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ONTOLOGY REPORT - ANNOTATIONS

Term:ceramide metabolic process
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Accession:GO:0006672 term browser browse the term
Definition:The chemical reactions and pathways involving ceramides, any N-acylated sphingoid.
Synonyms:exact_synonym: ceramide metabolism

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ceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca12 ATP binding cassette subfamily A member 12 involved_in ISO (PMID:17927575)
(MGI:4462766|PMID:20489143)		 UniProt PMID:17927575 PMID:20489143 MGI:4462766 NCBI chrNW_004955457:885,941...1,062,713
Ensembl chrNW_004955457:879,510...1,062,713 		JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in ISO (PMID:26190575) UniProt PMID:26190575 NCBI chrNW_004955425:5,840,355...5,931,891
Ensembl chrNW_004955425:5,840,355...5,931,891 		JBrowse link
G Cerk ceramide kinase involved_in ISO (PMID:19501188) UniProt PMID:19501188 NCBI chrNW_004955413:30,658,472...30,693,948
Ensembl chrNW_004955413:30,660,593...30,679,674 		JBrowse link
G Cert1 ceramide transporter 1 acts_upstream_of_or_within ISO (PMID:19139267) MGI PMID:19139267 NCBI chrNW_004955425:25,228,216...25,355,597
Ensembl chrNW_004955425:25,233,556...25,357,802 		JBrowse link
G Cln8 CLN8 transmembrane ER and ERGIC protein involved_in ISO (PMID:16086686) UniProt PMID:16086686 NCBI chrNW_004955403:57,926,711...57,938,698
Ensembl chrNW_004955403:57,924,873...57,938,690 		JBrowse link
G Fut7 fucosyltransferase 7 involved_in ISO (PMID:9299472) BHF-UCL PMID:9299472 NCBI chrNW_004955513:5,056,718...5,061,974 JBrowse link
G Htra2 HtrA serine peptidase 2 ISO C2 ceramide RGD PMID:22296759 RGD:5688365 NCBI chrNW_004955424:11,255,756...11,259,170
Ensembl chrNW_004955424:11,255,756...11,259,170 		JBrowse link
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 involved_in ISO (PMID:20182505) UniProt PMID:20182505 NCBI chrNW_004955403:9,100,516...9,113,230
Ensembl chrNW_004955403:9,100,516...9,113,223 		JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 involved_in ISO (PMID:20182505) UniProt PMID:20182505 NCBI chrNW_004955458:3,451,434...3,454,259
Ensembl chrNW_004955458:3,451,021...3,457,086 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 involved_in ISO (PMID:20182505) UniProt PMID:20182505 NCBI chrNW_004955451:14,621,565...14,627,556
Ensembl chrNW_004955451:14,621,399...14,642,763 		JBrowse link
G Pla2g15 phospholipase A2 group XV involved_in
acts_upstream_of_or_within		 ISO (PMID:20410020), (PMID:29724779)
(PMID:11790796)
PMID:15294901
(MGI:3694368|PMID:16837646), (MGI:4820669|PMID:20410020)		 UniProt
MGI		 PMID:11790796 PMID:15294901 PMID:16837646 PMID:20410020 PMID:29724779 MGI:3694368 MGI:4820669 RGD:1304489 NCBI chrNW_004955484:8,386,274...8,412,952
Ensembl chrNW_004955484:8,386,274...8,412,952 		JBrowse link
G Plpp1 phospholipid phosphatase 1 involved_in ISO PMID:8663293
(MGI:6383560|PMID:10359651)
(PMID:9305923), (PMID:9705349)		 UniProt PMID:8663293 PMID:9305923 PMID:9705349 PMID:10359651 MGI:6383560 RGD:15090855 RGD:15090857 NCBI chrNW_004955446:12,201,678...12,279,992
Ensembl chrNW_004955446:12,229,395...12,279,737 		JBrowse link
G Plpp2 phospholipid phosphatase 2 involved_in ISO (PMID:9705349) UniProt PMID:9705349 NCBI chrNW_004955495:7,307,079...7,310,898
Ensembl chrNW_004955495:7,307,079...7,310,955 		JBrowse link
G Plpp3 phospholipid phosphatase 3 involved_in ISO (PMID:9305923), (PMID:9705349) UniProt PMID:9305923 PMID:9705349 NCBI chrNW_004955464:3,122,420...3,197,359
Ensembl chrNW_004955464:3,081,334...3,197,413 		JBrowse link
G Psap prosaposin acts_upstream_of_or_within ISO (PMID:17353235)
(PMID:15345707)		 MGI PMID:15345707 PMID:17353235 NCBI chrNW_004955437:19,667,252...19,683,669 JBrowse link
G Sgpl1 sphingosine-1-phosphate lyase 1 involved_in ISO (PMID:14570870) UniProt PMID:14570870 NCBI chrNW_004955437:20,489,641...20,547,105
