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ONTOLOGY REPORT - ANNOTATIONS

Term:ceramide metabolic process
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Accession:GO:0006672 term browser browse the term
Definition:The chemical reactions and pathways involving ceramides, any N-acylated sphingoid.
Synonyms:exact_synonym: ceramide metabolism


show annotations for term's descendants           Sort by:
ceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA12 ATP binding cassette subfamily A member 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:102,194,286...102,401,175
Ensembl chr2B:220,668,957...220,873,566 		JBrowse link
G ACER1 alkaline ceramidase 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr19:5,327,251...5,393,587
Ensembl chr19:6,252,300...6,281,016 		JBrowse link
G ACER2 alkaline ceramidase 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 9:19,216,891...19,262,477
Ensembl chr 9:19,709,402...19,750,896 		JBrowse link
G ACER3 alkaline ceramidase 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr11:71,911,204...72,077,528
Ensembl chr11:75,557,846...75,717,586 		JBrowse link
G CERK ceramide kinase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr22:26,849,865...26,905,545
Ensembl chr22:45,749,887...45,786,570 		JBrowse link
G CERT1 ceramide transporter 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19139267) Ensembl
MGI		 PMID:19139267 GO_REF:0000107 NCBI chr 5:39,788,858...39,927,626
Ensembl chr 5:40,400,900...40,539,921 		JBrowse link
G CLN8 CLN8 transmembrane ER and ERGIC protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:5,587,875...5,606,883
Ensembl chr 8:1,658,694...1,700,754 		JBrowse link
G FUT3 fucosyltransferase 3 (Lewis blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:4,860,818...4,873,481
Ensembl chr19:5,793,527...5,794,645 		JBrowse link
G FUT5 fucosyltransferase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:4,878,978...4,889,019 JBrowse link
G FUT6 fucosyltransferase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:4,846,423...4,857,328
Ensembl chr19:5,779,200...5,780,389 		JBrowse link
G FUT7 fucosyltransferase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:108,090,793...108,093,513
Ensembl chr 9:137,058,831...137,061,607 		JBrowse link
G HTRA2 HtrA serine peptidase 2 ISO C2 ceramide RGD PMID:22296759 RGD:5688365 NCBI chr2A:74,596,020...74,599,790
Ensembl chr2A:76,102,240...76,106,152 		JBrowse link
G LOC100985247 putative inactive neutral ceramidase B involved_in IEA UniProt GO_REF:0000117 NCBI chr10:46,842,830...46,908,811
Ensembl chr10:48,969,434...49,025,336 		JBrowse link
G ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 involved_in IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr2B:77,076,432...77,090,531
Ensembl chr2B:194,996,437...195,009,102 		JBrowse link
G ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 involved_in IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr12:33,091,020...33,093,794
Ensembl chr12:33,815,514...33,818,669 		JBrowse link
G ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 involved_in IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr17:17,361,624...17,368,194
Ensembl chr17:17,581,612...17,587,741 		JBrowse link
G PLA2G15 phospholipase A2 group XV involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11790796) Ensembl
TreeGrafter
MGI		 PMID:11790796 GO_REF:0000107 GO_REF:0000118 NCBI chr16:48,612,240...48,635,721
Ensembl chr16:68,006,105...68,030,812 		JBrowse link
G PLPP1 phospholipid phosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:58,495,348...58,605,309
Ensembl chr 5:60,160,274...60,227,806 		JBrowse link
G PLPP2 phospholipid phosphatase 2 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr19:238,770...246,004 JBrowse link
G PLPP3 phospholipid phosphatase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:55,779,343...55,862,717
Ensembl chr 1:57,489,178...57,573,398 		JBrowse link
G PSAP prosaposin acts_upstream_of_or_within ISO (PMID:15345707)
(PMID:17353235)		 MGI PMID:15345707 PMID:17353235 NCBI chr10:68,286,359...68,321,349
Ensembl chr10:70,810,881...70,828,781 		JBrowse link
