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ONTOLOGY REPORT - ANNOTATIONS

Term:ceramide metabolic process
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Accession:GO:0006672 term browser browse the term
Definition:The chemical reactions and pathways involving ceramides, any N-acylated sphingoid.
Synonyms:exact_synonym: ceramide metabolism


show annotations for term's descendants           Sort by:
ceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA12 ATP binding cassette subfamily A member 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:22,136,732...22,306,917
Ensembl chr37:22,138,245...22,405,736 		JBrowse link
G ACER1 alkaline ceramidase 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr20:53,819,224...53,838,183
Ensembl chr20:53,819,074...53,838,438 		JBrowse link
G ACER2 alkaline ceramidase 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr11:39,190,873...39,223,590
Ensembl chr11:39,190,115...39,219,776 		JBrowse link
G ACER3 alkaline ceramidase 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr21:21,711,315...21,863,409
Ensembl chr21:21,714,156...21,863,320 		JBrowse link
G ASAH2 N-acylsphingosine amidohydrolase 2 involved_in IEA UniProt GO_REF:0000117 NCBI chr26:37,136,601...37,228,215
Ensembl chr26:37,136,897...37,218,783 		JBrowse link
G CERK ceramide kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:19,560,125...19,601,223
Ensembl chr10:19,556,087...19,598,954 		JBrowse link
G CERT1 ceramide transporter 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19139267) Ensembl
MGI		 PMID:19139267 GO_REF:0000107 NCBI chr 3:30,860,103...30,964,991
Ensembl chr 3:30,859,569...30,962,337 		JBrowse link
G CLN8 CLN8 transmembrane ER and ERGIC protein involved_in ISS UniProt GO_REF:0000024 NCBI chr37:30,863,098...30,885,831
Ensembl chr37:30,867,479...30,884,895 		JBrowse link
G FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase) involved_in ISO (PMID:17604274) BHF-UCL PMID:17604274 NCBI chr20:54,216,560...54,238,103
Ensembl chr20:54,224,789...54,225,841 		JBrowse link
G FUT7 fucosyltransferase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:48,604,879...48,609,292
Ensembl chr 9:48,606,435...48,609,303 		JBrowse link
G HTRA2 HtrA serine peptidase 2 ISO C2 ceramide RGD PMID:22296759 RGD:5688365 NCBI chr17:48,610,408...48,613,399
Ensembl chr17:48,610,408...48,613,399 		JBrowse link
G ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 involved_in IEA Ensembl
UniProt		 GO_REF:0000104 GO_REF:0000107 NCBI chr37:509,592...521,511
Ensembl chr37:511,149...522,865 		JBrowse link
G ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 involved_in IEA UniProt GO_REF:0000104 NCBI chr10:203,750...206,247 JBrowse link
G ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 involved_in IEA Ensembl
UniProt		 GO_REF:0000104 GO_REF:0000107 NCBI chr 9:22,594,425...22,601,108
Ensembl chr 9:22,594,480...22,599,999 		JBrowse link
G PLA2G15 phospholipase A2 group XV involved_in
acts_upstream_of_or_within		 ISS
ISO
IBA
IEA		 (PMID:11790796) UniProt
MGI
GO_Central
Ensembl		 PMID:11790796 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:81,269,914...81,280,700
Ensembl chr 5:81,269,920...81,280,700 		JBrowse link
G PLPP1 phospholipid phosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:42,761,712...42,854,515
Ensembl chr 2:42,763,026...42,854,802 		JBrowse link
G PLPP2 phospholipid phosphatase 2 involved_in ISO (PMID:9705349) UniProt PMID:9705349 NCBI chr20:58,083,902...58,095,621
Ensembl chr20:58,087,289...58,095,421 		JBrowse link
G PLPP3 phospholipid phosphatase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:52,924,443...53,006,298
Ensembl chr 5:52,923,833...53,005,493 		JBrowse link
G PSAP prosaposin acts_upstream_of_or_within ISO (PMID:17353235)
(PMID:15345707)		 MGI PMID:15345707 PMID:17353235 NCBI chr 4:22,571,095...22,603,880
Ensembl chr 4:22,572,153...22,603,848 		JBrowse link
