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ONTOLOGY REPORT - ANNOTATIONS


Term:icosanoid metabolic process
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Accession:GO:0006690 term browser browse the term
Definition:The chemical reactions and pathways involving icosanoids, any of a group of C20 polyunsaturated fatty acids.
Synonyms:exact_synonym: eicosanoid metabolic process;   eicosanoid metabolism;   icosanoid metabolism



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icosanoid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 involved_in ISO (PMID:19737933) RGD PMID:19737933 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
JBrowse link
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 involved_in ISO (PMID:21068195) RGD PMID:21068195 NCBI chr 1:81,309,948...81,325,303
Ensembl chr 1:81,310,451...81,325,303
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 IDA RGD PMID:10486137 RGD:2301713 NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046
JBrowse link
G Daglb diacylglycerol lipase, beta involved_in ISS
ISO
GO_REF:0000024
(MGI:6414691|PMID:23103940)
UniProt
RGD
PMID:23103940 GO_REF:0000024 MGI:6414691 NCBI chr12:11,059,732...11,102,170
Ensembl chr12:11,059,732...11,102,154
JBrowse link
G Ptgis prostaglandin I2 synthase involved_in ISO (PMID:15115769) RGD PMID:15115769 NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451
JBrowse link
G Tbxas1 thromboxane A synthase 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:17459323)
UniProt
RGD
PMID:17459323 GO_REF:0000024 NCBI chr 4:67,664,963...67,837,096
Ensembl chr 4:67,665,007...67,837,096
JBrowse link
arachidonic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12 arachidonate 12-lipoxygenase, 12S type involved_in ISO
IBA
IDA
(PMID:1851637), (PMID:8319693)
GO_REF:0000033
(MGI:1202206|PMID:9501222), (MGI:66203|PMID:8188678)
PMID:23382512
RGD
GO_Central
PMID:1851637 PMID:8188678 PMID:8319693 PMID:9501222 PMID:23382512 GO_REF:0000033 MGI:1202206 MGI:66203, RGD:8554649 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542
JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type involved_in IEA
IBA
ISO
IDA
GO_REF:0000107
GO_REF:0000033
(MGI:1313249|PMID:10100631), (MGI:3608217|PMID:16129665), (MGI:6316908|PMID:11256953)
(PMID:15629692)
PMID:23382512
Ensembl
GO_Central
RGD
PMID:10100631 PMID:11256953 PMID:15629692 PMID:16129665 PMID:23382512 GO_REF:0000033 GO_REF:0000107 MGI:1313249 MGI:3608217 MGI:6316908, RGD:8554649 NCBI chr10:53,863,060...53,874,938
Ensembl chr10:53,863,060...53,874,938
JBrowse link
G Alox12e arachidonate 12-lipoxygenase, epidermal involved_in IDA
IBA
IEA
PMID:23382512
GO_REF:0000033
GO_REF:0000107
GO_Central
Ensembl
PMID:23382512 GO_REF:0000033 GO_REF:0000107, RGD:8554649 NCBI chr10:55,034,392...55,041,857
Ensembl chr10:55,034,392...55,041,928
JBrowse link
G Alox15 arachidonate 15-lipoxygenase involved_in IDA
IBA
IEA
ISO
NAS
GO_REF:0000033
GO_REF:0000117
(PMID:8305485)
(MGI:1101294|PMID:8798642), (MGI:66203|PMID:8188678)
PMID:15123652
(PMID:17052953), (PMID:1944593), (PMID:24282679), (PMID:8334154)
PMID:23382512
GO_Central
UniProt
RGD
PMID:1944593 PMID:8188678 PMID:8305485 PMID:8334154 PMID:8798642 More... GO_REF:0000033 GO_REF:0000117 MGI:1101294 MGI:66203, RGD:70288, RGD:5509794, RGD:8554649 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874
JBrowse link
G Alox15b arachidonate 15-lipoxygenase, type B involved_in IEA
IBA
ISO
IDA
GO_REF:0000107
GO_REF:0000033
(MGI:1097306|PMID:9305900)
(PMID:10542053), (PMID:10625675), (PMID:24282679), (PMID:24497644), (PMID:27145229), (PMID:9177185)
PMID:23382512
Ensembl
GO_Central
RGD
PMID:9177185 PMID:9305900 PMID:10542053 PMID:10625675 PMID:24282679 More... GO_REF:0000033 GO_REF:0000107 MGI:1097306, RGD:8554649 NCBI chr10:53,892,496...53,901,812
Ensembl chr10:53,892,466...53,901,812
JBrowse link
G Alox5 arachidonate 5-lipoxygenase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Aloxe3 arachidonate lipoxygenase 3 involved_in IDA
IBA
ISO
PMID:23382512
GO_REF:0000033
(MGI:3694035|PMID:17045234)
(PMID:12881489), (PMID:17045234)
GO_Central
RGD
PMID:12881489 PMID:17045234 PMID:23382512 GO_REF:0000033 MGI:3694035, RGD:8554649 NCBI chr10:53,830,219...53,854,328
Ensembl chr10:53,831,264...53,854,328
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 involved_in IEA
ISO
ISS
GO_REF:0000041
(MGI:5572883|PMID:15258110)
GO_REF:0000024
GO_REF:0000107
(PMID:15258110)
UniProt
RGD
Ensembl
PMID:15258110 GO_REF:0000024 GO_REF:0000041 GO_REF:0000107 MGI:5572883 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2ab1 cytochrome P450, family 2, subfamily ab, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:80,582,633...80,591,217
Ensembl chr11:80,582,938...80,590,873
JBrowse link
G Cyp2c23 cytochrome P450, family 2, subfamily c, polypeptide 23 NAS RGD PMID:8514789 RGD:727619 NCBI chr 1:242,889,218...242,913,869
Ensembl chr 1:242,889,224...242,913,858
JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 acts_upstream_of_or_within ISO (PMID:15102943) RGD PMID:15102943 NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 involved_in ISO (MGI:1277710|PMID:9721182) RGD PMID:9721182 MGI:1277710 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2d1 cytochrome P450, family 2, subfamily d, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:113,908,950...113,913,420
