ONTOLOGY REPORT - ANNOTATIONS
Term: post-translational protein targeting to endoplasmic reticulum membrane
Accession: GO:0006620
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Definition: The targeting of proteins to a membrane that occurs after their translation. Some secretory proteins exhibit posttranslational transport into the endoplasmic reticulum (ER) lumen: they are synthesized in their entirety on free cytosolic ribosomes and then released into the cytosol, where they are bound by chaperones which keep them in an unfolded state, and subsequently are translocated across the ER membrane.
Synonyms: exact_synonym: SRP-independent endoplasmic reticulum protein-membrane targeting; posttranslational endoplasmic reticulum membrane targeting; posttranslational endoplasmic reticulum protein-membrane targeting; posttranslational protein targeting to ER membrane; posttranslational protein targeting to endoplasmic reticulum membrane
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Bag6
BAG cochaperone 6
involved_in
ISO IEA
(PMID:25535373) GO_REF:0000107
RGD Ensembl
PMID:25535373
GO_REF:0000107
NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657
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Chmp4b
charged multivesicular body protein 4B
involved_in
ISO
(PMID:21975012)
RGD
PMID:21975012
NCBI chr 3:143,170,859...143,211,376
Ensembl chr 3:143,170,902...143,210,844
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ENSRNOG00000066262
involved_in
IEA
GO_REF:0000118
TreeGrafter
GO_REF:0000118
Ensembl chr X:34,823,863...34,824,157
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Get1
guided entry of tail-anchored proteins factor 1
acts_upstream_of_or_within
ISO
MGI:5911419|MGI:6117117 (PMID:27458190)
RGD
PMID:27458190
NCBI chr11:35,438,555...35,460,156
Ensembl chr11:35,445,815...35,459,973
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Get3
guided entry of tail-anchored proteins factor 3, ATPase
involved_in
IEA
GO_REF:0000118
TreeGrafter
GO_REF:0000118
NCBI chr19:23,130,109...23,138,196
Ensembl chr19:23,130,109...23,138,193
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Get4
guided entry of tail-anchored proteins factor 4
involved_in
ISO
(PMID:25535373)
RGD
PMID:25535373
NCBI chr12:15,377,009...15,394,238
Ensembl chr12:15,377,009...15,394,053
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Macf1
microtubule-actin crosslinking factor 1
acts_upstream_of_or_within
ISO
(PMID:16815997)
RGD
PMID:16815997
NCBI chr 5:135,623,734...135,949,097
Ensembl chr 5:135,623,742...135,945,905
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Sec61a1
SEC61 translocon subunit alpha 1
acts_upstream_of_or_within
ISO
(PMID:22375059)
RGD
PMID:22375059
NCBI chr 4:120,973,519...120,987,871
Ensembl chr 4:120,960,626...120,987,925
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Sec62
SEC62 homolog, preprotein translocation factor
acts_upstream_of_or_within
ISO
(PMID:22375059)
RGD
PMID:22375059
NCBI chr 2:112,570,810...112,598,198
Ensembl chr 2:112,570,819...112,601,814
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Sec63
SEC63 homolog, protein translocation regulator
acts_upstream_of_or_within involved_in
ISO IBA
(PMID:22375059) MGI:5442171 (PMID:22375059) GO_REF:0000033
RGD GO_Central
PMID:22375059
GO_REF:0000033
NCBI chr20:46,245,101...46,314,055
Ensembl chr20:46,245,101...46,314,055
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Sgta
small glutamine rich tetratricopeptide repeat co-chaperone alpha
involved_in
IEA IBA
GO_REF:0000118 GO_REF:0000033
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr 7:8,653,681...8,670,460
Ensembl chr 7:8,653,778...8,670,458
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Sgtb
small glutamine rich tetratricopeptide repeat co-chaperone beta
involved_in
IBA IEA
GO_REF:0000033 GO_REF:0000118
GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000118
NCBI chr 2:35,233,045...35,269,527
