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ONTOLOGY REPORT - ANNOTATIONS

Term:ceramide metabolic process
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Accession:GO:0006672 term browser browse the term
Definition:The chemical reactions and pathways involving ceramides, any N-acylated sphingoid.
Synonyms:exact_synonym: ceramide metabolism

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ceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca12 ATP binding cassette subfamily A member 12 involved_in ISO (PMID:17927575)
(MGI:4462766|PMID:20489143)		 UniProt PMID:17927575 PMID:20489143 MGI:4462766 NCBI chrNW_004624765:1,009,883...1,198,225
Ensembl chrNW_004624765:1,010,287...1,197,910 		JBrowse link
G Acer1 alkaline ceramidase 1 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624828:4,022,288...4,046,235
Ensembl chrNW_004624828:4,041,875...4,045,675 		JBrowse link
G Acer2 alkaline ceramidase 2 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624736:23,363,806...23,556,247
Ensembl chrNW_004624736:23,363,983...23,411,100 		JBrowse link
G Acer3 alkaline ceramidase 3 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624863:37,148...96,550
Ensembl chrNW_004624863:37,148...95,211 		JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in IEA UniProt GO_REF:0000117 NCBI chrNW_004624791:12,906,908...13,059,033
Ensembl chrNW_004624791:12,907,485...13,059,005 		JBrowse link
G Cerk ceramide kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624752:3,285,649...3,328,131
Ensembl chrNW_004624752:3,285,637...3,326,738 		JBrowse link
G Cert1 ceramide transporter 1 acts_upstream_of_or_within ISO (PMID:19139267) MGI PMID:19139267 NCBI chrNW_004624951:718,380...828,220
Ensembl chrNW_004624951:721,411...828,150 		JBrowse link
G Cln8 CLN8 transmembrane ER and ERGIC protein involved_in ISO (PMID:16086686) UniProt PMID:16086686 NCBI chrNW_004624861:960,643...977,292
Ensembl chrNW_004624861:968,219...977,467 		JBrowse link
G Fut5 fucosyltransferase 5 involved_in ISO (PMID:17604274), (PMID:7721776), (PMID:9737988) BHF-UCL PMID:7721776 PMID:9737988 PMID:17604274 NCBI chrNW_004624828:4,343,663...4,348,562 JBrowse link
G Fut7 fucosyltransferase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624760:876,048...877,984
Ensembl chrNW_004624760:876,059...877,574 		JBrowse link
G Htra2 HtrA serine peptidase 2 ISO C2 ceramide RGD PMID:22296759 RGD:5688365 NCBI chrNW_004624749:28,980,375...28,983,719
Ensembl chrNW_004624749:28,980,362...28,983,869 		JBrowse link
G LOC101706228 ORM1-like protein 1 involved_in IEA TreeGrafter
UniProt		 GO_REF:0000104 GO_REF:0000118 NCBI chrNW_004624753:15,730,590...15,731,228 JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 involved_in IEA TreeGrafter
UniProt		 GO_REF:0000104 GO_REF:0000118 NCBI chrNW_004624802:12,197,114...12,200,044
Ensembl chrNW_004624802:12,197,114...12,199,983 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 involved_in IEA TreeGrafter
UniProt		 GO_REF:0000104 GO_REF:0000118 NCBI chrNW_004624795:3,210,382...3,216,130
Ensembl chrNW_004624795:3,209,605...3,217,539 		JBrowse link
G Pla2g15 phospholipase A2 group XV acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:11790796) MGI
TreeGrafter		 PMID:11790796 GO_REF:0000118 NCBI chrNW_004624746:18,048,370...18,063,297
Ensembl chrNW_004624746:18,048,246...18,063,291 		JBrowse link
G Plpp1 phospholipid phosphatase 1 involved_in ISO (MGI:6383560|PMID:10359651)
PMID:8663293
(PMID:9305923), (PMID:9705349)		 UniProt PMID:8663293 PMID:9305923 PMID:9705349 PMID:10359651 MGI:6383560 RGD:15090855 RGD:15090857 NCBI chrNW_004624759:3,780,904...3,868,867
Ensembl chrNW_004624759:3,780,826...3,868,869 		JBrowse link
G Plpp2 phospholipid phosphatase 2 involved_in ISO (PMID:9705349) UniProt PMID:9705349 NCBI chrNW_004624828:8,058,688...8,062,679
Ensembl chrNW_004624828:8,058,329...8,062,677 		JBrowse link
