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ONTOLOGY REPORT - ANNOTATIONS

Term:phosphatidylinositol biosynthetic process
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Accession:GO:0006661 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of phosphatidylinositol, any glycophospholipid in which the sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
Synonyms:exact_synonym: PtdIns biosynthesis;   PtdIns biosynthetic process;   phosphatidylinositol anabolism;   phosphatidylinositol biosynthesis;   phosphatidylinositol formation;   phosphatidylinositol synthesis;   phosphoinositide biosynthesis;   phosphoinositide biosynthetic process
 alt_id: GO:0046489


show annotations for term's descendants           Sort by:
phosphatidylinositol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase involved_in IDA
IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:8110188), (PMID:9407135)		 GO_Central
Ensembl
RGD		 PMID:8110188 PMID:9407135 PMID:8804431 PMID:7998949 GO_REF:0000033 GO_REF:0000107, RGD:724663, RGD:1626301 NCBI chr 1:181,583,098...181,587,409
Ensembl chr 1:181,583,141...181,587,408 		JBrowse link
G Cds1 CDP-diacylglycerol synthase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:9407135)		 UniProt
RGD		 PMID:9407135 GO_REF:0000024 NCBI chr14:7,820,328...7,882,943
Ensembl chr14:7,820,351...7,882,681 		JBrowse link
G Dgke diacylglycerol kinase epsilon involved_in ISO (MGI:6414743|PMID:19744926) RGD PMID:19744926 MGI:6414743 NCBI chr10:73,853,030...73,877,334
Ensembl chr10:73,855,583...73,877,100 		JBrowse link
G Impa1 inositol monophosphatase 1 involved_in IMP
ISO		 (PMID:1377913) RGD PMID:1377913 PMID:11853098 RGD:2302239 NCBI chr 2:91,462,781...91,484,057
Ensembl chr 2:91,462,799...91,484,313 		JBrowse link
G Inppl1 inositol polyphosphate phosphatase-like 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:21624956)		 Ensembl
RGD		 PMID:21624956 GO_REF:0000107 NCBI chr 1:156,183,043...156,197,500
Ensembl chr 1:156,183,059...156,197,500 		JBrowse link
G Mboat7 membrane bound O-acyltransferase domain containing 7 involved_in ISO (PMID:18094042) RGD PMID:18094042 NCBI chr 1:65,525,206...65,539,538
Ensembl chr 1:65,525,213...65,539,538 		JBrowse link
G Pi4k2a phosphatidylinositol 4-kinase type 2 alpha involved_in ISO
ISS		 (PMID:11279162)
GO_REF:0000024		 RGD
UniProt		 PMID:11279162 GO_REF:0000024 NCBI chr 1:240,902,804...240,929,234
Ensembl chr 1:240,902,855...240,929,337 		JBrowse link
G Pip4k2c phosphatidylinositol-5-phosphate 4-kinase type 2 gamma NAS RGD PMID:9685379 RGD:633581 NCBI chr 7:63,020,004...63,035,086
Ensembl chr 7:63,020,000...63,035,078 		JBrowse link
G Pip5k1a phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha acts_upstream_of_or_within ISO MGI:1298224 (PMID:20622009) RGD PMID:20622009 NCBI chr 2:182,628,299...182,671,584
Ensembl chr 2:182,628,300...182,671,598 		JBrowse link
G Pip5k1b phosphatidylinositol-4-phosphate 5-kinase type 1 beta acts_upstream_of_or_within ISO MGI:1298224 (PMID:20622009) RGD PMID:20622009 NCBI chr 1:221,907,220...222,183,672
Ensembl chr 1:221,914,159...222,183,672 		JBrowse link
G Pip5k1c phosphatidylinositol-4-phosphate 5-kinase type 1 gamma acts_upstream_of_or_within ISO MGI:3054978 (PMID:20622009) RGD PMID:20622009 NCBI chr 7:8,397,406...8,426,030
Ensembl chr 7:8,397,406...8,425,988 		JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:11606584), (PMID:12181444)		 Ensembl
UniProt
RGD		 PMID:11606584 PMID:12181444 GO_REF:0000024 GO_REF:0000107 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Sh3yl1 SH3 and SYLF domain containing 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:21624956)		 Ensembl
RGD		 PMID:21624956 GO_REF:0000107 NCBI chr 6:47,522,098...47,565,858
