate reductase involved_in ISO (PMID:10551815)
(PMID:12673793), (PMID:25736335)
BHF-UCL PMID:10551815 PMID:12673793 PMID:25736335 NCBI chr 1:10,548,196...10,568,174
Ensembl chr 1:11,766,334...11,785,419
JBrowse link
G SARDH sarcosine dehydrogenase ISO RGD PMID:6163778 RGD:7245485 NCBI chr 9:104,786,774...104,864,480
Ensembl chr 9:133,398,806...133,473,642
JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 involved_in ISO (PMID:24698160) BHF-UCL PMID:24698160 NCBI chr17:32,870,949...32,905,690
Ensembl chr17:37,849,206...37,884,220
JBrowse link
G TYMS thymidylate synthetase involved_in ISO (PMID:15093541) BHF-UCL PMID:15093541 NCBI chr18:13,653,085...13,668,478
Ensembl chr18:17,295,182...17,310,320
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12614
    metabolic process 7907
      cellular metabolic process 7246
        one-carbon metabolic process 11
          serine-isocitrate lyase pathway 0
          tetrahydrofolate interconversion 7
paths to the root