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ONTOLOGY REPORT - ANNOTATIONS


Term:protein targeting to vacuole
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Accession:GO:0006623 term browser browse the term
Definition:The process of directing proteins towards the vacuole, usually using signals contained within the protein.
Synonyms:exact_synonym: protein vacuolar targeting;   protein-vacuole targeting;   vacuolar protein sorting


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protein targeting to vacuole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07006458.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 1:235,387,153...235,405,831 JBrowse link
G Ap3d1 adaptor related protein complex 3 subunit delta 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:11,838,639...11,873,992
Ensembl chr 7:11,838,639...11,873,984
JBrowse link
G Mon1a MON1 homolog A, secretory trafficking associated involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 8:116,657,345...116,682,172
Ensembl chr 8:116,657,371...116,682,178
JBrowse link
G Mon1b MON1 homolog B, secretory trafficking associated involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr19:45,938,433...45,946,647
Ensembl chr19:45,938,915...45,945,741
JBrowse link
G Pik3r4 phosphoinositide-3-kinase, regulatory subunit 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:114,300,248...114,350,686
Ensembl chr 8:114,300,257...114,350,681
JBrowse link
G Rnf215 ring finger protein 215 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:84,368,440...84,374,879
Ensembl chr14:84,368,476...84,374,879
JBrowse link
G Vps13c vacuolar protein sorting 13 homolog C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:73,682,814...73,843,290
Ensembl chr 8:73,682,887...73,842,928
JBrowse link
G Vps13d vacuolar protein sorting 13 homolog D involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:162,891,451...163,119,239
Ensembl chr 5:162,891,451...163,119,239
JBrowse link
G Vps37a VPS37A subunit of ESCRT-I involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:54,860,811...54,899,410
Ensembl chr16:54,860,868...54,899,347
JBrowse link
G Vps37b VPS37B subunit of ESCRT-I involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:37,984,790...38,023,369
Ensembl chr12:37,984,790...38,023,368
JBrowse link
G Vps37c VPS37C subunit of ESCRT-I involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:226,742,267...226,774,109
Ensembl chr 1:226,742,343...226,767,868
JBrowse link
G Vps37d VPS37D subunit of ESCRT-I involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:24,651,342...24,656,793
Ensembl chr12:24,651,314...24,656,793
JBrowse link
G Vps41 VPS41 subunit of HOPS complex involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:48,643,754...48,810,633
Ensembl chr17:48,648,879...48,810,991
JBrowse link
N-glycan processing to lysosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnptab N-acetylglucosamine-1-phosphate transferase subunits alpha and beta involved_in ISO
IBA
(PMID:19938078), (PMID:25505245)
PMID:21873635
RGD PMID:19938078 PMID:25505245, PMID:21873635 RGD:13792537 NCBI chr 7:28,956,363...29,023,232
Ensembl chr 7:28,956,512...29,022,868
JBrowse link
protein targeting to lysosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap3b1 adaptor related protein complex 3 subunit beta 1 acts_upstream_of_or_within ISO MGI:1856989 (MGI:2679144|PMID:14557411) RGD PMID:14557411 MGI:2679144 NCBI chr 2:24,022,815...24,227,522
Ensembl chr 2:24,024,791...24,226,224
JBrowse link
G Ap4m1 adaptor related protein complex 4 subunit mu 1 involved_in ISO (PMID:11139587) RGD PMID:11139587 NCBI chr12:19,314,222...19,320,339
Ensembl chr12:19,314,251...19,320,142
JBrowse link
G Gcc2 GRIP and coiled-coil domain containing 2 involved_in ISO
IEA
ISS
(PMID:16885419)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:16885419 GO_REF:0000024 GO_REF:0000107 NCBI chr20:27,832,960...27,879,764
Ensembl chr20:27,832,932...27,879,759
JBrowse link
G Gga3 golgi associated, gamma adaptin ear containing, ARF binding protein 3 involved_in ISO UniProtKB:P46934 (PMID:17116753) RGD PMID:17116753 NCBI chr10:104,137,655...104,156,576
Ensembl chr10:104,137,655...104,156,576
JBrowse link
G Hgs hepatocyte growth factor-regulated tyrosine kinase substrate involved_in ISO
IEA
(PMID:18767904)
GO_REF:0000107
RGD
Ensembl
PMID:18767904 GO_REF:0000107 NCBI chr10:109,638,944...109,657,460
Ensembl chr10:109,638,767...109,657,456
JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (MGI:3803048|PMID:18619870) RGD PMID:18619870 MGI:3803048 NCBI chr 5:149,015,793...149,069,719
Ensembl chr 5:149,047,681...149,069,719
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor IMP chorionic gonadotropin after receptor internalization RGD PMID:10847593 RGD:2292601 NCBI chr 6:12,493,182...12,554,482
Ensembl chr 6:12,493,943...12,554,439
JBrowse link
G M6pr mannose-6-phosphate receptor, cation dependent involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:155,084,755...155,093,896
Ensembl chr 4:155,088,317...155,092,827
Ensembl chr  X:155,088,317...155,092,827
JBrowse link
G Ncoa4 nuclear receptor coactivator 4 acts_upstream_of_or_within ISO (PMID:25327288) RGD PMID:25327288 NCBI chr16:8,302,950...8,323,294