Ensembl chr 6:47,522,091...47,565,858 		JBrowse link
G Slc27a1 solute carrier family 27 member 1 involved_in ISO
IEA		 (PMID:19523918)
GO_REF:0000118
GO_REF:0000107		 RGD
TreeGrafter
Ensembl		 PMID:19523918 GO_REF:0000107 GO_REF:0000118 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063 		JBrowse link
G Vac14 VAC14 component of PIKFYVE complex involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:38,590,569...38,691,911
Ensembl chr19:38,590,569...38,691,909 		JBrowse link
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase type 2 alpha involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:26774281)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:26774281 GO_REF:0000024 GO_REF:0000107 NCBI chr17:81,496,669...81,668,180
Ensembl chr17:81,496,670...81,668,029 		JBrowse link
G Pip4k2b phosphatidylinositol-5-phosphate 4-kinase type 2 beta involved_in ISO
ISS
IEA		 (PMID:26774281)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:26774281 GO_REF:0000024 GO_REF:0000107 NCBI chr10:82,706,016...82,734,938
Ensembl chr10:82,701,098...82,734,938 		JBrowse link
G Pip4k2c phosphatidylinositol-5-phosphate 4-kinase type 2 gamma involved_in ISO
ISS
IEA		 (PMID:26774281)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:26774281 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:63,020,004...63,035,086
Ensembl chr 7:63,020,000...63,035,078 		JBrowse link
attachment of GPI anchor to protein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpaa1 glycosylphosphatidylinositol anchor attachment 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:108,051,896...108,055,479
Ensembl chr 7:108,051,861...108,055,484 		JBrowse link
G Pigk phosphatidylinositol glycan anchor biosynthesis, class K involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:241,630,021...241,715,493
Ensembl chr 2:241,630,053...241,716,134 		JBrowse link
G Pigs phosphatidylinositol glycan anchor biosynthesis, class S involved_in ISO
IBA		 (MGI:3688056|PMID:11483512)
GO_REF:0000033		 RGD
GO_Central		 PMID:11483512 GO_REF:0000033 MGI:3688056 NCBI chr10:63,222,611...63,237,190
Ensembl chr10:63,222,572...63,237,187 		JBrowse link
G Pigt phosphatidylinositol glycan anchor biosynthesis, class T involved_in ISO
IBA		 (MGI:3688056|PMID:11483512)
GO_REF:0000033		 RGD
GO_Central		 PMID:11483512 GO_REF:0000033 MGI:3688056 NCBI chr 3:153,227,749...153,236,922
Ensembl chr 3:153,227,420...153,236,887 		JBrowse link
G Pigu phosphatidylinositol glycan anchor biosynthesis, class U involved_in IEA
IBA
ISO		 GO_REF:0000002
GO_REF:0000118
GO_REF:0000033
GO_REF:0000107
(PMID:12802054)		 InterPro
TreeGrafter
GO_Central
Ensembl
RGD		 PMID:12802054 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:143,784,831...143,881,268
Ensembl chr 3:143,784,832...143,880,807 		JBrowse link
GPI anchor biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07038703.1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr  X:54,564,018...54,565,271 JBrowse link
G Cwh43 cell wall biogenesis 43 C-terminal homolog involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:34,754,279...34,800,530
Ensembl chr14:34,754,289...34,800,814 		JBrowse link
G Dpm1 dolichyl-phosphate mannosyltransferase subunit 1, catalytic involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:10835346), (PMID:9535917)
(PMID:9535917)
GO_REF:0000033
(PMID:9535917), (PMID:9724629)		 RGD
GO_Central		 PMID:9535917 PMID:9724629 PMID:10835346 GO_REF:0000033 NCBI chr 3:156,919,979...156,939,522
Ensembl chr 3:156,919,979...156,939,536 		JBrowse link
G Dpm2 dolichyl-phosphate mannosyltransferase subunit 2, regulatory acts_upstream_of_or_within
involved_in		 TAS
IDA
ISO
IEA
IBA		 PMID:9724629