G Plpp3 phospholipid phosphatase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624862:3,550,498...3,627,061
Ensembl chrNW_004624862:3,550,968...3,627,058 		JBrowse link
G Psap prosaposin acts_upstream_of_or_within ISO (PMID:17353235)
(PMID:15345707)		 MGI PMID:15345707 PMID:17353235 NCBI chrNW_004624754:5,725,697...5,753,575
Ensembl chrNW_004624754:5,726,681...5,753,575 		JBrowse link
G Sgpl1 sphingosine-1-phosphate lyase 1 involved_in ISO (PMID:14570870) UniProt PMID:14570870 NCBI chrNW_004624754:4,844,472...4,889,006
Ensembl chrNW_004624754:4,844,552...4,886,709 		JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23046545) Ensembl
MGI		 PMID:23046545 GO_REF:0000107 NCBI chrNW_004624817:7,909,777...7,913,419
Ensembl chrNW_004624817:7,909,468...7,913,417 		JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 involved_in ISO (PMID:9520418) MGI PMID:9520418 NCBI chrNW_004624916:697,861...701,015
Ensembl chrNW_004624916:697,006...701,012 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22383528), (PMID:23046545) Ensembl
MGI		 PMID:22383528 PMID:23046545 GO_REF:0000107 NCBI chrNW_004624746:17,857,779...17,948,469
Ensembl chrNW_004624746:17,920,835...17,948,468 		JBrowse link
G Tm9sf2 transmembrane 9 superfamily member 2 involved_in ISO (PMID:30660999) UniProt PMID:30660999 NCBI chrNW_004624793:11,515,047...11,644,073
Ensembl chrNW_004624793:11,511,446...11,579,008 		JBrowse link
ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agk acylglycerol kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15252046) TreeGrafter
MGI		 PMID:15252046 GO_REF:0000118 NCBI chrNW_004624765:21,572,797...21,666,424
Ensembl chrNW_004624765:21,572,714...21,668,516 		JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624786:10,647,450...10,659,301
Ensembl chrNW_004624786:10,647,175...10,659,337 		JBrowse link
G Aloxe3 arachidonate epidermal lipoxygenase 3 acts_upstream_of_or_within
involved_in		 ISO (PMID:22832496)
(MGI:5488571|PMID:22832496)		 MGI
UniProt		 PMID:22832496 MGI:5488571 NCBI chrNW_004624786:10,666,255...10,689,204
Ensembl chrNW_004624786:10,666,423...10,688,376 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 involved_in ISO (PMID:12764132), (PMID:12815059) UniProt PMID:12764132 PMID:12815059 NCBI chrNW_004624769:21,112,705...21,140,004
Ensembl chrNW_004624769:21,112,851...21,138,831 		JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in ISO (PMID:17475390)
PMID:15123644
(MGI:6274955|PMID:21613224)
PMID:11278489
(PMID:11278489)		 UniProt PMID:11278489 PMID:15123644 PMID:17475390 PMID:21613224 MGI:6274955 RGD:13838793 RGD:13838803 NCBI chrNW_004624791:12,906,908...13,059,033
Ensembl chrNW_004624791:12,907,485...13,059,005 		JBrowse link
G Cers1 ceramide synthase 1 involved_in IEA TreeGrafter
InterPro
UniProt		 GO_REF:0000002 GO_REF:0000117 GO_REF:0000118 NCBI chrNW_004624908:1,937,007...1,949,780
Ensembl chrNW_004624908:1,941,393...1,949,760 		JBrowse link
G Cers2 ceramide synthase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15823095) TreeGrafter
MGI
UniProt
InterPro		 PMID:15823095 GO_REF:0000002 GO_REF:0000117 GO_REF:0000118 NCBI chrNW_004624772:18,851,681...18,855,267
Ensembl chrNW_004624772:18,851,612...18,855,255 		JBrowse link
G Cers3 ceramide synthase 3 involved_in IEA TreeGrafter
InterPro
UniProt		 GO_REF:0000002 GO_REF:0000117 GO_REF:0000118 NCBI chrNW_004624768:4,150,680...4,287,741
Ensembl chrNW_004624768:4,151,925...4,288,195 		JBrowse link
G Cers4 ceramide synthase 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12912983), (PMID:15823095) TreeGrafter
MGI
UniProt
InterPro		 PMID:12912983 PMID:15823095 GO_REF:0000002 GO_REF:0000117 GO_REF:0000118 NCBI chrNW_004624828:1,074,920...1,092,607
Ensembl chrNW_004624828:1,074,942...1,092,647 		JBrowse link
G Cers5 ceramide synthase 5 involved_in IEA TreeGrafter
UniProt
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chrNW_004624816:2,150,409...2,190,099
