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ONTOLOGY REPORT - ANNOTATIONS


Term:steroid catabolic process
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Accession:GO:0006706 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
Synonyms:exact_synonym: steroid breakdown;   steroid catabolism;   steroid degradation


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steroid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbr1 carbonyl reductase 1 IDA RGD PMID:7705364 RGD:69801 NCBI chr11:33,813,041...33,815,418
Ensembl chr11:33,845,463...33,847,793
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 involved_in ISO (PMID:18356043) RGD PMID:18356043 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 TAS RGD PMID:12909643 RGD:1600873 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603
JBrowse link
G Hsd17b14 hydroxysteroid (17-beta) dehydrogenase 14 involved_in ISO (PMID:17067289) RGD PMID:17067289 NCBI chr 1:101,541,266...101,551,059
Ensembl chr 1:101,541,266...101,551,059
JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 IDA RGD PMID:1527072 RGD:729939 NCBI chr 6:25,279,635...25,315,501
Ensembl chr 6:25,279,626...25,315,511
JBrowse link
androgen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:26482249)
Ensembl
RGD
PMID:26482249 GO_REF:0000107 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 involved_in ISO (PMID:12697717) RGD PMID:12697717 NCBI chr14:7,054,724...7,104,567
Ensembl chr14:7,073,445...7,104,566
JBrowse link
G Spp1 secreted phosphoprotein 1 involved_in ISO (PMID:26482249) RGD PMID:26482249 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IDA RGD PMID:2339109 RGD:70289 NCBI chr 1:36,320,504...36,354,694
Ensembl chr 1:36,320,461...36,354,756
JBrowse link
brexanolone catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 involved_in ISO
ISS
(PMID:10896656), (PMID:11360992)
GO_REF:0000024
RGD
UniProt
PMID:10896656 PMID:11360992 GO_REF:0000024 NCBI chr 7:2,412,370...2,431,249
Ensembl chr 7:2,412,363...2,431,197
Ensembl chr13:2,412,363...2,431,197
JBrowse link
cholesterol catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1d1 aldo-keto reductase family 1, member D1 involved_in ISO
IEA
(PMID:7508385)
GO_REF:0000107
RGD
Ensembl
PMID:7508385 GO_REF:0000107 NCBI chr 4:65,110,706...65,143,930
Ensembl chr 4:65,110,746...65,143,941
JBrowse link
G Apoe apolipoprotein E involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:1314982|PMID:9826706)
RGD PMID:9826706, PMID:21873635 MGI:1314982, RGD:13792537 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Cel carboxyl ester lipase involved_in ISO
IEA
(PMID:12031288)
GO_REF:0000107
RGD
Ensembl
PMID:12031288 GO_REF:0000107 NCBI chr 3:7,134,021...7,141,522
Ensembl chr 3:7,134,021...7,141,522
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
GO_REF:0000041
(PMID:9660774)
UniProt
Ensembl
RGD
PMID:9660774 GO_REF:0000024 GO_REF:0000041 GO_REF:0000107 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
JBrowse link
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 acts_upstream_of_or_within ISO (MGI:1859119|PMID:10748047) RGD PMID:10748047 MGI:1859119 NCBI chr 9:19,804,079...19,880,346
Ensembl chr 9:19,804,079...19,880,346
JBrowse link
G Cyp46a1 cytochrome P450, family 46, subfamily a, polypeptide 1 involved_in IBA
ISO
PMID:21873635
(MGI:1339884|PMID:10377398), (MGI:6393037|PMID:20193040)
(PMID:14640697), (PMID:18621681), (PMID:25017465)
RGD PMID:10377398 PMID:14640697 PMID:18621681 PMID:20193040 PMID:25017465, PMID:21873635 MGI:1339884 MGI:6393037, RGD:13792537 NCBI chr 6:132,242,328...132,273,788
Ensembl chr 6:132,242,328...132,273,787
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 involved_in
acts_upstream_of_or_within
IDA
ISO
IEA
PMID:1694852