(PMID:10835346), (PMID:16162815)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:10835346 PMID:16162815 PMID:9724629 PMID:9724629 GO_REF:0000033 GO_REF:0000107, RGD:69827, RGD:69827 NCBI chr 3:15,855,952...15,858,867
Ensembl chr 3:15,856,182...15,869,165
Ensembl chr 3:15,856,182...15,869,165 		JBrowse link
G Dpm3 dolichyl-phosphate mannosyltransferase subunit 3, regulatory involved_in ISO
IBA		 (PMID:10835346)
GO_REF:0000033		 RGD
GO_Central		 PMID:10835346 GO_REF:0000033 NCBI chr 2:174,676,532...174,677,047
Ensembl chr 2:174,676,363...174,677,668
Ensembl chr15:174,676,363...174,677,668 		JBrowse link
G Gpaa1 glycosylphosphatidylinositol anchor attachment 1 TAS RGD PMID:10702226 RGD:1331364 NCBI chr 7:108,051,896...108,055,479
Ensembl chr 7:108,051,861...108,055,484 		JBrowse link
G Mppe1 metallophosphoesterase 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000043
(PMID:29374258)		 UniProt
RGD		 PMID:29374258 GO_REF:0000024 GO_REF:0000043 NCBI chr18:60,763,418...60,781,553
Ensembl chr18:60,763,419...60,781,553 		JBrowse link
G Pgap1 post-GPI attachment to proteins inositol deacylase 1 IMP RGD PMID:14734546 RGD:1303970 NCBI chr 9:55,975,574...56,044,325
Ensembl chr 9:55,975,667...56,044,464 		JBrowse link
G Pgap2 post-GPI attachment to proteins 2 involved_in IMP
IEA
IBA
ISO		 PMID:16407401
GO_REF:0000118
GO_REF:0000033
GO_REF:0000043
(PMID:29374258)		 TreeGrafter
GO_Central
UniProt
RGD		 PMID:29374258 PMID:16407401 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118, RGD:8553507 NCBI chr 1:156,591,540...156,618,116
Ensembl chr 1:156,591,615...156,618,114 		JBrowse link
G Pgap3 post-GPI attachment to proteins phospholipase 3 involved_in ISO
IBA		 (PMID:29374258)
GO_REF:0000033		 RGD
GO_Central		 PMID:29374258 GO_REF:0000033 NCBI chr10:83,387,113...83,399,357
Ensembl chr10:83,387,113...83,398,628 		JBrowse link
G Pgap4 post-GPI attachment to proteins GalNAc transferase 4 involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:29374258)		 UniProt
GO_Central
RGD		 PMID:29374258 GO_REF:0000024 GO_REF:0000033 NCBI chr 5:63,931,916...63,947,004
Ensembl chr 5:63,930,682...63,951,716 		JBrowse link
G Piga phosphatidylinositol glycan anchor biosynthesis, class A involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000041
MGI:3652879 (PMID:8611683)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:8611683 GO_REF:0000033 GO_REF:0000041 NCBI chr  X:30,043,033...30,055,861
Ensembl chr  X:30,042,343...30,055,804 		JBrowse link
G Pigb phosphatidylinositol glycan anchor biosynthesis, class B involved_in ISO
IBA		 (PMID:8861954)
GO_REF:0000033		 RGD
GO_Central		 PMID:8861954 GO_REF:0000033 NCBI chr 8:73,751,756...73,775,679
Ensembl chr 8:73,751,798...73,775,679 		JBrowse link
G Pigc phosphatidylinositol glycan anchor biosynthesis, class C involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000041
(PMID:16162815), (PMID:27694521)		 UniProt
RGD		 PMID:16162815 PMID:27694521 GO_REF:0000024 GO_REF:0000041 NCBI chr13:74,343,619...74,346,148
Ensembl chr13:74,296,854...74,346,211 		JBrowse link
G Pigf phosphatidylinositol glycan anchor biosynthesis, class F involved_in ISO
IBA
IEA		 (PMID:33386993)
GO_REF:0000033
GO_REF:0000041
(MGI:1860649|PMID:10781593)		 RGD
GO_Central
UniProt		 PMID:10781593 PMID:33386993 GO_REF:0000033 GO_REF:0000041 MGI:1860649 NCBI chr 6:7,589,584...7,617,719
Ensembl chr 6:7,589,570...7,639,675 		JBrowse link
G Pigg phosphatidylinositol glycan anchor biosynthesis, class G acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15632136)
GO_REF:0000041		 RGD
UniProt		 PMID:15632136 GO_REF:0000041 NCBI chr14:1,404,911...1,433,199
Ensembl chr14:1,406,798...1,433,187 		JBrowse link
G Pigh phosphatidylinositol glycan anchor biosynthesis, class H involved_in ISO