Ensembl chr 7:113,908,947...113,922,084
JBrowse link
G Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:113,935,138...113,939,209
Ensembl chr 7:113,935,138...113,939,209
JBrowse link
G Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:113,917,711...113,922,068
Ensembl chr 7:113,908,947...113,922,084
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 involved_in IDA
IBA
GO_REF:0000033 GO_Central
RGD
PMID:10945868 GO_REF:0000033, RGD:1599723 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp2d5 cytochrome P450, family 2, subfamily d, polypeptide 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:113,899,905...113,904,458
Ensembl chr 7:113,899,890...113,904,495
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 involved_in IDA
IEA
GO_REF:0000041 UniProt
RGD
PMID:9143331 GO_REF:0000041, RGD:632631 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 involved_in IMP
IBA
GO_REF:0000033 GO_Central
RGD
PMID:12857783 GO_REF:0000033, RGD:1625451 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
JBrowse link
G Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 involved_in TAS
IBA
IMP
GO_REF:0000033 GO_Central
RGD
PMID:12060587 PMID:12857783 GO_REF:0000033, RGD:628319, RGD:1625451 NCBI chr 5:128,922,355...128,934,188
Ensembl chr 5:128,923,615...128,934,165
JBrowse link
G Cyp4a2l1 cytochrome P450, family 4, subfamily a, polypeptide 2 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:129,010,501...129,021,087
Ensembl chr 5:128,923,615...129,026,477
JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 involved_in IMP
IBA
GO_REF:0000033 GO_Central
RGD
PMID:12857783 GO_REF:0000033, RGD:1625451 NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463
JBrowse link
G Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 involved_in IDA
IBA
GO_REF:0000033 GO_Central
RGD
PMID:15618658 GO_REF:0000033, RGD:2303409 NCBI chr 5:128,702,130...128,733,476
Ensembl chr 5:128,702,131...128,733,476
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 involved_in IDA
IBA
GO_REF:0000033 GO_Central
RGD
PMID:16415532 GO_REF:0000033, RGD:2301706 NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046
JBrowse link
G Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:11,717,208...11,733,507
Ensembl chr 7:11,717,208...11,733,506
JBrowse link
G Cyp4f40 cytochrome P450, family 4, subfamily f, polypeptide 40 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:11,691,648...11,707,437
Ensembl chr 7:11,692,086...11,706,229
JBrowse link
G Dagla diacylglycerol lipase, alpha acts_upstream_of_or_within
involved_in
ISS
ISO
IBA
GO_REF:0000024
MGI:4438719 (PMID:20147530)
GO_REF:0000033
(MGI:6423248|PMID:17584991)
(PMID:14610053)
UniProt
RGD
GO_Central
PMID:14610053 PMID:17584991 PMID:20147530 GO_REF:0000024 GO_REF:0000033 MGI:6423248 NCBI chr 1:206,890,635...206,947,332
Ensembl chr 1:206,890,638...206,947,232
JBrowse link
G Daglb diacylglycerol lipase, beta involved_in
acts_upstream_of
ISO
IBA
IEA
ISS
(PMID:14610053)
MGI:3529581 (PMID:20147530)
GO_REF:0000033
GO_REF:0000107
(MGI:6414691|PMID:23103940)
RGD
GO_Central
Ensembl
PMID:14610053 PMID:20147530 PMID:23103940 PMID:23103940 GO_REF:0000033 GO_REF:0000107 MGI:6414691, RGD:25671391 NCBI chr12:11,059,732...11,102,170
Ensembl chr12:11,059,732...11,102,154
JBrowse link
G Ephx1 epoxide hydrolase 1 involved_in ISO
IBA
ISS
(PMID:24958911)
GO_REF:0000033
GO_REF:0000024
RGD
GO_Central
UniProt
PMID:24958911 GO_REF:0000024 GO_REF:0000033 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Fads1 fatty acid desaturase 1 IMP RGD PMID:11414679 RGD:632758 NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734
JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:893248|PMID:9195979)
GO_REF:0000024
(PMID:11115402)
Ensembl
RGD
UniProt
PMID:9195979 PMID:11115402 GO_REF:0000024 GO_REF:0000107 MGI:893248 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx4 glutathione peroxidase 4 involved_in ISO
ISS
(PMID:11115402)
GO_REF:0000024
RGD
UniProt
PMID:11115402 GO_REF:0000024 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Mapk3 mitogen activated protein kinase 3 IEP RGD PMID:15027896 RGD:1626220 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mgll monoglyceride lipase involved_in ISS
ISO
GO_REF:0000024
(MGI:4836780|PMID:20729846)
UniProt
RGD
PMID:20729846 GO_REF:0000024 MGI:4836780 NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179
JBrowse link
G Pla2g2f phospholipase A2, group IIF involved_in ISO (MGI:6467677|PMID:11877435) RGD PMID:11877435 MGI:6467677 NCBI chr 5:150,986,788...150,993,175
Ensembl chr 5:150,986,788...150,993,175
JBrowse link
G Pla2g4a phospholipase A2 group 4A involved_in IMP
IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
GO_REF:0000041
(PMID:7794891)
Ensembl
UniProt
RGD
PMID:7794891 PMID:16603549 GO_REF:0000024 GO_REF:0000041 GO_REF:0000107, RGD:1642459 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Pnpla8 patatin-like phospholipase domain containing 8 involved_in ISO
IBA
ISS
(PMID:10833412), (PMID:15695510), (PMID:28442572)
GO_REF:0000033
GO_REF:0000024
RGD
GO_Central
UniProt
PMID:10833412 PMID:15695510 PMID:28442572 GO_REF:0000024 GO_REF:0000033 NCBI chr 6:61,329,810...61,391,736
Ensembl chr 6:61,329,810...61,391,734
JBrowse link
cyclooxygenase pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb1 bradykinin receptor B1 involved_in ISO (PMID:23846981) RGD PMID:23846981 NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 involved_in IEA