Ensembl chrNW_004955437:20,488,330...20,547,171 		JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 acts_upstream_of_or_within ISO (PMID:23046545) MGI PMID:23046545 NCBI chrNW_004955414:22,117,929...22,121,744
Ensembl chrNW_004955414:22,117,930...22,121,744 		JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 involved_in ISO (PMID:9520418) MGI PMID:9520418 NCBI chrNW_004955411:34,481,431...34,484,423
Ensembl chrNW_004955411:34,481,823...34,484,406 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 acts_upstream_of_or_within ISO (PMID:22383528), (PMID:23046545) MGI PMID:22383528 PMID:23046545 NCBI chrNW_004955484:8,207,686...8,298,164
Ensembl chrNW_004955484:8,272,572...8,298,144 		JBrowse link
G Tm9sf2 transmembrane 9 superfamily member 2 involved_in ISO (PMID:30660999) UniProt PMID:30660999 NCBI chrNW_004955404:11,071,716...11,128,758
Ensembl chrNW_004955404:11,069,843...11,129,056 		JBrowse link
ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agk acylglycerol kinase acts_upstream_of_or_within ISO (PMID:15252046) MGI PMID:15252046 NCBI chrNW_004955494:1,924,026...2,041,914
Ensembl chrNW_004955494:1,924,026...2,021,778 		JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type involved_in ISO (MGI:3789553|PMID:17403930) UniProt PMID:17403930 MGI:3789553 NCBI chrNW_004955467:8,876,186...8,887,980
Ensembl chrNW_004955467:8,876,027...8,888,033 		JBrowse link
G Aloxe3 arachidonate epidermal lipoxygenase 3 involved_in
acts_upstream_of_or_within		 ISO (MGI:5488571|PMID:22832496)
(PMID:22832496)		 UniProt
MGI		 PMID:22832496 MGI:5488571 NCBI chrNW_004955467:8,844,805...8,869,230
Ensembl chrNW_004955467:8,844,805...8,869,964 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 involved_in ISO (PMID:12764132), (PMID:12815059) UniProt PMID:12764132 PMID:12815059 NCBI chrNW_004955552:1,623,263...1,660,285
Ensembl chrNW_004955552:1,623,738...1,659,086 		JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in ISO (PMID:17475390)
(MGI:6274955|PMID:21613224)
PMID:15123644
PMID:11278489
(PMID:11278489)		 UniProt PMID:11278489 PMID:15123644 PMID:17475390 PMID:21613224 MGI:6274955 RGD:13838793 RGD:13838803 NCBI chrNW_004955425:5,840,355...5,931,891
Ensembl chrNW_004955425:5,840,355...5,931,891 		JBrowse link
G Cers1 ceramide synthase 1 involved_in ISO (MGI:3696321|PMID:16951403), (MGI:3764760|PMID:17977534), (MGI:5755322|PMID:26620563)
(MGI:5008665|PMID:21625621), (MGI:6380950|PMID:30605666)
(PMID:12105227), (PMID:12869556), (PMID:15823095), (PMID:17548428), (PMID:18541923), (PMID:22922758), (PMID:24782409)		 UniProt PMID:12105227 PMID:12869556 PMID:15823095 PMID:16951403 PMID:17548428 More... MGI:3696321 MGI:3764760 MGI:5008665 MGI:5755322 MGI:6380950 NCBI chrNW_004955524:2,788,672...2,798,068
Ensembl chrNW_004955524:2,788,653...2,796,370 		JBrowse link
G Cers2 ceramide synthase 2 involved_in
acts_upstream_of_or_within		 ISO (PMID:17977534), (PMID:18165233), (PMID:29632068)
(PMID:15823095)
(MGI:4421488|PMID:19801672)
(MGI:5755322|PMID:26620563)		 UniProt
MGI		 PMID:15823095 PMID:17977534 PMID:18165233 PMID:19801672 PMID:26620563 More... MGI:4421488 MGI:5755322 NCBI chrNW_004955588:338,381...342,139
Ensembl chrNW_004955588:336,083...342,599 		JBrowse link
G Cers3 ceramide synthase 3 involved_in ISO (PMID:17977534), (PMID:22038835)
(MGI:5303015|PMID:22038835)
(PMID:23754960)		 UniProt PMID:17977534 PMID:22038835 PMID:23754960 MGI:5303015 NCBI chrNW_004955416:27,461,950...27,577,145
Ensembl chrNW_004955416:27,461,335...27,536,188 		JBrowse link
G Cers4 ceramide synthase 4 involved_in
acts_upstream_of_or_within		 ISO (PMID:17977534), (PMID:29632068)
(PMID:12912983), (PMID:15823095)		 UniProt
MGI		 PMID:12912983 PMID:15823095 PMID:17977534 PMID:29632068 NCBI chrNW_004955563:1,100,410...1,105,662
Ensembl chrNW_004955563:1,100,787...1,124,258 		JBrowse link
G Cers5 ceramide synthase 5 involved_in ISO (PMID:16951403), (PMID:29632068)
(MGI:3696624|PMID:16100120), (MGI:3722529|PMID:17609214), (MGI:3764760|PMID:17977534)		 UniProt PMID:16100120 PMID:16951403 PMID:17609214 PMID:17977534 PMID:29632068 MGI:3696624 MGI:3722529 MGI:3764760 NCBI chrNW_004955547:697,089...728,573
