ONTOLOGY REPORT - ANNOTATIONS
Term: fatty acid beta-oxidation
Accession: GO:0006635
browse the term
Definition: A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and occurs by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A; the cycle continues until only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
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Abcd1
ATP binding cassette subfamily D member 1
involved_in
ISO
(PMID:23671276) (PMID:18757502), (PMID:21145416) (PMID:17542813), (PMID:9425230) (MGI:5315378|PMID:10196381)
UniProt
PMID:9425230 PMID:10196381 PMID:17542813 PMID:18757502 PMID:21145416 PMID:23671276 More...
MGI:5315378
NCBI chrNW_004624946:421,113...439,961
Ensembl chrNW_004624946:421,132...440,075
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Abcd2
ATP binding cassette subfamily D member 2
involved_in
IEA
TreeGrafter Ensembl
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004624778:854,297...912,498
Ensembl chrNW_004624778:847,879...909,727
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Abcd3
ATP binding cassette subfamily D member 3
involved_in
IEA
TreeGrafter Ensembl
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004624742:3,146,000...3,236,473
Ensembl chrNW_004624742:3,142,570...3,236,728
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Abcd4
ATP binding cassette subfamily D member 4
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624734:27,309,280...27,324,658
Ensembl chrNW_004624734:27,309,184...27,327,200
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Acaa1
acetyl-CoA acyltransferase 1
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624731:2,665,228...2,677,248
Ensembl chrNW_004624731:2,665,228...2,676,497
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Acaa2
acetyl-CoA acyltransferase 2
ISO
RGD
PMID:11879205
RGD:2317624
NCBI chrNW_004624778:13,307,236...13,336,347
Ensembl chrNW_004624778:13,307,094...13,336,120
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Acadm
acyl-CoA dehydrogenase medium chain
involved_in
ISO
(PMID:2393404)
UniProt
PMID:2393404
NCBI chrNW_004624742:21,188,062...21,215,436
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Acadvl
acyl-CoA dehydrogenase very long chain
ISO
RGD
PMID:8034667
RGD:631729
NCBI chrNW_004624786:9,838,102...9,843,506
Ensembl chrNW_004624786:9,838,227...9,843,332
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Acat1
acetyl-CoA acetyltransferase 1
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624784:2,833,344...2,879,043
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Acat2
acetyl-CoA acetyltransferase 2
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624855:3,177,402...3,199,634
Ensembl chrNW_004624855:3,176,171...3,199,705
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Acox1
acyl-CoA oxidase 1
involved_in
IEA
UniProt
GO_REF:0000117
NCBI chrNW_004624801:5,844,824...5,867,439
Ensembl chrNW_004624801:5,846,729...5,867,427
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Acox2
acyl-CoA oxidase 2
involved_in
ISO IEA
RGD InterPro UniProt
PMID:1400324 PMID:8654595
GO_REF:0000002 GO_REF:0000117 RGD:2299949 RGD:2299971
NCBI chrNW_004624822:5,535,086...5,561,867
Ensembl chrNW_004624822:5,536,421...5,561,781
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Acox3
acyl-CoA oxidase 3, pristanoyl
involved_in
IEA
UniProt
GO_REF:0000117
NCBI chrNW_004624755:23,995,256...24,026,581
Ensembl chrNW_004624755:23,995,089...24,024,083
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Adipoq
adiponectin, C1Q and collagen domain containing
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:12151381)
Ensembl MGI
PMID:12151381
GO_REF:0000107
NCBI chrNW_004624730:69,941,963...69,959,266
Ensembl chrNW_004624730:69,941,001...69,957,012
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Aldh1l2
aldehyde dehydrogenase 1 family member L2
acts_upstream_of_or_within_positive_effect
ISO
(MGI:6489626|PMID:33168096)
UniProt
PMID:33168096
MGI:6489626
NCBI chrNW_004624750:3,912,030...4,054,170
Ensembl chrNW_004624750:3,912,002...3,961,963
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Bdh2
3-hydroxybutyrate dehydrogenase 2