IBA
IEA		 (PMID:16162815)
GO_REF:0000033
GO_REF:0000041		 RGD
GO_Central
UniProt		 PMID:16162815 GO_REF:0000033 GO_REF:0000041 NCBI chr 6:97,874,903...97,897,188
Ensembl chr 6:97,882,903...97,897,142 		JBrowse link
G Pigl phosphatidylinositol glycan anchor biosynthesis, class L IDA RGD PMID:9188481 RGD:729509 NCBI chr10:47,142,160...47,199,892
Ensembl chr10:47,141,780...47,200,145 		JBrowse link
G Pigm phosphatidylinositol glycan anchor biosynthesis, class M involved_in IDA
IBA
IEA		 GO_REF:0000033
GO_REF:0000041		 GO_Central
UniProt
RGD		 PMID:11226175 GO_REF:0000033 GO_REF:0000041, RGD:70624 NCBI chr13:84,838,329...84,842,026
Ensembl chr13:84,838,175...84,843,381 		JBrowse link
G Pign phosphatidylinositol glycan anchor biosynthesis, class N involved_in IEA
IBA		 GO_REF:0000041
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000041 NCBI chr13:21,659,092...21,812,932
Ensembl chr13:21,662,455...21,806,790 		JBrowse link
G Pigo phosphatidylinositol glycan anchor biosynthesis, class O involved_in ISO
IBA
IEA		 (MGI:1860649|PMID:10781593)
GO_REF:0000033
GO_REF:0000041		 RGD
GO_Central
UniProt		 PMID:10781593 GO_REF:0000033 GO_REF:0000041 MGI:1860649 NCBI chr 5:57,244,721...57,256,252
Ensembl chr 5:57,245,166...57,254,146 		JBrowse link
G Pigp phosphatidylinositol glycan anchor biosynthesis, class P involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:16162815), (PMID:28334793)
(PMID:10944123)
GO_REF:0000033		 RGD
GO_Central		 PMID:10944123 PMID:16162815 PMID:28334793 GO_REF:0000033 NCBI chr11:33,682,943...33,689,111
Ensembl chr11:33,682,948...33,689,321 		JBrowse link
G Pigq phosphatidylinositol glycan anchor biosynthesis, class Q involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:16162815)
PomBase:SPBC30D10.11|SGD:S000003448 (PMID:10373468), (PMID:9729469)
GO_REF:0000033		 RGD
GO_Central		 PMID:9729469 PMID:10373468 PMID:16162815 GO_REF:0000033 NCBI chr10:14,942,571...14,958,584
Ensembl chr10:14,942,577...14,958,584 		JBrowse link
G Pigu phosphatidylinositol glycan anchor biosynthesis, class U involved_in ISO (PMID:15034568) RGD PMID:15034568 NCBI chr 3:143,784,831...143,881,268
Ensembl chr 3:143,784,832...143,880,807 		JBrowse link
G Pigv phosphatidylinositol glycan anchor biosynthesis, class V involved_in ISO
IBA
IEA		 UniProtKB:P38211 (PMID:15623507), (PMID:15720390)
GO_REF:0000033
GO_REF:0000041		 RGD
GO_Central
UniProt		 PMID:15623507 PMID:15720390 GO_REF:0000033 GO_REF:0000041 NCBI chr 5:145,889,642...145,901,533
Ensembl chr 5:145,889,646...145,901,533 		JBrowse link
G Pigw phosphatidylinositol glycan anchor biosynthesis, class W involved_in IEA
IBA		 GO_REF:0000041
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000041 NCBI chr10:69,746,996...69,782,656
Ensembl chr10:69,748,789...69,790,475 		JBrowse link
G Pigx phosphatidylinositol glycan anchor biosynthesis, class X involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr11:68,687,126...68,703,067
Ensembl chr11:68,687,093...68,703,472 		JBrowse link
G Pigy phosphatidylinositol glycan anchor biosynthesis, class Y acts_upstream_of_or_within ISO (PMID:16162815) RGD PMID:16162815 NCBI chr 8:20,689,621...20,691,863
Ensembl chr 8:20,689,502...20,692,585 		JBrowse link
G Pigz phosphatidylinositol glycan anchor biosynthesis, class Z involved_in ISO UniProtKB:Q04174 (PMID:15208306) RGD PMID:15208306 NCBI chr11:68,831,847...68,851,798 JBrowse link
G Slc30a5 solute carrier family 30 member 5 acts_upstream_of_positive_effect ISO (PMID:35525268) RGD PMID:35525268 NCBI chr 2:31,945,745...31,975,969
Ensembl chr 2:31,945,729...31,975,934 		JBrowse link
negative regulation of phosphatidylinositol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfa platelet derived growth factor subunit A involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:2538439)		 UniProt
