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ONTOLOGY REPORT - ANNOTATIONS

Term:ceramide metabolic process
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Accession:GO:0006672 term browser browse the term
Definition:The chemical reactions and pathways involving ceramides, any N-acylated sphingoid.
Synonyms:exact_synonym: ceramide metabolism


show annotations for term's descendants           Sort by:
ceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA12 ATP binding cassette subfamily A member 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:117,244,704...117,451,009
Ensembl chr15:117,244,719...117,450,863 		JBrowse link
G ACER1 alkaline ceramidase 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 2:72,704,603...72,767,474
Ensembl chr 2:72,743,643...72,769,570 		JBrowse link
G ACER2 alkaline ceramidase 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:203,387,669...203,415,018
Ensembl chr 1:203,386,791...203,414,972 		JBrowse link
G ACER3 alkaline ceramidase 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr 9:10,985,078...11,167,386
Ensembl chr 9:10,967,857...11,162,502 		JBrowse link
G ASAH2 N-acylsphingosine amidohydrolase 2 involved_in IEA UniProt GO_REF:0000117 NCBI chr14:99,018,111...99,141,374
Ensembl chr14:99,025,005...99,129,100 		JBrowse link
G CERK ceramide kinase involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:2,818,738...2,870,200
Ensembl chr 5:2,818,784...2,870,195 		JBrowse link
G CERT1 ceramide transporter 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19139267) Ensembl
MGI		 PMID:19139267 GO_REF:0000107 NCBI chr 2:84,410,425...84,538,018
Ensembl chr 2:84,413,340...84,537,783 		JBrowse link
G CLN8 CLN8 transmembrane ER and ERGIC protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:33,282,524...33,325,598
Ensembl chr15:33,288,301...33,304,631 		JBrowse link
G FUT7 fucosyltransferase 7 involved_in IEA Ensembl GO_REF:0000107
G HTRA2 HtrA serine peptidase 2 ISO C2 ceramide RGD PMID:22296759 RGD:5688365 NCBI chr 3:68,516,666...68,520,025
Ensembl chr 3:68,516,500...68,519,886 		JBrowse link
G LOC100513844 galactoside 3(4)-L-fucosyltransferase involved_in ISO (PMID:17604274) BHF-UCL PMID:17604274 NCBI chr 2:73,152,451...73,171,616 JBrowse link
G ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 involved_in IEA
IBA		 Ensembl
GO_Central
UniProt		 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 NCBI chr15:94,359,784...94,377,331
Ensembl chr15:94,359,358...94,377,303 		JBrowse link
G ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 involved_in IEA Ensembl
UniProt		 GO_REF:0000104 GO_REF:0000107 NCBI chr 5:21,262,134...21,264,689
Ensembl chr 5:21,262,193...21,264,685 		JBrowse link
G ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 involved_in IEA
IBA		 Ensembl
GO_Central
UniProt		 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 NCBI chr12:22,411,130...22,417,744
Ensembl chr12:22,411,587...22,417,736 		JBrowse link
G PLA2G15 phospholipase A2 group XV involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11790796) Ensembl
MGI		 PMID:11790796 GO_REF:0000107 NCBI chr 6:28,820,620...28,832,768
Ensembl chr 6:28,820,668...28,832,767 		JBrowse link
G PLPP1 phospholipid phosphatase 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr16:34,604,367...34,741,524
Ensembl chr16:34,600,719...34,744,437 		JBrowse link
G PLPP2 phospholipid phosphatase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:77,945,760...77,957,318
Ensembl chr 2:77,945,841...77,957,313 		JBrowse link
G PLPP3 phospholipid phosphatase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:155,800,838...155,894,919
Ensembl chr 6:155,800,678...155,894,912 		JBrowse link
G PSAP prosaposin acts_upstream_of_or_within ISO (PMID:17353235)
(PMID:15345707)		 MGI PMID:15345707 PMID:17353235 NCBI chr14:74,734,185...74,820,645
Ensembl chr14:74,734,189...74,887,763 		JBrowse link
G SGPL1 sphingosine-1-phosphate lyase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:73,696,902...73,781,830
Ensembl chr14:73,724,100...73,781,800 		JBrowse link
G SMPD1 sphingomyelin phosphodiesterase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23046545) Ensembl
MGI		 PMID:23046545 GO_REF:0000107 NCBI chr 9:3,324,091...3,328,493