G SGPL1 sphingosine-1-phosphate lyase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:21,666,264...21,717,476
Ensembl chr 4:21,660,939...21,715,155 		JBrowse link
G SMPD1 sphingomyelin phosphodiesterase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23046545) Ensembl
MGI		 PMID:23046545 GO_REF:0000107 NCBI chr21:29,714,418...29,719,035
Ensembl chr21:29,714,557...29,719,033 		JBrowse link
G SMPD2 sphingomyelin phosphodiesterase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:66,347,628...66,350,322
Ensembl chr12:66,323,022...66,350,322 		JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22383528), (PMID:23046545) Ensembl
MGI		 PMID:22383528 PMID:23046545 GO_REF:0000107 NCBI chr 5:81,089,657...81,172,173
Ensembl chr 5:81,142,888...81,172,189 		JBrowse link
G SMPD5 sphingomyelin phosphodiesterase 5 involved_in IEA Ensembl GO_REF:0000107
G TM9SF2 transmembrane 9 superfamily member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:49,515,350...49,578,519
Ensembl chr22:49,515,382...49,577,905 		JBrowse link
ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGK acylglycerol kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15252046) Ensembl
MGI		 PMID:15252046 GO_REF:0000107 NCBI chr16:7,561,084...7,637,017
Ensembl chr16:7,561,305...7,637,015 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:32,899,416...32,911,442
Ensembl chr 5:32,896,238...32,911,552 		JBrowse link
G ALOXE3 arachidonate lipoxygenase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22832496) Ensembl
MGI		 PMID:22832496 GO_REF:0000107 NCBI chr 5:32,917,681...32,941,470
Ensembl chr 5:32,918,065...32,941,752 		JBrowse link
G ASAH1 N-acylsphingosine amidohydrolase 1 involved_in ISO (PMID:12764132), (PMID:12815059) UniProt PMID:12764132 PMID:12815059 NCBI chr16:41,297,215...41,335,521
Ensembl chr16:41,297,809...41,323,078 		JBrowse link
G ASAH2 N-acylsphingosine amidohydrolase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:37,136,601...37,228,215
Ensembl chr26:37,136,897...37,218,783 		JBrowse link
G CERS1 ceramide synthase 1 involved_in IEA Ensembl
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 NCBI chr20:44,216,568...44,231,820 JBrowse link
G CERS2 ceramide synthase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15823095) InterPro
MGI
Ensembl
UniProt		 PMID:15823095 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 NCBI chr17:60,069,723...60,073,622
Ensembl chr17:60,070,585...60,081,502 		JBrowse link
G CERS3 ceramide synthase 3 involved_in IEA InterPro
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 NCBI chr 3:40,448,174...40,570,736
Ensembl chr 3:40,459,162...40,568,272 		JBrowse link
G CERS4 ceramide synthase 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12912983), (PMID:15823095) InterPro
MGI
Ensembl
UniProt		 PMID:12912983 PMID:15823095 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 NCBI chr20:52,829,482...52,860,783
Ensembl chr20:52,829,316...52,860,803 		JBrowse link
G CERS5 ceramide synthase 5 involved_in IEA InterPro
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 NCBI chr27:4,565,940...4,597,036
Ensembl chr27:4,565,420...4,602,391 		JBrowse link
G CERS6 ceramide synthase 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15823095) InterPro
MGI
UniProt		 PMID:15823095 GO_REF:0000002 GO_REF:0000117 NCBI chr36:13,307,461...13,608,123
Ensembl chr36:13,308,110...13,602,875 		JBrowse link
G CYP4F22 cytochrome P450 family 4 subfamily F member 22 involved_in ISO (PMID:26056268) UniProt PMID:26056268 NCBI chr20:46,674,580...46,743,183
Ensembl chr20:46,458,620...46,705,789 		JBrowse link
G DEGS1 delta 4-desaturase, sphingolipid 1 acts_upstream_of_or_within ISO (PMID:22984457) MGI PMID:22984457 NCBI chr 7:40,147,293...40,152,190
Ensembl chr 7:40,147,505...40,153,085 		JBrowse link
G ELOVL1 ELOVL fatty acid elongase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:16,798,305...16,803,071
Ensembl chr15:16,798,370...16,802,899 		JBrowse link