Ensembl
RGD		 PMID:2538439 GO_REF:0000024 GO_REF:0000107 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:2538439)		 UniProt
Ensembl
RGD		 PMID:2538439 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
phosphatidylinositol phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bpnt1 3'(2'), 5'-bisphosphate nucleotidase 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:96,865,634...96,893,506
Ensembl chr13:96,868,580...96,893,503 		JBrowse link
G Bpnt2 3'(2'), 5'-bisphosphate nucleotidase 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:17,775,684...17,802,570
Ensembl chr 5:17,772,608...17,802,570 		JBrowse link
G Cish cytokine inducible SH2-containing protein involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000118		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250 		JBrowse link
G Efr3b EFR3 homolog B involved_in ISO (PMID:23229899) RGD PMID:23229899 NCBI chr 6:26,947,436...27,021,113
Ensembl chr 6:26,948,540...27,020,933 		JBrowse link
G Hycc1 hyccin PI4KA lipid kinase complex subunit 1 involved_in ISO
IBA		 (PMID:26571211)
GO_REF:0000033		 RGD
GO_Central		 PMID:26571211 GO_REF:0000033 NCBI chr 4:11,132,224...11,239,120
Ensembl chr 4:11,132,385...11,239,113 		JBrowse link
G Hycc2 hyccin PI4KA lipid kinase complex subunit 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:60,056,883...60,129,176
Ensembl chr 9:60,056,890...60,093,007 		JBrowse link
G Impa1 inositol monophosphatase 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:91,462,781...91,484,057
Ensembl chr 2:91,462,799...91,484,313 		JBrowse link
G Impa2 inositol monophosphatase 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr18:60,834,206...60,867,575
Ensembl chr18:60,834,246...60,865,641 		JBrowse link
G Inpp1 inositol polyphosphate-1-phosphatase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:48,688,037...48,717,793
Ensembl chr 9:48,669,901...48,717,793 		JBrowse link
G Ip6k1 inositol hexakisphosphate kinase 1 involved_in ISS
ISO
IBA		 GO_REF:0000024
(PMID:10574768)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:10574768 GO_REF:0000024 GO_REF:0000033 NCBI chr 8:108,693,068...108,737,278 JBrowse link
G Ip6k2 inositol hexakisphosphate kinase 2 involved_in ISO
IEA
IBA		 (PMID:10574768)
GO_REF:0000107
GO_REF:0000118
GO_REF:0000033		 RGD
Ensembl
TreeGrafter
GO_Central		 PMID:10574768 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:109,483,843...109,510,172
Ensembl chr 8:109,484,310...109,510,166 		JBrowse link
G Ip6k3 inositol hexakisphosphate kinase 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:5,223,863...5,245,443
Ensembl chr20:5,224,120...5,245,428 		JBrowse link
G Itpka inositol-trisphosphate 3-kinase A involved_in ISS
ISO		 GO_REF:0000024
(PMID:12747803), (PMID:1847047)		 UniProt
RGD		 PMID:1847047 PMID:12747803 GO_REF:0000024 NCBI chr 3:106,726,036...106,734,601
Ensembl chr 3:106,726,036...106,734,600 		JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B involved_in ISS
ISO		 GO_REF:0000024
(PMID:12747803)		 UniProt
RGD		 PMID:12747803 GO_REF:0000024 NCBI chr13:92,069,160...92,164,281
Ensembl chr13:92,069,216...92,162,004 		JBrowse link
G Itpkc inositol-trisphosphate 3-kinase C involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:11085927), (PMID:12747803)		 UniProt
Ensembl
RGD		 PMID:11085927 PMID:12747803 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:82,500,957...82,522,533
Ensembl chr 1:82,500,957...82,522,779 		JBrowse link
G P3r3urf PIK3R3 upstream open reading frame involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:129,656,654...129,673,140
Ensembl chr 5:129,656,833...129,672,848 		JBrowse link