Ensembl chr 9:3,324,442...3,328,457 		JBrowse link
G SMPD2 sphingomyelin phosphodiesterase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:75,508,303...75,511,572
Ensembl chr 1:75,508,350...75,512,153 		JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22383528), (PMID:23046545) Ensembl
MGI		 PMID:22383528 PMID:23046545 GO_REF:0000107 NCBI chr 6:28,938,287...29,025,397
Ensembl chr 6:28,938,290...29,025,357 		JBrowse link
G SMPD5 sphingomyelin phosphodiesterase 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20378533) Ensembl
MGI		 PMID:20378533 GO_REF:0000107 NCBI chr 4:639,228...643,057 JBrowse link
G TM9SF2 transmembrane 9 superfamily member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:68,407,834...68,469,956
Ensembl chr11:68,404,975...68,469,953 		JBrowse link
ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGK acylglycerol kinase involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:15252046) Ensembl
MGI
GO_Central		 PMID:15252046 GO_REF:0000033 GO_REF:0000107 NCBI chr18:8,263,761...8,369,060
Ensembl chr18:8,263,896...8,368,972 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:53,292,530...53,302,850
Ensembl chr12:53,292,526...53,302,993 		JBrowse link
G ALOXE3 arachidonate lipoxygenase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22832496) Ensembl
MGI		 PMID:22832496 GO_REF:0000107 NCBI chr12:53,309,845...53,331,780
Ensembl chr12:53,309,848...53,331,523 		JBrowse link
G ASAH1 N-acylsphingosine amidohydrolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:5,712,048...5,749,811
Ensembl chr17:5,712,058...5,758,821 		JBrowse link
G ASAH2 N-acylsphingosine amidohydrolase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:99,018,111...99,141,374
Ensembl chr14:99,025,005...99,129,100 		JBrowse link
G CERS2 ceramide synthase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:15823095) Ensembl
MGI
GO_Central
UniProt
InterPro		 PMID:15823095 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr 4:98,250,773...98,260,504
Ensembl chr 4:98,250,964...98,260,427 		JBrowse link
G CERS3 ceramide synthase 3 involved_in IEA InterPro
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 NCBI chr 1:139,027,604...139,154,830
Ensembl chr 1:139,030,642...139,136,874 		JBrowse link
G CERS4 ceramide synthase 4 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:12912983), (PMID:15823095) InterPro
MGI
GO_Central
UniProt
Ensembl		 PMID:12912983 PMID:15823095 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr 2:71,004,418...71,047,968
Ensembl chr 2:71,004,420...71,048,248 		JBrowse link
G CERS5 ceramide synthase 5 involved_in IEA
IBA		 InterPro
GO_Central
UniProt
Ensembl		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr 5:16,038,918...16,070,103
Ensembl chr 5:16,037,747...16,070,007 		JBrowse link
G CERS6 ceramide synthase 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15823095) InterPro
MGI
UniProt
Ensembl		 PMID:15823095 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 NCBI chr15:74,927,088...75,261,558
Ensembl chr15:74,927,130...75,261,554 		JBrowse link
G CYP4F22 cytochrome P450 family 4 subfamily F member 22 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:62,078,403...62,110,891
Ensembl chr 2:62,081,269...62,110,899 		JBrowse link
G DEGS1 delta 4-desaturase, sphingolipid 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 (PMID:22984457) GO_Central
MGI		 PMID:22984457 GO_REF:0000033 NCBI chr10:12,529,021...12,568,447
Ensembl chr10:12,557,767...12,568,978 		JBrowse link
G ELOVL1 ELOVL fatty acid elongase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:167,881,357...167,886,125
Ensembl chr 6:167,881,352...167,886,124 		JBrowse link
G FA2H fatty acid 2-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:12,855,330...12,910,821
Ensembl chr 6:12,855,421...12,910,818 		JBrowse link
G GBA1 glucosylceramidase beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:94,583,905...94,606,689
Ensembl chr 4:94,584,134...94,609,745 		JBrowse link
G GDF1 growth differentiation factor 1 involved_in IEA InterPro
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 NCBI chr 2:58,951,463...58,972,692
Ensembl chr 2:58,951,727...58,974,670 		JBrowse link
G MECR mitochondrial trans-2-enoyl-CoA reductase acts_upstream_of
involved_in		 ISO