G FA2H fatty acid 2-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:75,878,539...75,923,886
Ensembl chr 5:75,878,243...75,948,094 		JBrowse link
G GBA1 glucosylceramidase beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:42,317,704...42,322,285
Ensembl chr 7:42,317,862...42,322,864 		JBrowse link
G MECR mitochondrial trans-2-enoyl-CoA reductase acts_upstream_of
involved_in		 ISO
IEA		 (PMID:37653044) UniProt
Ensembl		 PMID:37653044 GO_REF:0000107 NCBI chr 2:71,369,768...71,400,499
Ensembl chr 2:71,369,806...71,400,499 		JBrowse link
G P2RX1 purinergic receptor P2X 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16325464) Ensembl
MGI		 PMID:16325464 GO_REF:0000107 NCBI chr 9:47,674,175...47,694,358
Ensembl chr 9:47,675,300...47,688,858 		JBrowse link
G P2RX7 purinergic receptor P2X 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16325464) Ensembl
MGI		 PMID:16325464 GO_REF:0000107 NCBI chr26:7,928,863...7,983,956
Ensembl chr26:7,940,985...7,983,740 		JBrowse link
G PNPLA1 patatin like phospholipase domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:5,377,430...5,423,556
Ensembl chr12:5,377,430...5,423,556 		JBrowse link
G SAMD8 sterile alpha motif domain containing 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25605874), (PMID:25667419)
(PMID:25667419)		 Ensembl
MGI		 PMID:25605874 PMID:25667419 GO_REF:0000107 NCBI chr 4:25,375,127...25,424,792
Ensembl chr 4:25,374,837...25,421,075 		JBrowse link
G SGMS1 sphingomyelin synthase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25605874) MGI
Ensembl		 PMID:25605874 GO_REF:0000107 NCBI chr26:37,243,388...37,472,806
Ensembl chr26:37,244,900...37,348,802 		JBrowse link
G SGMS2 sphingomyelin synthase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25605874) Ensembl
MGI		 PMID:25605874 GO_REF:0000107 NCBI chr32:28,277,195...28,407,761
Ensembl chr32:28,354,116...28,403,734 		JBrowse link
G SMPD1 sphingomyelin phosphodiesterase 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:17261082 GO_REF:0000107 RGD:1601344 NCBI chr21:29,714,418...29,719,035
Ensembl chr21:29,714,557...29,719,033 		JBrowse link
G SMPD2 sphingomyelin phosphodiesterase 2 ISO RGD PMID:12473648 RGD:1581395 NCBI chr12:66,347,628...66,350,322
Ensembl chr12:66,323,022...66,350,322 		JBrowse link
G SMPD4 sphingomyelin phosphodiesterase 4 involved_in ISO (PMID:16517606), (PMID:25180167)
(MGI:6450503|PMID:25180167)		 BHF-UCL
UniProt		 PMID:16517606 PMID:25180167 MGI:6450503 NCBI chr26:30,397,687...30,419,072
Ensembl chr26:30,398,768...30,418,979 		JBrowse link
G SMPD5 sphingomyelin phosphodiesterase 5 involved_in IEA Ensembl GO_REF:0000107
G SPTLC1 serine palmitoyltransferase long chain base subunit 1 acts_upstream_of_or_within ISO (PMID:25691431)
(PMID:16216550)		 MGI PMID:16216550 PMID:25691431 NCBI chr 1:94,997,240...95,062,424
Ensembl chr 1:94,997,290...95,064,468 		JBrowse link
G SPTLC2 serine palmitoyltransferase long chain base subunit 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431)
(PMID:16216550)		 MGI
Ensembl		 PMID:16216550 PMID:25691431 GO_REF:0000107 NCBI chr 8:50,291,797...50,401,202
Ensembl chr 8:50,271,010...50,401,313 		JBrowse link
G SPTSSA serine palmitoyltransferase small subunit A acts_upstream_of_or_within ISO (PMID:25691431) MGI PMID:25691431
G SPTSSB serine palmitoyltransferase small subunit B acts_upstream_of_or_within ISO (PMID:26438849) MGI PMID:26438849 NCBI chr34:27,321,108...27,350,436
Ensembl chr34:27,322,405...27,322,635 		JBrowse link
G TLCD3B TLC domain containing 3B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23275342) Ensembl
MGI		 PMID:23275342 GO_REF:0000107 NCBI chr 6:18,053,841...18,062,755
Ensembl chr 6:18,054,632...18,055,914 		JBrowse link
ceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACER1 alkaline ceramidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12783875) Ensembl
MGI		 PMID:12783875 GO_REF:0000107 NCBI chr20:53,819,224...53,838,183
