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ONTOLOGY REPORT - ANNOTATIONS


Term:mineralocorticoid biosynthetic process
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Accession:GO:0006705 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
Synonyms:exact_synonym: mineralocorticoid anabolism;   mineralocorticoid biosynthesis;   mineralocorticoid formation;   mineralocorticoid synthesis



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aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1H calcium voltage-gated channel subunit alpha1 H involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:40,637,420...40,694,616
Ensembl chr 3:40,637,436...40,694,818
JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:50073|PMID:1686470), (MGI:80407|PMID:8645611)
GO_Central
MGI
PMID:1686470 PMID:8645611 PMID:21873635 MGI:50073 MGI:80407 NCBI chr 4:1,365,725...1,373,138 JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:15,750,487...15,762,982
Ensembl chr17:15,749,835...15,761,215
JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:25,344,924...25,468,430
Ensembl chr 7:25,344,822...25,470,470
JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) UniProt PMID:16981135 NCBI chr 2:47,385,244...47,444,664
Ensembl chr 2:47,385,191...47,446,538
JBrowse link
G LOC100621006 RE1-silencing transcription factor-like involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 8:56,048,280...56,215,011
Ensembl chr 8:56,035,150...56,215,013
JBrowse link
G REST RE1 silencing transcription factor involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 8:56,035,182...56,061,140
Ensembl chr 8:56,035,150...56,215,013
JBrowse link
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:5,058,817...5,208,868
Ensembl chr 7:5,058,817...5,211,316
JBrowse link
G DAB2 DAB adaptor protein 2 ISO RGD PMID:17303656 RGD:7243836 NCBI chr16:24,590,638...24,776,937
Ensembl chr16:24,514,722...24,776,903
JBrowse link
G WNT4 Wnt family member 4 involved_in ISO (PMID:16981135) UniProt PMID:16981135 NCBI chr 6:80,110,238...80,138,165 JBrowse link
regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLCN2 chloride voltage-gated channel 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:122,234,731...122,249,889
Ensembl chr13:122,234,736...122,249,867
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16673
    cellular process 15967
      cellular metabolic process 9547
        cellular hormone metabolic process 116
          mineralocorticoid metabolic process 15
            mineralocorticoid biosynthetic process 11
              aldosterone biosynthetic process + 11
Path 2
Term Annotations click to browse term
  biological_process 16673
    metabolic process 10521
      organic substance metabolic process 10083
        organic substance biosynthetic process 5257
          lipid biosynthetic process 609
            steroid biosynthetic process 149
              steroid hormone biosynthetic process 32
                mineralocorticoid biosynthetic process 11
                  aldosterone biosynthetic process + 11
paths to the root