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ONTOLOGY REPORT - ANNOTATIONS

Term:triglyceride metabolic process
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Accession:GO:0006641 term browser browse the term
Definition:The chemical reactions and pathways involving triglyceride, any triester of glycerol. The three fatty acid residues may all be the same or differ in any permutation. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins.
Synonyms:exact_synonym: triacylglycerol metabolic process;   triacylglycerol metabolism;   triglyceride metabolism


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triglyceride metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA5 apolipoprotein A5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16166565) Ensembl
MGI		 PMID:16166565 GO_REF:0000107 NCBI chr11:111,625,403...111,627,932
Ensembl chr11:115,559,231...115,562,286 		JBrowse link
G APOBEC1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 acts_upstream_of_or_within ISO (PMID:9240444) MGI PMID:9240444 NCBI chr12:7,777,734...7,793,960
Ensembl chr12:7,939,262...7,944,203 		JBrowse link
G APOC3 apolipoprotein C3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11590213), (PMID:8089130) Ensembl
MGI		 PMID:8089130 PMID:11590213 GO_REF:0000107 NCBI chr11:111,667,816...111,670,861
Ensembl chr11:115,600,416...115,603,460 		JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490 		JBrowse link
G APOF apolipoprotein F acts_upstream_of_or_within ISO (PMID:22363685) MGI PMID:22363685 NCBI chr12:32,552,589...32,554,943
Ensembl chr12:32,806,130...32,807,641 		JBrowse link
G APOH apolipoprotein H involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:60,154,389...60,171,762
Ensembl chr17:65,365,250...65,382,483 		JBrowse link
G CAT catalase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:5087482) Ensembl
MGI		 PMID:5087482 GO_REF:0000107 NCBI chr11:34,413,253...34,446,831
Ensembl chr11:34,289,603...34,323,160 		JBrowse link
G CAV1 caveolin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11884617) Ensembl
MGI		 PMID:11884617 GO_REF:0000107 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655 		JBrowse link
G CAV3 caveolin 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15314230) Ensembl
MGI		 PMID:15314230 GO_REF:0000107 NCBI chr 3:8,684,829...8,697,731
Ensembl chr 3:8,928,069...8,940,942 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) ISO RGD PMID:15331529 RGD:1598387 NCBI chr 7:72,566,478...72,643,517
Ensembl chr 7:86,265,114...86,305,865 		JBrowse link
G CETP cholesteryl ester transfer protein involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr16:37,239,756...37,261,859
Ensembl chr16:56,374,363...56,396,103 		JBrowse link
G CPT1A carnitine palmitoyltransferase 1A ISO RGD PMID:18349115 RGD:2311348 NCBI chr11:63,841,028...63,928,242
Ensembl chr11:67,144,736...67,205,481 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO RGD PMID:20116195 RGD:2317269 Ensembl chr10:134,839,025...134,852,719 JBrowse link
G DBI diazepam binding inhibitor, acyl-CoA binding protein acts_upstream_of_or_within ISO (PMID:16902415) MGI PMID:16902415 NCBI chr2B:6,309,048...6,314,660
Ensembl chr2B:119,887,728...119,892,986 		JBrowse link
G G6PC1 glucose-6-phosphatase catalytic subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10625614), (PMID:8640227) Ensembl
MGI		 PMID:8640227 PMID:10625614 GO_REF:0000107 NCBI chr17:14,407,355...14,419,660
Ensembl chr17:14,635,667...14,646,674 		JBrowse link
G GK glycerol kinase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:23,250,290...23,327,373
Ensembl chr  X:30,806,950...30,877,131 		JBrowse link
G GK2 glycerol kinase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:44,780,488...44,784,433
Ensembl chr 4:50,628,938...50,630,599 		JBrowse link