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624830:4,991,689...5,006,911
Ensembl chrNW_004624830:4,991,714...5,006,783
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Cpt1a
carnitine palmitoyltransferase 1A
involved_in
ISO IEA
RGD UniProt
PMID:31901136 PMID:31953200
GO_REF:0000041 RGD:25823178 RGD:25823179
NCBI chrNW_004624767:18,109,011...18,161,378
Ensembl chrNW_004624767:18,109,008...18,161,639
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Cpt1b
carnitine palmitoyltransferase 1B
involved_in
IEA
UniProt
GO_REF:0000041
NCBI chrNW_004624752:191,539...200,483
Ensembl chrNW_004624752:190,462...201,880
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Cpt1c
carnitine palmitoyltransferase 1C
involved_in
IEA
UniProt
GO_REF:0000041
NCBI chrNW_004624832:4,578,400...4,592,933
Ensembl chrNW_004624832:4,577,620...4,591,550
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Cpt2
carnitine palmitoyltransferase 2
involved_in
IEA ISO
TreeGrafter UniProt RGD
PMID:10380116 PMID:10796071
GO_REF:0000041 GO_REF:0000118 RGD:21410186 RGD:2326088
NCBI chrNW_004624934:1,239,849...1,271,993
Ensembl chrNW_004624934:1,250,956...1,271,983
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Crot
carnitine O-octanoyltransferase
involved_in
IEA
Ensembl UniProt
GO_REF:0000041 GO_REF:0000107
NCBI chrNW_004624739:34,696,516...34,738,143
Ensembl chrNW_004624739:34,696,511...34,730,419
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Decr1
2,4-dienoyl-CoA reductase 1
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624744:1,965,605...2,003,299
Ensembl chrNW_004624744:1,963,825...2,003,643
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Ech1
enoyl-CoA hydratase 1
involved_in
IEA
UniProt
GO_REF:0000041
NCBI chrNW_004624794:12,196,402...12,203,674
Ensembl chrNW_004624794:12,195,385...12,203,606
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Echdc1
ethylmalonyl-CoA decarboxylase 1
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624753:1,707,116...1,750,708
Ensembl chrNW_004624753:1,708,153...1,740,824
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Echdc2
enoyl-CoA hydratase domain containing 2
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624859:283,436...299,489
Ensembl chrNW_004624859:283,412...299,489
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Echs1
enoyl-CoA hydratase, short chain 1
involved_in
IEA ISO
TreeGrafter RGD
PMID:12379132
GO_REF:0000118 RGD:2317616
NCBI chrNW_004624737:13,329,052...13,338,358
Ensembl chrNW_004624737:13,328,904...13,338,366
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Eci1
enoyl-CoA delta isomerase 1
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:11916962)
TreeGrafter MGI
PMID:11916962
GO_REF:0000118
NCBI chrNW_004624824:53,174...66,986
Ensembl chrNW_004624824:53,458...66,946
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Eci2
enoyl-CoA delta isomerase 2
ISO
RGD
PMID:11781327
RGD:2306199
NCBI chrNW_004624756:21,003,768...21,021,461
Ensembl chrNW_004624756:21,005,073...21,021,457
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Ehhadh
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:17442273)
TreeGrafter MGI UniProt
PMID:17442273
GO_REF:0000041 GO_REF:0000117 GO_REF:0000118
NCBI chrNW_004624730:71,323,713...71,354,805
Ensembl chrNW_004624730:71,323,484...71,357,109
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Hadh
hydroxyacyl-CoA dehydrogenase
involved_in
IEA ISO
TreeGrafter RGD
PMID:17491019
GO_REF:0000118 RGD:2302227
NCBI chrNW_004624830:1,429,989...1,451,447
Ensembl chrNW_004624830:1,426,775...1,451,440
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Hadha
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
acts_upstream_of_or_within involved_in
ISO IEA
(PMID:11390422)
RGD MGI UniProt InterPro Ensembl
PMID:1730633 PMID:11390422
GO_REF:0000002 GO_REF:0000041 GO_REF:0000107 GO_REF:0000117 RGD:1600572
NCBI chrNW_004624738:8,338,250...8,384,701
Ensembl chrNW_004624738:8,338,250...8,384,704
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Hadhb
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
involved_in
IEA ISO
TreeGrafter RGD
PMID:1730633