IBA
ISO
GO_REF:0000107
GO_REF:0000033
(PMID:1380156)
Ensembl
GO_Central
RGD
PMID:1380156 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 involved_in
acts_upstream_of_or_within
ISS
ISO
IBA
GO_REF:0000024
(PMID:1419907)
GO_REF:0000033
(MGI:5315361|PMID:12925531)
(PMID:1380156), (PMID:7592599), (PMID:7947975)
UniProt
RGD
GO_Central
PMID:1380156 PMID:1419907 PMID:7592599 PMID:7947975 PMID:12925531 GO_REF:0000024 GO_REF:0000033 MGI:5315361 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Sco1 synthesis of cytochrome C oxidase 1 acts_upstream_of_or_within ISO MGI:2182095|MGI:5758867 (PMID:28973536) RGD PMID:28973536 NCBI chr10:51,744,656...51,757,246
Ensembl chr10:51,744,656...51,757,237
JBrowse link
G Sphk1 sphingosine kinase 1 IDA RGD PMID:18723875 RGD:2311353 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240
JBrowse link
epoxygenase P450 pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:82,263,833...82,289,487
Ensembl chr 1:82,263,833...82,289,487
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b12 cytochrome P450, family 2, subfamily b, polypeptide 12 involved_in IDA
IBA
GO_REF:0000033 GO_Central
RGD
PMID:9535921 GO_REF:0000033, RGD:2301469 NCBI chr 1:82,007,609...82,019,409
Ensembl chr 1:82,007,609...82,080,480
JBrowse link
G Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:82,094,188...82,106,492
Ensembl chr 1:82,094,180...82,106,492
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp2b21 cytochrome P450, family 2, subfamily b, polypeptide 21 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:81,886,097...81,915,066
Ensembl chr 1:81,886,098...81,915,066
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 involved_in IDA
IBA
PMID:10491410
GO_REF:0000033
GO_Central PMID:10491410 GO_REF:0000033, RGD:39458017 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:238,699,859...238,757,011
Ensembl chr 1:238,699,854...238,757,019
JBrowse link
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:238,786,764...238,867,195
Ensembl chr 1:238,786,765...238,867,191
JBrowse link
G Cyp2c22 cytochrome P450, family 2, subfamily c, polypeptide 22 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:238,991,698...239,031,323
Ensembl chr 1:238,991,610...239,021,738
JBrowse link
G Cyp2c23 cytochrome P450, family 2, subfamily c, polypeptide 23 involved_in IDA
IBA
PMID:8246128
GO_REF:0000033
PMID:14742258
PMID:10491410
GO_Central PMID:8246128 PMID:14742258 PMID:10491410 GO_REF:0000033, RGD:39458010, RGD:39458011, RGD:39458017 NCBI chr 1:242,889,218...242,913,869
Ensembl chr 1:242,889,224...242,913,858
JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238
JBrowse link
G Cyp2c55 cytochrome P450, family 2, subfamily c, polypeptide 55 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:237,009,411...237,054,555
Ensembl chr 1:237,009,368...237,054,564
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2c6v1l1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:237,244,891...237,283,416
Ensembl chr 1:237,244,885...237,283,160
JBrowse link
G Cyp2c7 cytochrome P450, family 2, subfamily c, polypeptide 7 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:237,332,641...237,388,714
Ensembl chr 1:237,332,659...237,388,709
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 involved_in ISO (PMID:7574697) RGD PMID:7574697
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:82,416,107...82,429,897
Ensembl chr 1:82,416,130...82,429,896
JBrowse link
G Cyp2g1 cytochrome P450, family 2, subfamily g, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:82,145,635...82,156,862
Ensembl chr 1:82,145,073...82,156,828
JBrowse link
G Cyp2j3 cytochrome P450, family 2, subfamily j, polypeptide 3 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 5:111,219,921...111,244,987
Ensembl chr 5:111,178,703...111,244,794
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 involved_in ISO (PMID:11901223), (PMID:8631948) RGD PMID:8631948 PMID:11901223 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
JBrowse link
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:81,309,948...81,325,303
Ensembl chr 1:81,310,451...81,325,303
JBrowse link
G Cyp2t1 cytochrome P450, family 2, subfamily t, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:82,446,321...82,451,564
Ensembl chr 1:82,446,921...82,451,563
JBrowse link
G LOC103691092 cytochrome P450 2B9-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:81,791,776...81,810,482
Ensembl chr 1:81,784,649...81,810,482
JBrowse link
icosanoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox15 arachidonate 15-lipoxygenase involved_in NAS PMID:15123652 UniProt PMID:15123652 RGD:5509794 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 involved_in IDA PMID:15766564 UniProt PMID:15766564 RGD:14402444 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2c23 cytochrome P450, family 2, subfamily c, polypeptide 23 involved_in IDA PMID:15766564 UniProt PMID:15766564 RGD:14402444 NCBI chr 1:242,889,218...242,913,869
Ensembl chr 1:242,889,224...242,913,858
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 involved_in ISO (PMID:15766564) RGD PMID:15766564
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 involved_in IMP
IBA
GO_REF:0000033 GO_Central
RGD
PMID:12857783 GO_REF:0000033, RGD:1625451 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