(MGI:1933035|PMID:11279518), (MGI:3603484|PMID:15845870)
GO_REF:0000041
RGD
UniProt
PMID:11279518 PMID:15845870, PMID:1694852 GO_REF:0000041 MGI:1933035 MGI:3603484, RGD:70534 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 IDA RGD PMID:16081591 RGD:1599972 NCBI chr 1:199,248,084...199,251,745
Ensembl chr 1:199,248,470...199,251,740
JBrowse link
G Mt3 metallothionein 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:4881636|PMID:20544854)
UniProt
RGD
PMID:20544854 GO_REF:0000024 MGI:4881636 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
G Scarb1 scavenger receptor class B, member 1 acts_upstream_of_or_within ISO MGI:1928989 (MGI:1934548|PMID:11278646), (MGI:3690692|PMID:10559220) RGD PMID:10559220 PMID:11278646 MGI:1934548 MGI:3690692 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
estrogen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sult1e1 sulfotransferase family 1E member 1 involved_in ISO (PMID:23207770) RGD PMID:23207770 NCBI chr14:22,070,861...22,089,264
Ensembl chr14:22,072,024...22,089,248
JBrowse link
G Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C IDA RGD PMID:15502008 RGD:2317077 NCBI chr 9:95,233,957...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
glucocorticoid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 IDA RGD PMID:12460758 RGD:1625060 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603
JBrowse link
G Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta involved_in ISO
IEA
(PMID:15790729)
GO_REF:0000107
RGD
Ensembl
PMID:15790729 GO_REF:0000107 NCBI chr14:83,053,041...83,062,424
Ensembl chr14:83,053,041...83,062,424
JBrowse link
progesterone catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 acts_upstream_of_or_within ISO MGI:3527218 (MGI:3526508|PMID:15471942) RGD PMID:15471942 MGI:3526508 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
vitamin D catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 involved_in TAS
IBA
IDA
ISO
PMID:21873635
PMID:16617161
(PMID:16617161), (PMID:24893882), (PMID:29461981), (PMID:8506296), (PMID:8679605)
PMID:10231362
RGD PMID:8506296 PMID:8679605 PMID:16617161 PMID:24893882 PMID:29461981, PMID:12048211, PMID:21873635, PMID:16617161, PMID:10231362 RGD:625496, RGD:13792537, RGD:14995311, RGD:14995316 NCBI chr 3:168,097,484...168,111,920
Ensembl chr 3:168,097,485...168,111,920
JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 involved_in IBA
ISO
IDA
PMID:21873635
(MGI:1097206|PMID:9295274)
PMID:9333115
RGD PMID:9295274, PMID:21873635, PMID:9333115 MGI:1097206, RGD:13792537, RGD:69373 NCBI chr 7:70,333,150...70,340,006
Ensembl chr 7:70,335,061...70,340,005
JBrowse link
G Fgf23 fibroblast growth factor 23 involved_in ISO (PMID:15040831) RGD PMID:15040831 NCBI chr 4:159,622,404...159,630,082
Ensembl chr 4:159,622,404...159,630,082
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    metabolic process 11797
      primary metabolic process 10565
        lipid metabolic process 1362
          steroid metabolic process 333
            steroid catabolic process 27
              (17Z)-protosta-17(20),24-dien-3beta-ol catabolic process 0
              C21-steroid hormone catabolic process + 1
              androgen catabolic process 4
              brexanolone catabolic process 1
              ecdysteroid catabolic process + 0
              ergosteryl 3-beta-D-glucoside catabolic process 0
              estrogen catabolic process 2
              glucocorticoid catabolic process + 2
              helvolic acid catabolic process 0
              mineralocorticoid catabolic process + 0
              phytosteroid catabolic process + 0
              sterol catabolic process + 10
              vitamin D catabolic process + 3
paths to the root