G SGPL1 sphingosine-1-phosphate lyase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:67,286,349...67,351,574
Ensembl chr10:69,812,092...69,876,438 		JBrowse link
G SMPD1 sphingomyelin phosphodiesterase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23046545) Ensembl
MGI		 PMID:23046545 GO_REF:0000107 NCBI chr11:6,521,812...6,526,349 JBrowse link
G SMPD2 sphingomyelin phosphodiesterase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:107,243,751...107,246,941
Ensembl chr 6:111,292,130...111,295,408 		JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22383528), (PMID:23046545) Ensembl
MGI		 PMID:22383528 PMID:23046545 GO_REF:0000107 NCBI chr16:48,734,664...48,825,241
Ensembl chr16:68,131,905...68,142,871 		JBrowse link
G TM9SF2 transmembrane 9 superfamily member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:80,669,277...80,731,340
Ensembl chr13:99,807,555...99,869,456 		JBrowse link
ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGK acylglycerol kinase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15252046) MGI
TreeGrafter		 PMID:15252046 GO_REF:0000118 NCBI chr 7:133,438,436...133,580,423
Ensembl chr 7:145,948,154...146,050,512 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:43,569,858...43,588,039
Ensembl chr17:48,302,450...48,317,029 		JBrowse link
G ALOXE3 arachidonate epidermal lipoxygenase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22832496) Ensembl
MGI		 PMID:22832496 GO_REF:0000107 NCBI chr17:43,539,657...43,562,433
Ensembl chr17:48,271,226...48,293,941 		JBrowse link
G ASAH1 N-acylsphingosine amidohydrolase 1 involved_in ISO (PMID:12764132), (PMID:12815059) UniProt PMID:12764132 PMID:12815059 NCBI chr 8:17,272,632...17,300,902 JBrowse link
G CERS1 ceramide synthase 1 involved_in IEA InterPro
TreeGrafter
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chr19:18,308,265...18,334,892
Ensembl chr19:19,317,173...19,342,487 		JBrowse link
G CERS2 ceramide synthase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15823095) Ensembl
TreeGrafter
MGI
UniProt
InterPro		 PMID:15823095 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chr 1:126,314,483...126,324,312
Ensembl chr 1:129,962,022...129,972,722 		JBrowse link
G CERS3 ceramide synthase 3 involved_in IEA InterPro
TreeGrafter
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chr15:79,128,338...79,272,018
Ensembl chr15:98,422,256...98,521,775 		JBrowse link
G CERS4 ceramide synthase 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12912983), (PMID:15823095) InterPro
TreeGrafter
MGI
UniProt
Ensembl		 PMID:12912983 PMID:15823095 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chr19:7,509,213...7,562,394
Ensembl chr19:8,364,569...8,415,345 		JBrowse link
G CERS5 ceramide synthase 5 involved_in IEA InterPro
TreeGrafter
UniProt
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chr12:38,588,014...38,626,069
Ensembl chr12:39,484,975...39,522,898 		JBrowse link
G CERS6 ceramide synthase 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15823095) InterPro
TreeGrafter
MGI
UniProt
Ensembl		 PMID:15823095 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chr2B:55,711,661...56,036,909
Ensembl chr2B:173,180,436...173,498,553 		JBrowse link
G CYP4F22 cytochrome P450 family 4 subfamily F member 22 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr19:15,039,212...15,083,771
Ensembl chr19:16,041,583...16,068,490 		JBrowse link
G DEGS1 delta 4-desaturase, sphingolipid 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:22984457) MGI
TreeGrafter		 PMID:22984457 GO_REF:0000118 NCBI chr 1:199,651,712...199,661,848
Ensembl chr 1:204,659,389...204,668,901 		JBrowse link
G DEGS2 delta 4-desaturase, sphingolipid 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:80,767,334...80,813,506
Ensembl chr14:100,086,782...100,100,741 		JBrowse link
G ELOVL1 ELOVL fatty acid elongase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:42,664,818...42,686,475
Ensembl chr 1:44,044,693...44,048,769 		JBrowse link
G FA2H fatty acid 2-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:55,278,769...55,340,332
Ensembl chr16:74,632,179...74,693,710 		JBrowse link