Ensembl chrNW_004624816:2,150,535...2,182,141 		JBrowse link
G Cers6 ceramide synthase 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15823095) TreeGrafter
UniProt
InterPro
MGI		 PMID:15823095 GO_REF:0000002 GO_REF:0000117 GO_REF:0000118 NCBI chrNW_004624787:6,208,976...6,511,575
Ensembl chrNW_004624787:6,208,478...6,511,708 		JBrowse link
G Degs1 delta 4-desaturase, sphingolipid 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22984457) TreeGrafter
MGI		 PMID:22984457 GO_REF:0000118 NCBI chrNW_004624835:5,880,855...5,889,295
Ensembl chrNW_004624835:5,880,301...5,889,294 		JBrowse link
G Degs2 delta 4-desaturase, sphingolipid 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624734:3,913,159...3,925,309
Ensembl chrNW_004624734:3,913,169...3,926,156 		JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 involved_in ISO (MGI:5532629|PMID:23689133) UniProt PMID:23689133 MGI:5532629 NCBI chrNW_004624892:2,679,872...2,684,499
Ensembl chrNW_004624892:2,675,421...2,684,622 		JBrowse link
G Fa2h fatty acid 2-hydroxylase involved_in ISO (MGI:6245295|PMID:22517924)
(PMID:15337768)		 UniProt PMID:15337768 PMID:22517924 MGI:6245295 NCBI chrNW_004624746:12,125,709...12,186,254
Ensembl chrNW_004624746:12,125,506...12,186,671 		JBrowse link
G Gba1 glucosylceramidase beta 1 involved_in ISO (PMID:19279011) BHF-UCL PMID:19279011 NCBI chrNW_004624885:2,315,371...2,321,327
Ensembl chrNW_004624885:2,315,142...2,321,327 		JBrowse link
G LOC101706763 cytochrome P450 4F22 involved_in ISO (PMID:26056268) UniProt PMID:26056268 NCBI chrNW_004624901:2,596,387...2,619,965
Ensembl chrNW_004624901:2,597,093...2,619,115 		JBrowse link
G Mecr mitochondrial trans-2-enoyl-CoA reductase acts_upstream_of
involved_in		 ISO
IEA		 (PMID:37653044) UniProt
Ensembl		 PMID:37653044 GO_REF:0000107 NCBI chrNW_004624764:12,954,673...12,989,711
Ensembl chrNW_004624764:12,954,115...12,989,755 		JBrowse link
G P2rx1 purinergic receptor P2X 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16325464) Ensembl
MGI		 PMID:16325464 GO_REF:0000107 NCBI chrNW_004624786:6,503,367...6,520,802
Ensembl chrNW_004624786:6,504,250...6,521,821 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:16325464) MGI PMID:16325464 NCBI chrNW_004624747:21,725,813...21,768,123
Ensembl chrNW_004624747:21,725,395...21,759,453 		JBrowse link
G Pnpla1 patatin like phospholipase domain containing 1 involved_in ISO (PMID:27751867)
(MGI:5882269|PMID:27751867)		 UniProt PMID:27751867 MGI:5882269 NCBI chrNW_004624754:21,370,872...21,410,804
Ensembl chrNW_004624754:21,375,463...21,410,961 		JBrowse link
G Samd8 sterile alpha motif domain containing 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25605874)
(PMID:25667419)
(PMID:25605874), (PMID:25667419)		 TreeGrafter
MGI		 PMID:25605874 PMID:25667419 GO_REF:0000118 NCBI chrNW_004624754:8,466,049...8,553,721
Ensembl chrNW_004624754:8,465,981...8,550,666 		JBrowse link
G Sgms1 sphingomyelin synthase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25605874) MGI
TreeGrafter		 PMID:25605874 GO_REF:0000118 NCBI chrNW_004624791:13,096,268...13,490,220
Ensembl chrNW_004624791:13,097,808...13,146,544 		JBrowse link
G Sgms2 sphingomyelin synthase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25605874) TreeGrafter
MGI		 PMID:25605874 GO_REF:0000118 NCBI chrNW_004624830:1,498,700...1,543,112
Ensembl chrNW_004624830:1,502,336...1,542,134 		JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 involved_in ISO
IEA		 RGD
UniProt
Ensembl
TreeGrafter		 PMID:17261082 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 RGD:1601344 NCBI chrNW_004624817:7,909,777...7,913,419
Ensembl chrNW_004624817:7,909,468...7,913,417 		JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 ISO RGD PMID:12473648 RGD:1581395 NCBI chrNW_004624916:697,861...701,015
Ensembl chrNW_004624916:697,006...701,012 		JBrowse link
