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ONTOLOGY REPORT - ANNOTATIONS

Term:sphingomyelin biosynthetic process
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Accession:GO:0006686 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine.
Synonyms:exact_synonym: sphingomyelin anabolism;   sphingomyelin biosynthesis;   sphingomyelin formation;   sphingomyelin synthesis


show annotations for term's descendants           Sort by:
sphingomyelin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca8 ATP binding cassette subfamily A member 8 involved_in ISO (PMID:23560799) RGD PMID:23560799 NCBI chr10:95,416,984...95,490,647
Ensembl chr10:94,917,520...94,990,988 		JBrowse link
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of ISO MGI:1913862 (PMID:31880535) RGD PMID:31880535 NCBI chr 9:55,735,081...55,745,287
Ensembl chr 9:48,237,572...48,253,211 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of ISO MGI:2137691|MGI:2181669|MGI:6382064 (PMID:31880535) RGD PMID:31880535 NCBI chr10:84,086,317...84,092,673
Ensembl chr10:83,590,071...83,598,620 		JBrowse link
G Osbp oxysterol binding protein involved_in ISO
IEA		 (PMID:12023275)
GO_REF:0000107		 RGD
Ensembl		 PMID:12023275 GO_REF:0000107 NCBI chr 1:218,313,455...218,343,263
Ensembl chr 1:208,887,895...208,918,506 		JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase acts_upstream_of_or_within ISO (PMID:25667419) RGD PMID:25667419 NCBI chr10:45,275,434...45,349,651
Ensembl chr10:44,775,911...44,850,013 		JBrowse link
G Sgms1 sphingomyelin synthase 1 involved_in ISO
ISS
IBA
IEA		 (PMID:14685263), (PMID:14976195), (PMID:17982138)
GO_REF:0000024
GO_REF:0000033
(PMID:27892528)
GO_REF:0000107		 RGD
HGNC-UCL
GO_Central
Ensembl		 PMID:14685263 PMID:14976195 PMID:17982138 PMID:27892528 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:239,409,991...239,681,195
Ensembl chr 1:229,998,119...230,259,603 		JBrowse link
G Sgms2 sphingomyelin synthase 2 involved_in
acts_upstream_of_or_within		 ISO
IEA
IBA		 (PMID:14685263), (PMID:17982138)
GO_REF:0000107
GO_REF:0000033
(PMID:25667419)
(PMID:27892528)		 RGD
Ensembl
GO_Central		 PMID:14685263 PMID:17982138 PMID:25667419 PMID:27892528 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:222,567,661...222,641,804
Ensembl chr 2:219,893,572...219,967,546 		JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:3815115 (PMID:16216550)
(PMID:26301690)
GO_REF:0000107		 RGD
Ensembl		 PMID:16216550 PMID:26301690 GO_REF:0000107 NCBI chr17:12,029,189...12,068,234
Ensembl chr17:11,877,249...11,916,295 		JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 acts_upstream_of_or_within ISO
IEA		 MGI:3815117 (PMID:16216550)
GO_REF:0000107		 RGD
Ensembl		 PMID:16216550 GO_REF:0000107 NCBI chr 6:112,679,623...112,762,470
Ensembl chr 6:106,950,949...107,031,542 		JBrowse link
G Vapa VAMP associated protein A involved_in ISO (PMID:12023275) RGD PMID:12023275 NCBI chr 9:112,624,791...112,654,731
Ensembl chr 9:105,177,907...105,207,847 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      metabolic process 12180
        biosynthetic process 8654
          amide biosynthetic process 159
            sphingomyelin biosynthetic process 10
Path 2
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      metabolic process 12180
        primary metabolic process 10745
          lipid metabolic process 1474
            membrane lipid metabolic process 209
              sphingolipid metabolic process 160
                sphingolipid biosynthetic process 103
                  sphingomyelin biosynthetic process 10
paths to the root