Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:platelet activating factor biosynthetic process
go back to main search page
Accession:GO:0006663 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli.
Synonyms:exact_synonym: PAF biosynthesis;   PAF biosynthetic process;   platelet activating factor anabolism;   platelet activating factor biosynthesis;   platelet activating factor formation;   platelet activating factor synthesis


show annotations for term's descendants           Sort by:
 
platelet activating factor biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chpt1 choline phosphotransferase 1 ISO (PMID:10893425) RGD PMID:10893425 NCBI chr 7:29,019,518...29,070,928
Ensembl chr 7:29,043,916...29,070,928
JBrowse link
G Lpcat2 lysophosphatidylcholine acyltransferase 2 IEA
ISO
ISS
GO_REF:0000107
(MGI:MGI:3708195|PMID:17182612)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:17182612 GO_REF:0000024, GO_REF:0000107, MGI:MGI:3708195 NCBI chr19:15,470,177...15,540,704
Ensembl chr19:15,469,303...15,540,773
JBrowse link
G Pla2g4a phospholipase A2 group IVA IEA
ISO
GO_REF:0000107
(MGI:MGI:1100762|PMID:9403692)
Ensembl
RGD
PMID:9403692 GO_REF:0000107, MGI:MGI:1100762 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Pla2g4c phospholipase A2 group IVC ISO (PMID:19501189) RGD PMID:19501189 NCBI chr 1:75,440,035...75,481,995
Ensembl chr 1:75,428,027...75,620,911
JBrowse link
G Pla2g5 phospholipase A2, group V IDA RGD PMID:11106649 RGD:2303037 NCBI chr 5:157,247,601...157,268,968
Ensembl chr 5:157,247,781...157,268,903
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      organic substance metabolic process 11660
        organonitrogen compound metabolic process 7186
          platelet activating factor metabolic process 8
            platelet activating factor biosynthetic process 5
Path 2
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      cellular metabolic process 11085
        phosphorus metabolic process 3301
          phosphate-containing compound metabolic process 3280
            phospholipid metabolic process 381
              glycerophospholipid metabolic process 293
                platelet activating factor metabolic process 8
                  platelet activating factor biosynthetic process 5
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.