GO_REF:0000118 RGD:1600572
NCBI chrNW_004624738:8,384,789...8,420,994
Ensembl chrNW_004624738:8,384,830...8,424,163
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Hsd17b10
hydroxysteroid 17-beta dehydrogenase 10
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624909:681,731...684,130
Ensembl chrNW_004624909:681,731...684,237
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Hsd17b4
hydroxysteroid 17-beta dehydrogenase 4
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:17442273)
TreeGrafter MGI UniProt Ensembl
PMID:17442273
GO_REF:0000041 GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004624733:2,126,124...2,204,966
Ensembl chrNW_004624733:2,124,825...2,205,378
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Lep
leptin
acts_upstream_of_or_within involved_in
ISO IEA
(PMID:22958918)
MGI Ensembl
PMID:22958918
GO_REF:0000107
NCBI chrNW_004624783:7,708,820...7,721,610
Ensembl chrNW_004624783:7,708,588...7,721,727
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LOC101714191
3-ketoacyl-CoA thiolase B, peroxisomal
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624773:19,991,168...20,001,111
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Pex2
peroxisomal biogenesis factor 2
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624744:14,227,430...14,245,082
Ensembl chrNW_004624744:14,240,570...14,245,183
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Pex5
peroxisomal biogenesis factor 5
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:9288097) (PMID:17442273)
Ensembl MGI
PMID:9288097 PMID:17442273
GO_REF:0000107
NCBI chrNW_004624860:3,771,949...3,790,982
Ensembl chrNW_004624860:3,771,963...3,790,985
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Pex7
peroxisomal biogenesis factor 7
acts_upstream_of_or_within
ISO
(PMID:12915479)
MGI
PMID:12915479
NCBI chrNW_004624886:877,359...944,365
Ensembl chrNW_004624886:876,787...944,911
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Ppard
peroxisome proliferator activated receptor delta
involved_in
ISO
(MGI:3688371|PMID:14676330)
UniProt
PMID:14676330
MGI:3688371
NCBI chrNW_004624754:22,021,465...22,084,320
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Scp2
sterol carrier protein 2
involved_in
ISO
PMID:9325339
UniProt
PMID:9325339
RGD:21201257
NCBI chrNW_004624859:106,405...252,870
Ensembl chrNW_004624859:107,258...252,756
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Sesn2
sestrin 2
acts_upstream_of_or_within
ISO
(PMID:22958918)
MGI
PMID:22958918
NCBI chrNW_004624764:12,087,901...12,135,145
Ensembl chrNW_004624764:12,087,858...12,120,914
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Slc25a17
solute carrier family 25 member 17
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624752:7,670,918...7,727,015
Ensembl chrNW_004624752:7,670,951...7,726,655
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Slc27a2
solute carrier family 27 member 2
involved_in
ISO
(PMID:10198260)
UniProt
PMID:10198260
NCBI chrNW_004624731:9,862,948...9,896,064
Ensembl chrNW_004624731:9,862,731...9,896,661
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Acad10
acyl-CoA dehydrogenase family member 10
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624747:20,464,100...20,526,131
Ensembl chrNW_004624747:20,464,499...20,520,492
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Acad11
acyl-CoA dehydrogenase family member 11
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624730:8,704,458...8,792,678
Ensembl chrNW_004624730:8,704,350...8,792,741
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Acadl
acyl-CoA dehydrogenase long chain
involved_in
ISO
(PMID:15639194) (MGI:3526480|PMID:15639194)
RGD BHF-UCL
PMID:3968063 PMID:15639194
MGI:3526480 RGD:2317678
NCBI chrNW_004624765:6,018,534...6,050,736
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Acadm
acyl-CoA dehydrogenase medium chain
involved_in
ISO
(PMID:18459129) (PMID:1902818), (PMID:19224950), (PMID:25416781), (PMID:3597357) (PMID:16972171) (MGI:4412440|PMID:18459129)
BHF-UCL RGD
PMID:1902818 PMID:3597357 PMID:3968063 PMID:16972171 PMID:18459129 PMID:19224950 PMID:25416781 More...