G GK3 glycerol kinase 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:157,472,574...157,474,784
Ensembl chr 4:169,556,969...169,558,629 		JBrowse link
G GK5 glycerol kinase 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:139,181,541...139,254,847
Ensembl chr 3:146,789,881...146,849,347 		JBrowse link
G GPAM glycerol-3-phosphate acyltransferase, mitochondrial involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15878874), (PMID:18522808)
(PMID:16935266)		 Ensembl
MGI		 PMID:15878874 PMID:16935266 PMID:18522808 GO_REF:0000107 NCBI chr10:108,747,370...108,781,270
Ensembl chr10:112,186,744...112,246,549 		JBrowse link
G GPAT4 glycerol-3-phosphate acyltransferase 4 acts_upstream_of_or_within ISO (PMID:16436371), (PMID:16449762) MGI PMID:16436371 PMID:16449762 NCBI chr 8:40,822,736...40,869,744
Ensembl chr 8:38,271,808...38,318,587 		JBrowse link
G GPX1 glutathione peroxidase 1 acts_upstream_of_or_within ISO (PMID:12117267) MGI PMID:12117267 NCBI chr 3:49,280,038...49,281,455
Ensembl chr 3:50,360,947...50,361,826 		JBrowse link
G INSIG1 insulin induced gene 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16100574) Ensembl
MGI		 PMID:16100574 GO_REF:0000107 NCBI chr 7:146,893,730...146,906,329
Ensembl chr 7:158,619,531...158,632,012 		JBrowse link
G INSIG2 insulin induced gene 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16100574) Ensembl
MGI		 PMID:16100574 GO_REF:0000107 NCBI chr2B:5,046,971...5,068,757
Ensembl chr2B:118,632,402...118,652,647 		JBrowse link
G LIPA lipase A, lysosomal acid type involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:30639734) Ensembl
MGI		 PMID:30639734 GO_REF:0000107 NCBI chr10:85,938,240...85,976,610
Ensembl chr10:89,477,082...89,516,874 		JBrowse link
G LIPC lipase C, hepatic type ISO RGD PMID:10734075 RGD:1600640 NCBI chr15:37,363,507...37,537,723
Ensembl chr15:55,814,017...55,847,005 		JBrowse link
G LMF1 lipase maturation factor 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:869,449...973,456 JBrowse link
G LOC100969828 glycerol kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:90,975,493...90,978,190 JBrowse link
G LOC100992963 tenascin-X acts_upstream_of_or_within ISO (PMID:15298681) MGI PMID:15298681 NCBI chr 6:31,687,994...31,756,279
Ensembl chr 6:32,571,199...32,626,155 		JBrowse link
G LOC100994952 apolipoprotein C-I, acidic form acts_upstream_of_or_within ISO (PMID:7848292) MGI PMID:7848292 NCBI chr19:41,862,168...41,878,231 JBrowse link
G MTTP microsomal triglyceride transfer protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12072432) Ensembl
MGI		 PMID:12072432 GO_REF:0000107 NCBI chr 4:91,987,756...92,047,127
Ensembl chr 4:102,648,793...102,708,107 		JBrowse link
G NKX2-3 NK2 homeobox 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10926756) Ensembl
MGI		 PMID:10926756 GO_REF:0000107 NCBI chr10:96,146,636...96,150,238 JBrowse link
G PCSK9 proprotein convertase subtilisin/kexin type 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17242417) Ensembl
MGI		 PMID:17242417 GO_REF:0000107 NCBI chr 1:54,323,036...54,355,397
Ensembl chr 1:55,911,016...55,936,456 		JBrowse link
G PLAAT3 phospholipase A and acyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:58,931,593...58,971,269
Ensembl chr11:62,282,487...62,322,736 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 acts_upstream_of_or_within ISO (PMID:15520383) MGI PMID:15520383 NCBI chr12:110,016,364...110,107,462
Ensembl chr12:113,435,669...113,503,762 		JBrowse link
G SEL1L SEL1L adaptor subunit of SYVN1 ubiquitin ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:62,050,695...62,111,489
Ensembl chr14:81,248,441...81,309,597 		JBrowse link
G SLC22A4 solute carrier family 22 member 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10655497) Ensembl
MGI		 PMID:10655497 GO_REF:0000107 NCBI chr 5:127,717,077...127,766,793