G Smpd4 sphingomyelin phosphodiesterase 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624945:566,203...592,254 JBrowse link
G Sptlc1 serine palmitoyltransferase long chain base subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16216550)
(PMID:25691431)		 TreeGrafter
MGI		 PMID:16216550 PMID:25691431 GO_REF:0000118 NCBI chrNW_004624868:317,992...393,776
Ensembl chrNW_004624868:318,059...393,773 		JBrowse link
G Sptlc2 serine palmitoyltransferase long chain base subunit 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431)
(PMID:16216550)		 MGI
TreeGrafter		 PMID:16216550 PMID:25691431 GO_REF:0000118 NCBI chrNW_004624734:24,281,482...24,400,870 JBrowse link
G Sptlc3 serine palmitoyltransferase long chain base subunit 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624741:13,956,688...14,152,127
Ensembl chrNW_004624741:13,956,570...14,152,600 		JBrowse link
G Sptssa serine palmitoyltransferase small subunit A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431) MGI
TreeGrafter		 PMID:25691431 GO_REF:0000118 NCBI chrNW_004624838:2,207,003...2,231,838
Ensembl chrNW_004624838:2,206,917...2,231,518 		JBrowse link
G Sptssb serine palmitoyltransferase small subunit B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:26438849) Ensembl
MGI
TreeGrafter		 PMID:26438849 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624730:39,280,846...39,324,174
Ensembl chrNW_004624730:39,291,652...39,323,139 		JBrowse link
G Tlcd3b TLC domain containing 3B acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:23275342) MGI
Ensembl
TreeGrafter		 PMID:23275342 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624782:13,203,954...13,212,174
Ensembl chrNW_004624782:13,203,963...13,213,797 		JBrowse link
ceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer1 alkaline ceramidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12783875) TreeGrafter
MGI		 PMID:12783875 GO_REF:0000118 NCBI chrNW_004624828:4,022,288...4,046,235
Ensembl chrNW_004624828:4,041,875...4,045,675 		JBrowse link
G Acer2 alkaline ceramidase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624736:23,363,806...23,556,247
Ensembl chrNW_004624736:23,363,983...23,411,100 		JBrowse link
G Acer3 alkaline ceramidase 3 involved_in ISO (MGI:5749603|PMID:26474409)
(PMID:30575723)
(PMID:20207939), (PMID:26792856)		 UniProt PMID:20207939 PMID:26474409 PMID:26792856 PMID:30575723 MGI:5749603 NCBI chrNW_004624863:37,148...96,550
Ensembl chrNW_004624863:37,148...95,211 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 involved_in ISO (MGI:5505361|PMID:23770692)
(PMID:12815059)
(PMID:10610716)
(MGI:1267186|PMID:9653654)		 UniProt PMID:9653654 PMID:10610716 PMID:12815059 PMID:23770692 MGI:1267186 MGI:5505361 NCBI chrNW_004624769:21,112,705...21,140,004
Ensembl chrNW_004624769:21,112,851...21,138,831 		JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624791:12,906,908...13,059,033
Ensembl chrNW_004624791:12,907,485...13,059,005 		JBrowse link
G LOC101696378 bile salt-activated lipase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624760:3,380,687...3,402,138
Ensembl chrNW_004624760:3,380,769...3,398,391 		JBrowse link
galactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3galt1 beta-1,3-galactosyltransferase 1 involved_in ISO (PMID:9582303) BHF-UCL PMID:9582303 NCBI chrNW_004624787:5,040,161...5,582,911
Ensembl chrNW_004624787:5,578,168...5,579,148 		JBrowse link
G B3galt2 beta-1,3-galactosyltransferase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624814:375,039...382,732
Ensembl chrNW_004624814:375,040...381,702 		JBrowse link
G B4galt3 beta-1,4-galactosyltransferase 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624794:205,726...212,141
Ensembl chrNW_004624794:206,591...212,141 		JBrowse link
G Fa2h fatty acid 2-hydroxylase involved_in ISO (MGI:3696647|PMID:15658937)
(MGI:3826747|PMID:18815260)
