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ONTOLOGY REPORT - ANNOTATIONS

Term:protein retention in ER lumen
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Accession:GO:0006621 term browser browse the term
Definition:The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER.
Synonyms:broad_synonym: maintenance of protein location in ER lumen


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protein retention in ER lumen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd13c ankyrin repeat domain 13C involved_in ISO
IBA		 (PMID:20959461)
GO_REF:0000033		 RGD
GO_Central		 PMID:20959461 GO_REF:0000033 NCBI chr 2:247,023,040...247,070,433
Ensembl chr 2:247,022,286...247,070,433 		JBrowse link
G ENSRNOG00000063781 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 5:127,376,764...127,398,397 JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 involved_in IMP PMID:12878702 UniProt PMID:12878702 RGD:2316545 NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125 		JBrowse link
G Kdelr1 KDEL endoplasmic reticulum protein retention receptor 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:96,347,258...96,358,145
Ensembl chr 1:96,347,150...96,358,157 		JBrowse link
G Kdelr2 KDEL endoplasmic reticulum protein retention receptor 2 involved_in IEA
IBA		 GO_REF:0000002
GO_REF:0000118
GO_REF:0000033		 InterPro
TreeGrafter
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr12:11,138,820...11,157,117
Ensembl chr12:11,138,820...11,157,153 		JBrowse link
G Kdelr3 KDEL endoplasmic reticulum protein retention receptor 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:111,079,236...111,089,463
Ensembl chr 7:111,079,218...111,101,600 		JBrowse link
G LOC102553980 ankyrin repeat domain-containing protein 13C-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:162,511,274...162,515,628 JBrowse link
G Os9 OS9, endoplasmic reticulum lectin involved_in ISS
ISO		 GO_REF:0000024
(PMID:18417469)		 UniProt
RGD		 PMID:18417469 GO_REF:0000024 NCBI chr 7:62,915,498...62,957,591
Ensembl chr 7:62,915,515...62,943,745 		JBrowse link
G Rer1 retention in endoplasmic reticulum sorting receptor 1 involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 5:165,634,567...165,646,643
Ensembl chr 5:165,634,300...165,646,750 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    cellular process 18812
      maintenance of location in cell 267
        maintenance of protein location in cell 82
          maintenance of protein localization in organelle 50
            maintenance of protein localization in endoplasmic reticulum 16
              protein retention in ER lumen 9
Path 2
Term Annotations click to browse term
  biological_process 20413
    cellular process 18812
      cellular localization 3776
        cellular macromolecule localization 2760
          protein localization 2748
            maintenance of protein location 106
              maintenance of protein location in cell 82
                maintenance of protein localization in organelle 50
                  maintenance of protein localization in endoplasmic reticulum 16
                    protein retention in ER lumen 9
paths to the root