Ensembl chrNW_004955547:697,089...726,139 		JBrowse link
G Cers6 ceramide synthase 6 involved_in
acts_upstream_of_or_within		 ISO (PMID:17609214), (PMID:17977534)
(PMID:15823095)
(MGI:5755322|PMID:26620563)
(MGI:5513027|PMID:23760501)		 UniProt
MGI		 PMID:15823095 PMID:17609214 PMID:17977534 PMID:23760501 PMID:26620563 MGI:5513027 MGI:5755322 NCBI chrNW_004955449:5,636,678...5,920,377
Ensembl chrNW_004955449:5,642,341...5,920,573 		JBrowse link
G Degs1 delta 4-desaturase, sphingolipid 1 acts_upstream_of_or_within ISO (PMID:22984457) MGI PMID:22984457 NCBI chrNW_004955520:1,139,568...1,143,149
Ensembl chrNW_004955520:1,135,563...1,143,192 		JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 involved_in ISO (MGI:5532629|PMID:23689133) UniProt PMID:23689133 MGI:5532629 NCBI chrNW_004955537:2,945,509...2,950,146
Ensembl chrNW_004955537:2,945,509...2,950,146 		JBrowse link
G Fa2h fatty acid 2-hydroxylase involved_in ISO (PMID:15337768)
(MGI:6245295|PMID:22517924)		 UniProt PMID:15337768 PMID:22517924 MGI:6245295 NCBI chrNW_004955484:2,726,496...2,775,763
Ensembl chrNW_004955484:2,726,362...2,775,903 		JBrowse link
G Gba1 glucosylceramidase beta 1 involved_in ISO (PMID:19279011) BHF-UCL PMID:19279011 NCBI chrNW_004955545:1,682,097...1,689,373
Ensembl chrNW_004955545:1,682,097...1,689,376 		JBrowse link
G LOC102004294 cytochrome P450 4F22 involved_in ISO (PMID:26056268) UniProt PMID:26056268 NCBI chrNW_004955495:7,730,881...7,763,684
Ensembl chrNW_004955495:7,730,826...7,763,684 		JBrowse link
G Mecr mitochondrial trans-2-enoyl-CoA reductase acts_upstream_of ISO (PMID:37653044) UniProt PMID:37653044 NCBI chrNW_004955452:8,185,550...8,218,711
Ensembl chrNW_004955452:8,185,550...8,218,950 		JBrowse link
G P2rx1 purinergic receptor P2X 1 acts_upstream_of_or_within ISO (PMID:16325464) MGI PMID:16325464 NCBI chrNW_004955467:12,955,663...12,971,547
Ensembl chrNW_004955467:12,955,672...12,971,547 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:16325464) MGI PMID:16325464 NCBI chrNW_004955482:7,048,674...7,087,525
Ensembl chrNW_004955482:7,048,776...7,086,926 		JBrowse link
G Pnpla1 patatin like phospholipase domain containing 1 involved_in ISO (PMID:27751867)
(MGI:5882269|PMID:27751867)		 UniProt PMID:27751867 MGI:5882269 NCBI chrNW_004955437:4,008,814...4,047,895
Ensembl chrNW_004955437:4,008,545...4,048,033 		JBrowse link
G Samd8 sterile alpha motif domain containing 8 involved_in
acts_upstream_of_or_within		 ISO (PMID:19506037)
(PMID:25667419)
(PMID:25605874)
(PMID:25605874), (PMID:25667419)		 UniProt
MGI		 PMID:19506037 PMID:25605874 PMID:25667419 NCBI chrNW_004955437:16,900,756...16,969,042
Ensembl chrNW_004955437:16,900,688...16,969,042 		JBrowse link
G Sgms1 sphingomyelin synthase 1 acts_upstream_of_or_within ISO (PMID:25605874) MGI PMID:25605874 NCBI chrNW_004955425:5,507,905...5,819,357
Ensembl chrNW_004955425:5,784,751...5,822,488 		JBrowse link
G Sgms2 sphingomyelin synthase 2 acts_upstream_of_or_within ISO (PMID:25605874) MGI PMID:25605874 NCBI chrNW_004955496:1,909,347...1,955,004
Ensembl chrNW_004955496:1,905,517...1,947,009 		JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 involved_in ISO (PMID:35705808)
(PMID:17303575), (PMID:18815062), (PMID:20807762), (PMID:33163980)
(MGI:82530|PMID:8706124)
(PMID:19279011), (PMID:8706124)		 RGD
UniProt
BHF-UCL		 PMID:8706124 PMID:17261082 PMID:17303575 PMID:18815062 PMID:19279011 More... MGI:82530 RGD:1601344 NCBI chrNW_004955414:22,117,929...22,121,744
Ensembl chrNW_004955414:22,117,930...22,121,744 		JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 ISO RGD PMID:12473648 RGD:1581395 NCBI chrNW_004955411:34,481,431...34,484,423
Ensembl chrNW_004955411:34,481,823...34,484,406 		JBrowse link
G Smpd4 sphingomyelin phosphodiesterase 4 involved_in ISO (PMID:16517606), (PMID:25180167)
(MGI:6450503|PMID:25180167)		 BHF-UCL
UniProt		 PMID:16517606 PMID:25180167 MGI:6450503 NCBI chrNW_004955442:19,184,794...19,210,999
Ensembl chrNW_004955442:19,184,794...19,210,999 		JBrowse link