IEA		 (PMID:37653044) UniProt
Ensembl		 PMID:37653044 GO_REF:0000107 NCBI chr 6:86,094,383...86,131,691
Ensembl chr 6:86,094,423...86,131,682 		JBrowse link
G P2RX1 purinergic receptor P2X 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16325464) Ensembl
MGI		 PMID:16325464 GO_REF:0000107 NCBI chr12:49,956,329...49,974,789
Ensembl chr12:49,956,327...49,974,671 		JBrowse link
G P2RX7 purinergic receptor P2X 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16325464) Ensembl
MGI		 PMID:16325464 GO_REF:0000107 NCBI chr14:31,415,188...31,476,502
Ensembl chr14:31,415,193...31,476,472 		JBrowse link
G PNPLA1 patatin like phospholipase domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:31,987,596...32,025,673
Ensembl chr 7:31,988,197...32,025,245 		JBrowse link
G SAMD8 sterile alpha motif domain containing 8 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:25605874)
(PMID:25605874), (PMID:25667419)
(PMID:25667419)		 Ensembl
MGI
GO_Central		 PMID:25605874 PMID:25667419 GO_REF:0000033 GO_REF:0000107 NCBI chr14:77,679,287...77,737,657
Ensembl chr14:77,636,149...77,737,654 		JBrowse link
G SGMS1 sphingomyelin synthase 1 acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA		 (PMID:25605874) MGI
GO_Central
Ensembl		 PMID:25605874 GO_REF:0000033 GO_REF:0000107 NCBI chr14:99,147,266...99,458,111
Ensembl chr14:99,147,272...99,185,082 		JBrowse link
G SGMS2 sphingomyelin synthase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:25605874) Ensembl
MGI
GO_Central		 PMID:25605874 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:114,052,726...114,145,946
Ensembl chr 8:114,057,603...114,076,154 		JBrowse link
G SMPD1 sphingomyelin phosphodiesterase 1 involved_in ISO
IBA
IEA		 RGD
GO_Central
Ensembl
UniProt		 PMID:17261082 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 RGD:1601344 NCBI chr 9:3,324,091...3,328,493
Ensembl chr 9:3,324,442...3,328,457 		JBrowse link
G SMPD2 sphingomyelin phosphodiesterase 2 involved_in ISO
IBA		 RGD
GO_Central		 PMID:12473648 GO_REF:0000033 RGD:1581395 NCBI chr 1:75,508,303...75,511,572
Ensembl chr 1:75,508,350...75,512,153 		JBrowse link
G SMPD4 sphingomyelin phosphodiesterase 4 involved_in ISO (MGI:6450503|PMID:25180167)
(PMID:16517606), (PMID:25180167)		 UniProt
BHF-UCL		 PMID:16517606 PMID:25180167 MGI:6450503 NCBI chr14:50,663,488...50,689,355
Ensembl chr14:50,663,608...50,689,352 		JBrowse link
G SMPD5 sphingomyelin phosphodiesterase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:639,228...643,057 JBrowse link
G SPTLC1 serine palmitoyltransferase long chain base subunit 1 acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA		 (PMID:25691431)
(PMID:16216550)		 MGI
GO_Central
Ensembl		 PMID:16216550 PMID:25691431 GO_REF:0000033 GO_REF:0000107 NCBI chr14:3,081,964...3,138,113
Ensembl chr14:3,081,972...3,138,103 		JBrowse link
G SPTLC2 serine palmitoyltransferase long chain base subunit 2 acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA		 (PMID:25691431)
(PMID:16216550)		 MGI
GO_Central
Ensembl		 PMID:16216550 PMID:25691431 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:100,545,360...100,638,973
Ensembl chr 7:100,544,478...100,638,905 		JBrowse link
G SPTLC3 serine palmitoyltransferase long chain base subunit 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr17:21,769,388...21,903,269
Ensembl chr17:21,769,484...21,903,264 		JBrowse link
G SPTSSA serine palmitoyltransferase small subunit A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431) MGI
Ensembl		 PMID:25691431 GO_REF:0000107 NCBI chr 7:65,302,887...65,325,877
Ensembl chr 7:65,302,858...65,326,728 		JBrowse link
G SPTSSB serine palmitoyltransferase small subunit B involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:26438849) Ensembl
MGI
GO_Central		 PMID:26438849 GO_REF:0000033 GO_REF:0000107 NCBI chr13:101,023,238...101,059,917
Ensembl chr13:101,023,812...101,059,885 		JBrowse link
G TLCD3B TLC domain containing 3B involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:23275342) Ensembl
MGI
GO_Central		 PMID:23275342 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:18,224,652...18,231,416
Ensembl chr 3:18,223,875...18,231,844 		JBrowse link
ceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACER1 alkaline ceramidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:12783875) Ensembl
MGI
GO_Central		 PMID:12783875 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:72,704,603...72,767,474
Ensembl chr 2:72,743,643...72,769,570 		JBrowse link
G ACER2 alkaline ceramidase 2 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:203,387,669...203,415,018
Ensembl chr 1:203,386,791...203,414,972 		JBrowse link
G ACER3 alkaline ceramidase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:10,985,078...11,167,386
Ensembl chr 9:10,967,857...11,162,502 		JBrowse link
G ASAH1 N-acylsphingosine amidohydrolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:5,712,048...5,749,811
Ensembl chr17:5,712,058...5,758,821 		JBrowse link
G ASAH2 N-acylsphingosine amidohydrolase 2 involved_in IEA
IBA		 InterPro
GO_Central
Ensembl		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr14:99,018,111...99,141,374
Ensembl chr14:99,025,005...99,129,100 		JBrowse link
G CEL carboxyl ester lipase involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:11733511) Ensembl
MGI
GO_Central		 PMID:11733511 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:272,763,203...272,770,259
Ensembl chr 1:272,763,003...272,770,255 		JBrowse link
galactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3GALT1 beta-1,3-galactosyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:73,772,833...74,340,060
Ensembl chr15:74,335,112...74,339,380 		JBrowse link
G B3GALT2 beta-1,3-galactosyltransferase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:613,464...623,587
Ensembl chr10:613,608...624,131 		JBrowse link
G B4GALT3 beta-1,4-galactosyltransferase 3 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:89,278,256...89,284,407
Ensembl chr 4:89,278,439...89,284,400 		JBrowse link
G FA2H fatty acid 2-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:12,855,330...12,910,821
Ensembl chr 6:12,855,421...12,910,818 		JBrowse link
G GAL3ST1 galactose-3-O-sulfotransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:10727929) Ensembl
MGI
GO_Central		 PMID:10727929 GO_REF:0000033 GO_REF:0000107 NCBI chr14:47,455,089...47,476,459
Ensembl chr14:47,457,787...47,476,455 		JBrowse link
G UGT8 UDP glycosyltransferase 8 involved_in ISO PMID:8713090 UniProt PMID:8713090 RGD:39458006 NCBI chr 8:108,233,134...108,315,284
Ensembl chr 8:108,233,143...108,314,921 		JBrowse link
galactosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GALC galactosylceramidase involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:11371512) InterPro
MGI
GO_Central
Ensembl		 PMID:11371512 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:109,894,576...109,961,407
Ensembl chr 7:109,894,578...109,961,413 		JBrowse link
G GBA3 glucosylceramidase beta 3 involved_in ISO (PMID:17595169) UniProt PMID:17595169 NCBI chr 8:16,897,275...17,012,886
Ensembl chr 8:16,897,288...17,044,570 		JBrowse link
G PSAP prosaposin acts_upstream_of_or_within ISO (PMID:11371512) MGI PMID:11371512 NCBI chr14:74,734,185...74,820,645
Ensembl chr14:74,734,189...74,887,763 		JBrowse link
galactosylceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GAL3ST1 galactose-3-O-sulfotransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:47,455,089...47,476,459
Ensembl chr14:47,457,787...47,476,455 		JBrowse link
ganglioside biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3GALT4 beta-1,3-galactosyltransferase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:29,643,049...29,644,847
Ensembl chr 7:29,643,182...29,648,604 		JBrowse link
G B4GALNT1 beta-1,4-N-acetyl-galactosaminyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:10021458) Ensembl
MGI
GO_Central		 PMID:10021458 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:22,889,654...22,897,386
Ensembl chr 5:22,889,656...22,897,508 		JBrowse link
G ST6GALNAC3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:136,633,410...137,201,213
Ensembl chr 6:136,633,441...137,201,252 		JBrowse link
G ST6GALNAC4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:268,391,851...268,402,449
Ensembl chr 1:268,391,855...268,402,407 		JBrowse link
G ST6GALNAC6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 acts_upstream_of_or_within ISO (PMID:10702226) MGI PMID:10702226 NCBI chr 1:268,371,569...268,383,559 JBrowse link
G ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:86,450,302...86,514,232
Ensembl chr 7:86,446,149...86,514,393 		JBrowse link
G ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:106,683,536...106,701,165
Ensembl chr 1:106,683,562...106,696,300 		JBrowse link
G ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:106,754,831...106,845,806
Ensembl chr 2:106,754,701...106,845,830 		JBrowse link
G ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:43,601,677...43,755,154
Ensembl chr10:43,602,908...43,755,277 		JBrowse link
ganglioside biosynthetic process via lactosylceramide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4GALT5 beta-1,4-galactosyltransferase 5 involved_in ISS UniProt GO_REF:0000024 NCBI chr17:51,257,273...51,334,566
Ensembl chr17:51,259,813...51,334,020 		JBrowse link
G B4GALT6 beta-1,4-galactosyltransferase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:115,525,515...115,593,265
Ensembl chr 6:115,524,636...115,593,270 		JBrowse link
G ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:7,814,492...7,911,053
Ensembl chr 4:7,896,554...7,909,505 		JBrowse link
G ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:13,402,336...13,456,495
Ensembl chr 6:13,402,345...13,419,378 		JBrowse link
G ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:167,363,348...167,596,892
Ensembl chr 6:167,363,347...167,595,835 		JBrowse link
ganglioside catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GM2A ganglioside GM2 activator involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:9223328) Ensembl
MGI
GO_Central
InterPro		 PMID:9223328 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr16:71,742,090...71,767,872
Ensembl chr16:71,742,090...71,754,884 		JBrowse link
G HEXA hexosaminidase subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:7937929), (PMID:9223328)
(PMID:8789434), (PMID:9645704)		 Ensembl
MGI
GO_Central		 PMID:7937929 PMID:8789434 PMID:9223328 PMID:9645704 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:60,878,531...60,911,537
Ensembl chr 7:60,878,284...60,913,339 		JBrowse link
G HEXB hexosaminidase subunit beta involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
ISS		 (PMID:8566348)
(PMID:10021458), (PMID:12657883), (PMID:12756243), (PMID:15748167), (PMID:9223328)
(PMID:8789434), (PMID:9645704)		 Ensembl
MGI
GO_Central
UniProt		 PMID:8566348 PMID:8789434 PMID:9223328 PMID:9645704 PMID:10021458 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:83,745,263...83,784,762
Ensembl chr 2:83,744,627...83,784,759 		JBrowse link
G NEU1 neuraminidase 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:23,953,721...23,958,659
Ensembl chr 7:23,947,061...23,958,666 		JBrowse link
G NEU2 neuraminidase 2 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr15:133,392,559...133,479,406
Ensembl chr15:133,468,293...133,477,110 		JBrowse link
G NEU3 neuraminidase 3 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:9,315,263...9,333,878
Ensembl chr 9:9,315,334...9,334,918 		JBrowse link
G NEU4 neuraminidase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:140,324,087...140,332,226
Ensembl chr15:140,325,135...140,328,276 		JBrowse link
ganglioside metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 involved_in ISO (MGI:3718765|PMID:17488728) UniProt PMID:17488728 MGI:3718765
G CLN6 CLN6 transmembrane ER protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:166,107,895...166,126,054
Ensembl chr 1:166,107,228...166,126,808 		JBrowse link
G GM2A ganglioside GM2 activator ISO RGD PMID:9770472 RGD:1598995 NCBI chr16:71,742,090...71,767,872
Ensembl chr16:71,742,090...71,754,884 		JBrowse link
G ITGB8 integrin subunit beta 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16251442) Ensembl
MGI		 PMID:16251442 GO_REF:0000107 NCBI chr 9:89,342,245...89,450,701
Ensembl chr 9:89,341,162...89,448,665 		JBrowse link
G NAGLU N-acetyl-alpha-glucosaminidase involved_in IEA Ensembl GO_REF:0000107 Ensembl chr12:20,271,351...20,279,777 JBrowse link
glucosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FA2H fatty acid 2-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:12,855,330...12,910,821
Ensembl chr 6:12,855,421...12,910,818 		JBrowse link