G GBA1 glucosylceramidase beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:130,579,300...130,589,560
Ensembl chr 1:134,185,385...134,194,851 		JBrowse link
G LOC100985247 putative inactive neutral ceramidase B involved_in ISO (MGI:6274955|PMID:21613224)
(PMID:17475390)
(PMID:11278489)
PMID:15123644		 UniProt PMID:11278489 PMID:15123644 PMID:17475390 PMID:21613224 MGI:6274955 RGD:13838793 RGD:13838803 NCBI chr10:46,842,830...46,908,811
Ensembl chr10:48,969,434...49,025,336 		JBrowse link
G MECR mitochondrial trans-2-enoyl-CoA reductase acts_upstream_of
involved_in		 ISO
IEA		 (PMID:37653044) UniProt
Ensembl		 PMID:37653044 GO_REF:0000107 NCBI chr 1:28,463,466...28,501,518
Ensembl chr 1:29,490,318...29,527,704 		JBrowse link
G P2RX1 purinergic receptor P2X 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16325464) Ensembl
MGI		 PMID:16325464 GO_REF:0000107 NCBI chr17:3,944,636...3,965,260
Ensembl chr17:3,935,982...3,956,595 		JBrowse link
G P2RX7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:16325464) MGI PMID:16325464 NCBI chr12:118,731,761...118,786,039
Ensembl chr12:122,102,888...122,154,068 		JBrowse link
G PNPLA1 patatin like phospholipase domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:35,828,778...35,872,129
Ensembl chr 6:37,002,466...37,067,190 		JBrowse link
G SAMD8 sterile alpha motif domain containing 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25667419)
(PMID:25605874)
(PMID:25605874), (PMID:25667419)		 Ensembl
TreeGrafter
MGI		 PMID:25605874 PMID:25667419 GO_REF:0000107 GO_REF:0000118 NCBI chr10:71,640,271...71,710,674
Ensembl chr10:74,304,676...74,369,601 		JBrowse link
G SGMS1 sphingomyelin synthase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25605874) MGI
TreeGrafter
Ensembl		 PMID:25605874 GO_REF:0000107 GO_REF:0000118 NCBI chr10:46,960,159...47,273,353
Ensembl chr10:49,076,984...49,116,154 		JBrowse link
G SGMS2 sphingomyelin synthase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25605874) Ensembl
TreeGrafter
MGI		 PMID:25605874 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:100,329,642...100,420,398
Ensembl chr 4:110,936,358...110,992,887 		JBrowse link
G SMPD1 sphingomyelin phosphodiesterase 1 involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:17261082 GO_REF:0000107 GO_REF:0000118 RGD:1601344 NCBI chr11:6,521,812...6,526,349 JBrowse link
G SMPD2 sphingomyelin phosphodiesterase 2 ISO RGD PMID:12473648 RGD:1581395 NCBI chr 6:107,243,751...107,246,941
Ensembl chr 6:111,292,130...111,295,408 		JBrowse link
G SPTLC1 serine palmitoyltransferase long chain base subunit 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431)
(PMID:16216550)		 MGI
TreeGrafter		 PMID:16216550 PMID:25691431 GO_REF:0000118 NCBI chr 9:63,087,798...63,174,977 JBrowse link
G SPTLC2 serine palmitoyltransferase long chain base subunit 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431)
(PMID:16216550)		 MGI
TreeGrafter
Ensembl		 PMID:16216550 PMID:25691431 GO_REF:0000107 GO_REF:0000118 NCBI chr14:58,066,123...58,170,472
Ensembl chr14:77,266,545...77,370,663 		JBrowse link
G SPTLC3 serine palmitoyltransferase long chain base subunit 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:12,966,584...13,125,802
Ensembl chr20:12,952,524...13,111,347 		JBrowse link
G SPTSSA serine palmitoyltransferase small subunit A acts_upstream_of_or_within ISO (PMID:25691431) MGI PMID:25691431 NCBI chr14:15,190,833...15,219,882 JBrowse link
G SPTSSB serine palmitoyltransferase small subunit B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:26438849) Ensembl
TreeGrafter
MGI		 PMID:26438849 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:158,358,718...158,385,625
Ensembl chr 3:166,406,488...166,406,718 		JBrowse link
G TLCD3B TLC domain containing 3B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23275342) Ensembl
TreeGrafter
MGI		 PMID:23275342 GO_REF:0000107 GO_REF:0000118 Ensembl chr16:30,399,815...30,406,663 JBrowse link
ceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACER1 alkaline ceramidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12783875) Ensembl
TreeGrafter
