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Term:cholesterol catabolic process
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Accession:GO:0006707 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
Synonyms:exact_synonym: cholesterol breakdown;   cholesterol catabolism;   cholesterol degradation

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cholesterol catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKR1D1 aldo-keto reductase family 1 member D1 JBrowse link 7 130,023,017 130,076,397 RGD:9068941
G APOE apolipoprotein E JBrowse link 19 41,853,669 41,857,252 RGD:9068941
G CEL carboxyl ester lipase JBrowse link 9 104,180,310 104,191,434 RGD:9068941
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 JBrowse link 2B 106,042,235 106,076,840 RGD:9068941
G CYP39A1 cytochrome P450 family 39 subfamily A member 1 JBrowse link 6 46,132,584 46,235,578 RGD:9068941
G CYP46A1 cytochrome P450 family 46 subfamily A member 1 JBrowse link 14 80,309,698 80,352,181 RGD:9068941
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 JBrowse link 8 54,942,509 54,952,500 RGD:9068941
G HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 JBrowse link 16 23,979,487 23,984,225 RGD:9068941
G MT3 metallothionein 3 JBrowse link 16 36,875,919 36,877,558 RGD:9068941
G SCARB1 scavenger receptor class B member 1 JBrowse link 12 122,293,803 122,455,314 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12489
    metabolic process 7937
      small molecule metabolic process 1306
        alcohol metabolic process 262
          alcohol catabolic process 36
            cholesterol catabolic process 10
Path 2
Term Annotations click to browse term
  biological_process 12489
    metabolic process 7937
      primary metabolic process 7011
        lipid metabolic process 971
          steroid metabolic process 238
            sterol metabolic process 102
              cholesterol metabolic process 101
                cholesterol catabolic process 10
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.