G Pi4k2a phosphatidylinositol 4-kinase type 2 alpha involved_in ISO
IEA
IBA		 (PMID:11923287), (PMID:12324459), (PMID:25168678)
GO_REF:0000104
GO_REF:0000033		 RGD
UniProt
GO_Central		 PMID:11923287 PMID:12324459 PMID:25168678 GO_REF:0000033 GO_REF:0000104 NCBI chr 1:240,902,804...240,929,234
Ensembl chr 1:240,902,855...240,929,337 		JBrowse link
G Pi4k2b phosphatidylinositol 4-kinase type 2 beta involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:11923287), (PMID:12324459)		 UniProt
GO_Central
RGD		 PMID:11923287 PMID:12324459 GO_REF:0000024 GO_REF:0000033 NCBI chr14:58,221,790...58,248,716
Ensembl chr14:58,220,437...58,248,673 		JBrowse link
G Pi4ka phosphatidylinositol 4-kinase alpha involved_in ISO
IEA
IBA		 (MGI:5476893|PMID:23229899)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:23229899 GO_REF:0000033 GO_REF:0000107 MGI:5476893 NCBI chr11:83,609,148...83,726,876
Ensembl chr11:83,609,069...83,724,080 		JBrowse link
G Pi4kb phosphatidylinositol 4-kinase beta involved_in IEA
IBA		 GO_REF:0000002
GO_REF:0000118
GO_REF:0000033		 InterPro
TreeGrafter
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:182,540,377...182,572,684
Ensembl chr 2:182,540,567...182,588,488 		JBrowse link
G Pik3c2g phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:172,483,752...172,851,623
Ensembl chr 4:172,484,345...172,850,544 		JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 involved_in ISO (PMID:7628435) RGD PMID:7628435 NCBI chr18:21,845,282...21,934,387
Ensembl chr18:21,845,295...21,929,048 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha IDA RGD PMID:12882977 RGD:4144086 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta involved_in IDA
ISO		 (PMID:12502714) RGD PMID:12502714 PMID:12882977 RGD:4144086 NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma involved_in IDA
ISO		 (PMID:12502714) RGD PMID:12502714 PMID:12882977 RGD:4144086 NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in ISS
IEA
IBA		 GO_REF:0000024
GO_REF:0000118
GO_REF:0000033		 UniProt
TreeGrafter
GO_Central		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000118		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr16:18,665,517...18,674,067
Ensembl chr16:18,665,457...18,674,065 		JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000118		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583 		JBrowse link
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase type 2 alpha involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:81,496,669...81,668,180
Ensembl chr17:81,496,670...81,668,029 		JBrowse link
G Pip4k2b phosphatidylinositol-5-phosphate 4-kinase type 2 beta involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:82,706,016...82,734,938
Ensembl chr10:82,701,098...82,734,938 		JBrowse link
G Pip4k2c phosphatidylinositol-5-phosphate 4-kinase type 2 gamma involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000118		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:63,020,004...63,035,086
Ensembl chr 7:63,020,000...63,035,078 		JBrowse link
G Pip5k1a phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000118		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:182,628,299...182,671,584
Ensembl chr 2:182,628,300...182,671,598 		JBrowse link
G Pip5k1b phosphatidylinositol-4-phosphate 5-kinase type 1 beta involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000118		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:221,907,220...222,183,672
Ensembl chr 1:221,914,159...222,183,672 		JBrowse link
G Pip5k1c phosphatidylinositol-4-phosphate 5-kinase type 1 gamma involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:8,397,406...8,426,030
Ensembl chr 7:8,397,406...8,425,988 		JBrowse link
