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ONTOLOGY REPORT - ANNOTATIONS


Term:glucosylceramide metabolic process
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Accession:GO:0006678 term browser browse the term
Definition:The chemical reactions and pathways involving glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group. They are neutral glycolipids containing equimolar amounts of fatty acid, glucose, and sphingosine or a sphingosine derivative.
Synonyms:exact_synonym: glucosylceramide metabolism



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glucosylceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba1 glucosylceramidase beta 1 acts_upstream_of_or_within ISO (PMID:17954912), (PMID:18346921) RGD PMID:17954912 PMID:18346921 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263
JBrowse link
G Psap prosaposin acts_upstream_of_or_within ISO (PMID:17353235) RGD PMID:17353235 NCBI chr20:28,214,229...28,240,501
Ensembl chr20:28,214,271...28,240,498
JBrowse link
glucosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fa2h fatty acid 2-hydroxylase involved_in ISS
ISO
GO_REF:0000024
(PMID:21628453)
UniProt
RGD
PMID:21628453 GO_REF:0000024 NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153
JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase involved_in ISO
IBA
ISS
(PMID:8643456)
(PMID:10430909), (PMID:16109770), (PMID:22851168), (PMID:23748427)
GO_REF:0000033
GO_REF:0000024
RGD
GO_Central
UniProt
PMID:8643456 PMID:10430909 PMID:16109770 PMID:22851168 PMID:23748427 GO_REF:0000024 GO_REF:0000033 NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393
JBrowse link
glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba1 glucosylceramidase beta 1 involved_in ISO
IBA
(PMID:16293621), (PMID:19279011), (PMID:21700325), (PMID:24022302), (PMID:24211208), (PMID:25584808), (PMID:9201993)
(PMID:21700325), (PMID:23707074), (PMID:24211208)
GO_REF:0000033
RGD
GO_Central
PMID:9201993 PMID:16293621 PMID:19279011 PMID:21700325 PMID:23707074 More... GO_REF:0000033 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263
JBrowse link
G Gba2 glucosylceramidase beta 2 involved_in ISO
IEA
ISS
(PMID:17080196), (PMID:30308956)
(PMID:17080196), (PMID:23250757)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:17080196 PMID:23250757 PMID:30308956 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:57,822,389...57,834,522
Ensembl chr 5:57,822,389...57,834,072
JBrowse link
G Gba3 glucosylceramidase beta 3 involved_in
NOT|involved_in
ISO (PMID:17595169), (PMID:26724485)
(PMID:20728381)
RGD PMID:17595169 PMID:20728381 PMID:26724485 NCBI chr14:60,574,974...60,721,411
Ensembl chr14:60,574,976...60,721,653
JBrowse link
positive regulation of glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkcd protein kinase C, delta involved_in ISO
IEA
(PMID:19279011)
GO_REF:0000107
RGD
Ensembl
PMID:19279011 GO_REF:0000107 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
JBrowse link
regulation of glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir127 microRNA 127 acts_upstream_of ISO UniProtKB:P04062 (PMID:25584808) RGD PMID:25584808 NCBI chr 6:128,546,215...128,546,311
Ensembl chr 6:128,546,215...128,546,311
JBrowse link
G Mir16 microRNA 16 acts_upstream_of_or_within ISO UniProtKB:P04062 (PMID:25584808) RGD PMID:25584808 NCBI chr 2:153,245,349...153,245,443
Ensembl chr 2:153,245,349...153,245,443
JBrowse link
G Mir195 microRNA 195 acts_upstream_of_or_within ISO UniProtKB:P04062 (PMID:25584808) RGD PMID:25584808 NCBI chr10:54,951,838...54,951,924
Ensembl chr10:54,951,838...54,951,924
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20217
    cellular process 19275
      metabolic process 12045
        amide metabolic process 460
          ceramide metabolic process 112
            glycosylceramide metabolic process 20
              glucosylceramide metabolic process 10
                glucosylceramide biosynthetic process + 2
                glucosylceramide catabolic process + 7
Path 2
Term Annotations click to browse term
  biological_process 20217
    cellular process 19275
      metabolic process 12045
        primary metabolic process 10671
          lipid metabolic process 1456
            membrane lipid metabolic process 207
              sphingolipid metabolic process 159
                ceramide metabolic process 112
                  glycosylceramide metabolic process 20
                    glucosylceramide metabolic process 10
                      glucosylceramide biosynthetic process + 2
                      glucosylceramide catabolic process + 7
paths to the root