Ensembl chr20:53,819,074...53,838,438 		JBrowse link
G ACER2 alkaline ceramidase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:39,190,873...39,223,590
Ensembl chr11:39,190,115...39,219,776 		JBrowse link
G ACER3 alkaline ceramidase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:21,711,315...21,863,409
Ensembl chr21:21,714,156...21,863,320 		JBrowse link
G ASAH1 N-acylsphingosine amidohydrolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:41,297,215...41,335,521
Ensembl chr16:41,297,809...41,323,078 		JBrowse link
G ASAH2 N-acylsphingosine amidohydrolase 2 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr26:37,136,601...37,228,215
Ensembl chr26:37,136,897...37,218,783 		JBrowse link
G CEL carboxyl ester lipase acts_upstream_of_or_within ISO (PMID:11733511) MGI PMID:11733511 NCBI chr 9:51,337,205...51,345,284
Ensembl chr 9:51,337,187...51,362,422 		JBrowse link
galactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3GALT1 beta-1,3-galactosyltransferase 1 involved_in ISO (PMID:9582303) BHF-UCL PMID:9582303 NCBI chr36:12,263,162...12,766,525
Ensembl chr36:12,761,821...12,762,801 		JBrowse link
G B3GALT2 beta-1,3-galactosyltransferase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:5,868,822...5,876,539
Ensembl chr38:5,874,011...5,875,279 		JBrowse link
G B4GALT3 beta-1,4-galactosyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:21,301,835...21,306,854
Ensembl chr38:21,302,003...21,312,958 		JBrowse link
G FA2H fatty acid 2-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:75,878,539...75,923,886
Ensembl chr 5:75,878,243...75,948,094 		JBrowse link
G GAL3ST1 galactose-3-O-sulfotransferase 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 (PMID:10727929) GO_Central
MGI		 PMID:10727929 GO_REF:0000033 NCBI chr26:23,634,884...23,654,205
Ensembl chr26:23,637,844...23,646,219 		JBrowse link
G UGT8 UDP glycosyltransferase 8 involved_in ISO PMID:8713090 UniProt PMID:8713090 RGD:39458006 NCBI chr32:34,148,874...34,250,891
Ensembl chr32:34,179,247...34,233,116 		JBrowse link
galactosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GALC galactosylceramidase involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
ISS		 (PMID:11371512) InterPro
MGI
GO_Central
Ensembl
UniProt		 PMID:11371512 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:59,266,693...59,324,825
Ensembl chr 8:59,267,818...59,324,967 		JBrowse link
G GBA3 glucosylceramidase beta 3 involved_in ISO (PMID:17595169) UniProt PMID:17595169 NCBI chr 3:87,080,351...87,190,931
Ensembl chr 3:87,081,134...87,190,987 		JBrowse link
G PSAP prosaposin acts_upstream_of_or_within ISO (PMID:11371512) MGI PMID:11371512 NCBI chr 4:22,571,095...22,603,880
Ensembl chr 4:22,572,153...22,603,848 		JBrowse link
galactosylceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GAL3ST1 galactose-3-O-sulfotransferase 1 involved_in ISO (MGI:6436415|PMID:9030544) UniProt PMID:9030544 MGI:6436415 NCBI chr26:23,634,884...23,654,205
Ensembl chr26:23,637,844...23,646,219 		JBrowse link
ganglioside biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3GALT4 beta-1,3-galactosyltransferase 4 involved_in ISO (PMID:9582303) BHF-UCL PMID:9582303 NCBI chr12:2,719,112...2,720,997 JBrowse link
G B4GALNT1 beta-1,4-N-acetyl-galactosaminyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10021458) Ensembl
MGI		 PMID:10021458 GO_REF:0000107 NCBI chr10:1,703,846...1,756,837
Ensembl chr10:1,703,169...1,709,994 		JBrowse link
G ST6GALNAC6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10702226) Ensembl
MGI		 PMID:10702226 GO_REF:0000107 NCBI chr 9:55,520,083...55,533,205
Ensembl chr 9:55,520,109...55,532,055 		JBrowse link
G ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:47,588,804...47,654,853
Ensembl chr 3:47,588,797...47,655,593 		JBrowse link
G ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:18,541,197...18,557,887
Ensembl chr 1:18,549,942...18,557,893 		JBrowse link
G ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:9,708,130...9,801,547
Ensembl chr 3:9,708,173...9,845,015 		JBrowse link
G ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:19,392,690...19,618,127
Ensembl chr 2:19,482,468...19,616,339 		JBrowse link
ganglioside biosynthetic process via lactosylceramide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4GALT5 beta-1,4-galactosyltransferase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:36,220,973...36,241,482
Ensembl chr24:36,221,189...36,300,804 		JBrowse link
G B4GALT6 beta-1,4-galactosyltransferase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:57,849,872...57,917,289
Ensembl chr 7:57,849,884...57,914,360 		JBrowse link
G ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:29,853,182...29,949,004
Ensembl chr13:29,846,834...29,872,918 		JBrowse link
G ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:76,377,782...76,427,998
Ensembl chr 5:76,379,702...76,394,525 		JBrowse link
G ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:16,324,752...16,434,256
Ensembl chr15:16,324,899...16,401,616 		JBrowse link
ganglioside catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GM2A ganglioside GM2 activator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9223328) Ensembl
MGI
InterPro		 PMID:9223328 GO_REF:0000002 GO_REF:0000107 NCBI chr 4:58,002,438...58,016,003
Ensembl chr 4:58,003,946...58,015,753 		JBrowse link
G HEXA hexosaminidase subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7937929), (PMID:9223328)
(PMID:8789434), (PMID:9645704)		 Ensembl
MGI		 PMID:7937929 PMID:8789434 PMID:9223328 PMID:9645704 GO_REF:0000107 NCBI chr30:35,836,788...35,862,525 JBrowse link
G HEXB hexosaminidase subunit beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8566348)
(PMID:10021458), (PMID:12657883), (PMID:12756243), (PMID:15748167), (PMID:9223328)
(PMID:8789434), (PMID:9645704)		 Ensembl
MGI		 PMID:8566348 PMID:8789434 PMID:9223328 PMID:9645704 PMID:10021458 More... GO_REF:0000107 NCBI chr 2:57,221,809...57,248,432
Ensembl chr 2:57,222,186...57,248,417 		JBrowse link
G NEU2 neuraminidase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:44,563,664...44,596,837
Ensembl chr25:44,563,411...44,595,653 		JBrowse link
G NEU3 neuraminidase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:23,456,424...23,484,872 JBrowse link
G NEU4 neuraminidase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:51,594,865...51,602,500 JBrowse link
ganglioside metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 involved_in ISO (MGI:3718765|PMID:17488728) UniProt PMID:17488728 MGI:3718765 NCBI chr 9:48,610,906...48,630,932
Ensembl chr 9:48,613,996...48,629,857 		JBrowse link
G CLN6 CLN6 transmembrane ER protein involved_in ISS UniProt GO_REF:0000024 NCBI chr30:32,246,394...32,264,251
Ensembl chr30:32,246,411...32,264,240 		JBrowse link
G GM2A ganglioside GM2 activator ISO RGD PMID:9770472 RGD:1598995 NCBI chr 4:58,002,438...58,016,003
Ensembl chr 4:58,003,946...58,015,753 		JBrowse link
G ITGB8 integrin subunit beta 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16251442) Ensembl
MGI		 PMID:16251442 GO_REF:0000107 NCBI chr14:34,370,957...34,449,091
Ensembl chr14:34,349,232...34,444,235 		JBrowse link
G NAGLU N-acetyl-alpha-glucosaminidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21408219) Ensembl
MGI		 PMID:21408219 GO_REF:0000107 NCBI chr 9:20,407,296...20,414,094
Ensembl chr 9:20,407,281...20,414,056 		JBrowse link
glucosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FA2H fatty acid 2-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:75,878,539...75,923,886
Ensembl chr 5:75,878,243...75,948,094 		JBrowse link
G UGCG UDP-glucose ceramide glucosyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:66,439,346...66,472,897
Ensembl chr11:66,439,346...66,472,897 		JBrowse link
glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GBA1 glucosylceramidase beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:42,317,704...42,322,285
Ensembl chr 7:42,317,862...42,322,864 		JBrowse link
G GBA2 glucosylceramidase beta 2 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr11:52,264,959...52,277,298
Ensembl chr11:52,265,070...52,277,213 		JBrowse link
G GBA3 glucosylceramidase beta 3 involved_in
NOT|involved_in		 ISO (PMID:26724485)
(PMID:20728381)
(PMID:17595169)		 UniProt PMID:17595169 PMID:20728381 PMID:26724485 NCBI chr 3:87,080,351...87,190,931
Ensembl chr 3:87,081,134...87,190,987 		JBrowse link
glucosylceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GBA1 glucosylceramidase beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17954912), (PMID:18346921) Ensembl
MGI		 PMID:17954912 PMID:18346921 GO_REF:0000107 NCBI chr 7:42,317,704...42,322,285
Ensembl chr 7:42,317,862...42,322,864 		JBrowse link
G PSAP prosaposin acts_upstream_of_or_within ISO (PMID:17353235) MGI PMID:17353235 NCBI chr 4:22,571,095...22,603,880
Ensembl chr 4:22,572,153...22,603,848 		JBrowse link
glycosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLA galactosidase alpha acts_upstream_of_or_within ISO (PMID:10841515), (PMID:11752062), (PMID:9122231)
(PMID:10840053), (PMID:15629890)		 MGI PMID:9122231 PMID:10840053 PMID:10841515 PMID:11752062 PMID:15629890 NCBI chr  X:75,311,536...75,320,391
Ensembl chr  X:75,311,536...75,320,249 		JBrowse link
G LCT lactase involved_in ISO PMID:4752949 UniProt PMID:4752949 RGD:151356630 NCBI chr19:38,571,539...38,620,567
Ensembl chr19:38,572,058...38,620,567 		JBrowse link
glycosylceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ST6GALNAC3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:70,060,406...70,583,974
Ensembl chr 6:70,062,555...70,574,865 		JBrowse link
G ST6GALNAC6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:55,520,083...55,533,205
Ensembl chr 9:55,520,109...55,532,055 		JBrowse link
lactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4GALT4 beta-1,4-galactosyltransferase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr33:22,903,842...22,920,955
Ensembl chr33:22,904,149...22,920,956 		JBrowse link
G B4GALT6 beta-1,4-galactosyltransferase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:57,849,872...57,917,289
Ensembl chr 7:57,849,884...57,914,360 		JBrowse link
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431) MGI
Ensembl		 PMID:25691431 GO_REF:0000107 NCBI chr37:509,592...521,511
Ensembl chr37:511,149...522,865 		JBrowse link
G ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 acts_upstream_of_or_within ISO (PMID:25691431) MGI PMID:25691431 NCBI chr10:203,750...206,247 JBrowse link
G ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431) MGI
Ensembl		 PMID:25691431 GO_REF:0000107 NCBI chr 9:22,594,425...22,601,108
Ensembl chr 9:22,594,480...22,599,999 		JBrowse link
G SPHK1 sphingosine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:4,311,698...4,314,773
Ensembl chr 9:4,311,683...4,314,483 		JBrowse link
omega-hydroxyceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PNPLA1 patatin like phospholipase domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:5,377,430...5,423,556
Ensembl chr12:5,377,430...5,423,556 		JBrowse link
positive regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCN1 cellular communication network factor 1 acts_upstream_of_or_within ISO (PMID:19364818) MGI PMID:19364818 NCBI chr 6:62,443,285...62,446,246
Ensembl chr 6:62,443,675...62,445,994 		JBrowse link
G ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISO (MGI:4947032|PMID:21177474) UniProt PMID:21177474 MGI:4947032 NCBI chr 9:1,887,093...1,894,728
Ensembl chr 9:1,887,201...1,897,473 		JBrowse link
G PLA2G6 phospholipase A2 group VI ISO RGD PMID:18936091 RGD:6482750 NCBI chr10:26,499,033...26,559,533
Ensembl chr10:26,509,695...26,634,087 		JBrowse link
G PRKCD protein kinase C delta involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:36,723,491...36,751,982