Ensembl chr 5:133,879,387...133,929,439 		JBrowse link
G SLC37A4 solute carrier family 37 member 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12925567), (PMID:16891306) Ensembl
MGI		 PMID:12925567 PMID:16891306 GO_REF:0000107 NCBI chr11:113,862,537...113,869,447
Ensembl chr11:117,792,700...117,799,269 		JBrowse link
glycerol biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PCK1 phosphoenolpyruvate carboxykinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11792850) Ensembl
MGI
TreeGrafter		 PMID:11792850 GO_REF:0000107 GO_REF:0000118 NCBI chr20:53,901,738...53,907,090
Ensembl chr20:55,179,429...55,184,920 		JBrowse link
G PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:4,872,276...4,882,118
Ensembl chr14:22,996,813...23,006,775 		JBrowse link
negative regulation of phosphatidate phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LPIN1 lipin 1 ISO RGD PMID:21715287 RGD:38599010 NCBI chr2A:11,664,727...11,815,497
Ensembl chr2A:11,857,961...11,961,551 		JBrowse link
negative regulation of triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR1H4 nuclear receptor subfamily 1 group H member 4 ISO RGD PMID:29148806 RGD:15042869 NCBI chr12:98,052,778...98,144,085
Ensembl chr12:101,457,885...101,548,058 		JBrowse link
G SIK1 salt inducible kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:29,675,040...29,689,408
Ensembl chr21:42,975,920...42,987,948 		JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069 		JBrowse link
G TMX1 thioredoxin related transmembrane protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:31,844,418...31,861,911
Ensembl chr14:50,129,568...50,147,057 		JBrowse link
negative regulation of triglyceride catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOC3 apolipoprotein C3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:111,667,816...111,670,861
Ensembl chr11:115,600,416...115,603,460 		JBrowse link
G GPLD1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISO (MGI:3617276|PMID:16219662) UniProt PMID:16219662 MGI:3617276 NCBI chr 6:24,257,923...24,332,171
Ensembl chr 6:24,588,672...24,665,229 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:21435395 RGD:6482711 NCBI chr 7:98,841,974...98,885,446
Ensembl chr 7:111,570,148...111,611,614 		JBrowse link
G PLIN5 perilipin 5 involved_in ISO (MGI:5476606|PMID:23345411), (MGI:5559662|PMID:22675471) UniProt PMID:22675471 PMID:23345411 MGI:5476606 MGI:5559662 NCBI chr19:3,542,675...3,555,611 JBrowse link
G SORL1 sortilin related receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:116,297,014...116,477,399
Ensembl chr11:120,222,491...120,402,432 		JBrowse link
negative regulation of triglyceride metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOBEC1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 acts_upstream_of_or_within ISO (PMID:9240444) MGI PMID:9240444 NCBI chr12:7,777,734...7,793,960
Ensembl chr12:7,939,262...7,944,203 		JBrowse link
G APOE apolipoprotein E involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9240444) Ensembl
MGI		 PMID:9240444 GO_REF:0000107 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490 		JBrowse link
G CCNC cyclin C ISO RGD PMID:22684109 RGD:9590256 NCBI chr 6:97,383,290...97,410,068
Ensembl chr 6:101,265,499...101,292,233 		JBrowse link
G CDK8 cyclin dependent kinase 8 ISO RGD PMID:22684109 RGD:9590256 NCBI chr13:7,546,922...7,698,079
Ensembl chr13:25,895,705...26,046,120 		JBrowse link
G CIDEC cell death inducing DFFA like effector c involved_in ISO (MGI:3811962|PMID:18682832) UniProt PMID:18682832 MGI:3811962 NCBI chr 3:9,811,995...9,836,069
Ensembl chr 3:10,048,554...10,173,107 		JBrowse link
G ESR1 estrogen receptor 1 ISO RGD PMID:23871901 RGD:8552990 NCBI chr 6:149,507,599...149,918,523
Ensembl chr 6:154,317,002...154,631,551 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:28483554) Ensembl
