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ONTOLOGY REPORT - ANNOTATIONS


Term:platelet activating factor biosynthetic process
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Accession:GO:0006663 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli.
Synonyms:exact_synonym: PAF biosynthesis;   PAF biosynthetic process;   platelet activating factor anabolism;   platelet activating factor biosynthesis;   platelet activating factor formation;   platelet activating factor synthesis



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platelet activating factor biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chpt1 choline phosphotransferase 1 involved_in ISO
IEA
(PMID:10893425)
GO_REF:0000107
RGD
Ensembl
PMID:10893425 GO_REF:0000107 NCBI chr 7:22,866,455...22,915,111
Ensembl chr 7:22,863,027...22,915,103
JBrowse link
G Lpcat2 lysophosphatidylcholine acyltransferase 2 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:17182612)
UniProt
Ensembl
RGD
PMID:17182612 GO_REF:0000024 GO_REF:0000107 NCBI chr19:14,088,389...14,152,742
Ensembl chr19:14,089,686...14,152,829
JBrowse link
G Pla2g4a phospholipase A2 group 4A involved_in IEA
ISO
GO_REF:0000107
(PMID:9403692)
Ensembl
RGD
PMID:9403692 GO_REF:0000107 NCBI chr13:64,427,921...64,572,352
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Pla2g4c phospholipase A2 group IVC involved_in ISO (PMID:19501189) RGD PMID:19501189 NCBI chr 1:83,315,017...83,411,342
Ensembl chr 1:74,236,211...74,274,656
JBrowse link
G Pla2g5 phospholipase A2, group V IDA RGD PMID:11106649 RGD:2303037 NCBI chr 5:156,324,628...156,393,065
Ensembl chr 5:151,041,340...151,062,658
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20553
    cellular process 19543
      metabolic process 12181
        biosynthetic process 8648
          lipid biosynthetic process 731
            ether lipid biosynthetic process 13
              platelet activating factor biosynthetic process 5
Path 2
Term Annotations click to browse term
  biological_process 20553
    cellular process 19543
      metabolic process 12181
        primary metabolic process 10757
          lipid metabolic process 1464
            lipid biosynthetic process 731
              glycerolipid biosynthetic process 210
                glycerophospholipid biosynthetic process 162
                  platelet activating factor biosynthetic process 5
paths to the root