Ensembl chr20:36,723,809...36,752,191 		JBrowse link
G SIRT3 sirtuin 3 involved_in ISO (MGI:5755322|PMID:26620563) UniProt PMID:26620563 MGI:5755322 NCBI chr18:25,369,183...25,388,126
Ensembl chr18:25,369,382...25,388,118 		JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 ISO RGD PMID:20096352 RGD:10041064 NCBI chr 5:81,089,657...81,172,173
Ensembl chr 5:81,142,888...81,172,189 		JBrowse link
G SPHK2 sphingosine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:107,681,425...107,689,790
Ensembl chr 1:107,680,599...107,689,707 		JBrowse link
G ZNF750 zinc finger protein 750 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:37115925) Ensembl
MGI		 PMID:37115925 GO_REF:0000107
positive regulation of glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKCD protein kinase C delta involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:36,723,491...36,751,982
Ensembl chr20:36,723,809...36,752,191 		JBrowse link
regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:31880535) UniProt
MGI
Ensembl		 PMID:31880535 GO_REF:0000104 GO_REF:0000107 GO_REF:0000117 NCBI chr37:509,592...521,511
Ensembl chr37:511,149...522,865 		JBrowse link
G ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 involved_in IEA UniProt GO_REF:0000104 GO_REF:0000117 NCBI chr10:203,750...206,247 JBrowse link
G ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:31880535) Ensembl
MGI
UniProt		 PMID:31880535 GO_REF:0000104 GO_REF:0000107 GO_REF:0000117 NCBI chr 9:22,594,425...22,601,108
Ensembl chr 9:22,594,480...22,599,999 		JBrowse link
G PAQR4 progestin and adipoQ receptor family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:38,210,476...38,213,689
Ensembl chr 6:38,210,481...38,213,670 		JBrowse link
G PRKCD protein kinase C delta involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr20:36,723,491...36,751,982
Ensembl chr20:36,723,809...36,752,191 		JBrowse link
G SAMD8 sterile alpha motif domain containing 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:25,375,127...25,424,792
Ensembl chr 4:25,374,837...25,421,075 		JBrowse link
regulation of glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR127 microRNA mir-127 acts_upstream_of ISO (PMID:25584808) ARUK-UCL PMID:25584808 NCBI chr 8:69,104,938...69,104,997
Ensembl chr 8:69,104,906...69,105,016 		JBrowse link
G MIR16-1 microRNA mir-16-1 acts_upstream_of_or_within ISO (PMID:25584808) ARUK-UCL PMID:25584808 NCBI chr22:1,847,020...1,847,084
Ensembl chr22:1,847,007...1,847,093 		JBrowse link
G MIR16-2 microRNA mir-16-2 acts_upstream_of_or_within ISO (PMID:25584808) ARUK-UCL PMID:25584808 NCBI chr34:26,460,807...26,460,871
Ensembl chr34:26,460,807...26,460,871 		JBrowse link
G MIR195 microRNA mir-195 acts_upstream_of_or_within ISO (PMID:25584808) ARUK-UCL PMID:25584808 NCBI chr 5:32,045,450...32,045,510
Ensembl chr 5:32,045,450...32,045,510 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17068
    metabolic process 10854
      amide metabolic process 419
        ceramide metabolic process 102
          ceramide biosynthetic process + 64
          ceramide catabolic process + 24
          ganglioside metabolic process + 22
          glycosylceramide metabolic process + 21
          lactosylceramide metabolic process + 2
Path 2
Term Annotations click to browse term
  biological_process 17068
    metabolic process 10854
      primary metabolic process 9582
        lipid metabolic process 1264
          cellular lipid metabolic process 911
            membrane lipid metabolic process 189
              sphingolipid metabolic process 138
                ceramide metabolic process 102
                  ceramide biosynthetic process + 64
                  ceramide catabolic process + 24
                  ganglioside metabolic process + 22
                  glycosylceramide metabolic process + 21
                  lactosylceramide metabolic process + 2
paths to the root