G Pip5kl1 phosphatidylinositol-4-phosphate 5-kinase-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:15,860,493...15,869,264
Ensembl chr 3:15,855,946...15,869,165 		JBrowse link
G Sla2 Src-like-adaptor 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:145,367,070...145,383,586
Ensembl chr 3:145,368,598...145,382,480 		JBrowse link
G Smg1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase involved_in ISO (PMID:11331269) RGD PMID:11331269 NCBI chr 1:172,441,892...172,543,667
Ensembl chr 1:172,444,936...172,543,698 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000118		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383 		JBrowse link
G Socs2 suppressor of cytokine signaling 2 involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787 		JBrowse link
G Socs4 suppressor of cytokine signaling 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:20,523,406...20,537,889
Ensembl chr15:20,523,183...20,542,494 		JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:7,481,039...7,512,644
Ensembl chr 6:7,481,095...7,514,834 		JBrowse link
G Socs6 suppressor of cytokine signaling 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:82,111,866...82,139,193
Ensembl chr18:82,111,827...82,139,219 		JBrowse link
G Socs7 suppressor of cytokine signaling 7 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:82,352,159...82,388,829
Ensembl chr10:82,351,680...82,388,830 		JBrowse link
G Tmem150a transmembrane protein 150A involved_in ISS
ISO		 GO_REF:0000024
(PMID:25608530)		 UniProt
RGD		 PMID:25608530 GO_REF:0000024 NCBI chr 4:104,410,271...104,414,630
Ensembl chr 4:104,410,516...104,429,349 		JBrowse link
G Ttc7a tetratricopeptide repeat domain 7A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:7,159,285...7,261,826
Ensembl chr 6:7,159,061...7,261,892 		JBrowse link
G Ttc7b tetratricopeptide repeat domain 7B involved_in ISO
IBA		 (PMID:23229899), (PMID:26571211)
GO_REF:0000033		 RGD
GO_Central		 PMID:23229899 PMID:26571211 GO_REF:0000033 NCBI chr 6:119,587,389...119,799,167
Ensembl chr 6:119,587,390...119,799,330 		JBrowse link
phosphatidylinositol-3-phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg14 autophagy related 14 involved_in ISO (PMID:8999962) RGD PMID:8999962 NCBI chr15:20,795,750...20,827,113
Ensembl chr15:20,795,750...20,827,113 		JBrowse link
G Atm ATM serine/threonine kinase involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Becn1 beclin 1 involved_in ISO (PMID:8999962) RGD PMID:8999962 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Fig4 FIG4 phosphoinositide 5-phosphatase involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr20:44,600,603...44,724,047
Ensembl chr20:44,600,603...44,723,844 		JBrowse link
G Inpp4a inositol polyphosphate-4-phosphatase type I A involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 9:39,528,245...39,650,574
Ensembl chr 9:39,528,674...39,646,581 		JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634 		JBrowse link
G Inpp5e inositol polyphosphate-5-phosphatase E involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:9,216,776...9,229,539
Ensembl chr 3:9,216,776...9,229,450 		JBrowse link
G Pik3c2a phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:2685045 (PMID:24098492)		 GO_Central
RGD		 PMID:24098492 GO_REF:0000033 NCBI chr 1:170,577,942...170,684,353
Ensembl chr 1:170,577,942...170,683,472 		JBrowse link
G Pik3c2b phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1203729 (PMID:24098492)		 GO_Central
RGD		 PMID:24098492 GO_REF:0000033 NCBI chr13:44,494,673...44,555,663
Ensembl chr13:44,495,050...44,555,612 		JBrowse link
G Pik3c2g phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma involved_in ISO
IBA
IDA		 (MGI:1201706|PMID:9514948)
GO_REF:0000033