BHF-UCL		 PMID:28483554 GO_REF:0000107 NCBI chr17:33,458,196...33,484,643
Ensembl chr17:38,405,794...38,432,045 		JBrowse link
positive regulation of triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSL5 acyl-CoA synthetase long chain family member 5 ISO RGD PMID:16263710 RGD:2312807 NCBI chr10:108,965,559...109,019,240
Ensembl chr10:112,407,161...112,457,892 		JBrowse link
G APOC3 apolipoprotein C3 ISO RGD PMID:23542898 RGD:10054091 NCBI chr11:111,667,816...111,670,861
Ensembl chr11:115,600,416...115,603,460 		JBrowse link
G CNEP1R1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:30,288,552...30,300,444
Ensembl chr16:49,172,711...49,184,592 		JBrowse link
G CTDNEP1 CTD nuclear envelope phosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:7,273,460...7,281,158
Ensembl chr17:7,260,803...7,269,003 		JBrowse link
G DGAT1 diacylglycerol O-acyltransferase 1 ISO RGD PMID:23449193 RGD:10400846 NCBI chr 8:141,079,948...141,090,619
Ensembl chr 8:144,064,587...144,080,155 		JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 ISO RGD PMID:17526931 RGD:10400884 NCBI chr11:70,824,791...70,857,530
Ensembl chr11:74,126,169...74,158,854 		JBrowse link
G GPAM glycerol-3-phosphate acyltransferase, mitochondrial ISO RGD PMID:15598672 RGD:2313665 NCBI chr10:108,747,370...108,781,270
Ensembl chr10:112,186,744...112,246,549 		JBrowse link
G GPLD1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISO (MGI:3617276|PMID:16219662) UniProt PMID:16219662 MGI:3617276 NCBI chr 6:24,257,923...24,332,171
Ensembl chr 6:24,588,672...24,665,229 		JBrowse link
G KAT5 lysine acetyltransferase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:61,071,118...61,078,667
Ensembl chr11:64,404,572...64,412,667 		JBrowse link
G LDLR low density lipoprotein receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:10,640,225...10,683,728
Ensembl chr19:11,357,311...11,396,791 		JBrowse link
G MFSD2A MFSD2 lysolipid transporter A, lysophospholipid acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5474727|PMID:23209793) ARUK-UCL
Ensembl		 PMID:23209793 GO_REF:0000107 MGI:5474727 NCBI chr 1:39,244,438...39,259,156
Ensembl chr 1:40,569,706...40,584,438 		JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:47,340,077...47,346,737
Ensembl chr19:56,243,124...56,250,024 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:47,195,122...47,215,277
Ensembl chr11:47,748,353...47,768,672 		JBrowse link
G PLIN5 perilipin 5 involved_in ISO (MGI:5440401|PMID:22532565)
(MGI:3709110|PMID:17130488), (MGI:5559666|PMID:21885430)		 UniProt PMID:17130488 PMID:21885430 PMID:22532565 MGI:3709110 MGI:5440401 MGI:5559666 NCBI chr19:3,542,675...3,555,611 JBrowse link
G RGN regucalcin ISO RGD PMID:16817230 RGD:9590221 NCBI chr  X:39,513,135...39,530,188
Ensembl chr  X:47,371,226...47,388,881 		JBrowse link
G SCARB1 scavenger receptor class B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:122,293,803...122,455,314
Ensembl chr12:126,659,532...126,694,767 		JBrowse link
G SLC27A1 solute carrier family 27 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:16,956,000...16,993,429
Ensembl chr19:17,929,785...17,966,171 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16046411) Ensembl
MGI		 PMID:16046411 GO_REF:0000107 NCBI chr17:33,458,196...33,484,643
Ensembl chr17:38,405,794...38,432,045 		JBrowse link
G TCF7L2 transcription factor 7 like 2 acts_upstream_of_or_within ISO (PMID:23260145) MGI PMID:23260145 NCBI chr10:109,541,524...109,759,499
Ensembl chr10:112,978,167...113,192,281 		JBrowse link
positive regulation of triglyceride catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AADAC arylacetamide deacetylase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:148,820,706...148,853,422
Ensembl chr 3:156,408,950...156,423,847 		JBrowse link