JBrowse link
G Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 involved_in IMP
IBA
GO_REF:0000033 GO_Central
RGD
PMID:12857783 GO_REF:0000033, RGD:1625451 NCBI chr 5:128,922,355...128,934,188
Ensembl chr 5:128,923,615...128,934,165
JBrowse link
G Cyp4a2l1 cytochrome P450, family 4, subfamily a, polypeptide 2 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:129,010,501...129,021,087
Ensembl chr 5:128,923,615...129,026,477
JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 involved_in IMP
IBA
GO_REF:0000033 GO_Central
RGD
PMID:12857783 GO_REF:0000033, RGD:1625451 NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463
JBrowse link
G Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:128,702,130...128,733,476
Ensembl chr 5:128,702,131...128,733,476
JBrowse link
G Pla2g4a phospholipase A2 group 4A acts_upstream_of_or_within ISO (PMID:17293613) RGD PMID:17293613 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
leukotriene A4 biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:24282679), (PMID:31664810)
(MGI:6392995|PMID:31642348)
UniProt
Ensembl
RGD
PMID:24282679 PMID:31642348 PMID:31664810 GO_REF:0000024 GO_REF:0000107 MGI:6392995 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
leukotriene A4 metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12 arachidonate 12-lipoxygenase, 12S type involved_in
NOT|involved_in
ISO
ISS
(PMID:8250832)
GO_REF:0000024
(PMID:1851637)
RGD
UniProt
PMID:1851637 PMID:8250832 GO_REF:0000024 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542
JBrowse link
leukotriene B4 catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 involved_in IDA
IBA
PMID:14634044
GO_REF:0000033
PMID:10486137
GO_Central PMID:14634044 PMID:10486137 GO_REF:0000033, RGD:2301710, RGD:2301713 NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046
JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 involved_in ISO (PMID:11461919), (PMID:9675028) RGD PMID:9675028 PMID:11461919 NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940
JBrowse link
G Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 involved_in IDA
IBA
PMID:9344476
GO_REF:0000033
PMID:14634044
GO_Central PMID:9344476 PMID:14634044 GO_REF:0000033, RGD:15090848, RGD:2301710 NCBI chr 7:11,717,208...11,733,507
Ensembl chr 7:11,717,208...11,733,506
JBrowse link
G Cyp4f40 cytochrome P450, family 4, subfamily f, polypeptide 40 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:11,691,648...11,707,437
Ensembl chr 7:11,692,086...11,706,229
JBrowse link
leukotriene B4 metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 involved_in ISO
ISS
IEA
(MGI:3640626|PMID:16380383)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:16380383 GO_REF:0000024 GO_REF:0000107 MGI:3640626 NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940
JBrowse link
G Ptgr1 prostaglandin reductase 1 involved_in ISS
IDA
ISO
GO_REF:0000024
(PMID:8394361)
UniProt
RGD
PMID:8394361 PMID:9667737 GO_REF:0000024, RGD:401959219 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
JBrowse link
leukotriene biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase acts_upstream_of_or_within
involved_in
TAS
ISO
ISS
(PMID:19075240)
(MGI:1933116|PMID:7809134)
GO_REF:0000024
(PMID:21233389), (PMID:24893149)
RGD
UniProt
PMID:7809134 PMID:19075240 PMID:21233389 PMID:24893149 PMID:3417684 GO_REF:0000024 MGI:1933116, RGD:632194 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein acts_upstream_of_or_within
involved_in
IDA
ISO
IBA
MGI:2156546 (PMID:19075240), (PMID:9091580)
GO_REF:0000033
(PMID:2300173)
RGD
GO_Central
PMID:2300173 PMID:9091580 PMID:19075240 PMID:2300173 PMID:19075240 GO_REF:0000033, RGD:69749, RGD:2313889 NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986
JBrowse link
G Fcer1a Fc epsilon receptor Ia acts_upstream_of_or_within ISO (PMID:9000133) RGD PMID:9000133 NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351
JBrowse link
G Lta4h leukotriene A4 hydrolase involved_in ISO
IBA
ISS
(PMID:11675384), (PMID:15078870), (PMID:9774412)
GO_REF:0000033
GO_REF:0000024
RGD
GO_Central
UniProt
PMID:9774412 PMID:11675384 PMID:15078870 GO_REF:0000024 GO_REF:0000033 NCBI chr 7:27,969,796...28,001,600
Ensembl chr 7:27,969,789...28,001,600
JBrowse link
G Ltc4s leukotriene C4 synthase involved_in TAS
IEA
IBA
IDA
GO_REF:0000104
GO_REF:0000033
UniProt
GO_Central
RGD
PMID:12767051 PMID:14637132 GO_REF:0000033 GO_REF:0000104, RGD:724432, RGD:2302289 NCBI chr10:34,560,476...34,562,790
Ensembl chr10:34,560,360...34,562,651
JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 involved_in ISO
IBA
(PMID:23409838), (PMID:8703034), (PMID:9092565)
GO_REF:0000033
RGD
GO_Central
PMID:8703034 PMID:9092565 PMID:23409838 GO_REF:0000033 NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828
JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 involved_in ISO (PMID:9278457) RGD PMID:9278457 NCBI chr13:79,526,541...79,547,479
Ensembl chr13:79,526,541...79,547,411
JBrowse link
G Pla2g1b phospholipase A2 group IB involved_in ISO (PMID:16005851) RGD PMID:16005851 NCBI chr12:41,142,193...41,151,967
Ensembl chr12:41,142,200...41,153,226
JBrowse link
G Pla2g4a phospholipase A2 group 4A involved_in ISO
IEA
(PMID:18451993)
GO_REF:0000043
GO_REF:0000107
(MGI:1100763|PMID:9403693)
RGD
UniProt
Ensembl