G Sptlc1 serine palmitoyltransferase long chain base subunit 1 acts_upstream_of_or_within ISO (PMID:25691431)
(PMID:16216550)		 MGI PMID:16216550 PMID:25691431 NCBI chrNW_004955515:57,711...161,012
Ensembl chrNW_004955515:57,711...161,611 		JBrowse link
G Sptlc2 serine palmitoyltransferase long chain base subunit 2 acts_upstream_of_or_within ISO (PMID:25691431)
(PMID:16216550)		 MGI PMID:16216550 PMID:25691431 NCBI chrNW_004955438:1,385,431...1,491,534
Ensembl chrNW_004955438:1,385,431...1,491,578 		JBrowse link
G Sptssa serine palmitoyltransferase small subunit A acts_upstream_of_or_within ISO (PMID:25691431) MGI PMID:25691431 NCBI chrNW_004955409:26,460,208...26,460,854 JBrowse link
G Sptssb serine palmitoyltransferase small subunit B acts_upstream_of_or_within ISO (PMID:26438849) MGI PMID:26438849 NCBI chrNW_004955448:11,756,766...11,791,418
Ensembl chrNW_004955448:11,756,766...11,790,368 		JBrowse link
G Tlcd3b TLC domain containing 3B acts_upstream_of_or_within ISO (PMID:23275342) MGI PMID:23275342 NCBI chrNW_004955493:6,929,477...6,940,109
Ensembl chrNW_004955493:6,929,477...6,942,227 		JBrowse link
ceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer1 alkaline ceramidase 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:20207939)
(PMID:12783875)
(MGI:5800647|PMID:27126290)		 UniProt
MGI		 PMID:12783875 PMID:20207939 PMID:27126290 MGI:5800647 NCBI chrNW_004955495:3,247,170...3,271,417
Ensembl chrNW_004955495:3,247,083...3,271,720 		JBrowse link
G Acer2 alkaline ceramidase 2 involved_in ISO (PMID:16940153), (PMID:20207939) UniProt PMID:16940153 PMID:20207939 NCBI chrNW_004955434:21,786,857...21,810,648
Ensembl chrNW_004955434:21,786,856...21,810,648 		JBrowse link
G Acer3 alkaline ceramidase 3 involved_in ISO (PMID:20207939), (PMID:26792856)
(MGI:5749603|PMID:26474409)
(PMID:30575723)		 UniProt PMID:20207939 PMID:26474409 PMID:26792856 PMID:30575723 MGI:5749603 NCBI chrNW_004955414:14,741,027...14,846,931
Ensembl chrNW_004955414:14,746,529...14,848,151 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 involved_in ISO (PMID:10610716)
(MGI:5505361|PMID:23770692)
(MGI:1267186|PMID:9653654)
(PMID:12815059)		 UniProt PMID:9653654 PMID:10610716 PMID:12815059 PMID:23770692 MGI:1267186 MGI:5505361 NCBI chrNW_004955552:1,623,263...1,660,285
Ensembl chrNW_004955552:1,623,738...1,659,086 		JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in ISO (PMID:10781606), (PMID:15946935), (PMID:19345744), (PMID:30154232)
PMID:15123644
(MGI:3608219|PMID:16126722), (MGI:3640407|PMID:16380386)
(MGI:6275120|PMID:10652340)
PMID:15217782
PMID:10488143
(PMID:16229686), (PMID:17475390)		 UniProt PMID:10488143 PMID:10652340 PMID:10781606 PMID:15123644 PMID:15217782 More... MGI:3608219 MGI:3640407 MGI:6275120 RGD:13838793 RGD:13838794 RGD:13838800 NCBI chrNW_004955425:5,840,355...5,931,891
Ensembl chrNW_004955425:5,840,355...5,931,891 		JBrowse link
G Cel carboxyl ester lipase acts_upstream_of_or_within ISO (PMID:11733511) MGI PMID:11733511 NCBI chrNW_004955513:2,324,025...2,382,877 JBrowse link
galactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3galt1 beta-1,3-galactosyltransferase 1 involved_in ISO (PMID:9582303) BHF-UCL PMID:9582303 NCBI chrNW_004955449:6,452,189...7,007,329
Ensembl chrNW_004955449:6,452,189...6,553,158 		JBrowse link
G B3galt2 beta-1,3-galactosyltransferase 2 involved_in ISO (PMID:9582303) BHF-UCL PMID:9582303 NCBI chrNW_004955406:30,603,238...30,610,822
Ensembl chrNW_004955406:30,603,238...30,610,822 		JBrowse link
G B4galt3 beta-1,4-galactosyltransferase 3 involved_in ISO (PMID:9405390) BHF-UCL PMID:9405390 NCBI chrNW_004955468:12,934,521...12,945,435
Ensembl chrNW_004955468:12,932,059...12,940,723 		JBrowse link
G Fa2h fatty acid 2-hydroxylase involved_in ISO PMID:17901466
(MGI:3826747|PMID:18815260)
(MGI:3696647|PMID:15658937)		 UniProt PMID:15658937 PMID:17901466 PMID:18815260 MGI:3696647 MGI:3826747 RGD:13825191 NCBI chrNW_004955484:2,726,496...2,775,763
Ensembl chrNW_004955484:2,726,362...2,775,903 		JBrowse link
