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ONTOLOGY REPORT - ANNOTATIONS


Term:mineralocorticoid biosynthetic process
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Accession:GO:0006705 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
Synonyms:exact_synonym: mineralocorticoid anabolism;   mineralocorticoid biosynthesis;   mineralocorticoid formation;   mineralocorticoid synthesis



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aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1H calcium voltage-gated channel subunit alpha1 H involved_in ISO PMID:19342457
(PMID:19342457)
UniProt PMID:19342457 RGD:4891166 Ensembl chr16:1,195,364...1,222,917 JBrowse link
G CYP11B1 cytochrome P450 family 11 subfamily B member 1 involved_in ISO (PMID:19342457)
(PMID:2256920)
UniProt
BHF-UCL
PMID:2256920 PMID:19342457 NCBI chr 8:139,584,976...139,592,466
Ensembl chr 8:142,629,127...142,634,654
JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610
JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chr 6:55,302,721...55,425,248
Ensembl chr 6:56,936,850...57,059,519
JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) UniProt PMID:16981135 NCBI chr11:12,131,306...12,177,906
Ensembl chr11:11,824,955...11,871,139
JBrowse link
G REST RE1 silencing transcription factor involved_in ISO (PMID:19342457) UniProt PMID:19342457 RGD:4891166 NCBI chr 4:66,984,466...67,012,301
Ensembl chr 4:73,526,085...73,582,242
JBrowse link
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP6 bone morphogenetic protein 6 involved_in ISO (PMID:16527843) UniProt PMID:16527843 NCBI chr 6:7,564,164...7,720,341
Ensembl chr 6:7,848,249...8,000,649
JBrowse link
G DAB2 DAB adaptor protein 2 ISO RGD PMID:17303656 RGD:7243836 NCBI chr 5:70,951,198...71,004,836
Ensembl chr 5:76,022,143...76,041,443
JBrowse link
G WNT4 Wnt family member 4 involved_in ISO (PMID:16981135) UniProt PMID:16981135 NCBI chr 1:21,310,228...21,335,985
Ensembl chr 1:22,255,056...22,268,801
JBrowse link
regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLCN2 chloride voltage-gated channel 2 involved_in ISO (PMID:29403011) UniProt PMID:29403011 NCBI chr 3:181,383,608...181,399,200
Ensembl chr 3:189,862,489...189,881,049
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12786
    cellular process 11938
      cellular metabolic process 7388
        cellular hormone metabolic process 95
          mineralocorticoid metabolic process 14
            mineralocorticoid biosynthetic process 10
              aldosterone biosynthetic process + 10
Path 2
Term Annotations click to browse term
  biological_process 12786
    metabolic process 8099
      organic substance metabolic process 7799
        organic substance biosynthetic process 4060
          lipid biosynthetic process 505
            steroid biosynthetic process 123
              steroid hormone biosynthetic process 28
                mineralocorticoid biosynthetic process 10
                  aldosterone biosynthetic process + 10
paths to the root