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ONTOLOGY REPORT - ANNOTATIONS

Term:ceramide metabolic process
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Accession:GO:0006672 term browser browse the term
Definition:The chemical reactions and pathways involving ceramides, any N-acylated sphingoid.
Synonyms:exact_synonym: ceramide metabolism

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ceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca12 ATP binding cassette subfamily A member 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936586:1,938,617...2,094,231
Ensembl chrNW_004936586:1,938,617...2,094,279 		JBrowse link
G Acer1 alkaline ceramidase 1 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936588:3,688,244...3,705,831
Ensembl chrNW_004936588:3,688,244...3,705,831 		JBrowse link
G Acer2 alkaline ceramidase 2 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936652:1,289,445...1,329,236
Ensembl chrNW_004936652:1,289,382...1,329,409 		JBrowse link
G Acer3 alkaline ceramidase 3 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936498:5,496,991...5,653,206
Ensembl chrNW_004936498:5,496,991...5,653,206 		JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in IEA UniProt GO_REF:0000117 NCBI chrNW_004936735:2,004,373...2,092,501
Ensembl chrNW_004936735:2,031,844...2,092,347 		JBrowse link
G Cerk ceramide kinase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936629:3,304,236...3,346,264
Ensembl chrNW_004936629:3,304,236...3,344,136 		JBrowse link
G Cert1 ceramide transporter 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19139267) Ensembl
MGI		 PMID:19139267 GO_REF:0000107 NCBI chrNW_004936549:1,261,913...1,368,743
Ensembl chrNW_004936549:1,261,931...1,371,380 		JBrowse link
G Cln8 CLN8 transmembrane ER and ERGIC protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936615:993,092...999,976
Ensembl chrNW_004936615:985,634...1,003,172 		JBrowse link
G Fut7 fucosyltransferase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936669:914,520...920,481
Ensembl chrNW_004936669:919,206...920,341 		JBrowse link
G Htra2 HtrA serine peptidase 2 ISO C2 ceramide RGD PMID:22296759 RGD:5688365 NCBI chrNW_004936556:741,718...746,016
Ensembl chrNW_004936556:741,718...749,090 		JBrowse link
G LOC101955719 sphingomyelin phosphodiesterase 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20378533) Ensembl
MGI		 PMID:20378533 GO_REF:0000107 NCBI chrNW_004936470:8,139,207...8,142,061 JBrowse link
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 involved_in IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936506:8,197,116...8,208,712
Ensembl chrNW_004936506:8,196,784...8,210,584 		JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 involved_in IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936646:280,745...283,488
Ensembl chrNW_004936646:280,661...287,144 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 involved_in IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936490:15,069,435...15,076,112
Ensembl chrNW_004936490:15,069,387...15,076,253 		JBrowse link
G Pla2g15 phospholipase A2 group XV involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11790796) Ensembl
TreeGrafter
MGI		 PMID:11790796 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936475:18,571,599...18,584,977
Ensembl chrNW_004936475:18,571,516...18,585,009 		JBrowse link
G Plpp1 phospholipid phosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936480:12,265,304...12,357,747
Ensembl chrNW_004936480:12,265,246...12,359,450 		JBrowse link
G Plpp2 phospholipid phosphatase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936588:14,422...20,467
Ensembl chrNW_004936588:14,399...20,514 		JBrowse link
G Plpp3 phospholipid phosphatase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936522:4,992,333...5,074,295
Ensembl chrNW_004936522:4,992,322...5,074,313 		JBrowse link
G Psap prosaposin acts_upstream_of_or_within ISO (PMID:15345707)
(PMID:17353235)		 MGI PMID:15345707 PMID:17353235 NCBI chrNW_004936521:6,975,844...7,009,460
Ensembl chrNW_004936521:6,975,770...7,009,136 		JBrowse link
G Sgpl1 sphingosine-1-phosphate lyase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936521:7,850,370...7,899,998
Ensembl chrNW_004936521:7,848,972...7,900,041 		JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23046545) Ensembl