PMID:17901466		 UniProt PMID:15658937 PMID:17901466 PMID:18815260 MGI:3696647 MGI:3826747 RGD:13825191 NCBI chrNW_004624746:12,125,709...12,186,254
Ensembl chrNW_004624746:12,125,506...12,186,671 		JBrowse link
G Gal3st1 galactose-3-O-sulfotransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10727929) TreeGrafter
MGI		 PMID:10727929 GO_REF:0000118 NCBI chrNW_004625705:1,409...4,810
Ensembl chrNW_004625705:2,469...4,916 		JBrowse link
G Ugt8 UDP glycosyltransferase 8 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624867:1,182,674...1,255,714
Ensembl chrNW_004624867:1,182,589...1,255,796 		JBrowse link
galactosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Galc galactosylceramidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11371512) TreeGrafter
MGI
InterPro		 PMID:11371512 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624734:14,355,349...14,462,869
Ensembl chrNW_004624734:14,355,435...14,407,087 		JBrowse link
G Psap prosaposin acts_upstream_of_or_within ISO (PMID:11371512) MGI PMID:11371512 NCBI chrNW_004624754:5,725,697...5,753,575
Ensembl chrNW_004624754:5,726,681...5,753,575 		JBrowse link
galactosylceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gal3st1 galactose-3-O-sulfotransferase 1 involved_in ISO (MGI:6436415|PMID:9030544) UniProt PMID:9030544 MGI:6436415 NCBI chrNW_004625705:1,409...4,810
Ensembl chrNW_004625705:2,469...4,916 		JBrowse link
ganglioside biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3galt4 beta-1,3-galactosyltransferase 4 involved_in ISO (PMID:9582303) BHF-UCL PMID:9582303 NCBI chrNW_004624754:23,542,500...23,543,855 JBrowse link
G B4galnt1 beta-1,4-N-acetyl-galactosaminyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10021458) TreeGrafter
MGI
Ensembl		 PMID:10021458 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624802:10,329,295...10,337,205
Ensembl chrNW_004624802:10,329,296...10,337,283 		JBrowse link
G St6galnac3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624742:20,405,342...20,928,792
Ensembl chrNW_004624742:20,407,410...20,928,766 		JBrowse link
G St6galnac4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624760:7,652,907...7,660,858
Ensembl chrNW_004624760:7,652,881...7,662,382 		JBrowse link
G St6galnac6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:10702226) MGI
TreeGrafter		 PMID:10702226 GO_REF:0000118 NCBI chrNW_004624760:7,666,798...7,678,926
Ensembl chrNW_004624760:7,667,189...7,677,662 		JBrowse link
G St8sia2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624768:11,238,134...11,302,280
Ensembl chrNW_004624768:11,234,281...11,302,237 		JBrowse link
G St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 involved_in ISO (PMID:10766765)
(MGI:74245|PMID:7782326)		 BHF-UCL
UniProt		 PMID:7782326 PMID:10766765 MGI:74245 NCBI chrNW_004624792:2,881,545...2,897,891
Ensembl chrNW_004624792:2,881,068...2,888,943 		JBrowse link
G St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624743:19,225,065...19,313,177
Ensembl chrNW_004624743:19,228,696...19,313,243 		JBrowse link
G St8sia6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 involved_in ISO (MGI:2182536|PMID:11980897) BHF-UCL PMID:11980897 MGI:2182536 NCBI chrNW_004624796:10,383,947...10,577,117
Ensembl chrNW_004624796:10,458,466...10,570,959 		JBrowse link
ganglioside biosynthetic process via lactosylceramide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galt5 beta-1,4-galactosyltransferase 5 involved_in ISO (MGI:6196231|PMID:30114188) UniProt PMID:30114188 MGI:6196231 NCBI chrNW_004624790:5,770,586...5,792,036
Ensembl chrNW_004624790:5,766,903...5,789,140 		JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 involved_in ISO (MGI:6196231|PMID:30114188) UniProt PMID:30114188 MGI:6196231 NCBI chrNW_004624770:1,119,202...1,239,127
Ensembl chrNW_004624770:1,160,120...1,240,016 		JBrowse link
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 involved_in IEA TreeGrafter