MGI:4412440 RGD:2317678
NCBI chrNW_004624742:21,188,062...21,215,436
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Acads
acyl-CoA dehydrogenase short chain
involved_in
IEA ISO
TreeGrafter RGD
PMID:3968063
GO_REF:0000118 RGD:2317678
NCBI chrNW_004624747:12,954,635...12,966,320
Ensembl chrNW_004624747:12,955,118...12,966,242
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Acadvl
acyl-CoA dehydrogenase very long chain
involved_in
ISO
(PMID:7668252) (PMID:9599005) (MGI:3526480|PMID:15639194)
BHF-UCL UniProt
PMID:7668252 PMID:9599005 PMID:15639194
MGI:3526480
NCBI chrNW_004624786:9,838,102...9,843,506
Ensembl chrNW_004624786:9,838,227...9,843,332
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Etfa
electron transfer flavoprotein subunit alpha
involved_in
IEA
TreeGrafter Ensembl
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004624894:1,874,859...1,935,587
Ensembl chrNW_004624894:1,874,695...1,936,120
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Etfb
electron transfer flavoprotein subunit beta
involved_in
IEA
TreeGrafter Ensembl
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004624832:3,506,140...3,518,760
Ensembl chrNW_004624832:3,505,511...3,518,870
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Etfdh
electron transfer flavoprotein dehydrogenase
involved_in
ISO
(PMID:17412732)
BHF-UCL
PMID:17412732
NCBI chrNW_004624848:3,639,559...3,673,771
Ensembl chrNW_004624848:3,639,294...3,677,517
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Gcdh
glutaryl-CoA dehydrogenase
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624901:474,836...479,674
Ensembl chrNW_004624901:475,073...479,292
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Acox1
acyl-CoA oxidase 1
involved_in
IEA ISO
TreeGrafter InterPro RGD
PMID:1400324
GO_REF:0000002 GO_REF:0000118 RGD:2299949
NCBI chrNW_004624801:5,844,824...5,867,439
Ensembl chrNW_004624801:5,846,729...5,867,427
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Acox2
acyl-CoA oxidase 2
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624822:5,535,086...5,561,867
Ensembl chrNW_004624822:5,536,421...5,561,781
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Acox3
acyl-CoA oxidase 3, pristanoyl
involved_in
IEA ISO
TreeGrafter RGD InterPro
PMID:1400324 PMID:8026493 PMID:8654595
GO_REF:0000002 GO_REF:0000118 RGD:2299949 RGD:2299969 RGD:2299971
NCBI chrNW_004624755:23,995,256...24,026,581
Ensembl chrNW_004624755:23,995,089...24,024,083
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Crat
carnitine O-acetyltransferase
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624760:6,002,032...6,013,489
Ensembl chrNW_004624760:6,002,568...6,013,491
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Acacb
acetyl-CoA carboxylase beta
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624747:12,287,817...12,426,340
Ensembl chrNW_004624747:12,307,541...12,424,897
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Akt1
AKT serine/threonine kinase 1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624734:507,880...525,295
Ensembl chrNW_004624734:509,368...525,295
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Cnr1
cannabinoid receptor 1
ISO
RGD
PMID:19724020
RGD:2314644
NCBI chrNW_004624799:6,100,709...6,126,530
Ensembl chrNW_004624799:6,101,728...6,126,520
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Dbi
diazepam binding inhibitor, acyl-CoA binding protein
ISO
RGD
PMID:11485163
RGD:2316274
NCBI chrNW_004624732:25,764,260...25,769,453
Ensembl chrNW_004624732:25,764,260...25,769,419
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Mfsd2a
MFSD2 lysolipid transporter A, lysophospholipid
acts_upstream_of_or_within
ISO
(MGI:5474727|PMID:23209793)
ARUK-UCL
PMID:23209793
MGI:5474727
NCBI chrNW_004624764:22,422,520...22,435,332
Ensembl chrNW_004624764:22,422,423...22,435,416
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Pink1
PTEN induced kinase 1
ISO
RGD
PMID:25421206
RGD:11560775
NCBI chrNW_004624764:5,656,207...5,671,260
Ensembl chrNW_004624764:5,656,229...5,671,260
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Plin5
perilipin 5
involved_in
ISO
(MGI:5559662|PMID:22675471), (MGI:5559666|PMID:21885430) (MGI:5440401|PMID:22532565)
UniProt
PMID:21885430 PMID:22532565 PMID:22675471
MGI:5440401 MGI:5559662 MGI:5559666
NCBI chrNW_004624828:5,208,060...5,218,553