G Gal3st1 galactose-3-O-sulfotransferase 1 acts_upstream_of_or_within ISO (PMID:10727929) MGI PMID:10727929 NCBI chrNW_004955455:4,771,378...4,794,085
Ensembl chrNW_004955455:4,771,346...4,784,142 		JBrowse link
G Ugt8 UDP glycosyltransferase 8 involved_in ISO PMID:8713090 UniProt PMID:8713090 RGD:39458006 NCBI chrNW_004955428:24,800,854...24,864,904
Ensembl chrNW_004955428:24,800,854...24,865,378 		JBrowse link
galactosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Galc galactosylceramidase involved_in
acts_upstream_of_or_within		 ISO (PMID:8399327)
(PMID:11371512)
(MGI:78941|PMID:8769874)		 UniProt
MGI		 PMID:8399327 PMID:8769874 PMID:11371512 MGI:78941 NCBI chrNW_004955438:10,667,807...10,704,386
Ensembl chrNW_004955438:10,667,807...10,704,384 		JBrowse link
G Psap prosaposin acts_upstream_of_or_within ISO (PMID:11371512) MGI PMID:11371512 NCBI chrNW_004955437:19,667,252...19,683,669 JBrowse link
galactosylceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gal3st1 galactose-3-O-sulfotransferase 1 involved_in ISO (MGI:6436415|PMID:9030544) UniProt PMID:9030544 MGI:6436415 NCBI chrNW_004955455:4,771,378...4,794,085
Ensembl chrNW_004955455:4,771,346...4,784,142 		JBrowse link
ganglioside biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3galt4 beta-1,3-galactosyltransferase 4 involved_in ISO (PMID:9582303) BHF-UCL PMID:9582303 NCBI chrNW_004955437:1,839,707...1,840,516 JBrowse link
G B4galnt1 beta-1,4-N-acetyl-galactosaminyltransferase 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:7487055), (PMID:7890749)
(PMID:10021458)
(MGI:83232|PMID:8855236)
PMID:3140234
(PMID:1601877)		 UniProt
MGI		 PMID:1601877 PMID:3140234 PMID:7487055 PMID:7890749 PMID:8855236 More... MGI:83232 RGD:21201261 NCBI chrNW_004955458:5,351,924...5,361,755
Ensembl chrNW_004955458:5,350,244...5,360,965 		JBrowse link
G St6galnac6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 acts_upstream_of_or_within ISO (PMID:10702226) MGI PMID:10702226 NCBI chrNW_004955419:771,721...792,756
Ensembl chrNW_004955419:772,837...796,724 		JBrowse link
G St8sia2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 involved_in ISO (PMID:10766765) BHF-UCL PMID:10766765 NCBI chrNW_004955416:20,697,651...20,763,975
Ensembl chrNW_004955416:20,697,651...20,767,112 		JBrowse link
G St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 involved_in ISO (PMID:10766765)
(MGI:74245|PMID:7782326)		 BHF-UCL
UniProt		 PMID:7782326 PMID:10766765 MGI:74245 NCBI chrNW_004955402:41,713,969...41,732,889
Ensembl chrNW_004955402:41,713,573...41,723,749 		JBrowse link
G St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 involved_in ISO (PMID:10766765) BHF-UCL PMID:10766765 NCBI chrNW_004955418:12,590,744...12,679,677
Ensembl chrNW_004955418:12,590,536...12,679,677 		JBrowse link
G St8sia6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 involved_in ISO (MGI:2182536|PMID:11980897) BHF-UCL PMID:11980897 MGI:2182536 NCBI chrNW_004955429:10,538,660...10,660,493
Ensembl chrNW_004955429:10,538,661...10,658,008 		JBrowse link
ganglioside biosynthetic process via lactosylceramide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galt5 beta-1,4-galactosyltransferase 5 involved_in ISO (MGI:6196231|PMID:30114188) UniProt PMID:30114188 MGI:6196231 NCBI chrNW_004955445:8,471,684...8,559,672
Ensembl chrNW_004955445:8,534,220...8,559,672 		JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 involved_in ISO (MGI:6196231|PMID:30114188) UniProt PMID:30114188 MGI:6196231 NCBI chrNW_004955402:18,945,013...19,024,132
Ensembl chrNW_004955402:18,942,872...19,024,132 		JBrowse link
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 involved_in ISO (PMID:8027041)
(MGI:65558|PMID:8144500)		 UniProt PMID:8027041 PMID:8144500 MGI:65558 NCBI chrNW_004955461:7,960,901...8,036,221
Ensembl chrNW_004955461:7,960,690...7,976,183 		JBrowse link
G St3gal2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 involved_in ISO (PMID:8920913)
(MGI:6467685|PMID:22735313)