UniProt
Ensembl		 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chrNW_004624735:22,510,500...22,589,666
Ensembl chrNW_004624735:22,528,976...22,589,666 		JBrowse link
G St3gal2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 involved_in IEA TreeGrafter
UniProt		 GO_REF:0000117 GO_REF:0000118 NCBI chrNW_004624746:12,623,966...12,680,430
Ensembl chrNW_004624746:12,623,730...12,680,436 		JBrowse link
G St3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 involved_in ISO (MGI:6467685|PMID:22735313) UniProt PMID:22735313 MGI:6467685 NCBI chrNW_004624892:2,984,329...3,213,017
Ensembl chrNW_004624892:2,984,351...3,213,021 		JBrowse link
ganglioside catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gm2a GM2 ganglioside activator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9223328) TreeGrafter
MGI
InterPro		 PMID:9223328 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624733:41,141,507...41,152,957
Ensembl chrNW_004624733:41,141,552...41,156,188 		JBrowse link
G Hexa hexosaminidase subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7937929), (PMID:9223328)
(PMID:8789434), (PMID:9645704)		 TreeGrafter
MGI		 PMID:7937929 PMID:8789434 PMID:9223328 PMID:9645704 GO_REF:0000118 NCBI chrNW_004624781:1,686,818...1,706,044
Ensembl chrNW_004624781:1,686,384...1,714,684 		JBrowse link
G Hexb hexosaminidase subunit beta acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:8789434), (PMID:9645704)
(PMID:10021458), (PMID:12657883), (PMID:12756243), (PMID:15748167), (PMID:9223328)
(PMID:8566348)		 MGI
Ensembl
TreeGrafter		 PMID:8566348 PMID:8789434 PMID:9223328 PMID:9645704 PMID:10021458 More... GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624924:195,406...219,232
Ensembl chrNW_004624924:195,175...219,278 		JBrowse link
G Neu1 neuraminidase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624754:24,382,509...24,386,410
Ensembl chrNW_004624754:24,382,467...24,387,874 		JBrowse link
G Neu2 neuraminidase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624843:5,666,959...5,671,833
Ensembl chrNW_004624843:5,665,448...5,670,832 		JBrowse link
G Neu3 neuraminidase 3 involved_in ISO (MGI:3040535|PMID:14970224), (MGI:3765376|PMID:17708748), (MGI:6478528|PMID:11696012)
(PMID:10861246), (PMID:11298736), (PMID:15847605), (PMID:17334392)		 UniProt PMID:10861246 PMID:11298736 PMID:11696012 PMID:14970224 PMID:15847605 More... MGI:3040535 MGI:3765376 MGI:6478528 NCBI chrNW_004624817:2,107,893...2,133,626 JBrowse link
G Neu4 neuraminidase 4 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624847:5,716,165...5,720,542
Ensembl chrNW_004624847:5,716,659...5,720,542 		JBrowse link
ganglioside metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 involved_in ISO (MGI:3718765|PMID:17488728) UniProt PMID:17488728 MGI:3718765 NCBI chrNW_004624760:880,216...898,753
Ensembl chrNW_004624760:880,148...898,751 		JBrowse link
G Cln6 CLN6 transmembrane ER protein involved_in ISO (PMID:16857350) UniProt PMID:16857350 NCBI chrNW_004624781:4,866,896...4,879,321
Ensembl chrNW_004624781:4,866,927...4,879,321 		JBrowse link
G Gm2a GM2 ganglioside activator ISO RGD PMID:9770472 RGD:1598995 NCBI chrNW_004624733:41,141,507...41,152,957
Ensembl chrNW_004624733:41,141,552...41,156,188 		JBrowse link
G Itgb8 integrin subunit beta 8 acts_upstream_of_or_within ISO (PMID:16251442) MGI PMID:16251442 NCBI chrNW_004624739:10,164,645...10,261,732
Ensembl chrNW_004624739:10,168,495...10,259,804 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO (PMID:21408219) MGI PMID:21408219 NCBI chrNW_004624795:1,553,582...1,558,110
Ensembl chrNW_004624795:1,553,037...1,558,197 		JBrowse link
glucosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fa2h fatty acid 2-hydroxylase involved_in ISO (MGI:5285470|PMID:21628453) UniProt PMID:21628453 MGI:5285470 NCBI chrNW_004624746:12,125,709...12,186,254