MGI		 PMID:23046545 GO_REF:0000107 NCBI chrNW_004936842:448,315...452,557
Ensembl chrNW_004936842:447,991...452,630 		JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936564:5,565,205...5,568,474
Ensembl chrNW_004936564:5,564,784...5,568,956 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22383528), (PMID:23046545) Ensembl
MGI		 PMID:22383528 PMID:23046545 GO_REF:0000107 NCBI chrNW_004936475:18,667,563...18,755,132
Ensembl chrNW_004936475:18,671,428...18,755,208 		JBrowse link
G Tm9sf2 transmembrane 9 superfamily member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936472:10,946,263...11,006,311
Ensembl chrNW_004936472:10,945,906...11,006,324 		JBrowse link
ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agk acylglycerol kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15252046) Ensembl
TreeGrafter
MGI		 PMID:15252046 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936592:5,454,860...5,531,285
Ensembl chrNW_004936592:5,457,582...5,531,000 		JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936595:1,310,556...1,321,974
Ensembl chrNW_004936595:1,310,534...1,321,985 		JBrowse link
G Aloxe3 arachidonate epidermal lipoxygenase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22832496) Ensembl
MGI		 PMID:22832496 GO_REF:0000107 NCBI chrNW_004936595:1,329,492...1,350,914
Ensembl chrNW_004936595:1,329,435...1,350,923 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936554:104,666...141,761
Ensembl chrNW_004936554:104,229...141,512 		JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936735:2,004,373...2,092,501
Ensembl chrNW_004936735:2,031,844...2,092,347 		JBrowse link
G Cers1 ceramide synthase 1 involved_in IEA Ensembl
TreeGrafter
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chrNW_004936596:2,442,978...2,467,184
Ensembl chrNW_004936596:2,442,991...2,467,184 		JBrowse link
G Cers2 ceramide synthase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15823095) Ensembl
TreeGrafter
MGI
UniProt
InterPro		 PMID:15823095 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chrNW_004936580:1,192,843...1,201,863
Ensembl chrNW_004936580:1,192,847...1,201,909 		JBrowse link
G Cers4 ceramide synthase 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12912983), (PMID:15823095) InterPro
TreeGrafter
MGI
UniProt
Ensembl		 PMID:12912983 PMID:15823095 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chrNW_004936588:5,121,645...5,128,774
Ensembl chrNW_004936588:5,107,663...5,131,140 		JBrowse link
G Cers5 ceramide synthase 5 involved_in IEA InterPro
TreeGrafter
UniProt
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chrNW_004936512:7,780,212...7,809,182
Ensembl chrNW_004936512:7,780,153...7,809,188 		JBrowse link
G Cers6 ceramide synthase 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15823095) InterPro
TreeGrafter
MGI
UniProt
Ensembl		 PMID:15823095 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chrNW_004936469:10,735,327...11,027,019
Ensembl chrNW_004936469:10,740,601...11,027,067 		JBrowse link
G Degs1 delta 4-desaturase, sphingolipid 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:22984457) MGI
TreeGrafter		 PMID:22984457 GO_REF:0000118 NCBI chrNW_004936526:1,149,984...1,153,632 JBrowse link
G Degs2 delta 4-desaturase, sphingolipid 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936604:3,821,672...3,839,975
Ensembl chrNW_004936604:3,817,886...3,839,986 		JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:24,765,173...24,769,903
Ensembl chrNW_004936474:24,764,718...24,769,947 		JBrowse link
G Fa2h fatty acid 2-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:23,625,023...23,675,211
Ensembl chrNW_004936475:23,624,969...23,675,235 		JBrowse link
G Gba1 glucosylceramidase beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936580:4,715,869...4,720,752
Ensembl chrNW_004936580:4,715,408...4,720,798 		JBrowse link
G LOC101955719 sphingomyelin phosphodiesterase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936470:8,139,207...8,142,061 JBrowse link
G LOC101958833 ceramide synthase 3 involved_in IEA InterPro
TreeGrafter
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chrNW_004936483:3,276,519...3,365,054
Ensembl chrNW_004936483:3,206,110...3,229,939
Ensembl chrNW_004936483:3,206,110...3,229,939 		JBrowse link