PMID:9403693 PMID:18451993 GO_REF:0000043 GO_REF:0000107 MGI:1100763 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Pla2g5 phospholipase A2, group V involved_in IDA
IEA
ISO
GO_REF:0000107
(PMID:20432503)
Ensembl
RGD
PMID:20432503 PMID:11106649 GO_REF:0000107, RGD:2303037 NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658
JBrowse link
G Prg3 proteoglycan 3, pro eosinophil major basic protein 2 involved_in ISO (PMID:10318872) RGD PMID:10318872 NCBI chr 3:70,071,970...70,078,103
Ensembl chr 3:70,072,497...70,078,102
JBrowse link
G Syk spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2384078 (PMID:9000133)
Ensembl
RGD
PMID:9000133 GO_REF:0000107 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
JBrowse link
leukotriene D4 biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ggt1 gamma-glutamyltransferase 1 involved_in ISO (PMID:14754911), (PMID:21447318) RGD PMID:14754911 PMID:21447318 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
G Ggt5 gamma-glutamyltransferase 5 involved_in
acts_upstream_of_or_within
ISO
IBA
IEA
ISS
(PMID:1676842), (PMID:21447318)
MGI:2182354 (PMID:12163373), (PMID:9774450)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024
RGD
GO_Central
Ensembl
UniProt
PMID:1676842 PMID:9774450 PMID:12163373 PMID:21447318 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr20:13,043,255...13,071,523
Ensembl chr20:13,043,257...13,071,450
JBrowse link
leukotriene D4 catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dpep1 dipeptidase 1 involved_in ISO
ISS
(PMID:32325220)
GO_REF:0000024
RGD
UniProt
PMID:32325220 GO_REF:0000024 NCBI chr19:51,209,831...51,237,004
Ensembl chr19:51,219,660...51,235,257
JBrowse link
G Dpep2 dipeptidase 2 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:32325220)
UniProt
Ensembl
RGD
PMID:32325220 GO_REF:0000024 GO_REF:0000107 NCBI chr19:33,883,557...33,896,487
Ensembl chr19:33,885,478...33,891,954
JBrowse link
leukotriene metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc10 ATP binding cassette subfamily C member 10 involved_in ISO (PMID:23087055) RGD PMID:23087055 NCBI chr 9:14,657,242...14,677,178
Ensembl chr 9:14,657,264...14,677,178
JBrowse link
G Alox5 arachidonate 5-lipoxygenase acts_upstream_of_or_within ISO MGI:1857125 (PMID:11867678) RGD PMID:11867678 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Cpa1 carboxypeptidase A1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 4:59,257,417...59,263,544
Ensembl chr 4:59,257,417...59,263,544
JBrowse link
G Cyp4f5 cytochrome P450, family 4, subfamily f, polypeptide 5 IMP RGD PMID:12646265 RGD:1299398 NCBI chr 7:11,544,040...11,558,982
Ensembl chr 7:11,544,082...11,558,978
JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 IMP RGD PMID:12646265 RGD:1299398 NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782
JBrowse link
G Dpep1 dipeptidase 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:1203838|PMID:9560193), (MGI:2669357|PMID:12738806)
UniProt
RGD
PMID:9560193 PMID:12738806 GO_REF:0000024 MGI:1203838 MGI:2669357 NCBI chr19:51,209,831...51,237,004
Ensembl chr19:51,219,660...51,235,257
JBrowse link
G Dpep2 dipeptidase 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:2669357|PMID:12738806)
UniProt
RGD
PMID:12738806 GO_REF:0000024 MGI:2669357 NCBI chr19:33,883,557...33,896,487
Ensembl chr19:33,885,478...33,891,954
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 involved_in ISO (PMID:21447318) RGD PMID:21447318 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
G Lta4h leukotriene A4 hydrolase IDA RGD PMID:3995081 RGD:2316605 NCBI chr 7:27,969,796...28,001,600
Ensembl chr 7:27,969,789...28,001,600
JBrowse link
G Ltc4s leukotriene C4 synthase involved_in
acts_upstream_of_or_within
ISO (PMID:9153254)
(PMID:8706658)
RGD PMID:8706658 PMID:9153254 NCBI chr10:34,560,476...34,562,790
Ensembl chr10:34,560,360...34,562,651
JBrowse link
G Mgst3l1 microsomal glutathione S-transferase 3 like 1 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr14:19,525,509...19,526,128
Ensembl chr14:19,525,558...19,526,016
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 acts_upstream_of_or_within ISO MGI:1934143 (PMID:11867678) RGD PMID:11867678 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
JBrowse link
G Tlr2 toll-like receptor 2 IDA RGD PMID:21765618 RGD:7241098 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tlr4 toll-like receptor 4 IDA RGD PMID:21765618 RGD:7241098 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
lipoxygenase pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12 arachidonate 12-lipoxygenase, 12S type involved_in ISO
IBA
IDA
(PMID:8319693)
GO_REF:0000033
(MGI:1202206|PMID:9501222), (MGI:66203|PMID:8188678)
PMID:23382512
RGD
GO_Central
PMID:8188678 PMID:8319693 PMID:9501222 PMID:23382512 GO_REF:0000033 MGI:1202206 MGI:66203, RGD:8554649 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542
JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type involved_in IEA
IBA
ISO
ISS
GO_REF:0000107
GO_REF:0000033
(PMID:15629692), (PMID:21558561)
GO_REF:0000024
Ensembl
GO_Central
RGD
UniProt
PMID:15629692 PMID:21558561 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr10:53,863,060...53,874,938
Ensembl chr10:53,863,060...53,874,938
JBrowse link
G Alox12e arachidonate 12-lipoxygenase, epidermal involved_in IDA
IBA
IEA
PMID:23382512
GO_REF:0000033
GO_REF:0000107
GO_Central
Ensembl
