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ONTOLOGY REPORT - ANNOTATIONS


Term:sphingomyelin catabolic process
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Accession:GO:0006685 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine.
Synonyms:exact_synonym: sphingomyelin breakdown;   sphingomyelin catabolism;   sphingomyelin degradation



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sphingomyelin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in IEA InterPro
InterPro
GO_REF:0000002 NCBI chr12:2,612,543...2,619,541
Ensembl chr12:2,612,574...2,619,519
JBrowse link
G SMPD1 sphingomyelin phosphodiesterase 1 involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:5529577|PMID:23973266)
GO_Central
Ensembl
UniProt
GO_Central
InterPro
MGI
PMID:21873635 PMID:23973266 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 MGI:5529577 NCBI chr 9:3,324,091...3,328,493
Ensembl chr 9:3,324,091...3,328,373
JBrowse link
G SMPD2 sphingomyelin phosphodiesterase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5529577|PMID:23973266) Ensembl
Ensembl
MGI
PMID:23973266 GO_REF:0000107 MGI:5529577 NCBI chr 1:75,508,303...75,511,572
Ensembl chr 1:75,508,350...75,512,159
JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 acts_upstream_of_or_within ISO (MGI:5529577|PMID:23973266) MGI PMID:23973266 MGI:5529577 NCBI chr 6:28,938,287...29,025,397
Ensembl chr 6:28,938,290...29,025,357
JBrowse link
G SMPD4 sphingomyelin phosphodiesterase 4 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr14:50,663,488...50,689,355
Ensembl chr14:50,663,608...50,689,353
JBrowse link
G SMPD5 sphingomyelin phosphodiesterase 5 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 4:639,228...643,057 JBrowse link
G SMPDL3A sphingomyelin phosphodiesterase acid like 3A involved_in
NOT|involved_in
IEA
ISO
(PMID:26783088) InterPro
InterPro
UniProt
PMID:26783088 GO_REF:0000002 NCBI chr 1:39,848,641...39,869,184
Ensembl chr 1:39,848,641...39,868,731
JBrowse link
G SMPDL3B sphingomyelin phosphodiesterase acid like 3B involved_in IEA InterPro
InterPro
GO_REF:0000002 NCBI chr 6:85,060,639...85,084,483
Ensembl chr 6:85,060,317...85,084,483
JBrowse link
positive regulation of sphingomyelin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISO (MGI:4947032|PMID:21177474) UniProt PMID:21177474 MGI:4947032 NCBI chr12:2,612,543...2,619,541
Ensembl chr12:2,612,574...2,619,519
JBrowse link
G PRKCD protein kinase C delta involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr13:35,290,835...35,323,245
Ensembl chr13:35,290,264...35,323,356
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16975
    metabolic process 10639
      organic substance metabolic process 10191
        organophosphate metabolic process 858
          phospholipid metabolic process 364
            sphingomyelin metabolic process 20
              sphingomyelin catabolic process 9
                positive regulation of sphingomyelin catabolic process 2
                regulation of sphingomyelin catabolic process + 2
Path 2
Term Annotations click to browse term
  biological_process 16975
    metabolic process 10639
      primary metabolic process 9455
        lipid metabolic process 1260
          cellular lipid metabolic process 945
            membrane lipid metabolic process 191
              sphingolipid metabolic process 144
                sphingomyelin metabolic process 20
                  sphingomyelin catabolic process 9
                    positive regulation of sphingomyelin catabolic process 2
                    regulation of sphingomyelin catabolic process + 2
paths to the root