G LOC101967158 serine palmitoyltransferase 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431)
(PMID:16216550)		 MGI
TreeGrafter
Ensembl		 PMID:16216550 PMID:25691431 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936488:6,313,189...6,404,425
Ensembl chrNW_004936488:6,289,833...6,296,849
Ensembl chrNW_004936488:6,289,833...6,296,849 		JBrowse link
G LOC101977389 cytochrome P450 4F22 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936596:4,987,577...5,006,459
Ensembl chrNW_004936596:4,984,831...5,006,622 		JBrowse link
G Mecr mitochondrial trans-2-enoyl-CoA reductase acts_upstream_of
involved_in		 ISO
IEA		 (PMID:37653044) UniProt
Ensembl		 PMID:37653044 GO_REF:0000107 NCBI chrNW_004936474:13,146,572...13,183,707
Ensembl chrNW_004936474:13,147,938...13,183,770 		JBrowse link
G P2rx1 purinergic receptor P2X 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16325464) Ensembl
MGI		 PMID:16325464 GO_REF:0000107 NCBI chrNW_004936677:530,338...546,742
Ensembl chrNW_004936677:530,330...548,180 		JBrowse link
G P2rx7 purinergic receptor P2X 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16325464) Ensembl
MGI		 PMID:16325464 GO_REF:0000107 NCBI chrNW_004936558:3,106,819...3,149,689
Ensembl chrNW_004936558:3,108,283...3,149,765 		JBrowse link
G Pnpla1 patatin like phospholipase domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:23,066,840...23,100,126
Ensembl chrNW_004936476:23,061,854...23,099,720 		JBrowse link
G Samd8 sterile alpha motif domain containing 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25667419)
(PMID:25605874)
(PMID:25605874), (PMID:25667419)		 Ensembl
TreeGrafter
MGI		 PMID:25605874 PMID:25667419 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936521:4,170,016...4,229,877
Ensembl chrNW_004936521:4,169,979...4,229,890 		JBrowse link
G Sgms1 sphingomyelin synthase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25605874) MGI
TreeGrafter
Ensembl		 PMID:25605874 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936735:1,702,754...1,984,141
Ensembl chrNW_004936735:1,943,352...1,984,141 		JBrowse link
G Sgms2 sphingomyelin synthase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25605874) Ensembl
TreeGrafter
MGI		 PMID:25605874 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936818:687,695...726,123
Ensembl chrNW_004936818:683,659...726,174 		JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 involved_in ISO
IEA		 RGD
TreeGrafter
UniProt
Ensembl		 PMID:17261082 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 RGD:1601344 NCBI chrNW_004936842:448,315...452,557
Ensembl chrNW_004936842:447,991...452,630 		JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 ISO RGD PMID:12473648 RGD:1581395 NCBI chrNW_004936564:5,565,205...5,568,474
Ensembl chrNW_004936564:5,564,784...5,568,956 		JBrowse link
G Smpd4 sphingomyelin phosphodiesterase 4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936619:2,647,880...2,676,371
Ensembl chrNW_004936619:2,647,967...2,676,488 		JBrowse link
G Sptlc1 serine palmitoyltransferase long chain base subunit 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431)
(PMID:16216550)		 MGI
TreeGrafter
Ensembl		 PMID:16216550 PMID:25691431 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936796:886,946...948,254
Ensembl chrNW_004936796:886,922...948,254 		JBrowse link
G Sptlc3 serine palmitoyltransferase long chain base subunit 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936485:6,647,930...6,784,792
Ensembl chrNW_004936485:6,644,188...6,784,828 		JBrowse link
G Sptssa serine palmitoyltransferase small subunit A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431) MGI
TreeGrafter
Ensembl		 PMID:25691431 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936494:8,717,821...8,738,923
Ensembl chrNW_004936494:8,716,829...8,739,066 		JBrowse link
G Sptssb serine palmitoyltransferase small subunit B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:26438849) Ensembl
TreeGrafter
MGI		 PMID:26438849 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936708:1,270,720...1,301,493
Ensembl chrNW_004936708:1,271,190...1,271,420 		JBrowse link
G Tlcd3b TLC domain containing 3B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23275342) Ensembl
TreeGrafter
MGI		 PMID:23275342 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936501:12,435,058...12,450,961