G ABHD5 abhydrolase domain containing 5, lysophosphatidic acid acyltransferase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:43,580,752...43,612,637
Ensembl chr 3:44,640,215...44,669,885 		JBrowse link
G APOA4 apolipoprotein A4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:111,659,186...111,661,790
Ensembl chr11:115,591,788...115,594,382 		JBrowse link
G APOA5 apolipoprotein A5 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:111,625,403...111,627,932
Ensembl chr11:115,559,231...115,562,286 		JBrowse link
G APOC2 apolipoprotein C2 involved_in ISO (PMID:10727238) BHF-UCL PMID:10727238 NCBI chr19:41,892,954...41,896,461 JBrowse link
G APOH apolipoprotein H ISO RGD PMID:7078428 RGD:8554677 NCBI chr17:60,154,389...60,171,762
Ensembl chr17:65,365,250...65,382,483 		JBrowse link
G DAGLB diacylglycerol lipase beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:6,995,425...7,034,279
Ensembl chr 7:6,605,250...6,634,169 		JBrowse link
G FGF21 fibroblast growth factor 21 ISO RGD PMID:23262585 RGD:10401916 NCBI chr19:45,755,466...45,758,472 JBrowse link
G LDLR low density lipoprotein receptor ISO RGD PMID:28469073 RGD:12910100 NCBI chr19:10,640,225...10,683,728
Ensembl chr19:11,357,311...11,396,791 		JBrowse link
G PNPLA2 patatin like phospholipase domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:838,339...844,035
Ensembl chr11:881,934...886,896 		JBrowse link
G SIRT1 sirtuin 1 involved_in ISO (PMID:23296834) AgBase PMID:23296834 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069 		JBrowse link
positive regulation of triglyceride metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD36 CD36 molecule (CD36 blood group) ISO RGD PMID:23099442 RGD:11041154 NCBI chr 7:72,566,478...72,643,517
Ensembl chr 7:86,265,114...86,305,865 		JBrowse link
regulation of triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:5,708,211...5,753,178
Ensembl chr19:6,629,287...6,674,699 		JBrowse link
G FITM2 fat storage inducing transmembrane protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:40,633,898...40,642,300
Ensembl chr20:41,730,346...41,735,389 		JBrowse link
G THRSP thyroid hormone responsive involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:73,123,030...73,128,461
Ensembl chr11:76,747,547...76,747,987 		JBrowse link
regulation of triglyceride metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E ISO RGD PMID:9225228 RGD:10059686 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490 		JBrowse link
G ATG14 autophagy related 14 acts_upstream_of_or_within ISO (PMID:22992773) MGI PMID:22992773 NCBI chr14:35,953,228...35,998,650
Ensembl chr14:54,226,720...54,272,018 		JBrowse link
G GNB3 G protein subunit beta 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:6,971,854...6,979,214
Ensembl chr12:6,883,280...6,890,692 		JBrowse link
G LMF1 lipase maturation factor 1 acts_upstream_of_or_within ISO (PMID:17994020), (PMID:6857276) MGI PMID:6857276 PMID:17994020 Ensembl chr16:869,449...973,456 JBrowse link
G MBOAT7 membrane bound O-acyltransferase domain containing 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:51,107,197...51,121,968
Ensembl chr19:59,949,428...59,963,312 		JBrowse link
G PANK2 pantothenate kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:3,924,054...3,959,393
Ensembl chr20:3,723,211...3,757,748 		JBrowse link
G SERPINA12 serpin family A member 12 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22837305) Ensembl
MGI		 PMID:22837305 GO_REF:0000107 NCBI chr14:75,110,414...75,141,569
Ensembl chr14:94,442,931...94,473,779 		JBrowse link
G TBL1XR1 TBL1X/Y related 1 acts_upstream_of_or_within ISO (PMID:23499424) MGI PMID:23499424 NCBI chr 3:174,067,964...174,251,913
Ensembl chr 3:182,247,335...182,429,619 		JBrowse link
