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ONTOLOGY REPORT - ANNOTATIONS


Term:sphingomyelin catabolic process
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Accession:GO:0006685 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine.
Synonyms:exact_synonym: sphingomyelin breakdown;   sphingomyelin catabolism;   sphingomyelin degradation



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sphingomyelin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:104,242,223...104,246,589
Ensembl chr10:104,242,223...104,246,589
JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:18815062), (PMID:20807762), (PMID:22573858)
(MGI:5529577|PMID:23973266)
PMID:21873635
RGD PMID:18815062 PMID:20807762 PMID:22573858 PMID:23973266 PMID:21873635 MGI:5529577, RGD:13792537 NCBI chr 1:159,892,946...159,896,789
Ensembl chr 1:159,892,859...159,896,794
JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 acts_upstream_of_or_within ISO (MGI:5529577|PMID:23973266) RGD PMID:23973266 MGI:5529577 NCBI chr20:44,986,229...44,989,343
Ensembl chr20:44,986,231...44,989,441
JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5529577|PMID:23973266)
Ensembl
RGD
PMID:23973266 GO_REF:0000107 MGI:5529577 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749
JBrowse link
G Smpd4 sphingomyelin phosphodiesterase 4 involved_in IBA
ISO
PMID:21873635
(MGI:6450503|PMID:25180167)
(PMID:16517606), (PMID:25180167)
RGD PMID:16517606 PMID:25180167 PMID:21873635 MGI:6450503, RGD:13792537 NCBI chr11:83,362,534...83,386,257
Ensembl chr11:83,362,534...83,386,250
JBrowse link
G Smpd5 sphingomyelin phosphodiesterase 5 involved_in ISO (MGI:6450238|PMID:21183079) RGD PMID:21183079 MGI:6450238 NCBI chr 7:108,009,182...108,011,767
Ensembl chr 7:108,009,173...108,011,763
JBrowse link
G Smpdl3a sphingomyelin phosphodiesterase, acid-like 3A NOT|involved_in ISO
ISS
(PMID:26783088)
GO_REF:0000024
RGD
UniProt
PMID:26783088 GO_REF:0000024 NCBI chr20:37,132,592...37,155,567
Ensembl chr20:37,132,592...37,155,567
JBrowse link
G Smpdl3b sphingomyelin phosphodiesterase, acid-like 3B involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:144,944,618...144,966,703
Ensembl chr 5:144,944,636...144,966,720
JBrowse link
positive regulation of sphingomyelin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISS
ISO
GO_REF:0000024
(MGI:4947032|PMID:21177474)
UniProt
RGD
PMID:21177474 GO_REF:0000024 MGI:4947032 NCBI chr10:104,242,223...104,246,589
Ensembl chr10:104,242,223...104,246,589
JBrowse link
G Prkcd protein kinase C, delta involved_in IEA
ISO
GO_REF:0000107
(PMID:19279011)
Ensembl
RGD
PMID:19279011 GO_REF:0000107 NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19390
    metabolic process 11736
      organic substance metabolic process 11278
        organophosphate metabolic process 932
          phospholipid metabolic process 378
            sphingomyelin metabolic process 18
              sphingomyelin catabolic process 9
                positive regulation of sphingomyelin catabolic process 2
                regulation of sphingomyelin catabolic process + 2
Path 2
Term Annotations click to browse term
  biological_process 19390
    metabolic process 11736
      primary metabolic process 10467
        lipid metabolic process 1365
          cellular lipid metabolic process 1021
            membrane lipid metabolic process 187
              sphingolipid metabolic process 141
                sphingomyelin metabolic process 18
                  sphingomyelin catabolic process 9
                    positive regulation of sphingomyelin catabolic process 2
                    regulation of sphingomyelin catabolic process + 2
paths to the root