Ensembl chrNW_004936501:12,435,051...12,450,675 		JBrowse link
ceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer1 alkaline ceramidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12783875) Ensembl
TreeGrafter
MGI		 PMID:12783875 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936588:3,688,244...3,705,831
Ensembl chrNW_004936588:3,688,244...3,705,831 		JBrowse link
G Acer2 alkaline ceramidase 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936652:1,289,445...1,329,236
Ensembl chrNW_004936652:1,289,382...1,329,409 		JBrowse link
G Acer3 alkaline ceramidase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936498:5,496,991...5,653,206
Ensembl chrNW_004936498:5,496,991...5,653,206 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936554:104,666...141,761
Ensembl chrNW_004936554:104,229...141,512 		JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936735:2,004,373...2,092,501
Ensembl chrNW_004936735:2,031,844...2,092,347 		JBrowse link
G Cel carboxyl ester lipase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11733511) Ensembl
TreeGrafter
MGI		 PMID:11733511 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936487:19,463,219...19,472,029
Ensembl chrNW_004936487:19,463,182...19,469,900 		JBrowse link
galactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3galt1 beta-1,3-galactosyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936469:11,586,710...12,133,053
Ensembl chrNW_004936469:11,589,492...11,590,472 		JBrowse link
G B3galt2 beta-1,3-galactosyltransferase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936638:1,424,641...1,434,266
Ensembl chrNW_004936638:1,426,044...1,433,660 		JBrowse link
G B4galt3 beta-1,4-galactosyltransferase 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936903:474,789...481,342 JBrowse link
G Fa2h fatty acid 2-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:23,625,023...23,675,211
Ensembl chrNW_004936475:23,624,969...23,675,235 		JBrowse link
G Gal3st1 galactose-3-O-sulfotransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10727929) Ensembl
TreeGrafter
MGI		 PMID:10727929 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936904:142,576...158,606
Ensembl chrNW_004936904:142,387...159,633 		JBrowse link
G LOC101958451 beta-1,4-galactosyltransferase 3-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936777:613,513...614,960 JBrowse link
G Ugt8 UDP glycosyltransferase 8 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936563:5,251,451...5,305,683
Ensembl chrNW_004936563:5,224,173...5,306,120 		JBrowse link
galactosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Galc galactosylceramidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11371512) InterPro
TreeGrafter
MGI
Ensembl		 PMID:11371512 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936488:15,444,184...15,519,395
Ensembl chrNW_004936488:15,444,801...15,518,856 		JBrowse link
G Psap prosaposin acts_upstream_of_or_within ISO (PMID:11371512) MGI PMID:11371512 NCBI chrNW_004936521:6,975,844...7,009,460
Ensembl chrNW_004936521:6,975,770...7,009,136 		JBrowse link
galactosylceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gal3st1 galactose-3-O-sulfotransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936904:142,576...158,606
Ensembl chrNW_004936904:142,387...159,633 		JBrowse link
ganglioside biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3galt4 beta-1,3-galactosyltransferase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:25,587,328...25,589,081
Ensembl chrNW_004936476:25,587,592...25,588,763 		JBrowse link
G B4galnt1 beta-1,4-N-acetyl-galactosaminyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10021458) Ensembl
TreeGrafter
MGI		 PMID:10021458 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936646:1,770,412...1,777,152
Ensembl chrNW_004936646:1,770,930...1,777,173 		JBrowse link
G St6galnac3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936571:3,064,150...3,572,992
Ensembl chrNW_004936571:3,064,179...3,574,202 		JBrowse link
G St6galnac4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936487:15,541,994...15,551,245
Ensembl chrNW_004936487:15,541,735...15,551,305 		JBrowse link
G St6galnac5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936571:3,815,867...3,971,219
