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ONTOLOGY REPORT - ANNOTATIONS


Term:sphingomyelin biosynthetic process
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Accession:GO:0006686 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine.
Synonyms:exact_synonym: sphingomyelin anabolism;   sphingomyelin biosynthesis;   sphingomyelin formation;   sphingomyelin synthesis


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sphingomyelin biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 ISO MGI:1913862 (MGI:6393026|PMID:31880535) RGD PMID:31880535 MGI:6393026 NCBI chr 9:53,110,628...53,120,454
Ensembl chr 9:53,111,371...53,118,613
JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 ISO MGI:2137691|MGI:2181669|MGI:6382064 (MGI:6393026|PMID:31880535) RGD PMID:31880535 MGI:6393026 NCBI chr10:86,545,910...86,554,478
Ensembl chr10:86,547,339...86,554,478
JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase ISO (MGI:5707904|PMID:25667419) RGD PMID:25667419 MGI:5707904 NCBI chr10:46,339,821...46,404,640
Ensembl chr10:46,339,821...46,404,642
JBrowse link
G Sgms1 sphingomyelin synthase 1 ISS
ISO
IBA
GO_REF:0000024
(MGI:6221394|PMID:27892528)
(PMID:14685263), (PMID:14976195), (PMID:17982138)
PMID:21873635
HGNC
RGD
PMID:14685263, PMID:14976195, PMID:17982138, PMID:27892528, PMID:21873635 GO_REF:0000024, MGI:6221394, RGD:13792537 NCBI chr 1:250,692,448...250,951,685
Ensembl chr 1:250,691,370...250,951,697
JBrowse link
G Sgms2 sphingomyelin synthase 2 IEA
ISO
IBA
GO_REF:0000107
(MGI:5707904|PMID:25667419), (MGI:6221394|PMID:27892528)
PMID:21873635
(PMID:14685263), (PMID:17982138)
Ensembl
RGD
PMID:14685263, PMID:17982138, PMID:25667419, PMID:27892528, PMID:21873635 GO_REF:0000107, MGI:5707904, MGI:6221394, RGD:13792537 NCBI chr 2:236,458,276...236,530,667
Ensembl chr 2:236,458,279...236,480,502
JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 ISO MGI:3815115 (MGI:3814228|PMID:16216550), (MGI:5749304|PMID:26301690) RGD PMID:16216550, PMID:26301690 MGI:3814228, MGI:5749304 NCBI chr17:11,856,525...11,895,566
Ensembl chr17:11,856,525...11,895,566
JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 ISO MGI:3815117 (MGI:3814228|PMID:16216550) RGD PMID:16216550 MGI:3814228 NCBI chr 6:111,334,408...111,417,960
Ensembl chr 6:111,339,136...111,417,954
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      cellular metabolic process 11073
        cellular biosynthetic process 6056
          phospholipid biosynthetic process 193
            sphingomyelin biosynthetic process 7
Path 2
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      primary metabolic process 10900
        lipid metabolic process 1373
          cellular lipid metabolic process 1022
            membrane lipid metabolic process 191
              sphingolipid metabolic process 142
                sphingomyelin metabolic process 16
                  sphingomyelin biosynthetic process 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.