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ONTOLOGY REPORT - ANNOTATIONS


Term:steroid catabolic process
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Accession:GO:0006706 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
Synonyms:exact_synonym: steroid breakdown;   steroid catabolism;   steroid degradation



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steroid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbr1 carbonyl reductase 1 IDA RGD PMID:7705364 RGD:69801 NCBI chr11:32,860,618...32,862,981
Ensembl chr11:32,857,991...32,895,275
Ensembl chr11:32,857,991...32,895,275
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 involved_in ISO (PMID:18356043) RGD PMID:18356043 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 TAS RGD PMID:12909643 RGD:1600873 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 involved_in ISO (PMID:18356043) RGD PMID:18356043 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
JBrowse link
G Hsd17b14 hydroxysteroid (17-beta) dehydrogenase 14 involved_in ISO
IBA
(PMID:17067289)
PMID:21873635
RGD PMID:17067289 PMID:21873635 RGD:13792537 NCBI chr 1:96,029,290...96,039,088
Ensembl chr 1:96,029,284...96,039,883
JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 IDA RGD PMID:1527072 RGD:729939 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112
JBrowse link
androgen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 involved_in ISO (PMID:26482249) RGD PMID:26482249 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 involved_in ISO (PMID:12697717) RGD PMID:12697717 NCBI chr14:5,693,304...5,743,157
Ensembl chr14:5,711,964...5,743,161
JBrowse link
G Spp1 secreted phosphoprotein 1 involved_in ISO (PMID:26482249) RGD PMID:26482249 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IDA RGD PMID:2339109 RGD:70289 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461
JBrowse link
brexanolone catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 involved_in ISO
ISS
(PMID:10896656), (PMID:11360992)
GO_REF:0000024
RGD
UniProt
PMID:10896656 PMID:11360992 GO_REF:0000024 NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425
JBrowse link
cholesterol catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1d1 aldo-keto reductase family 1, member D1 involved_in ISO (PMID:7508385) RGD PMID:7508385 NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372
JBrowse link
G Apoe apolipoprotein E involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:1314982|PMID:9826706)
RGD PMID:9826706 PMID:21873635 MGI:1314982, RGD:13792537 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Cel carboxyl ester lipase involved_in ISO (PMID:12031288) RGD PMID:12031288 NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
GO_REF:0000041
(PMID:9660774)
UniProt
Ensembl
RGD
PMID:9660774 GO_REF:0000024 GO_REF:0000041 GO_REF:0000107 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 acts_upstream_of_or_within ISO (MGI:1859119|PMID:10748047) RGD PMID:10748047 MGI:1859119 NCBI chr 9:17,230,455...17,306,775
Ensembl chr 9:17,230,455...17,306,775
JBrowse link
G Cyp46a1 cytochrome P450, family 46, subfamily a, polypeptide 1 involved_in IBA
ISO
PMID:21873635
(MGI:1339884|PMID:10377398), (MGI:6393037|PMID:20193040)
(PMID:14640697), (PMID:18621681), (PMID:25017465)
RGD PMID:10377398 PMID:14640697 PMID:18621681 PMID:20193040 PMID:25017465 More... MGI:1339884 MGI:6393037, RGD:13792537 NCBI chr 6:127,243,315...127,274,765
Ensembl chr 6:127,243,315...127,274,760
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 involved_in
acts_upstream_of_or_within
IDA
ISO
IEA
PMID:1694852
(MGI:1933035|PMID:11279518), (MGI:3603484|PMID:15845870)
GO_REF:0000041
RGD
UniProt
PMID:11279518 PMID:15845870 PMID:1694852 GO_REF:0000041 MGI:1933035 MGI:3603484, RGD:70534 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 IDA RGD PMID:16081591 RGD:1599972 NCBI chr 1:182,411,836...182,415,447
Ensembl chr 1:182,412,151...182,415,442
JBrowse link
G Mt3 metallothionein 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:4881636|PMID:20544854)
UniProt
RGD
PMID:20544854 GO_REF:0000024 MGI:4881636 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158
JBrowse link
G Scarb1 scavenger receptor class B, member 1 acts_upstream_of_or_within ISO MGI:1928989 (MGI:1934548|PMID:11278646), (MGI:3690692|PMID:10559220) RGD PMID:10559220 PMID:11278646 MGI:1934548 MGI:3690692 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
estrogen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sult1e1 sulfotransferase family 1E member 1 involved_in ISO (PMID:23207770) RGD PMID:23207770 NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275
JBrowse link
G Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C IDA RGD PMID:15502008 RGD:2317077 NCBI chr 9:88,739,577...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
glucocorticoid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 IDA RGD PMID:12460758 RGD:1625060 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
JBrowse link
G Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta involved_in ISO
IEA
(PMID:15790729)
GO_REF:0000107
RGD
Ensembl
PMID:15790729 GO_REF:0000107 NCBI chr14:77,696,332...77,705,715
Ensembl chr14:77,696,333...77,705,741
JBrowse link
progesterone catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 acts_upstream_of_or_within ISO MGI:3527218 (MGI:3526508|PMID:15471942) RGD PMID:15471942 MGI:3526508 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
vitamin D catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 involved_in TAS
IBA
IDA
ISO
PMID:21873635
PMID:16617161
(PMID:16617161), (PMID:24893882), (PMID:29461981), (PMID:8506296), (PMID:8679605)
PMID:10231362
RGD PMID:8506296 PMID:8679605 PMID:16617161 PMID:24893882 PMID:29461981 More... RGD:625496, RGD:13792537, RGD:14995311, RGD:14995316 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 involved_in IBA
IDA
IEA
ISO
PMID:21873635
PMID:9333115
GO_REF:0000107
(MGI:1097206|PMID:9295274)
Ensembl
RGD
PMID:9295274 PMID:21873635 PMID:9333115 GO_REF:0000107 MGI:1097206, RGD:13792537, RGD:69373 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 involved_in ISO (PMID:29461981) RGD PMID:29461981 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Fgf23 fibroblast growth factor 23 involved_in ISO (PMID:15040831) RGD PMID:15040831 NCBI chr 4:159,914,393...159,922,073
Ensembl chr 4:159,914,272...159,923,821
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20091
    metabolic process 12359
      primary metabolic process 11118
        lipid metabolic process 1454
          steroid metabolic process 344
            steroid catabolic process 28
              (17Z)-protosta-17(20),24-dien-3beta-ol catabolic process 0
              C21-steroid hormone catabolic process + 1
              androgen catabolic process 4
              brexanolone catabolic process 1
              ecdysteroid catabolic process + 0
              ergosteryl 3-beta-D-glucoside catabolic process 0
              estrogen catabolic process 2
              glucocorticoid catabolic process + 2
              helvolic acid catabolic process 0
              mineralocorticoid catabolic process + 0
              phytosteroid catabolic process + 0
              sterol catabolic process + 10
              vitamin D catabolic process + 4
paths to the root