Ensembl chrNW_004624746:12,125,506...12,186,671 		JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624760:23,059,141...23,094,013
Ensembl chrNW_004624760:23,056,929...23,094,010 		JBrowse link
glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba1 glucosylceramidase beta 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624885:2,315,371...2,321,327
Ensembl chrNW_004624885:2,315,142...2,321,327 		JBrowse link
G Gba2 glucosylceramidase beta 2 involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004624868:5,045,566...5,056,419
Ensembl chrNW_004624868:5,045,594...5,056,416 		JBrowse link
glucosylceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba1 glucosylceramidase beta 1 acts_upstream_of_or_within ISO (PMID:17954912), (PMID:18346921) MGI PMID:17954912 PMID:18346921 NCBI chrNW_004624885:2,315,371...2,321,327
Ensembl chrNW_004624885:2,315,142...2,321,327 		JBrowse link
G Psap prosaposin acts_upstream_of_or_within ISO (PMID:17353235) MGI PMID:17353235 NCBI chrNW_004624754:5,725,697...5,753,575
Ensembl chrNW_004624754:5,726,681...5,753,575 		JBrowse link
glycosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gla galactosidase alpha acts_upstream_of_or_within ISO (PMID:10840053), (PMID:15629890)
(PMID:10841515), (PMID:11752062), (PMID:9122231)		 MGI PMID:9122231 PMID:10840053 PMID:10841515 PMID:11752062 PMID:15629890 NCBI chrNW_004624902:1,163,360...1,173,087
Ensembl chrNW_004624902:1,163,611...1,173,177 		JBrowse link
G Lct lactase involved_in ISO PMID:4752949 UniProt PMID:4752949 RGD:151356630 NCBI chrNW_004624732:35,125,995...35,177,055
Ensembl chrNW_004624732:35,125,287...35,175,062 		JBrowse link
glycosylceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G St6galnac3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 involved_in ISO (PMID:17123352) BHF-UCL PMID:17123352 NCBI chrNW_004624742:20,405,342...20,928,792
Ensembl chrNW_004624742:20,407,410...20,928,766 		JBrowse link
G St6galnac6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 involved_in ISO (PMID:17123352) BHF-UCL PMID:17123352 NCBI chrNW_004624760:7,666,798...7,678,926
Ensembl chrNW_004624760:7,667,189...7,677,662 		JBrowse link
lactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galt4 beta-1,4-galactosyltransferase 4 involved_in ISO (PMID:9792633) UniProt PMID:9792633 NCBI chrNW_004624731:28,929,599...28,972,417
Ensembl chrNW_004624731:28,939,838...28,971,652 		JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 involved_in ISO (PMID:10320813) BHF-UCL PMID:10320813 NCBI chrNW_004624770:1,119,202...1,239,127
Ensembl chrNW_004624770:1,160,120...1,240,016 		JBrowse link
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 acts_upstream_of_or_within ISO (PMID:25691431) MGI PMID:25691431 NCBI chrNW_004624802:12,197,114...12,200,044
Ensembl chrNW_004624802:12,197,114...12,199,983 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of_or_within ISO (PMID:25691431) MGI PMID:25691431 NCBI chrNW_004624795:3,210,382...3,216,130
Ensembl chrNW_004624795:3,209,605...3,217,539 		JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISO (MGI:6294167|PMID:16118219)
(PMID:16118219)		 UniProt PMID:16118219 MGI:6294167 NCBI chrNW_004624801:6,253,219...6,257,128 JBrowse link
omega-hydroxyceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnpla1 patatin like phospholipase domain containing 1 involved_in ISO (MGI:5888934|PMID:28248300)
(PMID:28248318)		 UniProt PMID:28248300 PMID:28248318 MGI:5888934 NCBI chrNW_004624754:21,370,872...21,410,804
Ensembl chrNW_004624754:21,375,463...21,410,961 		JBrowse link
positive regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn1 cellular communication network factor 1 acts_upstream_of_or_within ISO (PMID:19364818) MGI PMID:19364818 NCBI chrNW_004624742:11,882,815...11,885,686