G THRB thyroid hormone receptor beta ISO RGD PMID:17878314 RGD:2315101 NCBI chr 3:24,024,025...24,401,024
Ensembl chr 3:24,346,824...24,564,960 		JBrowse link
triglyceride acyl-chain remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PNPLA3 patatin like phospholipase domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:24,812,831...24,836,161
Ensembl chr22:43,004,499...43,027,003 		JBrowse link
triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSL1 acyl-CoA synthetase long chain family member 1 ISO RGD PMID:16466685 RGD:2312800 NCBI chr 4:176,920,811...176,991,495
Ensembl chr 4:189,145,403...189,198,646 		JBrowse link
G ACSL4 acyl-CoA synthetase long chain family member 4 ISO RGD PMID:16466685 RGD:2312800 NCBI chr  X:98,731,109...98,841,067
Ensembl chr  X:109,206,964...109,310,914 		JBrowse link
G ACSL6 acyl-CoA synthetase long chain family member 6 ISO RGD PMID:16466685 RGD:2312800 NCBI chr 5:127,373,306...127,434,954
Ensembl chr 5:133,537,292...133,586,711 		JBrowse link
G AGMO alkylglycerol monooxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:15,863,957...16,219,070
Ensembl chr 7:15,180,426...15,549,016 		JBrowse link
G AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:107,749,195...107,763,033
Ensembl chr 9:136,722,914...136,737,286 		JBrowse link
G DGAT1 diacylglycerol O-acyltransferase 1 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:18458083) RGD
TreeGrafter
InterPro
Ensembl
MGI		 PMID:14596837 PMID:18458083 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:1625586 NCBI chr 8:141,079,948...141,090,619
Ensembl chr 8:144,064,587...144,080,155 		JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14668353)
(PMID:11481335), (PMID:12077311)		 Ensembl
MGI
TreeGrafter		 PMID:11481335 PMID:12077311 PMID:14668353 GO_REF:0000107 GO_REF:0000118 NCBI chr11:70,824,791...70,857,530
Ensembl chr11:74,126,169...74,158,854 		JBrowse link
G GK glycerol kinase involved_in ISO (PMID:9302256) MGI PMID:9302256 NCBI chr  X:23,250,290...23,327,373
Ensembl chr  X:30,806,950...30,877,131 		JBrowse link
G GNPAT glyceronephosphate O-acyltransferase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:206,794,245...206,830,840
Ensembl chr 1:211,819,259...211,855,885 		JBrowse link
G GPAM glycerol-3-phosphate acyltransferase, mitochondrial involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:108,747,370...108,781,270
Ensembl chr10:112,186,744...112,246,549 		JBrowse link
G GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial acts_upstream_of_or_within ISO (PMID:17689486) MGI PMID:17689486 NCBI chr2A:103,278,885...103,293,021 JBrowse link
G GPAT3 glycerol-3-phosphate acyltransferase 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:40,590,801...40,660,527
Ensembl chr 4:46,438,848...46,506,455 		JBrowse link
G GPAT4 glycerol-3-phosphate acyltransferase 4 NOT|involved_in ISO
IEA		 (PMID:18238778) UniProt
TreeGrafter		 PMID:18238778 GO_REF:0000118 NCBI chr 8:40,822,736...40,869,744
Ensembl chr 8:38,271,808...38,318,587 		JBrowse link
G LOC100977471 glycerol-3-phosphate acyltransferase 2, mitochondrial-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2A:103,472,381...103,483,074 JBrowse link
G LOC100991224 glycerol-3-phosphate acyltransferase 4-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:6,194,418...6,195,471 JBrowse link
G LPGAT1 lysophosphatidylglycerol acyltransferase 1 involved_in ISO (MGI:6467683|PMID:20018982) UniProt PMID:20018982 MGI:6467683 NCBI chr 1:187,312,071...187,399,145
Ensembl chr 1:192,179,164...192,262,799 		JBrowse link
G LPIN1 lipin 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr2A:11,664,727...11,815,497
Ensembl chr2A:11,857,961...11,961,551 		JBrowse link
G LPIN2 lipin 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr18:11,270,941...11,367,312
Ensembl chr18:13,608,883...13,675,165 		JBrowse link