MGI		 PMID:12783875 GO_REF:0000107 GO_REF:0000118 NCBI chr19:5,327,251...5,393,587
Ensembl chr19:6,252,300...6,281,016 		JBrowse link
G ACER2 alkaline ceramidase 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:19,216,891...19,262,477
Ensembl chr 9:19,709,402...19,750,896 		JBrowse link
G ACER3 alkaline ceramidase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:71,911,204...72,077,528
Ensembl chr11:75,557,846...75,717,586 		JBrowse link
G ASAH1 N-acylsphingosine amidohydrolase 1 involved_in ISO (PMID:12815059)
(MGI:1267186|PMID:9653654)
(MGI:5505361|PMID:23770692)
(PMID:10610716)		 UniProt PMID:9653654 PMID:10610716 PMID:12815059 PMID:23770692 MGI:1267186 MGI:5505361 NCBI chr 8:17,272,632...17,300,902 JBrowse link
G CEL carboxyl ester lipase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11733511) Ensembl
TreeGrafter
MGI		 PMID:11733511 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:104,180,310...104,191,434
Ensembl chr 9:132,810,986...132,821,010 		JBrowse link
G LOC100985247 putative inactive neutral ceramidase B involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr10:46,842,830...46,908,811
Ensembl chr10:48,969,434...49,025,336 		JBrowse link
galactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3GALT1 beta-1,3-galactosyltransferase 1 involved_in ISO (PMID:9582303) BHF-UCL PMID:9582303 NCBI chr2B:54,550,248...55,124,358 JBrowse link
G B3GALT2 beta-1,3-galactosyltransferase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:168,638,291...168,645,893
Ensembl chr 1:172,928,889...172,934,683 		JBrowse link
G B4GALT3 beta-1,4-galactosyltransferase 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:136,583,783...136,590,416
Ensembl chr 1:140,496,597...140,503,214 		JBrowse link
G FA2H fatty acid 2-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:55,278,769...55,340,332
Ensembl chr16:74,632,179...74,693,710 		JBrowse link
G GAL3ST1 galactose-3-O-sulfotransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10727929) Ensembl
TreeGrafter
MGI		 PMID:10727929 GO_REF:0000107 GO_REF:0000118 NCBI chr22:11,582,915...11,602,936
Ensembl chr22:29,382,779...29,393,042 		JBrowse link
G UGT8 UDP glycosyltransferase 8 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:107,113,476...107,199,272
Ensembl chr 4:117,676,810...117,762,729 		JBrowse link
galactosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GALC galactosylceramidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11371512) InterPro
TreeGrafter
MGI
Ensembl		 PMID:11371512 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr14:68,545,070...68,605,730
Ensembl chr14:87,905,098...87,965,770 		JBrowse link
G PSAP prosaposin acts_upstream_of_or_within ISO (PMID:11371512) MGI PMID:11371512 NCBI chr10:68,286,359...68,321,349
Ensembl chr10:70,810,881...70,828,781 		JBrowse link
galactosylceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GAL3ST1 galactose-3-O-sulfotransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:11,582,915...11,602,936
Ensembl chr22:29,382,779...29,393,042 		JBrowse link
ganglioside biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3GALT4 beta-1,3-galactosyltransferase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:32,849,358...32,857,140
Ensembl chr 6:33,962,718...33,964,976 		JBrowse link
G B4GALNT1 beta-1,4-N-acetyl-galactosaminyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10021458) Ensembl
TreeGrafter
MGI		 PMID:10021458 GO_REF:0000107 GO_REF:0000118 NCBI chr12:31,293,531...31,303,341
Ensembl chr12:31,553,671...31,562,988 		JBrowse link
G ST6GALNAC3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:75,290,496...75,851,683
Ensembl chr 1:77,377,482...77,930,220 		JBrowse link
G ST6GALNAC4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:99,027,846...99,037,025
Ensembl chr 9:127,699,013...127,708,515 		JBrowse link
G ST6GALNAC5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:76,080,706...76,284,836
Ensembl chr 1:78,167,280...78,366,180 		JBrowse link
G ST6GALNAC6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10702226) Ensembl
TreeGrafter
MGI		 PMID:10702226 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:99,005,336...99,025,296