(MGI:65558|PMID:8144500)		 UniProt PMID:8144500 PMID:8920913 PMID:22735313 MGI:6467685 MGI:65558 RGD:68307 NCBI chrNW_004955484:3,176,214...3,230,433
Ensembl chrNW_004955484:3,177,104...3,230,433 		JBrowse link
G St3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 involved_in ISO (MGI:6467685|PMID:22735313) UniProt PMID:22735313 MGI:6467685 NCBI chrNW_004955537:3,258,076...3,458,742
Ensembl chrNW_004955537:3,258,076...3,458,742 		JBrowse link
ganglioside catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gm2a GM2 ganglioside activator acts_upstream_of_or_within ISO (PMID:9223328) MGI PMID:9223328 NCBI chrNW_004955408:2,442,406...2,449,426
Ensembl chrNW_004955408:2,442,406...2,449,426 		JBrowse link
G Hexa hexosaminidase subunit alpha involved_in
acts_upstream_of_or_within		 ISO (PMID:8123671), (PMID:8672428), (PMID:9694901)
(PMID:8789434), (PMID:9645704)
(PMID:7937929), (PMID:9223328)		 UniProt
MGI		 PMID:7937929 PMID:8123671 PMID:8672428 PMID:8789434 PMID:9223328 More... NCBI chrNW_004955450:4,790,342...4,806,862
Ensembl chrNW_004955450:4,790,268...4,806,734 		JBrowse link
G Hexb hexosaminidase subunit beta involved_in
acts_upstream_of_or_within		 ISO (PMID:8123671), (PMID:8672428)
(PMID:10021458), (PMID:12657883), (PMID:12756243), (PMID:15748167), (PMID:9223328)
(PMID:8789434), (PMID:9645704)
(PMID:8566348)		 UniProt
MGI		 PMID:8123671 PMID:8566348 PMID:8672428 PMID:8789434 PMID:9223328 More... NCBI chrNW_004955425:25,942,341...25,961,312
Ensembl chrNW_004955425:25,942,278...25,961,312 		JBrowse link
G Neu2 neuraminidase 2 involved_in ISO (PMID:14613940), (PMID:22228546)
(MGI:1354405|PMID:10713120)		 UniProt PMID:10713120 PMID:14613940 PMID:22228546 MGI:1354405 NCBI chrNW_004955453:3,054,626...3,063,070
Ensembl chrNW_004955453:3,052,297...3,061,791 		JBrowse link
G Neu3 neuraminidase 3 involved_in ISO (PMID:10861246), (PMID:11298736), (PMID:15847605), (PMID:17334392)
(MGI:3040535|PMID:14970224), (MGI:3765376|PMID:17708748), (MGI:6478528|PMID:11696012)		 UniProt PMID:10861246 PMID:11298736 PMID:11696012 PMID:14970224 PMID:15847605 More... MGI:3040535 MGI:3765376 MGI:6478528 NCBI chrNW_004955414:16,783,996...16,798,368
Ensembl chrNW_004955414:16,788,171...16,798,535 		JBrowse link
G Neu4 neuraminidase 4 involved_in ISO (PMID:15213228), (PMID:15847605)
(MGI:4361102|PMID:19506080)		 UniProt PMID:15213228 PMID:15847605 PMID:19506080 MGI:4361102 NCBI chrNW_004955542:66,214...70,456
Ensembl chrNW_004955542:66,174...71,058 		JBrowse link
ganglioside metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 involved_in ISO (MGI:3718765|PMID:17488728) UniProt PMID:17488728 MGI:3718765 NCBI chrNW_004955513:5,035,879...5,051,140
Ensembl chrNW_004955513:5,033,771...5,051,200 		JBrowse link
G Cln6 CLN6 transmembrane ER protein involved_in ISO (PMID:16857350) UniProt PMID:16857350 NCBI chrNW_004955450:7,876,572...7,885,305
Ensembl chrNW_004955450:7,876,522...7,886,581 		JBrowse link
G Gm2a GM2 ganglioside activator ISO RGD PMID:9770472 RGD:1598995 NCBI chrNW_004955408:2,442,406...2,449,426
Ensembl chrNW_004955408:2,442,406...2,449,426 		JBrowse link
G Itgb8 integrin subunit beta 8 acts_upstream_of_or_within ISO (PMID:16251442) MGI PMID:16251442 NCBI chrNW_004955410:23,011,874...23,099,191
Ensembl chrNW_004955410:23,011,973...23,097,021 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO (PMID:21408219) MGI PMID:21408219 NCBI chrNW_004955451:16,445,338...16,449,243
Ensembl chrNW_004955451:16,445,338...16,450,062 		JBrowse link
glucosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fa2h fatty acid 2-hydroxylase involved_in ISO (MGI:5285470|PMID:21628453) UniProt PMID:21628453 MGI:5285470 NCBI chrNW_004955484:2,726,496...2,775,763
Ensembl chrNW_004955484:2,726,362...2,775,903 		JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase involved_in ISO (PMID:8643456)
(MGI:2180222|PMID:10430909), (MGI:3603060|PMID:16109770), (MGI:5448789|PMID:22851168), (MGI:5510915|PMID:23748427)		 UniProt PMID:8643456 PMID:10430909 PMID:16109770 PMID:22851168 PMID:23748427 MGI:2180222 MGI:3603060 MGI:5448789 MGI:5510915 NCBI chrNW_004955419:15,417,468...15,451,936