Ensembl chr 2:35,233,042...35,269,518
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Slc10a3
solute carrier family 10, member 3
involved_in
IEA
GO_REF:0000118
TreeGrafter
GO_REF:0000118
NCBI chr X:152,154,757...152,158,563
Ensembl chr X:152,151,076...152,162,958
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Ubl4a
ubiquitin-like 4A
involved_in
ISO IBA IEA
(PMID:25535373) GO_REF:0000033 GO_REF:0000107
RGD GO_Central Ensembl
PMID:25535373
GO_REF:0000033 GO_REF:0000107
NCBI chr X:152,151,242...152,154,094
Ensembl chr X:152,151,460...152,154,069
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ENSRNOG00000064831
involved_in
IEA
GO_REF:0000118
TreeGrafter
GO_REF:0000118
Ensembl chr 5:55,583,379...55,585,551
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ENSRNOG00000067115
involved_in
IEA
GO_REF:0000118
TreeGrafter
GO_REF:0000118
Ensembl chr 2:239,449,978...239,457,959
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Glp1r
glucagon-like peptide 1 receptor
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:2150310 (PMID:23542788)
Ensembl RGD
PMID:23542788
GO_REF:0000107
NCBI chr20:8,972,004...9,010,241
Ensembl chr20:8,972,004...9,010,241
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Hspa5
heat shock protein family A (Hsp70) member 5
involved_in
ISS ISO IEA
GO_REF:0000024 (PMID:29719251) GO_REF:0000107
UniProt RGD Ensembl
PMID:29719251
GO_REF:0000024 GO_REF:0000107
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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LOC134478824
protein transport protein Sec61 subunit gamma-like
involved_in
IEA
GO_REF:0000118
TreeGrafter
GO_REF:0000118
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Sec61a1
SEC61 translocon subunit alpha 1
involved_in
ISS ISO IEA IBA
GO_REF:0000024 (PMID:29719251) GO_REF:0000107 GO_REF:0000033 GO_REF:0000118
UniProt RGD Ensembl GO_Central TreeGrafter
PMID:29719251
GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118
NCBI chr 4:120,973,519...120,987,871
Ensembl chr 4:120,960,626...120,987,925
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Sec61a2
SEC61 translocon subunit alpha 2
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr17:72,407,574...72,445,630
Ensembl chr17:72,407,671...72,434,494
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Sec61b
SEC61 translocon subunit beta
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 5:61,773,594...61,781,804
Ensembl chr 5:61,773,594...61,781,804
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Sec61g
Sec61 translocon subunit gamma
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr14:90,899,766...90,906,143
Ensembl chr14:90,899,768...90,906,162
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Sec61g-ps4
Sec61 translocon subunit gamma, pseudogene 4
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr X:113,427,370...113,427,696
Ensembl chr X:113,427,440...113,427,646
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Sec61gl1
Sec61 translocon subunit gamma like 1
involved_in
IEA
GO_REF:0000118
TreeGrafter
GO_REF:0000118
NCBI chr 8:80,701,029...80,710,125
Ensembl chr 8:80,709,227...80,709,505
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Sec61gl2
Sec61 translocon subunit gamma like 2
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr17:75,638,449...75,638,655
Ensembl chr17:75,638,449...75,638,655
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Sec62
SEC62 homolog, preprotein translocation factor
involved_in
ISO IBA
(PMID:29719251) GO_REF:0000033
RGD GO_Central
PMID:29719251
GO_REF:0000033
NCBI chr 2:112,570,810...112,598,198
Ensembl chr 2:112,570,819...112,601,814
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Sec63
SEC63 homolog, protein translocation regulator
involved_in
ISO
(PMID:29719251)
RGD
PMID:29719251
NCBI chr20:46,245,101...46,314,055
Ensembl chr20:46,245,101...46,314,055
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