Ensembl chrNW_004936571:3,815,823...3,973,328 		JBrowse link
G St6galnac6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10702226) Ensembl
TreeGrafter
MGI		 PMID:10702226 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936487:15,522,286...15,534,934
Ensembl chrNW_004936487:15,522,266...15,539,947 		JBrowse link
G St8sia2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936483:10,278,843...10,343,177
Ensembl chrNW_004936483:10,278,838...10,313,905 		JBrowse link
G St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936497:6,955,973...6,962,952
Ensembl chrNW_004936497:6,955,857...6,963,117 		JBrowse link
G St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936523:3,270,776...3,363,114
Ensembl chrNW_004936523:3,270,718...3,365,668 		JBrowse link
G St8sia6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936520:9,869,166...9,990,205
Ensembl chrNW_004936520:9,869,195...9,988,541 		JBrowse link
ganglioside biosynthetic process via lactosylceramide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galt5 beta-1,4-galactosyltransferase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936514:4,719,198...4,736,638
Ensembl chrNW_004936514:4,719,052...4,736,635 		JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936682:1,535,617...1,590,723
Ensembl chrNW_004936682:1,535,586...1,593,827 		JBrowse link
G LOC101961066 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 involved_in IEA UniProt
TreeGrafter		 GO_REF:0000117 GO_REF:0000118 NCBI chrNW_004936561:5,271,963...5,279,570 JBrowse link
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 involved_in IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chrNW_004936470:15,860,669...15,934,500
Ensembl chrNW_004936470:15,918,749...15,934,503 		JBrowse link
G St3gal2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 involved_in IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chrNW_004936475:23,149,452...23,203,919
Ensembl chrNW_004936475:23,149,487...23,205,027 		JBrowse link
G St3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:25,058,892...25,248,378
Ensembl chrNW_004936474:25,058,892...25,248,378 		JBrowse link
ganglioside catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gm2a GM2 ganglioside activator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9223328) Ensembl
TreeGrafter
MGI
InterPro		 PMID:9223328 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936647:4,126,524...4,140,800
Ensembl chrNW_004936647:4,126,577...4,140,786 		JBrowse link
G Hexa hexosaminidase subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7937929), (PMID:9223328)
(PMID:8789434), (PMID:9645704)		 Ensembl
TreeGrafter
MGI		 PMID:7937929 PMID:8789434 PMID:9223328 PMID:9645704 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936471:31,712,485...31,738,273
Ensembl chrNW_004936471:31,709,491...31,738,245 		JBrowse link
G Hexb hexosaminidase subunit beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10021458), (PMID:12657883), (PMID:12756243), (PMID:15748167), (PMID:9223328)
(PMID:8566348)
(PMID:8789434), (PMID:9645704)		 Ensembl
TreeGrafter
MGI		 PMID:8566348 PMID:8789434 PMID:9223328 PMID:9645704 PMID:10021458 More... GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936549:1,918,482...1,943,665
Ensembl chrNW_004936549:1,917,327...1,943,691 		JBrowse link
G Neu1 neuraminidase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936727:1,683,283...1,687,130
Ensembl chrNW_004936727:1,683,204...1,688,883 		JBrowse link
G Neu2 neuraminidase 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936525:4,177,085...4,179,692
Ensembl chrNW_004936525:4,177,085...4,179,692 		JBrowse link
G Neu3 neuraminidase 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936498:3,897,511...3,915,013
Ensembl chrNW_004936498:3,897,485...3,910,115 		JBrowse link
G Neu4 neuraminidase 4 involved_in ISO (PMID:15213228), (PMID:15847605)
(MGI:4361102|PMID:19506080)		 UniProt PMID:15213228 PMID:15847605 PMID:19506080 MGI:4361102 NCBI chrNW_004936745:172,983...175,470 JBrowse link
ganglioside metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 involved_in ISO (MGI:3718765|PMID:17488728) UniProt PMID:17488728 MGI:3718765 NCBI chrNW_004936669:922,978...941,996
Ensembl chrNW_004936669:926,622...942,167 		JBrowse link
G Cln6 CLN6 transmembrane ER protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:28,069,058...28,084,607