G UGCG UDP-glucose ceramide glucosyltransferase involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:252,651,850...252,690,817
Ensembl chr 1:252,651,879...252,688,550 		JBrowse link
glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GBA1 glucosylceramidase beta 1 involved_in IEA
IBA
ISS		 Ensembl
GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:94,583,905...94,606,689
Ensembl chr 4:94,584,134...94,609,745 		JBrowse link
G GBA2 glucosylceramidase beta 2 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 1:236,456,238...236,467,887
Ensembl chr 1:236,455,240...236,468,210 		JBrowse link
G GBA3 glucosylceramidase beta 3 involved_in
NOT|involved_in		 ISO (PMID:17595169)
(PMID:20728381)
(PMID:26724485)		 UniProt PMID:17595169 PMID:20728381 PMID:26724485 NCBI chr 8:16,897,275...17,012,886
Ensembl chr 8:16,897,288...17,044,570 		JBrowse link
glucosylceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GBA1 glucosylceramidase beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17954912), (PMID:18346921) Ensembl
MGI		 PMID:17954912 PMID:18346921 GO_REF:0000107 NCBI chr 4:94,583,905...94,606,689
Ensembl chr 4:94,584,134...94,609,745 		JBrowse link
G PSAP prosaposin acts_upstream_of_or_within ISO (PMID:17353235) MGI PMID:17353235 NCBI chr14:74,734,185...74,820,645
Ensembl chr14:74,734,189...74,887,763 		JBrowse link
glycosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GBA3 glucosylceramidase beta 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 8:16,897,275...17,012,886
Ensembl chr 8:16,897,288...17,044,570 		JBrowse link
G GLA galactosidase alpha acts_upstream_of_or_within ISO (PMID:10840053), (PMID:15629890)
(PMID:10841515), (PMID:11752062), (PMID:9122231)		 MGI PMID:9122231 PMID:10840053 PMID:10841515 PMID:11752062 PMID:15629890 NCBI chr  X:83,024,582...83,032,273
Ensembl chr  X:83,023,903...83,032,570 		JBrowse link
G LOC100625897 lactase-phlorizin hydrolase involved_in ISO PMID:4752949 UniProt PMID:4752949 RGD:151356630 NCBI chr15:16,094,277...16,154,467 JBrowse link
glycosylceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ST6GALNAC3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:136,633,410...137,201,213
Ensembl chr 6:136,633,441...137,201,252 		JBrowse link
G ST6GALNAC6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 involved_in ISO (PMID:17123352) BHF-UCL PMID:17123352 NCBI chr 1:268,371,569...268,383,559 JBrowse link
lactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4GALT4 beta-1,4-galactosyltransferase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:140,969,561...141,003,936
Ensembl chr13:140,969,602...141,003,929 		JBrowse link
G B4GALT6 beta-1,4-galactosyltransferase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:115,525,515...115,593,265
Ensembl chr 6:115,524,636...115,593,270 		JBrowse link
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431) MGI
Ensembl		 PMID:25691431 GO_REF:0000107 NCBI chr15:94,359,784...94,377,331
Ensembl chr15:94,359,358...94,377,303 		JBrowse link
G ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431) MGI
Ensembl		 PMID:25691431 GO_REF:0000107 NCBI chr 5:21,262,134...21,264,689
Ensembl chr 5:21,262,193...21,264,685 		JBrowse link
G ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431) MGI
Ensembl		 PMID:25691431 GO_REF:0000107 NCBI chr12:22,411,130...22,417,744
Ensembl chr12:22,411,587...22,417,736 		JBrowse link
G SPHK1 sphingosine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:5,114,946...5,122,580
Ensembl chr12:5,114,947...5,120,083 		JBrowse link
omega-hydroxyceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PNPLA1 patatin like phospholipase domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:31,987,596...32,025,673
Ensembl chr 7:31,988,197...32,025,245 		JBrowse link
positive regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCN1 cellular communication network factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19364818) Ensembl
MGI		 PMID:19364818 GO_REF:0000107 NCBI chr 4:130,392,404...130,395,179
Ensembl chr 4:130,392,407...130,395,150 		JBrowse link
G ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISO (MGI:4947032|PMID:21177474) UniProt PMID:21177474 MGI:4947032 NCBI chr12:2,612,543...2,619,541
Ensembl chr12:2,612,574...2,619,519 		JBrowse link