PMID:23382512 GO_REF:0000033 GO_REF:0000107, RGD:8554649 NCBI chr10:55,034,392...55,041,857
Ensembl chr10:55,034,392...55,041,928
JBrowse link
G Alox15 arachidonate 15-lipoxygenase involved_in IDA
IBA
IEA
ISO
GO_REF:0000033
GO_REF:0000117
(PMID:8305485)
(MGI:1101294|PMID:8798642), (MGI:66203|PMID:8188678)
(PMID:1944593), (PMID:23242647)
GO_Central
UniProt
RGD
PMID:1944593 PMID:8188678 PMID:8305485 PMID:8798642 PMID:23242647 More... GO_REF:0000033 GO_REF:0000117 MGI:1101294 MGI:66203, RGD:70288 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874
JBrowse link
G Alox15b arachidonate 15-lipoxygenase, type B involved_in IDA
IBA
ISO
IEA
PMID:23382512
GO_REF:0000033
(MGI:1097306|PMID:9305900)
GO_REF:0000107
GO_Central
RGD
Ensembl
PMID:9305900 PMID:23382512 GO_REF:0000033 GO_REF:0000107 MGI:1097306, RGD:8554649 NCBI chr10:53,892,496...53,901,812
Ensembl chr10:53,892,466...53,901,812
JBrowse link
G Alox5 arachidonate 5-lipoxygenase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein IMP
IDA
RGD PMID:18945963 PMID:17517102 RGD:2313900, RGD:2313910 NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986
JBrowse link
G Aloxe3 arachidonate lipoxygenase 3 involved_in ISS
IBA
ISO
GO_REF:0000024
GO_REF:0000033
(PMID:20921226)
UniProt
GO_Central
RGD
PMID:20921226 GO_REF:0000024 GO_REF:0000033 NCBI chr10:53,830,219...53,854,328
Ensembl chr10:53,831,264...53,854,328
JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in ISO
IEA
ISS
(PMID:11115402)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:11115402 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx4 glutathione peroxidase 4 involved_in ISO
ISS
(PMID:11115402)
GO_REF:0000024
RGD
UniProt
PMID:11115402 GO_REF:0000024 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Pla2g3 phospholipase A2, group III acts_upstream_of_or_within ISO MGI:4461174 (PMID:20424323) RGD PMID:20424323 NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913
JBrowse link
negative regulation of prostaglandin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir204 microRNA 204 involved_in ISO (PMID:29441883) RGD PMID:29441883 NCBI chr 1:220,316,931...220,317,040
Ensembl chr 1:220,316,931...220,317,040
JBrowse link
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in ISO (PMID:3863495) RGD PMID:3863495 NCBI chr15:75,850,389...76,019,711
Ensembl chr15:75,850,624...76,019,712
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA
(MGI:5306564|PMID:20042607)
GO_REF:0000107
RGD
Ensembl
PMID:20042607 GO_REF:0000107 MGI:5306564 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
omega-hydroxylase P450 pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor IMP RGD PMID:19889059 RGD:401794453 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Cyp2u1 cytochrome P450, family 2, subfamily u, polypeptide 1 involved_in ISO (PMID:24563460) RGD PMID:24563460 NCBI chr 2:219,849,403...219,866,959
Ensembl chr 2:219,849,407...219,866,882
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 NOT|involved_in ISO (PMID:10860550) RGD PMID:10860550 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 involved_in IDA PMID:14634044 UniProt PMID:14634044 RGD:2301710 NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046
JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 involved_in ISO (PMID:15364545)
(PMID:18577768)
RGD PMID:15364545 PMID:18577768 NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940
JBrowse link
G Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 involved_in IDA PMID:14634044 UniProt PMID:14634044 RGD:2301710 NCBI chr 7:11,717,208...11,733,507
Ensembl chr 7:11,717,208...11,733,506
JBrowse link
positive regulation of prostaglandin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 IMP RGD PMID:8260938 RGD:2306959 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Avp arginine vasopressin IMP RGD PMID:17254553 RGD:2300349 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
JBrowse link
G Avpr1a arginine vasopressin receptor 1A IMP RGD PMID:17254553 RGD:2300349 NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215
JBrowse link
G Cd74 CD74 molecule involved_in ISO
IEA
(PMID:24569872)
GO_REF:0000107
RGD
Ensembl
PMID:24569872 GO_REF:0000107 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Il1b interleukin 1 beta involved_in ISO RNAcentral:URS0000424278_9606 (PMID:29384235) RGD PMID:29384235 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IMP RGD PMID:9786861 RGD:2304243 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Pla2g3 phospholipase A2, group III involved_in ISO (PMID:23624557)
(MGI:5492190|PMID:23624557)
RGD PMID:23624557 MGI:5492190 NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913
JBrowse link
G Pla2g4a phospholipase A2 group 4A IMP RGD PMID:16203828 RGD:1642461 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO (PMID:24287039) RGD PMID:24287039 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 involved_in ISO (PMID:21716255)
(MGI:5474549|PMID:21716255)
RGD PMID:21716255 MGI:5474549 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
prostaglandin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07054614.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Akr1c15 aldo-keto reductase family 1, member C15 involved_in ISO (PMID:25726376) RGD PMID:25726376 NCBI chr17:66,181,493...66,208,090
Ensembl chr17:66,181,493...66,208,061
JBrowse link
G Cd74 CD74 molecule involved_in ISO
