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ONTOLOGY REPORT - ANNOTATIONS

Term:sphingomyelin catabolic process
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Accession:GO:0006685 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine.
Synonyms:exact_synonym: sphingomyelin breakdown;   sphingomyelin catabolism;   sphingomyelin degradation


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sphingomyelin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SMPD1 sphingomyelin phosphodiesterase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23973266) Ensembl
MGI
TreeGrafter
InterPro		 PMID:23973266 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr11:6,521,812...6,526,349 JBrowse link
G SMPD2 sphingomyelin phosphodiesterase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23973266) Ensembl
MGI		 PMID:23973266 GO_REF:0000107 NCBI chr 6:107,243,751...107,246,941
Ensembl chr 6:111,292,130...111,295,408 		JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23973266) Ensembl
MGI		 PMID:23973266 GO_REF:0000107 NCBI chr16:48,734,664...48,825,241
Ensembl chr16:68,131,905...68,142,871 		JBrowse link
G SMPDL3A sphingomyelin phosphodiesterase acid like 3A NOT|involved_in ISO
IEA		 (PMID:26783088) UniProt
InterPro		 PMID:26783088 GO_REF:0000002 NCBI chr 6:120,577,885...120,600,371
Ensembl chr 6:124,701,089...124,726,484 		JBrowse link
G SMPDL3B sphingomyelin phosphodiesterase acid like 3B involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:27,194,502...27,219,454
Ensembl chr 1:28,234,761...28,259,079 		JBrowse link
positive regulation of sphingomyelin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISO (MGI:4947032|PMID:21177474) UniProt PMID:21177474 MGI:4947032 NCBI chr17:73,811,249...73,822,719
Ensembl chr17:79,347,505...79,359,349 		JBrowse link
G PRKCD protein kinase C delta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:53,104,137...53,135,588
Ensembl chr 3:54,330,328...54,357,910 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16313
    metabolic process 10179
      amide metabolic process 410
        sphingomyelin metabolic process 18
          sphingomyelin catabolic process 7
            positive regulation of sphingomyelin catabolic process 2
            regulation of sphingomyelin catabolic process + 2
Path 2
Term Annotations click to browse term
  biological_process 16313
    metabolic process 10179
      primary metabolic process 8792
        lipid metabolic process 1297
          cellular lipid metabolic process 981
            membrane lipid metabolic process 195
              sphingolipid metabolic process 145
                sphingolipid catabolic process 30
                  sphingomyelin catabolic process 7
                    positive regulation of sphingomyelin catabolic process 2
                    regulation of sphingomyelin catabolic process + 2
paths to the root