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ONTOLOGY REPORT - ANNOTATIONS


Term:steroid catabolic process
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Accession:GO:0006706 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
Synonyms:exact_synonym: steroid breakdown;   steroid catabolism;   steroid degradation



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steroid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBR1 carbonyl reductase 1 ISO RGD PMID:7705364 RGD:69801 NCBI chr21:22,440,726...22,443,950
Ensembl chr21:35,800,177...35,803,458
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 involved_in ISO (PMID:18356043) BHF-UCL PMID:18356043 NCBI chr15:53,692,877...53,699,279
Ensembl chr15:73,311,720...73,319,447
JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 involved_in ISO (PMID:18356043) BHF-UCL PMID:18356043 NCBI chr 7:91,797,037...91,824,696
Ensembl chr 7:105,230,666...105,258,401
JBrowse link
G HSD17B14 hydroxysteroid 17-beta dehydrogenase 14 involved_in ISO (PMID:17067289) HGNC-UCL PMID:17067289 NCBI chr19:45,812,558...45,837,292
Ensembl chr19:54,918,606...54,942,676
JBrowse link
G SRD5A2 steroid 5 alpha-reductase 2 ISO RGD PMID:1527072 RGD:729939 NCBI chr2A:31,542,646...31,597,394
Ensembl chr2A:31,610,487...31,665,718
JBrowse link
androgen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 involved_in ISO (PMID:26482249) CAFA PMID:26482249 NCBI chr15:30,152,924...30,282,854
Ensembl chr15:48,486,688...48,521,554
JBrowse link
G HSD17B11 hydroxysteroid 17-beta dehydrogenase 11 involved_in ISO (PMID:12697717) HGNC-UCL PMID:12697717 NCBI chr 4:79,638,500...79,687,204
Ensembl chr 4:90,364,769...90,413,522
JBrowse link
G SPP1 secreted phosphoprotein 1 involved_in ISO (PMID:26482249) CAFA PMID:26482249 NCBI chr 4:80,263,711...80,271,466
Ensembl chr 4:90,988,200...90,995,935
JBrowse link
G SRD5A1 steroid 5 alpha-reductase 1 ISO RGD PMID:2339109 RGD:70289 NCBI chr 5:6,953,795...6,996,010
Ensembl chr 5:6,629,093...6,664,264
JBrowse link
brexanolone catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSD17B6 hydroxysteroid 17-beta dehydrogenase 6 involved_in ISO (PMID:10896656), (PMID:11360992) UniProt PMID:10896656 PMID:11360992 NCBI chr12:32,117,696...32,155,740
Ensembl chr12:32,371,489...32,408,860
JBrowse link
cholesterol catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1D1 aldo-keto reductase family 1 member D1 involved_in ISO (PMID:7508385) UniProt PMID:7508385 NCBI chr 7:130,023,017...130,076,397
Ensembl chr 7:142,525,467...142,571,331
JBrowse link
G APOE apolipoprotein E acts_upstream_of_or_within ISO (MGI:1314982|PMID:9826706) MGI PMID:9826706 MGI:1314982 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490
JBrowse link
G CEL carboxyl ester lipase involved_in ISO (PMID:12031288) UniProt PMID:12031288 NCBI chr 9:104,180,310...104,191,434
Ensembl chr 9:132,810,986...132,821,010
JBrowse link
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 involved_in ISO (PMID:9660774) UniProt PMID:9660774 NCBI chr2B:106,042,235...106,076,840
Ensembl chr2B:224,637,238...224,671,474
JBrowse link
G CYP39A1 cytochrome P450 family 39 subfamily A member 1 acts_upstream_of_or_within ISO (MGI:1859119|PMID:10748047) MGI PMID:10748047 MGI:1859119 NCBI chr 6:46,132,584...46,235,578
Ensembl chr 6:47,404,969...47,507,600
JBrowse link
G CYP46A1 cytochrome P450 family 46 subfamily A member 1 involved_in ISO (PMID:14640697), (PMID:18621681), (PMID:25017465)
(MGI:1339884|PMID:10377398), (MGI:6393037|PMID:20193040)