IEA
ISS
(PMID:12782713)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:12782713 GO_REF:0000024 GO_REF:0000107 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Daglb diacylglycerol lipase, beta involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:6414691|PMID:23103940)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:23103940 GO_REF:0000024 GO_REF:0000107 MGI:6414691 NCBI chr12:11,059,732...11,102,170
Ensembl chr12:11,059,732...11,102,154
JBrowse link
G Edn1 endothelin 1 involved_in ISO (PMID:9492062) RGD PMID:9492062 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Edn2 endothelin 2 involved_in IEA
ISO
GO_REF:0000107
(MGI:3847878|PMID:9492062)
(PMID:9492062)
Ensembl
RGD
PMID:9492062 GO_REF:0000107 MGI:3847878 NCBI chr 5:133,751,316...133,756,814
Ensembl chr 5:133,751,217...133,756,814
JBrowse link
G Hpgds hematopoietic prostaglandin D synthase TAS RGD PMID:9323136 RGD:68838 NCBI chr 4:94,368,426...94,397,931
Ensembl chr 4:94,373,342...94,397,883
JBrowse link
G Mif macrophage migration inhibitory factor involved_in ISO (PMID:12782713) RGD PMID:12782713 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
G Pla2g10 phospholipase A2, group X involved_in IEA
ISO
GO_REF:0000107
(MGI:5818640|PMID:27292189)
Ensembl
RGD
PMID:27292189 GO_REF:0000107 MGI:5818640 NCBI chr10:1,597,761...1,610,822
Ensembl chr10:1,597,761...1,609,000
JBrowse link
G Pla2g2a phospholipase A2 group IIA involved_in ISO (MGI:5818640|PMID:27292189) RGD PMID:27292189 MGI:5818640 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
JBrowse link
G Pla2g4a phospholipase A2 group 4A involved_in ISO
IEA
ISS
(PMID:18451993), (PMID:27642067)
GO_REF:0000043
GO_REF:0000107
(MGI:1100762|PMID:9403692), (MGI:1100763|PMID:9403693)
GO_REF:0000024
GO_REF:0000041
RGD
UniProt
Ensembl
PMID:9403692 PMID:9403693 PMID:18451993 PMID:27642067 GO_REF:0000024 GO_REF:0000041 GO_REF:0000043 GO_REF:0000107 MGI:1100762 MGI:1100763 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Pla2g4f phospholipase A2, group IVF acts_upstream_of_or_within ISO (PMID:17293613) RGD PMID:17293613 NCBI chr 3:107,249,053...107,266,201
Ensembl chr 3:107,250,075...107,264,689
JBrowse link
G Pnpla8 patatin-like phospholipase domain containing 8 involved_in ISO (PMID:15695510) RGD PMID:15695510 NCBI chr 6:61,329,810...61,391,736
Ensembl chr 6:61,329,810...61,391,734
JBrowse link
G Prxl2b peroxiredoxin like 2B involved_in ISS
IBA
ISO
PMID:18006499
GO_REF:0000033
(MGI:3771130|PMID:18006499)
GO_REF:0000024
(PMID:18006499)
GO_Central
RGD
UniProt
PMID:18006499 PMID:18006499 GO_REF:0000024 GO_REF:0000033 MGI:3771130, RGD:8552775 NCBI chr 5:165,462,610...165,465,213 JBrowse link
G Ptgds prostaglandin D2 synthase involved_in IDA
ISO
PMID:7836410
(MGI:3761957|PMID:17715133)
(PMID:20347284), (PMID:20667974)
RGD PMID:17715133 PMID:20347284 PMID:20667974 PMID:7836410 MGI:3761957, RGD:8553429 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833
JBrowse link
G Ptges prostaglandin E synthase involved_in TAS
IBA
ISO
IEA
IDA
GO_REF:0000033
(MGI:6393388|PMID:11795891)
(PMID:25726376)
(PMID:18682561)
GO_REF:0000041
GO_Central
RGD
UniProt
PMID:11795891 PMID:18682561 PMID:25726376 PMID:11067848 PMID:11067848 GO_REF:0000033 GO_REF:0000041 MGI:6393388, RGD:67929, RGD:67929 NCBI chr 3:14,177,892...14,189,236 JBrowse link
G Ptges2 prostaglandin E synthase 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 3:15,690,501...15,697,688
Ensembl chr 3:15,690,501...15,697,688
JBrowse link
G Ptges3 prostaglandin E synthase 3 acts_upstream_of_or_within
involved_in
IMP
ISO
IBA
IEA
ISS
IDA
MGI:3701300 (PMID:17438133)
GO_REF:0000033
GO_REF:0000043
GO_REF:0000041
GO_REF:0000024
(PMID:10922363)
RGD
GO_Central
UniProt
PMID:10922363 PMID:17438133 PMID:10922363 PMID:10922363 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 GO_REF:0000043, RGD:5688071, RGD:5688071 NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084
JBrowse link
G Ptges3l1 prostaglandin E synthase 3-like 1 involved_in IEA
IBA
GO_REF:0000041
GO_REF:0000033
UniProt
GO_Central
GO_REF:0000033 GO_REF:0000041 NCBI chr  X:42,215,200...42,224,472
Ensembl chr  X:42,214,756...42,225,047
JBrowse link
G Ptgis prostaglandin I2 synthase involved_in IMP
IBA
IEA
ISO
ISS
IDA
GO_REF:0000033
GO_REF:0000107
GO_REF:0000002
(PMID:15115769), (PMID:20122998), (PMID:21296955)
GO_REF:0000024
GO_Central
Ensembl
InterPro
RGD
UniProt
PMID:15115769 PMID:20122998 PMID:21296955 PMID:10359560 PMID:10536678 More... GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:727270, RGD:401959739, RGD:1580695, RGD:8693629 NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 acts_upstream_of_or_within
involved_in
IMP
ISO
ISS
MGI:1857238 (PMID:12093889)
GO_REF:0000024
RGD
UniProt
PMID:12093889 PMID:17673564 GO_REF:0000024, RGD:2300259 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 involved_in IMP
ISO
(MGI:5315361|PMID:12925531)
(PMID:27642067)
RGD PMID:12925531 PMID:27642067 PMID:17673564 MGI:5315361, RGD:2300259 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Tbxas1 thromboxane A synthase 1 involved_in ISO
ISS
(PMID:11097184)
GO_REF:0000024
RGD
UniProt
PMID:11097184 GO_REF:0000024 NCBI chr 4:67,664,963...67,837,096
Ensembl chr 4:67,665,007...67,837,096
JBrowse link
prostaglandin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acox1 acyl-CoA oxidase 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:7876265)