Ensembl chrNW_004936471:28,070,462...28,084,648 		JBrowse link
G Gm2a GM2 ganglioside activator ISO RGD PMID:9770472 RGD:1598995 NCBI chrNW_004936647:4,126,524...4,140,800
Ensembl chrNW_004936647:4,126,577...4,140,786 		JBrowse link
G Itgb8 integrin subunit beta 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16251442) Ensembl
MGI		 PMID:16251442 GO_REF:0000107 NCBI chrNW_004936546:6,352,186...6,447,458
Ensembl chrNW_004936546:6,353,986...6,442,756 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21408219) Ensembl
MGI		 PMID:21408219 GO_REF:0000107 NCBI chrNW_004936490:17,305,033...17,312,167
Ensembl chrNW_004936490:17,304,586...17,314,521 		JBrowse link
glucosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fa2h fatty acid 2-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:23,625,023...23,675,211
Ensembl chrNW_004936475:23,624,969...23,675,235 		JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936559:1,475,684...1,513,273
Ensembl chrNW_004936559:1,475,592...1,513,273 		JBrowse link
glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba1 glucosylceramidase beta 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936580:4,715,869...4,720,752
Ensembl chrNW_004936580:4,715,408...4,720,798 		JBrowse link
G Gba2 glucosylceramidase beta 2 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936524:3,730,833...3,742,526
Ensembl chrNW_004936524:3,730,833...3,742,531 		JBrowse link
glucosylceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba1 glucosylceramidase beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17954912), (PMID:18346921) Ensembl
MGI		 PMID:17954912 PMID:18346921 GO_REF:0000107 NCBI chrNW_004936580:4,715,869...4,720,752
Ensembl chrNW_004936580:4,715,408...4,720,798 		JBrowse link
G Psap prosaposin acts_upstream_of_or_within ISO (PMID:17353235) MGI PMID:17353235 NCBI chrNW_004936521:6,975,844...7,009,460
Ensembl chrNW_004936521:6,975,770...7,009,136 		JBrowse link
glycosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gla galactosidase alpha acts_upstream_of_or_within ISO (PMID:10840053), (PMID:15629890)
(PMID:10841515), (PMID:11752062), (PMID:9122231)		 MGI PMID:9122231 PMID:10840053 PMID:10841515 PMID:11752062 PMID:15629890 NCBI chrNW_004936813:474,938...484,753
Ensembl chrNW_004936813:474,949...484,760 		JBrowse link
G Lct lactase involved_in ISO PMID:4752949 UniProt PMID:4752949 RGD:151356630 NCBI chrNW_004936469:40,064,822...40,108,423
Ensembl chrNW_004936469:40,064,822...40,107,447 		JBrowse link
G LOC101968782 cytosolic beta-glucosidase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936477:6,272,938...6,379,811
Ensembl chrNW_004936477:6,272,938...6,379,811 		JBrowse link
glycosylceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G St6galnac3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936571:3,064,150...3,572,992
Ensembl chrNW_004936571:3,064,179...3,574,202 		JBrowse link
G St6galnac6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936487:15,522,286...15,534,934
Ensembl chrNW_004936487:15,522,266...15,539,947 		JBrowse link
lactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galt4 beta-1,4-galactosyltransferase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936536:6,215,221...6,241,828
Ensembl chrNW_004936536:6,215,152...6,241,877 		JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936682:1,535,617...1,590,723
Ensembl chrNW_004936682:1,535,586...1,593,827 		JBrowse link
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431) MGI
Ensembl		 PMID:25691431 GO_REF:0000107 NCBI chrNW_004936506:8,197,116...8,208,712
Ensembl chrNW_004936506:8,196,784...8,210,584 		JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431) MGI
Ensembl		 PMID:25691431 GO_REF:0000107 NCBI chrNW_004936646:280,745...283,488
Ensembl chrNW_004936646:280,661...287,144 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431) MGI
Ensembl		 PMID:25691431 GO_REF:0000107 NCBI chrNW_004936490:15,069,435...15,076,112
Ensembl chrNW_004936490:15,069,387...15,076,253 		JBrowse link
G Sphk1 sphingosine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936594:1,482,830...1,489,337
Ensembl chrNW_004936594:1,486,111...1,489,188 		JBrowse link
omega-hydroxyceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnpla1 patatin like phospholipase domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:23,066,840...23,100,126
