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Term:platelet activating factor biosynthetic process
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Accession:GO:0006663 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli.
Synonyms:exact_synonym: PAF biosynthesis;   PAF biosynthetic process;   platelet activating factor anabolism;   platelet activating factor biosynthesis;   platelet activating factor formation;   platelet activating factor synthesis

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platelet activating factor biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chpt1 choline phosphotransferase 1 involved_in ISO (PMID:10893425) RGD PMID:10893425 NCBI chr 7:22,866,455...22,915,111
Ensembl chr 7:22,863,027...22,915,103
JBrowse link
G Lpcat2 lysophosphatidylcholine acyltransferase 2 involved_in ISS
PMID:17182612 GO_REF:0000024 GO_REF:0000107 MGI:3708195 NCBI chr19:14,088,389...14,152,742
Ensembl chr19:14,089,686...14,152,829
JBrowse link
G Pla2g4a phospholipase A2 group IVA involved_in ISO (MGI:1100762|PMID:9403692) RGD PMID:9403692 MGI:1100762 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Pla2g4c phospholipase A2 group IVC involved_in ISO (PMID:19501189) RGD PMID:19501189 NCBI chr 1:74,249,688...74,272,133
Ensembl chr 1:74,236,211...74,274,656
JBrowse link
G Pla2g5 phospholipase A2, group V IDA RGD PMID:11106649 RGD:2303037 NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19898
    metabolic process 12211
      biosynthetic process 6289
        organic substance biosynthetic process 6196
          organonitrogen compound biosynthetic process 2178
            platelet activating factor biosynthetic process 5
Path 2
Term Annotations click to browse term
  biological_process 19898
    metabolic process 12211
      cellular metabolic process 9631
        phosphorus metabolic process 2886
          phosphate-containing compound metabolic process 2858
            phospholipid metabolic process 382
              glycerophospholipid metabolic process 288
                platelet activating factor metabolic process 8
                  platelet activating factor biosynthetic process 5
paths to the root