Ensembl chrNW_004955419:15,416,796...15,451,936 		JBrowse link
glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba1 glucosylceramidase beta 1 involved_in ISO (PMID:16293621), (PMID:24211208), (PMID:9201993)
(PMID:19279011), (PMID:21700325), (PMID:24022302), (PMID:25584808)
(MGI:6271235|PMID:24211208)
(MGI:5141165|PMID:21700325), (MGI:5501380|PMID:23707074)		 UniProt
ParkinsonsUK-UCL		 PMID:9201993 PMID:16293621 PMID:19279011 PMID:21700325 PMID:23707074 More... MGI:5141165 MGI:5501380 MGI:6271235 NCBI chrNW_004955545:1,682,097...1,689,373
Ensembl chrNW_004955545:1,682,097...1,689,376 		JBrowse link
G Gba2 glucosylceramidase beta 2 involved_in ISO (PMID:17080196)
(MGI:5484792|PMID:23250757)
(MGI:3690511|PMID:17080196)
(PMID:30308956)		 UniProt PMID:17080196 PMID:23250757 PMID:30308956 MGI:3690511 MGI:5484792 NCBI chrNW_004955472:553,556...564,411
Ensembl chrNW_004955472:553,556...564,411 		JBrowse link
glucosylceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba1 glucosylceramidase beta 1 acts_upstream_of_or_within ISO (PMID:17954912), (PMID:18346921) MGI PMID:17954912 PMID:18346921 NCBI chrNW_004955545:1,682,097...1,689,373
Ensembl chrNW_004955545:1,682,097...1,689,376 		JBrowse link
G Psap prosaposin acts_upstream_of_or_within ISO (PMID:17353235) MGI PMID:17353235 NCBI chrNW_004955437:19,667,252...19,683,669 JBrowse link
glycosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gla galactosidase alpha acts_upstream_of_or_within ISO (PMID:10841515), (PMID:11752062), (PMID:9122231)
(PMID:10840053), (PMID:15629890)		 MGI PMID:9122231 PMID:10840053 PMID:10841515 PMID:11752062 PMID:15629890 NCBI chrNW_004955503:7,526,077...7,535,817
Ensembl chrNW_004955503:7,521,930...7,535,817 		JBrowse link
G Lct lactase involved_in ISO PMID:4752949 UniProt PMID:4752949 RGD:151356630 NCBI chrNW_004955440:3,148,730...3,197,110
Ensembl chrNW_004955440:3,148,730...3,197,110 		JBrowse link
glycosylceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G St6galnac3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 involved_in ISO (PMID:17123352) BHF-UCL PMID:17123352 NCBI chrNW_004955423:16,405,309...16,916,163
Ensembl chrNW_004955423:16,406,780...16,916,121 		JBrowse link
G St6galnac6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 involved_in ISO (PMID:17123352) BHF-UCL PMID:17123352 NCBI chrNW_004955419:771,721...792,756
Ensembl chrNW_004955419:772,837...796,724 		JBrowse link
lactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galt4 beta-1,4-galactosyltransferase 4 involved_in ISO (PMID:9792633) UniProt PMID:9792633 NCBI chrNW_004955427:18,964,578...18,982,090
Ensembl chrNW_004955427:18,963,396...18,985,479 		JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 involved_in ISO (PMID:10320813) BHF-UCL PMID:10320813 NCBI chrNW_004955402:18,945,013...19,024,132
Ensembl chrNW_004955402:18,942,872...19,024,132 		JBrowse link
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of_or_within ISO (PMID:25691431) MGI PMID:25691431 NCBI chrNW_004955403:9,100,516...9,113,230
Ensembl chrNW_004955403:9,100,516...9,113,223 		JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 acts_upstream_of_or_within ISO (PMID:25691431) MGI PMID:25691431 NCBI chrNW_004955458:3,451,434...3,454,259
Ensembl chrNW_004955458:3,451,021...3,457,086 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of_or_within ISO (PMID:25691431) MGI PMID:25691431 NCBI chrNW_004955451:14,621,565...14,627,556
Ensembl chrNW_004955451:14,621,399...14,642,763 		JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISO (PMID:16118219)
(MGI:6294167|PMID:16118219)		 UniProt PMID:16118219 MGI:6294167 NCBI chrNW_004955506:5,902,079...5,906,639
Ensembl chrNW_004955506:5,902,345...5,904,988 		JBrowse link
omega-hydroxyceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnpla1 patatin like phospholipase domain containing 1 involved_in ISO (PMID:28248318)
(MGI:5888934|PMID:28248300)		 UniProt PMID:28248300 PMID:28248318 MGI:5888934 NCBI chrNW_004955437:4,008,814...4,047,895