Ensembl chr 9:127,677,841...127,697,880 		JBrowse link
G ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:71,082,491...71,158,038
Ensembl chr15:90,279,509...90,354,173 		JBrowse link
G ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:50,741,928...50,760,032
Ensembl chr18:54,077,167...54,086,638 		JBrowse link
G ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:96,125,853...96,225,309
Ensembl chr 5:101,795,939...101,891,029 		JBrowse link
G ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:17,632,154...17,771,252
Ensembl chr10:17,909,556...18,041,946 		JBrowse link
ganglioside biosynthetic process via lactosylceramide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4GALT5 beta-1,4-galactosyltransferase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:45,977,801...46,058,429
Ensembl chr20:47,041,469...47,123,214 		JBrowse link
G B4GALT6 beta-1,4-galactosyltransferase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:24,840,106...24,906,309
Ensembl chr18:28,438,302...28,500,946 		JBrowse link
G C21H20orf173 chromosome 21 C20orf173 homolog involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:31,854,431...31,865,921
Ensembl chr20:32,973,857...32,976,541 		JBrowse link
G ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 involved_in IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chr 8:130,111,085...130,227,195
Ensembl chr 8:133,084,835...133,119,791 		JBrowse link
G ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 involved_in IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chr16:54,577,578...54,637,626
Ensembl chr16:70,218,748...70,240,162 		JBrowse link
G ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:43,006,963...43,232,968
Ensembl chr 1:44,409,904...44,603,658 		JBrowse link
ganglioside catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GM2A ganglioside GM2 activator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9223328) InterPro
TreeGrafter
MGI
Ensembl		 PMID:9223328 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:146,680,277...146,696,505
Ensembl chr 5:152,680,696...152,697,018 		JBrowse link
G HEXA hexosaminidase subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8789434), (PMID:9645704)
(PMID:7937929), (PMID:9223328)		 Ensembl
TreeGrafter
MGI		 PMID:7937929 PMID:8789434 PMID:9223328 PMID:9645704 GO_REF:0000107 GO_REF:0000118 NCBI chr15:51,235,123...51,326,832
Ensembl chr15:70,057,943...70,090,688
Ensembl chr15:70,057,943...70,090,688 		JBrowse link
G HEXB hexosaminidase subunit beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8566348)
(PMID:10021458), (PMID:12657883), (PMID:12756243), (PMID:15748167), (PMID:9223328)
(PMID:8789434), (PMID:9645704)		 Ensembl
TreeGrafter
MGI		 PMID:8566348 PMID:8789434 PMID:9223328 PMID:9645704 PMID:10021458 More... GO_REF:0000107 GO_REF:0000118 NCBI chr 5:40,589,448...40,625,176
Ensembl chr 5:41,199,681...41,232,693 		JBrowse link
G LOC117979510 sialidase-4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr2B:129,087,519...129,093,811 JBrowse link
G NEU1 neuraminidase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:31,522,392...31,526,097
Ensembl chr 6:32,409,217...32,412,971 		JBrowse link
G NEU2 neuraminidase 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr2B:120,260,420...120,262,930
Ensembl chr2B:239,174,532...239,176,917 		JBrowse link
G NEU3 neuraminidase 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:70,047,878...70,070,303
Ensembl chr11:73,353,332...73,373,270 		JBrowse link
G NEU4 neuraminidase 4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr12:130,824,179...130,833,287 JBrowse link
ganglioside metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 involved_in ISO (MGI:3718765|PMID:17488728) UniProt PMID:17488728 MGI:3718765 NCBI chr 9:108,067,633...108,089,742
Ensembl chr 9:137,036,696...137,057,776 		JBrowse link
G CLN6 CLN6 transmembrane ER protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:47,156,583...47,215,805
Ensembl chr15:65,425,472...65,985,242 		JBrowse link
G GM2A ganglioside GM2 activator ISO RGD PMID:9770472 RGD:1598995 NCBI chr 5:146,680,277...146,696,505
