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ONTOLOGY REPORT - ANNOTATIONS


Term:post-translational protein targeting to endoplasmic reticulum membrane
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Accession:GO:0006620 term browser browse the term
Definition:The targeting of proteins to a membrane that occurs after their translation. Some secretory proteins exhibit posttranslational transport into the endoplasmic reticulum (ER) lumen: they are synthesized in their entirety on free cytosolic ribosomes and then released into the cytosol, where they are bound by chaperones which keep them in an unfolded state, and subsequently are translocated across the ER membrane.
Synonyms:exact_synonym: SRP-independent endoplasmic reticulum protein-membrane targeting;   posttranslational endoplasmic reticulum membrane targeting;   posttranslational endoplasmic reticulum protein-membrane targeting;   posttranslational protein targeting to ER membrane;   posttranslational protein targeting to endoplasmic reticulum membrane



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post-translational protein targeting to endoplasmic reticulum membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag6 BAG cochaperone 6 involved_in ISO
IEA
(PMID:25535373)
GO_REF:0000107
RGD
Ensembl
PMID:25535373 GO_REF:0000107 NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657
JBrowse link
G Chmp4b charged multivesicular body protein 4B involved_in ISO (PMID:21975012) RGD PMID:21975012 NCBI chr 3:143,170,859...143,211,376
Ensembl chr 3:143,170,902...143,210,844
JBrowse link
G ENSRNOG00000066262 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr  X:34,823,863...34,824,157 JBrowse link
G Get1 guided entry of tail-anchored proteins factor 1 acts_upstream_of_or_within ISO MGI:5911419|MGI:6117117 (PMID:27458190) RGD PMID:27458190 NCBI chr11:35,438,555...35,460,156
Ensembl chr11:35,445,815...35,459,973
JBrowse link
G Get3 guided entry of tail-anchored proteins factor 3, ATPase involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr19:23,130,109...23,138,196
Ensembl chr19:23,130,109...23,138,193
JBrowse link
G Get4 guided entry of tail-anchored proteins factor 4 involved_in ISO (PMID:25535373) RGD PMID:25535373 NCBI chr12:15,377,009...15,394,238
Ensembl chr12:15,377,009...15,394,053
JBrowse link
G Macf1 microtubule-actin crosslinking factor 1 acts_upstream_of_or_within ISO (PMID:16815997) RGD PMID:16815997 NCBI chr 5:135,623,734...135,949,097
Ensembl chr 5:135,623,742...135,945,905
JBrowse link
G Sec61a1 SEC61 translocon subunit alpha 1 acts_upstream_of_or_within ISO (PMID:22375059) RGD PMID:22375059 NCBI chr 4:120,973,519...120,987,871
Ensembl chr 4:120,960,626...120,987,925
JBrowse link
G Sec62 SEC62 homolog, preprotein translocation factor acts_upstream_of_or_within ISO (PMID:22375059) RGD PMID:22375059 NCBI chr 2:112,570,810...112,598,198
Ensembl chr 2:112,570,819...112,601,814
JBrowse link
G Sec63 SEC63 homolog, protein translocation regulator acts_upstream_of_or_within
involved_in
ISO
IBA
(PMID:22375059)
MGI:5442171 (PMID:22375059)
GO_REF:0000033
RGD
GO_Central
PMID:22375059 GO_REF:0000033 NCBI chr20:46,245,101...46,314,055
Ensembl chr20:46,245,101...46,314,055
JBrowse link
G Sgta small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IEA
IBA
GO_REF:0000118
GO_REF:0000033
TreeGrafter
GO_Central
GO_REF:0000033 GO_REF:0000118 NCBI chr 7:8,653,681...8,670,460
Ensembl chr 7:8,653,778...8,670,458
JBrowse link
G Sgtb small glutamine rich tetratricopeptide repeat co-chaperone beta involved_in IBA
IEA
GO_REF:0000033
GO_REF:0000118
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000118 NCBI chr 2:35,233,045...35,269,527
Ensembl chr 2:35,233,042...35,269,518
JBrowse link
G Slc10a3 solute carrier family 10, member 3 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr  X:152,154,757...152,158,563
Ensembl chr  X:152,151,076...152,162,958
JBrowse link
G Ubl4a ubiquitin-like 4A involved_in ISO
IBA
IEA
(PMID:25535373)
GO_REF:0000033