G PLA2G6 phospholipase A2 group VI involved_in ISO
IBA		 RGD
GO_Central		 PMID:18936091 GO_REF:0000033 RGD:6482750 NCBI chr 5:9,713,809...9,777,921
Ensembl chr 5:9,713,873...9,777,918 		JBrowse link
G PRKCD protein kinase C delta involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:35,290,835...35,323,245
Ensembl chr13:35,290,610...35,323,356 		JBrowse link
G SIRT3 sirtuin 3 involved_in ISO (MGI:5755322|PMID:26620563) UniProt PMID:26620563 MGI:5755322 NCBI chr 2:38,465...55,074
Ensembl chr 2:38,464...55,101 		JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 ISO RGD PMID:20096352 RGD:10041064 NCBI chr 6:28,938,287...29,025,397
Ensembl chr 6:28,938,290...29,025,357 		JBrowse link
G SPHK2 sphingosine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:53,982,911...53,986,779
Ensembl chr 6:53,979,012...53,986,768 		JBrowse link
G ZNF750 zinc finger protein 750 acts_upstream_of_or_within ISO (PMID:37115925) MGI PMID:37115925 NCBI chr12:398,498...407,812 JBrowse link
positive regulation of glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKCD protein kinase C delta involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:35,290,835...35,323,245
Ensembl chr13:35,290,610...35,323,356 		JBrowse link
regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:31880535) UniProt
MGI
Ensembl		 PMID:31880535 GO_REF:0000104 GO_REF:0000107 GO_REF:0000117 NCBI chr15:94,359,784...94,377,331
Ensembl chr15:94,359,358...94,377,303 		JBrowse link
G ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 involved_in IEA UniProt GO_REF:0000104 GO_REF:0000117 NCBI chr 5:21,262,134...21,264,689
Ensembl chr 5:21,262,193...21,264,685 		JBrowse link
G ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:31880535) Ensembl
MGI
UniProt		 PMID:31880535 GO_REF:0000104 GO_REF:0000107 GO_REF:0000117 NCBI chr12:22,411,130...22,417,744
Ensembl chr12:22,411,587...22,417,736 		JBrowse link
G PAQR4 progestin and adipoQ receptor family member 4 involved_in ISO (PMID:32291319), (PMID:38961186) UniProt PMID:32291319 PMID:38961186 NCBI chr 3:39,206,077...39,213,324 JBrowse link
G PRKCD protein kinase C delta involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:35,290,835...35,323,245
Ensembl chr13:35,290,610...35,323,356 		JBrowse link
G SAMD8 sterile alpha motif domain containing 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:77,679,287...77,737,657
Ensembl chr14:77,636,149...77,737,654 		JBrowse link
regulation of glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR127 microRNA mir-127 acts_upstream_of ISO (PMID:25584808) ARUK-UCL PMID:25584808 NCBI chr 7:121,709,636...121,709,715
Ensembl chr 7:121,709,640...121,709,720 		JBrowse link
G MIR16-1 microRNA mir-16-1 acts_upstream_of_or_within ISO (PMID:25584808) ARUK-UCL PMID:25584808 NCBI chr13:100,083,329...100,083,405
Ensembl chr13:100,083,329...100,083,405 		JBrowse link
G MIR16-2 microRNA mir-16-2 acts_upstream_of_or_within ISO (PMID:25584808) ARUK-UCL PMID:25584808 NCBI chr11:17,757,606...17,757,684
Ensembl chr11:17,757,601...17,757,687 		JBrowse link
G MIR195 microRNA mir-195 acts_upstream_of_or_within ISO (PMID:25584808) ARUK-UCL PMID:25584808 NCBI chr12:52,422,039...52,422,118
Ensembl chr12:52,422,039...52,422,118 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17633
    metabolic process 10708
      amide metabolic process 415
        ceramide metabolic process 105
          ceramide biosynthetic process + 67
          ceramide catabolic process + 25
          ganglioside metabolic process + 25
          glycosylceramide metabolic process + 21
          lactosylceramide metabolic process + 2
Path 2
Term Annotations click to browse term
  biological_process 17633
    metabolic process 10708
      primary metabolic process 9434
        lipid metabolic process 1307
          cellular lipid metabolic process 964
            membrane lipid metabolic process 202
              sphingolipid metabolic process 147
                ceramide metabolic process 105
                  ceramide biosynthetic process + 67
                  ceramide catabolic process + 25
                  ganglioside metabolic process + 25
                  glycosylceramide metabolic process + 21
                  lactosylceramide metabolic process + 2
paths to the root