Ensembl chrNW_004955437:4,008,545...4,048,033 		JBrowse link
positive regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn1 cellular communication network factor 1 acts_upstream_of_or_within ISO (PMID:19364818) MGI PMID:19364818 NCBI chrNW_004955423:8,416,498...8,419,029
Ensembl chrNW_004955423:8,413,725...8,419,166 		JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISO (MGI:4947032|PMID:21177474) UniProt PMID:21177474 MGI:4947032 NCBI chrNW_004955506:3,151,133...3,154,613
Ensembl chrNW_004955506:3,151,133...3,154,613 		JBrowse link
G Pla2g6 phospholipase A2 group VI ISO RGD PMID:18936091 RGD:6482750 NCBI chrNW_004955413:24,431,592...24,482,229
Ensembl chrNW_004955413:24,429,589...24,482,537 		JBrowse link
G Prkcd protein kinase C delta involved_in ISO (PMID:19279011) BHF-UCL PMID:19279011 NCBI chrNW_004955430:3,125,066...3,151,857
Ensembl chrNW_004955430:3,124,738...3,153,274 		JBrowse link
G Sirt3 sirtuin 3 involved_in ISO (MGI:5755322|PMID:26620563) UniProt PMID:26620563 MGI:5755322 NCBI chrNW_004955476:11,794,951...11,826,244
Ensembl chrNW_004955476:11,794,951...11,826,237 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 ISO RGD PMID:20096352 RGD:10041064 NCBI chrNW_004955484:8,207,686...8,298,164
Ensembl chrNW_004955484:8,272,572...8,298,144 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO (PMID:16118219)
(MGI:6294167|PMID:16118219)		 UniProt PMID:16118219 MGI:6294167 NCBI chrNW_004955559:1,921,479...1,929,450
Ensembl chrNW_004955559:1,917,301...1,928,493 		JBrowse link
G Znf750 zinc finger protein 750 acts_upstream_of_or_within ISO (PMID:37115925) MGI PMID:37115925 NCBI chrNW_004955506:352,616...360,802
Ensembl chrNW_004955506:352,552...363,003 		JBrowse link
positive regulation of glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkcd protein kinase C delta involved_in ISO (PMID:19279011) BHF-UCL PMID:19279011 NCBI chrNW_004955430:3,125,066...3,151,857
Ensembl chrNW_004955430:3,124,738...3,153,274 		JBrowse link
regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of ISO (PMID:31880535) MGI PMID:31880535 NCBI chrNW_004955403:9,100,516...9,113,230
Ensembl chrNW_004955403:9,100,516...9,113,223 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of ISO (PMID:31880535) MGI PMID:31880535 NCBI chrNW_004955451:14,621,565...14,627,556
Ensembl chrNW_004955451:14,621,399...14,642,763 		JBrowse link
G Paqr4 progestin and adipoQ receptor family member 4 involved_in ISO (PMID:32291319), (PMID:38961186) UniProt PMID:32291319 PMID:38961186 NCBI chrNW_004955442:14,373,092...14,375,862
Ensembl chrNW_004955442:14,373,092...14,375,862 		JBrowse link
G Prkcd protein kinase C delta involved_in ISO (PMID:17303575) UniProt PMID:17303575 NCBI chrNW_004955430:3,125,066...3,151,857
Ensembl chrNW_004955430:3,124,738...3,153,274 		JBrowse link
G Samd8 sterile alpha motif domain containing 8 involved_in ISO (PMID:19506037) UniProt PMID:19506037 NCBI chrNW_004955437:16,900,756...16,969,042
Ensembl chrNW_004955437:16,900,688...16,969,042 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12483
    metabolic process 7924
      amide metabolic process 331
        ceramide metabolic process 95
          ceramide biosynthetic process + 63
          ceramide catabolic process + 19
          ganglioside metabolic process + 22
          glycosylceramide metabolic process + 16
          lactosylceramide metabolic process + 2
Path 2
Term Annotations click to browse term
  biological_process 12483
    metabolic process 7924
      primary metabolic process 6989
        lipid metabolic process 994
          cellular lipid metabolic process 747
            membrane lipid metabolic process 168
              sphingolipid metabolic process 126
                ceramide metabolic process 95
                  ceramide biosynthetic process + 63
                  ceramide catabolic process + 19
                  ganglioside metabolic process + 22
                  glycosylceramide metabolic process + 16
                  lactosylceramide metabolic process + 2
paths to the root