PMID:9516481		 RGD
GO_Central		 PMID:9514948 PMID:9516481 GO_REF:0000033 MGI:1201706, RGD:729517 NCBI chr 4:172,483,752...172,851,623
Ensembl chr 4:172,484,345...172,850,544 		JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA		 (PMID:8999962)
(PMID:24098492)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000108		 RGD
GO_Central
Ensembl
GOC		 PMID:8999962 PMID:24098492 GO_REF:0000033 GO_REF:0000107 GO_REF:0000108 NCBI chr18:21,845,282...21,934,387
Ensembl chr18:21,845,295...21,929,048 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta involved_in IEA
IBA		 GO_REF:0000108
GO_REF:0000033		 GOC
GO_Central		 GO_REF:0000033 GO_REF:0000108 NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663 		JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:160,094,952...160,142,962
Ensembl chr 5:160,094,952...160,120,930 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Pik3r4 phosphoinositide-3-kinase, regulatory subunit 4 involved_in ISO (PMID:8999962) RGD PMID:8999962 NCBI chr 8:106,267,908...106,316,585
Ensembl chr 8:106,267,954...106,316,584 		JBrowse link
G Uvrag UV radiation resistance associated involved_in ISO (PMID:8999962) RGD PMID:8999962 NCBI chr 1:153,185,356...153,442,200
Ensembl chr 1:153,185,395...153,442,136 		JBrowse link
positive regulation of phosphatidylinositol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr2a 5-hydroxytryptamine receptor 2A involved_in ISO (PMID:19057895) RGD PMID:19057895 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19057895)		 UniProt
Ensembl
RGD		 PMID:19057895 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:86,735,793...86,756,638
Ensembl chr 9:86,742,102...86,755,108 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C involved_in ISO (PMID:19057895) RGD PMID:19057895 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
preassembly of GPI anchor in ER membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pigl phosphatidylinositol glycan anchor biosynthesis, class L involved_in IDA
ISO		 PMID:10085243
(PMID:10085243)		 RGD PMID:10085243 PMID:10085243 RGD:401901217 NCBI chr10:47,142,160...47,199,892
Ensembl chr10:47,141,780...47,200,145 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    metabolic process 11720
      biosynthetic process 8355
        cellular biosynthetic process 8211
          glycerolipid biosynthetic process 226
            glycerophospholipid biosynthetic process 176
              phosphatidylinositol biosynthetic process 106
                GPI anchor biosynthetic process + 33
                negative regulation of phosphatidylinositol biosynthetic process + 2
                phosphatidylinositol phosphate biosynthetic process + 59
                positive regulation of phosphatidylinositol biosynthetic process + 3
                regulation of phosphatidylinositol biosynthetic process + 5
Path 2
Term Annotations click to browse term
  biological_process 20292
    metabolic process 11720
      cellular metabolic process 10279
        phosphorus metabolic process 1934
          phosphate-containing compound metabolic process 1906
            phospholipid metabolic process 385
              glycerophospholipid metabolic process 289
                glycerophospholipid biosynthetic process 176
                  phosphatidylinositol biosynthetic process 106
                    GPI anchor biosynthetic process + 33
                    negative regulation of phosphatidylinositol biosynthetic process + 2
                    phosphatidylinositol phosphate biosynthetic process + 59
                    positive regulation of phosphatidylinositol biosynthetic process + 3
                    regulation of phosphatidylinositol biosynthetic process + 5
paths to the root