UniProt PMID:10377398 PMID:14640697 PMID:18621681 PMID:20193040 PMID:25017465 MGI:1339884 MGI:6393037 NCBI chr14:80,309,698...80,352,181
Ensembl chr14:99,628,511...99,671,218
JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in
acts_upstream_of_or_within
ISO PMID:1694852
(MGI:1933035|PMID:11279518), (MGI:3603484|PMID:15845870)
UniProt
MGI
PMID:1694852 PMID:11279518 PMID:15845870 MGI:1933035 MGI:3603484 RGD:70534 NCBI chr 8:54,942,509...54,952,500
Ensembl chr 8:56,593,799...56,604,037
JBrowse link
G HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 ISO RGD PMID:16081591 RGD:1599972 NCBI chr16:23,979,487...23,984,225
Ensembl chr16:31,352,322...31,356,803
JBrowse link
G MT3 metallothionein 3 involved_in ISO (MGI:4881636|PMID:20544854) UniProt PMID:20544854 MGI:4881636 NCBI chr16:36,875,919...36,877,558
Ensembl chr16:56,007,922...56,028,093
JBrowse link
G SCARB1 scavenger receptor class B member 1 acts_upstream_of_or_within ISO (MGI:1934548|PMID:11278646)
(MGI:3690692|PMID:10559220)
MGI PMID:10559220 PMID:11278646 MGI:1934548 MGI:3690692 NCBI chr12:122,293,803...122,455,314
Ensembl chr12:126,659,532...126,694,767
JBrowse link
estrogen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SULT1E1 sulfotransferase family 1E member 1 involved_in ISO (PMID:23207770) CAFA PMID:23207770 NCBI chr 4:54,377,681...54,396,619 JBrowse link
glucocorticoid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 ISO RGD PMID:12460758 RGD:1625060 NCBI chr 1:185,262,599...185,311,417
Ensembl chr 1:190,086,449...190,116,765
JBrowse link
G YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta involved_in ISO (PMID:15790729) UniProt PMID:15790729 NCBI chr22:12,966,653...12,979,695
Ensembl chr22:30,819,821...30,831,804
JBrowse link
vitamin D catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 involved_in ISO PMID:10231362
PMID:16617161
(PMID:16617161), (PMID:24893882), (PMID:29461981), (PMID:8506296), (PMID:8679605)
UniProt PMID:8506296 PMID:8679605 PMID:10231362 PMID:16617161 PMID:24893882 More... RGD:14995311 RGD:14995316 NCBI chr20:50,500,103...50,520,487
Ensembl chr20:51,721,685...51,742,716
JBrowse link
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 involved_in ISO PMID:9333115
(MGI:1097206|PMID:9295274)
BHF-UCL PMID:9295274 PMID:9333115 MGI:1097206 RGD:69373 NCBI chr12:31,158,814...31,164,462
Ensembl chr12:31,419,773...31,424,822
JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 involved_in ISO (PMID:29461981) UniProt PMID:29461981 NCBI chr 7:91,797,037...91,824,696
Ensembl chr 7:105,230,666...105,258,401
JBrowse link
G FGF23 fibroblast growth factor 23 involved_in ISO (PMID:15040831) UniProt PMID:15040831 NCBI chr12:4,479,116...4,488,797
Ensembl chr12:4,400,802...4,412,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12786
    metabolic process 8099
      primary metabolic process 7110
        lipid metabolic process 1027
          steroid metabolic process 247
            steroid catabolic process 26
              (17Z)-protosta-17(20),24-dien-3beta-ol catabolic process 0
              C21-steroid hormone catabolic process + 0
              androgen catabolic process 4
              brexanolone catabolic process 1
              ecdysteroid catabolic process + 0
              ergosteryl 3-beta-D-glucoside catabolic process 0
              estrogen catabolic process 1
              glucocorticoid catabolic process + 2
              helvolic acid catabolic process 0
              mineralocorticoid catabolic process + 0
              phytosteroid catabolic process + 0
              sterol catabolic process + 10
              vitamin D catabolic process + 4
paths to the root