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ONTOLOGY REPORT - ANNOTATIONS


Term:sphingomyelin catabolic process
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Accession:GO:0006685 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine.
Synonyms:exact_synonym: sphingomyelin breakdown;   sphingomyelin catabolism;   sphingomyelin degradation


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sphingomyelin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smpd1 sphingomyelin phosphodiesterase 1 involved_in
acts_upstream_of_or_within
ISO (PMID:18815062), (PMID:20807762), (PMID:22573858)
(MGI:5529577|PMID:23973266)
UniProt
MGI
PMID:18815062 PMID:20807762 PMID:22573858 PMID:23973266 MGI:5529577 NCBI chrNW_004955414:22,117,929...22,121,744
Ensembl chrNW_004955414:22,117,930...22,121,744
JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 acts_upstream_of_or_within ISO (MGI:5529577|PMID:23973266) MGI PMID:23973266 MGI:5529577 NCBI chrNW_004955411:34,481,431...34,484,423
Ensembl chrNW_004955411:34,481,823...34,484,406
JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 acts_upstream_of_or_within ISO (MGI:5529577|PMID:23973266) MGI PMID:23973266 MGI:5529577 NCBI chrNW_004955484:8,207,686...8,298,164
Ensembl chrNW_004955484:8,272,572...8,298,144
JBrowse link
G Smpd4 sphingomyelin phosphodiesterase 4 involved_in ISO (PMID:16517606), (PMID:25180167)
(MGI:6450503|PMID:25180167)
UniProt PMID:16517606 PMID:25180167 MGI:6450503 NCBI chrNW_004955442:19,184,794...19,210,999
Ensembl chrNW_004955442:19,184,794...19,210,999
JBrowse link
G Smpdl3a sphingomyelin phosphodiesterase acid like 3A NOT|involved_in ISO (PMID:26783088) UniProt PMID:26783088 NCBI chrNW_004955436:4,655,730...4,663,993
Ensembl chrNW_004955436:4,655,732...4,663,638
JBrowse link
positive regulation of sphingomyelin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISO (MGI:4947032|PMID:21177474) UniProt PMID:21177474 MGI:4947032 NCBI chrNW_004955506:3,151,133...3,154,613
Ensembl chrNW_004955506:3,151,133...3,154,613
JBrowse link
G Prkcd protein kinase C delta involved_in ISO (PMID:19279011) BHF-UCL PMID:19279011 NCBI chrNW_004955430:3,125,066...3,151,857
Ensembl chrNW_004955430:3,124,738...3,153,274
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12106
    metabolic process 7728
      organic substance metabolic process 7443
        organophosphate metabolic process 656
          phospholipid metabolic process 276
            sphingomyelin metabolic process 17
              sphingomyelin catabolic process 7
                positive regulation of sphingomyelin catabolic process 2
                regulation of sphingomyelin catabolic process + 2
Path 2
Term Annotations click to browse term
  biological_process 12106
    metabolic process 7728
      primary metabolic process 6809
        lipid metabolic process 957
          cellular lipid metabolic process 717
            membrane lipid metabolic process 157
              sphingolipid metabolic process 120
                sphingomyelin metabolic process 17
                  sphingomyelin catabolic process 7
                    positive regulation of sphingomyelin catabolic process 2
                    regulation of sphingomyelin catabolic process + 2
paths to the root