Ensembl chr 5:152,680,696...152,697,018 		JBrowse link
G ITGB8 integrin subunit beta 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16251442) Ensembl
MGI		 PMID:16251442 GO_REF:0000107 NCBI chr 7:21,019,917...21,105,143
Ensembl chr 7:20,336,031...20,415,666 		JBrowse link
G NAGLU N-acetyl-alpha-glucosaminidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21408219) Ensembl
MGI		 PMID:21408219 GO_REF:0000107 NCBI chr17:14,772,054...14,780,398
Ensembl chr17:14,996,420...15,004,242 		JBrowse link
glucosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FA2H fatty acid 2-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:55,278,769...55,340,332
Ensembl chr16:74,632,179...74,693,710 		JBrowse link
G UGCG UDP-glucose ceramide glucosyltransferase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:83,024,602...83,065,017
Ensembl chr 9:111,184,478...111,222,613 		JBrowse link
glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GBA1 glucosylceramidase beta 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:130,579,300...130,589,560
Ensembl chr 1:134,185,385...134,194,851 		JBrowse link
G GBA2 glucosylceramidase beta 2 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 9:35,587,876...35,599,971
Ensembl chr 9:36,390,409...36,402,949 		JBrowse link
glucosylceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GBA1 glucosylceramidase beta 1 acts_upstream_of_or_within ISO (PMID:17954912), (PMID:18346921) MGI PMID:17954912 PMID:18346921 NCBI chr 1:130,579,300...130,589,560
Ensembl chr 1:134,185,385...134,194,851 		JBrowse link
G PSAP prosaposin acts_upstream_of_or_within ISO (PMID:17353235) MGI PMID:17353235 NCBI chr10:68,286,359...68,321,349
Ensembl chr10:70,810,881...70,828,781 		JBrowse link
glycosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLA galactosidase alpha acts_upstream_of_or_within ISO (PMID:10841515), (PMID:11752062), (PMID:9122231)
(PMID:10840053), (PMID:15629890)		 MGI PMID:9122231 PMID:10840053 PMID:10841515 PMID:11752062 PMID:15629890 NCBI chr  X:90,600,412...90,610,594
Ensembl chr  X:100,732,311...100,742,280 		JBrowse link
G LCT lactase involved_in ISO PMID:4752949 UniProt PMID:4752949 RGD:151356630 NCBI chr2B:24,025,383...24,079,779
Ensembl chr2B:139,855,605...139,908,764 		JBrowse link
G LOC100989541 cytosolic beta-glucosidase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:17,101,362...17,227,184
Ensembl chr 4:22,391,432...22,515,970 		JBrowse link
glycosylceramide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ST6GALNAC3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:75,290,496...75,851,683
Ensembl chr 1:77,377,482...77,930,220 		JBrowse link
G ST6GALNAC6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 involved_in ISO (PMID:17123352) BHF-UCL PMID:17123352 NCBI chr 9:99,005,336...99,025,296
Ensembl chr 9:127,677,841...127,697,880 		JBrowse link
lactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4GALT4 beta-1,4-galactosyltransferase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:116,329,595...116,358,779
Ensembl chr 3:123,241,676...123,270,806 		JBrowse link
G B4GALT6 beta-1,4-galactosyltransferase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:24,840,106...24,906,309
Ensembl chr18:28,438,302...28,500,946 		JBrowse link
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431) MGI
Ensembl		 PMID:25691431 GO_REF:0000107 NCBI chr2B:77,076,432...77,090,531
Ensembl chr2B:194,996,437...195,009,102 		JBrowse link
G ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431) MGI
Ensembl		 PMID:25691431 GO_REF:0000107 NCBI chr12:33,091,020...33,093,794
Ensembl chr12:33,815,514...33,818,669 		JBrowse link
G ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431) MGI
Ensembl		 PMID:25691431 GO_REF:0000107 NCBI chr17:17,361,624...17,368,194
Ensembl chr17:17,581,612...17,587,741 		JBrowse link
G SPHK1 sphingosine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:70,331,370...70,336,043
Ensembl chr17:75,883,329...75,886,481 		JBrowse link
omega-hydroxyceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PNPLA1 patatin like phospholipase domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:35,828,778...35,872,129