G LPIN3 lipin 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:37,682,636...37,702,357
Ensembl chr20:38,778,695...38,798,502 		JBrowse link
G LPL lipoprotein lipase ISO RGD PMID:11788374 RGD:70246 NCBI chr 8:19,164,541...19,193,100
Ensembl chr 8:16,113,415...16,142,966 		JBrowse link
G MOGAT1 monoacylglycerol O-acyltransferase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2B:109,912,603...109,951,322
Ensembl chr2B:228,493,571...228,531,678 		JBrowse link
G MOGAT2 monoacylglycerol O-acyltransferase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12576479) Ensembl
MGI
TreeGrafter		 PMID:12576479 GO_REF:0000107 GO_REF:0000118 NCBI chr11:70,779,443...70,792,409
Ensembl chr11:74,079,287...74,092,710 		JBrowse link
G MOGAT3 monoacylglycerol O-acyltransferase 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:93,337,040...93,342,822
Ensembl chr 7:106,577,727...106,582,799 		JBrowse link
G PNPLA3 patatin like phospholipase domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:24,812,831...24,836,161
Ensembl chr22:43,004,499...43,027,003 		JBrowse link
G TMEM68 transmembrane protein 68 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:52,135,766...52,214,537
Ensembl chr 8:49,549,593...49,586,260 		JBrowse link
triglyceride catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA5 apolipoprotein A5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:111,625,403...111,627,932
Ensembl chr11:115,559,231...115,562,286 		JBrowse link
G APOB apolipoprotein B acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16455790) RGD
MGI
Ensembl		 PMID:9290048 PMID:16455790 GO_REF:0000107 RGD:1626404 NCBI chr2A:20,986,464...21,029,004
Ensembl chr2A:21,100,356...21,145,129 		JBrowse link
G APOC3 apolipoprotein C3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11590213) Ensembl
MGI		 PMID:11590213 GO_REF:0000107 NCBI chr11:111,667,816...111,670,861
Ensembl chr11:115,600,416...115,603,460 		JBrowse link
G CPS1 carbamoyl-phosphate synthase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:97,735,486...97,936,623
Ensembl chr2B:216,136,857...216,337,728 		JBrowse link
G DDHD2 DDHD domain containing 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25267624) Ensembl
MGI		 PMID:25267624 GO_REF:0000107 NCBI chr 8:37,533,579...37,564,864
Ensembl chr 8:34,711,446...34,741,471 		JBrowse link
G GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:139,960,255...139,964,189
Ensembl chr 8:142,980,151...142,985,429 		JBrowse link
G LIPC lipase C, hepatic type involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr15:37,363,507...37,537,723
Ensembl chr15:55,814,017...55,847,005 		JBrowse link
G LIPE lipase E, hormone sensitive type acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:11717312), (PMID:17074755)
(PMID:16804080)		 RGD
MGI
TreeGrafter
UniProt		 PMID:11717312 PMID:14739077 PMID:16804080 PMID:17074755 GO_REF:0000041 GO_REF:0000118 RGD:1581873 NCBI chr19:39,289,162...39,315,067
Ensembl chr19:47,881,292...47,907,066 		JBrowse link
G LIPG lipase G, endothelial type involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr18:42,942,132...42,972,112
Ensembl chr18:46,292,154...46,320,652 		JBrowse link
G LOC100993654 pancreatic lipase-related protein 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:113,203,170...113,216,890
Ensembl chr10:116,634,538...116,658,075 		JBrowse link
G LPL lipoprotein lipase involved_in IEA UniProt
TreeGrafter
Ensembl		 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:19,164,541...19,193,100
Ensembl chr 8:16,113,415...16,142,966 		JBrowse link
G PLA1A phospholipase A1 member A involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:116,720,777...116,752,030
Ensembl chr 3:123,633,173...123,664,383 		JBrowse link
G PLB1 phospholipase B1 involved_in ISO PMID:9442065
PMID:9442064		 UniProt PMID:9442064 PMID:9442065 RGD:30309923 RGD:633237 NCBI chr2A:28,502,449...28,650,348
