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ONTOLOGY REPORT - ANNOTATIONS

Term:cholesterol catabolic process
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Accession:GO:0006707 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
Synonyms:exact_synonym: cholesterol breakdown;   cholesterol catabolism;   cholesterol degradation


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cholesterol catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1d1 aldo-keto reductase family 1, member D1 involved_in ISO
IEA		 (PMID:7508385)
GO_REF:0000107		 RGD
Ensembl		 PMID:7508385 GO_REF:0000107 NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372 		JBrowse link
G Apoe apolipoprotein E involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:1314982|PMID:9826706)		 RGD PMID:9826706 PMID:21873635 MGI:1314982, RGD:13792537 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:9660774)
GO_REF:0000041
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:9660774 GO_REF:0000024 GO_REF:0000041 GO_REF:0000107 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551 		JBrowse link
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 acts_upstream_of_or_within ISO (MGI:1859119|PMID:10748047) RGD PMID:10748047 MGI:1859119 NCBI chr 9:17,230,455...17,306,775
Ensembl chr 9:17,230,455...17,306,775 		JBrowse link
G Cyp46a1 cytochrome P450, family 46, subfamily a, polypeptide 1 involved_in IBA
ISO		 PMID:21873635
(PMID:14640697), (PMID:18621681), (PMID:25017465)
(MGI:1339884|PMID:10377398), (MGI:6393037|PMID:20193040)		 RGD PMID:10377398 PMID:14640697 PMID:18621681 PMID:20193040 PMID:25017465 More... MGI:1339884 MGI:6393037, RGD:13792537 NCBI chr 6:127,247,543...127,274,765
Ensembl chr 6:127,243,315...127,274,760 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 involved_in
acts_upstream_of_or_within		 IDA
IEA
ISO		 PMID:1694852
GO_REF:0000041
(MGI:1933035|PMID:11279518), (MGI:3603484|PMID:15845870)		 UniProt
RGD		 PMID:11279518 PMID:15845870 PMID:1694852 GO_REF:0000041 MGI:1933035 MGI:3603484, RGD:70534 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 IDA RGD PMID:16081591 RGD:1599972 NCBI chr 1:182,412,216...182,415,447
Ensembl chr 1:182,412,151...182,415,442 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1928989 (MGI:1934548|PMID:11278646), (MGI:3690692|PMID:10559220)
GO_REF:0000107		 RGD
Ensembl		 PMID:10559220 PMID:11278646 GO_REF:0000107 MGI:1934548 MGI:3690692 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19574
    metabolic process 11556
      small molecule metabolic process 1915
        alcohol metabolic process 374
          alcohol catabolic process 38
            cholesterol catabolic process 8
Path 2
Term Annotations click to browse term
  biological_process 19574
    metabolic process 11556
      primary metabolic process 9996
        lipid metabolic process 1406
          steroid metabolic process 349
            sterol metabolic process 157
              cholesterol metabolic process 146
                cholesterol catabolic process 8
paths to the root