Ensembl chrNW_004936476:23,061,854...23,099,720 		JBrowse link
positive regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn1 cellular communication network factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19364818) Ensembl
MGI		 PMID:19364818 GO_REF:0000107 NCBI chrNW_004936608:152,174...155,123
Ensembl chrNW_004936608:151,838...155,358 		JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISO (MGI:4947032|PMID:21177474) UniProt PMID:21177474 MGI:4947032 NCBI chrNW_004936594:3,855,071...3,864,034
Ensembl chrNW_004936594:3,855,150...3,858,317 		JBrowse link
G Pla2g6 phospholipase A2 group VI involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:18936091 GO_REF:0000118 RGD:6482750 NCBI chrNW_004936492:3,011,752...3,060,962
Ensembl chrNW_004936492:3,011,772...3,060,986 		JBrowse link
G Prkcd protein kinase C delta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936473:3,892,625...3,923,467
Ensembl chrNW_004936473:3,892,366...3,923,515 		JBrowse link
G Sirt3 sirtuin 3 involved_in ISO (MGI:5755322|PMID:26620563) UniProt PMID:26620563 MGI:5755322 NCBI chrNW_004936888:63,131...78,536
Ensembl chrNW_004936888:63,546...77,950 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 ISO RGD PMID:20096352 RGD:10041064 NCBI chrNW_004936475:18,667,563...18,755,132
Ensembl chrNW_004936475:18,671,428...18,755,208 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936664:2,668,708...2,676,608
Ensembl chrNW_004936664:2,669,920...2,676,587 		JBrowse link
G Znf750 zinc finger protein 750 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:37115925) Ensembl
MGI		 PMID:37115925 GO_REF:0000107 NCBI chrNW_004936923:299,725...302,741
Ensembl chrNW_004936923:299,719...307,488 		JBrowse link
positive regulation of glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkcd protein kinase C delta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936473:3,892,625...3,923,467
Ensembl chrNW_004936473:3,892,366...3,923,515 		JBrowse link
regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:31880535) UniProt
MGI
Ensembl		 PMID:31880535 GO_REF:0000104 GO_REF:0000107 GO_REF:0000117 NCBI chrNW_004936506:8,197,116...8,208,712
Ensembl chrNW_004936506:8,196,784...8,210,584 		JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 involved_in IEA UniProt GO_REF:0000104 GO_REF:0000117 NCBI chrNW_004936646:280,745...283,488
Ensembl chrNW_004936646:280,661...287,144 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:31880535) Ensembl
MGI
UniProt		 PMID:31880535 GO_REF:0000104 GO_REF:0000107 GO_REF:0000117 NCBI chrNW_004936490:15,069,435...15,076,112
Ensembl chrNW_004936490:15,069,387...15,076,253 		JBrowse link
G Paqr4 progestin and adipoQ receptor family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936694:1,196,650...1,200,067
Ensembl chrNW_004936694:1,196,527...1,200,091 		JBrowse link
G Prkcd protein kinase C delta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936473:3,892,625...3,923,467
Ensembl chrNW_004936473:3,892,366...3,923,515 		JBrowse link
G Samd8 sterile alpha motif domain containing 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936521:4,170,016...4,229,877
Ensembl chrNW_004936521:4,169,979...4,229,890 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16121
    metabolic process 10243
      amide metabolic process 412
        ceramide metabolic process 104
          ceramide biosynthetic process + 71
          ceramide catabolic process + 21
          ganglioside metabolic process + 27
          glycosylceramide metabolic process + 18
          lactosylceramide metabolic process + 2
Path 2
Term Annotations click to browse term
  biological_process 16121
    metabolic process 10243
      primary metabolic process 9150
        lipid metabolic process 1272
          cellular lipid metabolic process 939
            membrane lipid metabolic process 197
              sphingolipid metabolic process 147
                ceramide metabolic process 104
                  ceramide biosynthetic process + 71
                  ceramide catabolic process + 21
                  ganglioside metabolic process + 27
                  glycosylceramide metabolic process + 18
                  lactosylceramide metabolic process + 2
paths to the root