Ensembl chr16:8,302,950...8,323,293
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase involved_in ISO
IEA
UniProtKB:Q9NZ52 (PMID:17116753)
GO_REF:0000107
RGD
Ensembl
PMID:17116753 GO_REF:0000107 NCBI chr 8:79,323,408...79,408,842
Ensembl chr 8:79,323,408...79,408,833
JBrowse link
G Rab7a RAB7A, member RAS oncogene family involved_in ISO (PMID:22115783) RGD PMID:22115783 NCBI chr 4:119,910,461...119,963,065
Ensembl chr 4:119,910,478...119,959,173
JBrowse link
G Scarb2 scavenger receptor class B, member 2 involved_in IBA
ISO
PMID:21873635
(MGI:3773765|PMID:18022370)
(PMID:18022370)
RGD PMID:18022370, PMID:21873635 MGI:3773765, RGD:13792537 NCBI chr14:17,064,173...17,115,620
Ensembl chr14:17,064,353...17,115,963
JBrowse link
G Snx16 sorting nexin 16 involved_in ISO
IEA
ISS
IBA
(PMID:12813048)
GO_REF:0000107
GO_REF:0000024
PMID:21873635
RGD
Ensembl
UniProt
PMID:12813048, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 2:93,518,796...93,541,056
Ensembl chr 2:93,518,806...93,540,328
JBrowse link
G Sorl1 sortilin related receptor 1 involved_in ISO (PMID:24523320) RGD PMID:24523320 NCBI chr 8:46,228,077...46,287,171 JBrowse link
G Sort1 sortilin 1 acts_upstream_of_or_within ISO MGI:4397584 (MGI:4368056|PMID:19732768) RGD PMID:19732768 MGI:4368056 NCBI chr 2:211,078,092...211,156,312
Ensembl chr 2:211,078,334...211,156,312
JBrowse link
G Vps4a vacuolar protein sorting 4 homolog A involved_in ISO (PMID:16973552) RGD PMID:16973552 NCBI chr19:39,230,050...39,243,298
Ensembl chr19:39,229,754...39,243,496
JBrowse link
G Zfyve16 zinc finger FYVE-type containing 16 involved_in ISO
IBA
(PMID:11546807)
PMID:21873635
RGD PMID:11546807, PMID:21873635 RGD:13792537 NCBI chr 2:22,060,879...22,105,822
Ensembl chr 2:22,062,050...22,105,710
JBrowse link
protein targeting to lysosome involved in chaperone-mediated autophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07011951.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 2:177,651,241...177,653,288 JBrowse link
G AABR07033324.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr11:17,336,444...17,340,373 JBrowse link
G AABR07048992.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 5:99,031,013...99,033,107 JBrowse link
G Clu clusterin involved_in ISO
IEA
(PMID:9228033)
GO_REF:0000107
RGD
Ensembl
PMID:9228033 GO_REF:0000107 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Hsc70-ps1 heat shock cognate protein 70, pseudogene 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:177,651,231...177,653,349 JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 involved_in IBA
ISO
PMID:21873635
(PMID:26212789)
RGD PMID:26212789, PMID:21873635 RGD:13792537 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 involved_in
acts_upstream_of_or_within
ISO
IGI
IMP
IBA
ISS
(PMID:27628032)
PMID:18644871
PMID:21873635
(MGI:5805578|PMID:27628032)
GO_REF:0000024
RGD
UniProt
PMID:27628032, PMID:18644871, PMID:18644871, PMID:21873635 GO_REF:0000024 MGI:5805578, RGD:10412301, RGD:10412301, RGD:13792537 NCBI chr  X:124,722,628...124,766,079
Ensembl chr  X:124,722,628...124,766,044
JBrowse link
G LOC100363133 heat shock cognate 71 kDa protein-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:99,030,998...99,033,110 JBrowse link
G LOC680121 similar to heat shock protein 8 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:13,499,168...13,501,271
Ensembl chr11:13,499,164...13,501,263
JBrowse link
protein targeting to vacuole involved in autophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 involved_in ISO (PMID:22020285) RGD PMID:22020285 NCBI chr12:11,433,815...11,526,465
Ensembl chr12:11,407,213...11,526,465
JBrowse link
regulation of protein targeting to vacuolar membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vamp7 vesicle-associated membrane protein 7 acts_upstream_of_or_within ISO (MGI:3774712|PMID:18227281) RGD PMID:18227281 MGI:3774712 NCBI chr12:18,996,566...19,033,714
Ensembl chr12:18,996,591...19,030,381
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    cellular process 18344
      vacuolar transport 163
        protein targeting to vacuole 42
          cytoplasm to vacuole transport by the Cvt pathway + 0
          cytoplasm to vacuole transport by the NVT pathway 0
          protein targeting to lysosome + 27
          protein targeting to vacuolar membrane + 1
          protein targeting to vacuole involved in autophagy + 10
Path 2
Term Annotations click to browse term
  biological_process 19491
    cellular process 18344
      cellular localization 2990
        cellular macromolecule localization 1854
          cellular protein localization 1840
            protein localization to organelle 938
              establishment of protein localization to organelle 455
                establishment of protein localization to vacuole 54
                  protein targeting to vacuole 42
                    cytoplasm to vacuole transport by the Cvt pathway + 0
                    cytoplasm to vacuole transport by the NVT pathway 0
                    protein targeting to lysosome + 27
                    protein targeting to vacuolar membrane + 1
                    protein targeting to vacuole involved in autophagy + 10
paths to the root