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:25535373 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:152,151,242...152,154,094
Ensembl chr  X:152,151,460...152,154,069
JBrowse link
post-translational protein targeting to membrane, translocation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENSRNOG00000064831 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 5:55,583,379...55,585,551 JBrowse link
G ENSRNOG00000067115 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 2:239,449,978...239,457,959 JBrowse link
G Glp1r glucagon-like peptide 1 receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2150310 (PMID:23542788)
Ensembl
RGD
PMID:23542788 GO_REF:0000107 NCBI chr20:8,972,004...9,010,241
Ensembl chr20:8,972,004...9,010,241
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:29719251)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:29719251 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G LOC134478824 protein transport protein Sec61 subunit gamma-like involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118
G Sec61a1 SEC61 translocon subunit alpha 1 involved_in ISS
ISO
IEA
IBA
GO_REF:0000024
(PMID:29719251)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000118
UniProt
RGD
Ensembl
GO_Central
TreeGrafter
PMID:29719251 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:120,973,519...120,987,871
Ensembl chr 4:120,960,626...120,987,925
JBrowse link
G Sec61a2 SEC61 translocon subunit alpha 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:72,407,574...72,445,630
Ensembl chr17:72,407,671...72,434,494
JBrowse link
G Sec61b SEC61 translocon subunit beta involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:61,773,594...61,781,804
Ensembl chr 5:61,773,594...61,781,804
JBrowse link
G Sec61g Sec61 translocon subunit gamma involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:90,899,766...90,906,143
Ensembl chr14:90,899,768...90,906,162
JBrowse link
G Sec61g-ps4 Sec61 translocon subunit gamma, pseudogene 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:113,427,370...113,427,696
Ensembl chr  X:113,427,440...113,427,646
JBrowse link
G Sec61gl1 Sec61 translocon subunit gamma like 1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 8:80,701,029...80,710,125
Ensembl chr 8:80,709,227...80,709,505
JBrowse link
G Sec61gl2 Sec61 translocon subunit gamma like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:75,638,449...75,638,655
Ensembl chr17:75,638,449...75,638,655
JBrowse link
G Sec62 SEC62 homolog, preprotein translocation factor involved_in ISO
IBA
(PMID:29719251)
GO_REF:0000033
RGD
GO_Central
PMID:29719251 GO_REF:0000033 NCBI chr 2:112,570,810...112,598,198
Ensembl chr 2:112,570,819...112,601,814
JBrowse link
G Sec63 SEC63 homolog, protein translocation regulator involved_in ISO (PMID:29719251) RGD PMID:29719251 NCBI chr20:46,245,101...46,314,055
Ensembl chr20:46,245,101...46,314,055
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    localization 5751
      establishment of localization 5029
        establishment of protein localization 1811
          protein targeting 367
            protein targeting to ER 53
              post-translational protein targeting to endoplasmic reticulum membrane 25
                post-translational protein targeting to membrane, docking 0
                post-translational protein targeting to membrane, translocation + 14
Path 2
Term Annotations click to browse term
  biological_process 20413
    localization 5751
      cellular localization 3776
        cellular macromolecule localization 2760
          protein localization 2748
            protein localization to organelle 1115
              protein localization to endoplasmic reticulum 93
                establishment of protein localization to endoplasmic reticulum 57
                  protein targeting to ER 53
                    post-translational protein targeting to endoplasmic reticulum membrane 25
                      post-translational protein targeting to membrane, docking 0
                      post-translational protein targeting to membrane, translocation + 14
paths to the root