Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:C21-steroid hormone biosynthetic process
go back to main search page
Accession:GO:0006700 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones.
Synonyms:exact_synonym: C21-steroid hormone anabolism;   C21-steroid hormone biosynthesis;   C21-steroid hormone formation;   C21-steroid hormone synthesis


show annotations for term's descendants           Sort by:
 
C21-steroid hormone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101975820 cholesterol side-chain cleavage enzyme, mitochondrial acts_upstream_of_or_within
involved_in
ISO pregnenolone
(MGI:68080|PMID:7527351)
(PMID:11502818), (PMID:18182448), (PMID:21636783)
RGD
MGI
UniProt
PMID:7527351 PMID:11502818 PMID:18182448 PMID:19665544 PMID:21636783 MGI:68080 RGD:4891164 NCBI chrNW_004936471:33,367,810...33,380,764 JBrowse link
aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1h calcium voltage-gated channel subunit alpha1 H involved_in ISO (PMID:19342457) UniProt PMID:19342457 RGD:4891166 NCBI chrNW_004936694:2,702,224...2,724,574 JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chrNW_004936485:12,428,765...12,439,570 JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chrNW_004936476:5,350,870...5,464,561 JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) UniProt PMID:16981135 NCBI chrNW_004936528:6,428,824...6,477,007 JBrowse link
G Rest RE1 silencing transcription factor involved_in ISO (PMID:19342457) UniProt PMID:19342457 RGD:4891166 NCBI chrNW_004936482:19,018,454...19,040,438 JBrowse link
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp6 bone morphogenetic protein 6 involved_in ISO (PMID:16527843) UniProt PMID:16527843 NCBI chrNW_004936534:4,707,658...4,871,865 JBrowse link
G Dab2 DAB adaptor protein 2 ISO RGD PMID:17303656 RGD:7243836 NCBI chrNW_004936518:2,915,819...2,936,474 JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO (PMID:16981135) UniProt PMID:16981135 NCBI chrNW_004936474:7,623,462...7,635,416 JBrowse link
positive regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppargc1a PPARG coactivator 1 alpha ISO RGD PMID:20133449 RGD:10059648 NCBI chrNW_004936477:4,881,230...5,488,208 JBrowse link
progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scp2 sterol carrier protein 2 involved_in ISO (PMID:1703300) UniProt PMID:1703300 NCBI chrNW_004936522:8,004,503...8,110,995 JBrowse link
G Stard3 StAR related lipid transfer domain containing 3 acts_upstream_of_or_within ISO (MGI:3039987|PMID:14963026) MGI PMID:14963026 MGI:3039987 NCBI chrNW_004936490:14,832,067...14,856,330 JBrowse link
regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcn2 chloride voltage-gated channel 2 involved_in ISO (PMID:29403011) UniProt PMID:29403011 NCBI chrNW_004936578:5,525,461...5,539,351 JBrowse link
regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgkq diacylglycerol kinase theta involved_in ISO (PMID:24369117) ParkinsonsUK-UCL PMID:24369117 NCBI chrNW_004936477:22,225,624...22,238,825 JBrowse link
G Egr1 early growth response 1 involved_in ISO (MGI:82584|PMID:8703054) UniProt PMID:8703054 MGI:82584 NCBI chrNW_004936531:7,625,956...7,629,041 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12170
    cellular process 11365
      cellular metabolic process 7015
        cellular biosynthetic process 3824
          C21-steroid hormone biosynthetic process 15
            aldosterone biosynthetic process + 9
            progesterone biosynthetic process + 5
Path 2
Term Annotations click to browse term
  biological_process 12170
    metabolic process 7645
      primary metabolic process 6749
        lipid metabolic process 960
          lipid biosynthetic process 487
            steroid biosynthetic process 120
              steroid hormone biosynthetic process 25
                C21-steroid hormone biosynthetic process 15
                  aldosterone biosynthetic process + 9
                  progesterone biosynthetic process + 5
paths to the root