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ONTOLOGY REPORT - ANNOTATIONS


Term:unsaturated fatty acid biosynthetic process
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Accession:GO:0006636 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms.
Synonyms:exact_synonym: unsaturated fatty acid anabolism;   unsaturated fatty acid biosynthesis;   unsaturated fatty acid formation;   unsaturated fatty acid synthesis
 narrow_synonym: polyunsaturated fatty acid biosynthesis
 related_synonym: fatty acid desaturation
 xref: MetaCyc:PWY-762;   MetaCyc:PWY-782


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unsaturated fatty acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Decr2 2-4-dienoyl-Coenzyme A reductase 2, peroxisomal JBrowse link 17 26,081,208 26,090,322 RGD:2290270
G Fads1 fatty acid desaturase 1 JBrowse link 19 10,182,877 10,196,874 RGD:2290270
G Scd1 stearoyl-Coenzyme A desaturase 1 JBrowse link 19 44,394,450 44,407,709 RGD:2290270
G Scd2 stearoyl-Coenzyme A desaturase 2 JBrowse link 19 44,293,676 44,306,864 RGD:2290270
G Scd3 stearoyl-coenzyme A desaturase 3 JBrowse link 19 44,203,288 44,244,016 RGD:2290270
G Scd4 stearoyl-coenzyme A desaturase 4 JBrowse link 19 44,333,326 44,346,743 RGD:2290270
cyclooxygenase pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 2 36,216,742 36,258,593 RGD:2290270
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 150,100,031 150,108,234 RGD:2290270
G Sphk1 sphingosine kinase 1 JBrowse link 11 116,530,836 116,536,675 RGD:2290270
hepoxilin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox12 arachidonate 12-lipoxygenase JBrowse link 11 70,241,457 70,255,380 RGD:2290270
G Alox12b arachidonate 12-lipoxygenase, 12R type JBrowse link 11 69,157,072 69,169,791 RGD:2290270
G Alox12e arachidonate lipoxygenase, epidermal JBrowse link 11 70,315,610 70,322,720 RGD:2290270
G Alox15 arachidonate 15-lipoxygenase JBrowse link 11 70,344,147 70,390,538 RGD:2290270
G Alox5 arachidonate 5-lipoxygenase JBrowse link 6 116,410,071 116,461,178 RGD:2290270
G Alox8 arachidonate 8-lipoxygenase JBrowse link 11 69,183,885 69,197,843 RGD:2290270
G Aloxe3 arachidonate lipoxygenase 3 JBrowse link 11 69,125,417 69,149,115 RGD:2290270
leukotriene A4 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox5 arachidonate 5-lipoxygenase JBrowse link 6 116,410,071 116,461,178 RGD:2290270
lipoxin A4 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox12 arachidonate 12-lipoxygenase JBrowse link 11 70,241,457 70,255,380 RGD:2290270
G Alox15 arachidonate 15-lipoxygenase JBrowse link 11 70,344,147 70,390,538 RGD:2290270
lipoxin B4 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox12 arachidonate 12-lipoxygenase JBrowse link 11 70,241,457 70,255,380 RGD:2290270
lipoxin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox5 arachidonate 5-lipoxygenase JBrowse link 6 116,410,071 116,461,178 RGD:2290270
monounsaturated fatty acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Scd1 stearoyl-Coenzyme A desaturase 1 JBrowse link 19 44,394,450 44,407,709 RGD:2290270
G Scd2 stearoyl-Coenzyme A desaturase 2 JBrowse link 19 44,293,676 44,306,864 RGD:2290270
G Scd3 stearoyl-coenzyme A desaturase 3 JBrowse link 19 44,203,288 44,244,016 RGD:2290270
G Scd4 stearoyl-coenzyme A desaturase 4 JBrowse link 19 44,333,326 44,346,743 RGD:2290270
negative regulation of prostaglandin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pibf1 progesterone immunomodulatory binding factor 1 JBrowse link 14 99,099,424 99,254,899 RGD:2290270
G Sirt1 sirtuin 1 JBrowse link 10 63,319,005 63,339,035 RGD:2290270
positive regulation of prostaglandin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa1 annexin A1 JBrowse link 19 20,373,434 20,390,671 RGD:2290270
G Avp arginine vasopressin JBrowse link 2 130,580,620 130,582,588 RGD:2290270
G Avpr1a arginine vasopressin receptor 1A JBrowse link 10 122,448,499 122,453,453 RGD:2290270
G Cd74 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) JBrowse link 18 60,803,849 60,812,652 RGD:2290270
G Il1b interleukin 1 beta JBrowse link 2 129,364,569 129,371,164 RGD:2290270
G Mapk9 mitogen-activated protein kinase 9 JBrowse link 11 49,846,728 49,886,421 RGD:2290270
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) JBrowse link 1 149,829,618 149,961,290 RGD:2290270