UniProt
Ensembl
RGD
PMID:7876265 GO_REF:0000024 GO_REF:0000107 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akr1b7 aldo-keto reductase family 1, member B7 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:63,053,560...63,100,934
Ensembl chr 4:63,076,800...63,089,502
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
JBrowse link
G Akr1c14 aldo-keto reductase family 1, member C14 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:66,156,286...66,173,277
Ensembl chr17:66,156,288...66,173,277
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 involved_in ISO (PMID:8573067) RGD PMID:8573067 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 involved_in ISO
IBA
(PMID:20036328), (PMID:9792917)
GO_REF:0000033
RGD
GO_Central
PMID:9792917 PMID:20036328 GO_REF:0000033 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G AKR1C3l1 aldo-keto reductase family 1 member C3-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:65,847,580...65,881,488
Ensembl chr17:65,835,634...65,881,488
JBrowse link
G Atp6v1b1 ATPase H+ transporting V1 subunit B1 acts_upstream_of_or_within ISO MGI:2673510 (PMID:24051376) RGD PMID:24051376 NCBI chr 4:116,223,799...116,242,475
Ensembl chr 4:116,223,799...116,242,475
JBrowse link
G Ces2h carboxylesterase 2H involved_in ISO (PMID:21049984) RGD PMID:21049984 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
JBrowse link
G Comt catechol-O-methyltransferase acts_upstream_of_or_within ISO MGI:2178542 (PMID:19770404) RGD PMID:19770404 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 involved_in ISO (PMID:21068195) RGD PMID:21068195 NCBI chr 1:81,309,948...81,325,303
Ensembl chr 1:81,310,451...81,325,303
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 involved_in ISO (PMID:9084911) RGD PMID:9084911 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
JBrowse link
G Gstm1 glutathione S-transferase mu 1 involved_in ISO
ISS
(PMID:9084911)
GO_REF:0000024
RGD
UniProt
PMID:9084911 GO_REF:0000024 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:9084911)
UniProt
RGD
PMID:9084911 GO_REF:0000024 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase involved_in IDA
IBA
ISS
ISO
GO_REF:0000033
GO_REF:0000024
(PMID:16828555), (PMID:21072165)
GO_Central
UniProt
RGD
PMID:16828555 PMID:21072165 PMID:18058808 GO_REF:0000024 GO_REF:0000033, RGD:11667092 NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228
JBrowse link
G Hpgds hematopoietic prostaglandin D synthase involved_in
acts_upstream_of_or_within
ISO
ISS
(PMID:12627223)
(PMID:10824118)
GO_REF:0000024
RGD
UniProt
PMID:10824118 PMID:12627223 GO_REF:0000024 NCBI chr 4:94,368,426...94,397,931
Ensembl chr 4:94,373,342...94,397,883
JBrowse link
G Pdpn podoplanin acts_upstream_of_or_within ISO MGI:2657021 (PMID:16869965) RGD PMID:16869965 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656
JBrowse link
G Plaa phospholipase A2, activating protein involved_in ISS
ISO
GO_REF:0000024
(MGI:6103030|PMID:28007986)
UniProt
RGD
PMID:28007986 GO_REF:0000024 MGI:6103030 NCBI chr 5:109,428,600...109,460,373
Ensembl chr 5:109,428,265...109,460,282
JBrowse link
G Ptges prostaglandin E synthase acts_upstream_of_or_within ISO (PMID:10869354) RGD PMID:10869354 NCBI chr 3:14,177,892...14,189,236 JBrowse link
G Ptges3 prostaglandin E synthase 3 IMP RGD PMID:21334450 RGD:5688070 NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084
JBrowse link
G Ptgr1 prostaglandin reductase 1 involved_in ISO
IBA
IEA
(PMID:25619643)
GO_REF:0000033
GO_REF:0000117
(PMID:11688989)
RGD
GO_Central
UniProt
PMID:11688989 PMID:25619643 GO_REF:0000033 GO_REF:0000117 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
JBrowse link
G Ptgr2 prostaglandin reductase 2 involved_in ISO
IBA
IEA
ISS
(PMID:19000823)
GO_REF:0000033
GO_REF:0000117
GO_REF:0000024
RGD
GO_Central
UniProt
PMID:19000823 GO_REF:0000024 GO_REF:0000033 GO_REF:0000117 NCBI chr 6:103,931,367...103,963,113
Ensembl chr 6:103,931,409...103,963,111
JBrowse link
G Ptgr3 prostaglandin reductase 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr18:77,454,435...77,463,785
Ensembl chr18:77,454,435...77,463,785
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 acts_upstream_of_or_within ISO MGI:1857238 (PMID:10987272) RGD PMID:10987272 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
prostanoid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mgst3 microsomal glutathione S-transferase 3 involved_in ISO (PMID:36370807) RGD PMID:36370807 NCBI chr13:79,526,541...79,547,479
Ensembl chr13:79,526,541...79,547,411
JBrowse link
regulation of prostaglandin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fabp5 fatty acid binding protein 5 involved_in ISO (MGI:6157571|PMID:29440395) RGD PMID:29440395 MGI:6157571 NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19872
    metabolic process 11602
      cellular metabolic process 9669
        organic acid metabolic process 1025
          oxoacid metabolic process 1014
            carboxylic acid metabolic process 999
              icosanoid metabolic process 143
                arachidonic acid metabolic process + 70
                icosanoid biosynthetic process + 59
                leukotriene metabolic process + 30
                lipoxygenase pathway + 11
                prostanoid metabolic process + 61
paths to the root