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ONTOLOGY REPORT - ANNOTATIONS


Term:estrogen biosynthetic process
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Accession:GO:0006703 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants.
Synonyms:exact_synonym: estrogen anabolism;   estrogen biosynthesis;   estrogen formation;   estrogen synthesis;   oestrogen biosynthesis;   oestrogen biosynthetic process


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estrogen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 IDA estrone RGD PMID:19665544 RGD:4891164 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 involved_in IDA
ISO
IEA
estradiol
(MGI:1267145|PMID:9658408)
GO_REF:0000041
(PMID:8994190)
RGD
UniProt
PMID:8994190 PMID:9658408, PMID:8612487 GO_REF:0000041 MGI:1267145, RGD:728619 NCBI chr10:88,987,558...88,989,758
Ensembl chr10:88,987,558...88,989,757
JBrowse link
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 3:82,924,699...83,048,465
Ensembl chr 3:82,924,687...83,048,435
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 IDA estrone RGD PMID:8612487 RGD:728619 NCBI chr19:50,246,404...50,317,892
Ensembl chr19:50,246,402...50,317,891
JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 involved_in IDA
ISO
IEA
PMID:9658408
(MGI:1267145|PMID:9658408), (MGI:2662631|PMID:12732193)
(PMID:12732193)
GO_REF:0000107
GO_REF:0000041
RGD
Ensembl
UniProt
PMID:9658408 PMID:12732193, PMID:9658408 GO_REF:0000041 GO_REF:0000107 MGI:1267145 MGI:2662631, RGD:30309934 NCBI chr13:88,288,116...88,308,019
Ensembl chr13:88,288,046...88,307,988
JBrowse link
G Hsd17b8 hydroxysteroid (17-beta) dehydrogenase 8 involved_in IBA
IEA
ISS
ISO
PMID:21873635
GO_REF:0000041
GO_REF:0000024
(PMID:17978863)
UniProt
RGD
PMID:17978863, PMID:21873635 GO_REF:0000024 GO_REF:0000041, RGD:13792537 NCBI chr20:3,817,212...3,819,316
Ensembl chr20:3,817,179...3,819,235
JBrowse link
G Rdh8 retinol dehydrogenase 8 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:21,835,065...21,842,374
Ensembl chr 8:21,835,103...21,842,374
JBrowse link
G Star steroidogenic acute regulatory protein IMP estradiol; positive regulation RGD PMID:16579833 RGD:1600078 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19599
    cellular process 18451
      cellular metabolic process 10814
        cellular biosynthetic process 5984
          estrogen biosynthetic process 8
            negative regulation of estrogen biosynthetic process 0
            positive regulation of estrogen biosynthetic process 0
            regulation of estrogen biosynthetic process + 0
Path 2
Term Annotations click to browse term
  biological_process 19599
    metabolic process 11860
      primary metabolic process 10618
        lipid metabolic process 1360
          lipid biosynthetic process 652
            steroid biosynthetic process 168
              steroid hormone biosynthetic process 38
                estrogen biosynthetic process 8
                  negative regulation of estrogen biosynthetic process 0
                  positive regulation of estrogen biosynthetic process 0
                  regulation of estrogen biosynthetic process + 0
paths to the root