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 150,100,031 150,108,234 RGD:2290270
positive regulation of unsaturated fatty acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcd1 ATP-binding cassette, sub-family D (ALD), member 1 JBrowse link X 73,716,597 73,738,534 RGD:2290270
G Abcd2 ATP-binding cassette, sub-family D (ALD), member 2 JBrowse link 15 91,145,871 91,192,007 RGD:2290270
prostaglandin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd74 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) JBrowse link 18 60,803,849 60,812,652 RGD:2290270
G Edn1 endothelin 1 JBrowse link 13 42,301,476 42,307,990 RGD:2290270
G Edn2 endothelin 2 JBrowse link 4 120,161,206 120,167,360 RGD:2290270
G Hpgds hematopoietic prostaglandin D synthase JBrowse link 6 65,117,293 65,144,981 RGD:2290270
G Mgst1 microsomal glutathione S-transferase 1 JBrowse link 6 138,140,527 138,156,755 RGD:2290270
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) JBrowse link 10 75,859,353 75,860,277 RGD:2290270
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) JBrowse link 1 149,829,618 149,961,290 RGD:2290270
G Pla2g4f phospholipase A2, group IVF JBrowse link 2 120,299,952 120,314,165 RGD:2290270
G Pnpla8 patatin-like phospholipase domain containing 8 JBrowse link 12 44,269,132 44,315,936 RGD:2290270
G Prxl2b peroxiredoxin like 2B JBrowse link 4 154,896,430 154,899,043 RGD:2290270
G Ptgds prostaglandin D2 synthase (brain) JBrowse link 2 25,466,709 25,470,110 RGD:2290270
G Ptges prostaglandin E synthase JBrowse link 2 30,889,471 30,931,020 RGD:2290270
G Ptges2 prostaglandin E synthase 2 JBrowse link 2 32,395,890 32,402,740 RGD:2290270
G Ptges3 prostaglandin E synthase 3 JBrowse link 10 128,058,982 128,077,254 RGD:2290270
G Ptgis prostaglandin I2 (prostacyclin) synthase JBrowse link 2 167,203,194 167,252,150 RGD:2290270
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 2 36,216,742 36,258,593 RGD:2290270
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 150,100,031 150,108,234 RGD:2290270
G Tbxas1 thromboxane A synthase 1, platelet JBrowse link 6 38,864,159 39,084,590 RGD:2290270
regulation of prostaglandin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fabp5 fatty acid binding protein 5, epidermal JBrowse link 3 10,012,585 10,016,610 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23101
    metabolic process 10604
      biosynthetic process 5282
        organic substance biosynthetic process 5171
          lipid biosynthetic process 561
            fatty acid biosynthetic process 134
              unsaturated fatty acid biosynthetic process 42
                (R)-2-hydroxy-alpha-linolenic acid biosynthetic process 0
                hepoxilin biosynthetic process 7
                leukotriene A4 biosynthetic process 1
                leukotriene B4 biosynthetic process 0
                lipoxin biosynthetic process + 3
                monounsaturated fatty acid biosynthetic process 4
                positive regulation of unsaturated fatty acid biosynthetic process + 10
                prostanoid biosynthetic process + 27
                regulation of unsaturated fatty acid biosynthetic process + 13
Path 2
Term Annotations click to browse term
  biological_process 23101
    metabolic process 10604
      small molecule metabolic process 1676
        organic acid metabolic process 965
          oxoacid metabolic process 938
            carboxylic acid metabolic process 897
              monocarboxylic acid metabolic process 588
                fatty acid metabolic process 388
                  fatty acid biosynthetic process 134
                    unsaturated fatty acid biosynthetic process 42
                      (R)-2-hydroxy-alpha-linolenic acid biosynthetic process 0
                      hepoxilin biosynthetic process 7
                      leukotriene A4 biosynthetic process 1
                      leukotriene B4 biosynthetic process 0
                      lipoxin biosynthetic process + 3
                      monounsaturated fatty acid biosynthetic process 4
                      positive regulation of unsaturated fatty acid biosynthetic process + 10
                      prostanoid biosynthetic process + 27
                      regulation of unsaturated fatty acid biosynthetic process + 13
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.