Ensembl chrNW_004624742:11,882,907...11,885,667 		JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISO (MGI:4947032|PMID:21177474) UniProt PMID:21177474 MGI:4947032 NCBI chrNW_004624801:8,895,138...8,901,848
Ensembl chrNW_004624801:8,895,836...8,903,952 		JBrowse link
G Pla2g6 phospholipase A2 group VI involved_in IEA
ISO		 TreeGrafter
RGD		 PMID:18936091 GO_REF:0000118 RGD:6482750 NCBI chrNW_004624752:9,792,778...9,841,817
Ensembl chrNW_004624752:9,792,807...9,843,457 		JBrowse link
G Prkcd protein kinase C delta involved_in ISO (PMID:19279011) BHF-UCL PMID:19279011 NCBI chrNW_004624822:4,035,819...4,062,907
Ensembl chrNW_004624822:4,033,130...4,059,555 		JBrowse link
G Sirt3 sirtuin 3 involved_in ISO (MGI:5755322|PMID:26620563) UniProt PMID:26620563 MGI:5755322 NCBI chrNW_004624766:22,199,741...22,233,933
Ensembl chrNW_004624766:22,199,601...22,233,933 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 ISO RGD PMID:20096352 RGD:10041064 NCBI chrNW_004624746:17,857,779...17,948,469
Ensembl chrNW_004624746:17,920,835...17,948,468 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO (PMID:16118219)
(MGI:6294167|PMID:16118219)		 UniProt PMID:16118219 MGI:6294167 NCBI chrNW_004624832:5,246,328...5,254,247
Ensembl chrNW_004624832:5,246,895...5,253,207 		JBrowse link
G Znf750 zinc finger protein 750 acts_upstream_of_or_within ISO (PMID:37115925) MGI PMID:37115925 NCBI chrNW_004624801:11,519,383...11,528,264
Ensembl chrNW_004624801:11,520,636...11,522,890 		JBrowse link
positive regulation of glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkcd protein kinase C delta involved_in ISO (PMID:19279011) BHF-UCL PMID:19279011 NCBI chrNW_004624822:4,035,819...4,062,907
Ensembl chrNW_004624822:4,033,130...4,059,555 		JBrowse link
regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101706228 ORM1-like protein 1 involved_in IEA UniProt GO_REF:0000104 GO_REF:0000117 NCBI chrNW_004624753:15,730,590...15,731,228 JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 involved_in IEA UniProt GO_REF:0000104 GO_REF:0000117 NCBI chrNW_004624802:12,197,114...12,200,044
Ensembl chrNW_004624802:12,197,114...12,199,983 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:31880535) UniProt
MGI		 PMID:31880535 GO_REF:0000104 GO_REF:0000117 NCBI chrNW_004624795:3,210,382...3,216,130
Ensembl chrNW_004624795:3,209,605...3,217,539 		JBrowse link
G Paqr4 progestin and adipoQ receptor family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624824:711,755...715,815
Ensembl chrNW_004624824:712,355...715,700 		JBrowse link
G Prkcd protein kinase C delta involved_in ISO (PMID:17303575) UniProt PMID:17303575 NCBI chrNW_004624822:4,035,819...4,062,907
Ensembl chrNW_004624822:4,033,130...4,059,555 		JBrowse link
G Samd8 sterile alpha motif domain containing 8 involved_in ISO (PMID:19506037) UniProt PMID:19506037 NCBI chrNW_004624754:8,466,049...8,553,721
Ensembl chrNW_004624754:8,465,981...8,550,666 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15225
    metabolic process 9678
      amide metabolic process 394
        ceramide metabolic process 100
          ceramide biosynthetic process + 67
          ceramide catabolic process + 20
          ganglioside metabolic process + 25
          glycosylceramide metabolic process + 16
          lactosylceramide metabolic process + 2
Path 2
Term Annotations click to browse term
  biological_process 15225
    metabolic process 9678
      primary metabolic process 8614
        lipid metabolic process 1186
          cellular lipid metabolic process 878
            membrane lipid metabolic process 189
              sphingolipid metabolic process 141
                ceramide metabolic process 100
                  ceramide biosynthetic process + 67
                  ceramide catabolic process + 20
                  ganglioside metabolic process + 25
                  glycosylceramide metabolic process + 16
                  lactosylceramide metabolic process + 2
paths to the root