Ensembl chrNW_004624828:5,207,937...5,218,901
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Etfbkmt
electron transfer flavoprotein subunit beta lysine methyltransferase
involved_in
ISO
(PMID:25023281) (MGI:5700285|PMID:25023281) (PMID:25416781)
UniProt
PMID:25023281 PMID:25416781
MGI:5700285
NCBI chrNW_004624933:958,332...970,785
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Abcd1
ATP binding cassette subfamily D member 1
involved_in
ISO
(PMID:23123468) (MGI:3835692|PMID:18854420), (MGI:3836690|PMID:18723473), (MGI:6189665|PMID:23123468)
UniProt
PMID:18723473 PMID:18854420 PMID:23123468
MGI:3835692 MGI:3836690 MGI:6189665
NCBI chrNW_004624946:421,113...439,961
Ensembl chrNW_004624946:421,132...440,075
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Abcd2
ATP binding cassette subfamily D member 2
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624778:854,297...912,498
Ensembl chrNW_004624778:847,879...909,727
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Acsl5
acyl-CoA synthetase long chain family member 5
ISO
RGD
PMID:14711823
RGD:2312802
NCBI chrNW_004624737:34,038,610...34,091,579
Ensembl chrNW_004624737:34,038,518...34,091,661
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Akt2
AKT serine/threonine kinase 2
involved_in
ISO
(PMID:16814735)
BHF-UCL
PMID:16814735
NCBI chrNW_004624925:262,590...322,440
Ensembl chrNW_004624925:273,881...326,984
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Cpt1a
carnitine palmitoyltransferase 1A
ISO
RGD
PMID:19302064
RGD:2311346
NCBI chrNW_004624767:18,109,011...18,161,378
Ensembl chrNW_004624767:18,109,008...18,161,639
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Irs1
insulin receptor substrate 1
involved_in
ISO
(PMID:16814735)
BHF-UCL
PMID:16814735
NCBI chrNW_004624843:1,113,075...1,178,859
Ensembl chrNW_004624843:1,120,974...1,178,859
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Irs2
insulin receptor substrate 2
involved_in
ISO
(PMID:16814735)
BHF-UCL
PMID:16814735
NCBI chrNW_004624793:2,615,092...2,636,835
Ensembl chrNW_004624793:2,614,589...2,636,947
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Plin5
perilipin 5
involved_in
ISO
(MGI:3709110|PMID:17130488) PMID:22127648
UniProt
PMID:17130488 PMID:22127648
MGI:3709110 RGD:8553692
NCBI chrNW_004624828:5,208,060...5,218,553
Ensembl chrNW_004624828:5,207,937...5,218,901
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Twist1
twist family bHLH transcription factor 1
involved_in
ISO
(PMID:20007935)
BHF-UCL
PMID:20007935
NCBI chrNW_004624739:11,352,040...11,354,019
Ensembl chrNW_004624739:11,352,141...11,352,809
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Abcb11
ATP binding cassette subfamily B member 11
involved_in
ISO
(MGI:5442473|PMID:22619174)
UniProt
PMID:22619174
MGI:5442473
NCBI chrNW_004624787:6,653,849...6,733,058
Ensembl chrNW_004624787:6,650,772...6,733,195
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Abcd1
ATP binding cassette subfamily D member 1
involved_in
ISO
(PMID:25255441), (PMID:9126326), (PMID:9256488), (PMID:9418970) (MGI:1095802|PMID:9256488), (MGI:1101351|PMID:9418970), (MGI:5635749|PMID:25255441), (MGI:87573|PMID:9126326)
UniProt
PMID:9126326 PMID:9256488 PMID:9418970 PMID:25255441
MGI:1095802 MGI:1101351 MGI:5635749 MGI:87573
NCBI chrNW_004624946:421,113...439,961
Ensembl chrNW_004624946:421,132...440,075
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Lonp2
lon peptidase 2, peroxisomal
involved_in
ISO
(PMID:22002062)
UniProt
PMID:22002062
NCBI chrNW_004624914:2,041,353...2,155,669
Ensembl chrNW_004624914:2,041,213...2,155,669
G
Mlycd
malonyl-CoA decarboxylase
ISO
RGD
PMID:10516138
RGD:1600797
NCBI chrNW_004624746:3,604,773...3,619,790
Ensembl chrNW_004624746:3,604,773...3,619,775
G
Mtor
mechanistic target of rapamycin kinase
ISO
RGD
PMID:17142137
RGD:1625611
NCBI chrNW_004624818:1,570,155...1,698,264
Ensembl chrNW_004624818:1,570,276...1,698,259
G
Tysnd1
trypsin like peroxisomal matrix peptidase 1
involved_in
ISO
(PMID:22002062)
UniProt
PMID:22002062
NCBI chrNW_004624754:4,304,955...4,312,155
Ensembl chrNW_004624754:4,300,710...4,312,145
G
Acox1
acyl-CoA oxidase 1
involved_in
ISO
(PMID:32169171)
UniProt
PMID:32169171
NCBI chrNW_004624801:5,844,824...5,867,439
Ensembl chrNW_004624801:5,846,729...5,867,427
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all