Ensembl chr2A:28,584,636...28,730,640 		JBrowse link
G PNPLA1 patatin like phospholipase domain containing 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:35,828,778...35,872,129
Ensembl chr 6:37,002,466...37,067,190 		JBrowse link
G PNPLA2 patatin like phospholipase domain containing 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17074755) Ensembl
MGI
TreeGrafter		 PMID:17074755 GO_REF:0000107 GO_REF:0000118 NCBI chr11:838,339...844,035
Ensembl chr11:881,934...886,896 		JBrowse link
G PNPLA3 patatin like phospholipase domain containing 3 involved_in IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr22:24,812,831...24,836,161
Ensembl chr22:43,004,499...43,027,003 		JBrowse link
G PNPLA4 patatin like phospholipase domain containing 4 involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr  X:7,756,047...7,786,634 JBrowse link
G PNPLA5 patatin like phospholipase domain containing 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr22:24,753,811...24,780,581
Ensembl chr22:42,959,988...42,972,328 		JBrowse link
triglyceride mobilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOB apolipoprotein B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10893242) Ensembl
MGI
TreeGrafter		 PMID:10893242 GO_REF:0000107 GO_REF:0000118 NCBI chr2A:20,986,464...21,029,004
Ensembl chr2A:21,100,356...21,145,129 		JBrowse link
G APOC3 apolipoprotein C3 acts_upstream_of_or_within ISO (PMID:8864964)
(PMID:11551841)		 MGI PMID:8864964 PMID:11551841 NCBI chr11:111,667,816...111,670,861
Ensembl chr11:115,600,416...115,603,460 		JBrowse link
G IL6ST interleukin 6 cytokine family signal transducer ISO RGD PMID:8843746 RGD:1626687 NCBI chr 5:58,023,704...58,081,895
Ensembl chr 5:59,669,606...59,708,817 		JBrowse link
G LPIN1 lipin 1 involved_in ISO (MGI:3770090|PMID:16950137) UniProt PMID:16950137 MGI:3770090 NCBI chr2A:11,664,727...11,815,497
Ensembl chr2A:11,857,961...11,961,551 		JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069 		JBrowse link
G SLC27A5 solute carrier family 27 member 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16618416) Ensembl
MGI		 PMID:16618416 GO_REF:0000107 NCBI chr19:55,507,455...55,520,448
Ensembl chr19:64,329,567...64,342,630 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16313
    cellular process 15397
      cellular metabolic process 8945
        cellular lipid metabolic process 981
          neutral lipid metabolic process 149
            acylglycerol metabolic process 148
              triglyceride metabolic process 118
                negative regulation of triglyceride metabolic process + 17
                positive regulation of triglyceride metabolic process + 30
                regulation of triglyceride metabolic process + 53
                triglyceride acyl-chain remodeling 1
                triglyceride biosynthetic process + 50
                triglyceride catabolic process + 31
                triglyceride mobilization 6
Path 2
Term Annotations click to browse term
  biological_process 16313
    metabolic process 10179
      primary metabolic process 8792
        lipid metabolic process 1297
          cellular lipid metabolic process 981
            neutral lipid metabolic process 149
              acylglycerol metabolic process 148
                triglyceride metabolic process 118
                  negative regulation of triglyceride metabolic process + 17
                  positive regulation of triglyceride metabolic process + 30
                  regulation of triglyceride metabolic process + 53
                  triglyceride acyl-chain remodeling 1
                  triglyceride biosynthetic process + 50
                  triglyceride catabolic process + 31
                  triglyceride mobilization 6
paths to the root