Ensembl chr 6:37,002,466...37,067,190 		JBrowse link
positive regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCN1 cellular communication network factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19364818) Ensembl
MGI		 PMID:19364818 GO_REF:0000107 NCBI chr 1:118,138,739...118,141,681
Ensembl chr 1:86,994,296...86,997,147 		JBrowse link
G ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISO (MGI:4947032|PMID:21177474) UniProt PMID:21177474 MGI:4947032 NCBI chr17:73,811,249...73,822,719
Ensembl chr17:79,347,505...79,359,349 		JBrowse link
G PLA2G6 phospholipase A2 group VI involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:18936091 GO_REF:0000118 RGD:6482750 NCBI chr22:18,998,060...19,094,507
Ensembl chr22:36,849,794...36,919,509
Ensembl chr22:36,849,794...36,919,509 		JBrowse link
G PRKCD protein kinase C delta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:53,104,137...53,135,588
Ensembl chr 3:54,330,328...54,357,910 		JBrowse link
G SIRT3 sirtuin 3 involved_in ISO (MGI:5755322|PMID:26620563) UniProt PMID:26620563 MGI:5755322 NCBI chr11:210,052...233,969
Ensembl chr11:255,191...278,732 		JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 ISO RGD PMID:20096352 RGD:10041064 NCBI chr16:48,734,664...48,825,241
Ensembl chr16:68,131,905...68,142,871 		JBrowse link
G SPHK2 sphingosine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:45,620,980...45,631,786
Ensembl chr19:54,213,166...54,224,767 		JBrowse link
G ZNF750 zinc finger protein 750 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:37115925) Ensembl
MGI		 PMID:37115925 GO_REF:0000107 NCBI chr17:77,246,953...77,260,598
Ensembl chr17:83,043,886...83,054,446 		JBrowse link
positive regulation of glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKCD protein kinase C delta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:53,104,137...53,135,588
Ensembl chr 3:54,330,328...54,357,910 		JBrowse link
regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:31880535) UniProt
MGI
Ensembl		 PMID:31880535 GO_REF:0000104 GO_REF:0000107 GO_REF:0000117 NCBI chr2B:77,076,432...77,090,531
Ensembl chr2B:194,996,437...195,009,102 		JBrowse link
G ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 involved_in IEA UniProt GO_REF:0000104 GO_REF:0000117 NCBI chr12:33,091,020...33,093,794
Ensembl chr12:33,815,514...33,818,669 		JBrowse link
G ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:31880535) Ensembl
MGI
UniProt		 PMID:31880535 GO_REF:0000104 GO_REF:0000107 GO_REF:0000117 NCBI chr17:17,361,624...17,368,194
Ensembl chr17:17,581,612...17,587,741 		JBrowse link
G PAQR4 progestin and adipoQ receptor family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:1,911,141...1,915,334
Ensembl chr16:3,083,173...3,087,411 		JBrowse link
G PRKCD protein kinase C delta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:53,104,137...53,135,588
Ensembl chr 3:54,330,328...54,357,910 		JBrowse link
G SAMD8 sterile alpha motif domain containing 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:71,640,271...71,710,674
Ensembl chr10:74,304,676...74,369,601 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16768
    metabolic process 11045
      amide metabolic process 413
        ceramide metabolic process 105
          ceramide biosynthetic process + 68
          ceramide catabolic process + 22
          ganglioside metabolic process + 28
          glycosylceramide metabolic process + 17
          lactosylceramide metabolic process + 2
Path 2
Term Annotations click to browse term
  biological_process 16768
    metabolic process 11045
      primary metabolic process 9771
        lipid metabolic process 1303
          cellular lipid metabolic process 973
            membrane lipid metabolic process 198
              sphingolipid metabolic process 146
                ceramide metabolic process 105
                  ceramide biosynthetic process + 68
                  ceramide catabolic process + 22
                  ganglioside metabolic process + 28
                  glycosylceramide metabolic process + 17
                  lactosylceramide metabolic process + 2
paths to the root