Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:SRP-dependent cotranslational protein targeting to membrane
go back to main search page
Accession:GO:0006614 term browser browse the term
Definition:The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.
Synonyms:exact_synonym: SRP-dependent cotranslational membrane targeting;   SRP-dependent cotranslational protein-membrane targeting
 broad_synonym: ER translocation


show annotations for term's descendants           Sort by:
 
SRP-dependent cotranslational protein targeting to membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC108348180 signal recognition particle subunit SRP72-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:33,958,495...33,960,973
Ensembl chr14:33,447,591...33,560,503
JBrowse link
G Sec61a1 SEC61 translocon subunit alpha 1 acts_upstream_of_or_within ISO (PMID:22375059) RGD PMID:22375059 NCBI chr 4:120,453,577...120,467,932
Ensembl chr 4:120,453,581...120,467,932
JBrowse link
G Sec63 SEC63 homolog, protein translocation regulator involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:22375059)
MGI:5442171 (MGI:5494355|PMID:22375059)
RGD PMID:22375059, PMID:21873635 MGI:5494355, RGD:13792537 NCBI chr20:47,494,270...47,563,222
Ensembl chr20:47,494,270...47,563,222
JBrowse link
G Srp14 signal recognition particle 14 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:110,245,936...110,249,627
Ensembl chr 3:110,245,936...110,249,627
JBrowse link
G Srp68 signal recognition particle 68 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:105,123,324...105,150,080
Ensembl chr10:105,123,327...105,228,547
JBrowse link
G Srp9 signal recognition particle 9 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:100,551,307...100,559,447
Ensembl chr13:100,551,307...100,559,447
JBrowse link
G Srpra SRP receptor subunit alpha involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:36,410,683...36,416,766
Ensembl chr 8:36,410,683...36,416,296
JBrowse link
G Ssr3 signal sequence receptor subunit 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:156,010,997...156,023,853
Ensembl chr 2:156,011,002...156,014,527
JBrowse link
SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Srp19 signal recognition particle 19 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:27,114,822...27,121,062
Ensembl chr18:27,114,822...27,121,059
JBrowse link
G Srp54a signal recognition particle 54A involved_in ISO (PMID:16469117) RGD PMID:16469117 NCBI chr 6:75,996,629...76,035,768
Ensembl chr 6:75,996,643...76,034,083
JBrowse link
SRP-dependent cotranslational protein targeting to membrane, translocation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sec61a1 SEC61 translocon subunit alpha 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:120,453,577...120,467,932
Ensembl chr 4:120,453,581...120,467,932
JBrowse link
G Sec61a2 SEC61 translocon subunit alpha 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:76,358,947...76,385,860
Ensembl chr17:76,358,944...76,385,103
JBrowse link
G Sec61b SEC61 translocon subunit beta involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:63,192,322...63,200,532
Ensembl chr 5:63,192,298...63,200,508
JBrowse link
G Srp54a signal recognition particle 54A involved_in ISO
IBA
(PMID:8521805)
PMID:21873635
RGD PMID:8521805, PMID:21873635 RGD:13792537 NCBI chr 6:75,996,629...76,035,768
Ensembl chr 6:75,996,643...76,034,083
JBrowse link
G Tram1 translocation associated membrane protein 1 involved_in IEA
ISO
GO_REF:0000002
(PMID:8698819)
InterPro
RGD
PMID:8698819 GO_REF:0000002 NCBI chr 5:5,215,196...5,297,337
Ensembl chr 5:5,215,196...5,316,685
JBrowse link
G Tram1l1 translocation associated membrane protein 1-like 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:228,544,418...228,546,599
Ensembl chr 2:228,544,418...228,546,599
JBrowse link
G Tram2 translocation associated membrane protein 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:27,117,861...27,192,166
Ensembl chr 9:27,117,869...27,192,135
JBrowse link
G Zfand2b zinc finger AN1-type containing 2B acts_upstream_of_or_within ISO (PMID:24160817) RGD PMID:24160817 NCBI chr 9:82,370,887...82,373,843
Ensembl chr 9:82,370,924...82,373,839
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    localization 6443
      cellular localization 2990
        intracellular transport 1518
          intracellular protein transport 904
            protein targeting 316
              protein targeting to ER 42
                SRP-dependent cotranslational protein targeting to membrane 16
                  SRP-dependent cotranslational protein targeting to membrane, docking 0
                  SRP-dependent cotranslational protein targeting to membrane, signal sequence processing 0
                  SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition 2
                  SRP-dependent cotranslational protein targeting to membrane, translocation 8
Path 2
Term Annotations click to browse term
  biological_process 19491
    localization 6443
      macromolecule localization 3012
        protein localization 2570
          establishment of protein localization 1693
            protein transport 1568
              intracellular protein transport 904
                protein targeting 316
                  protein targeting to membrane 126
                    cotranslational protein targeting to membrane 17
                      SRP-dependent cotranslational protein targeting to membrane 16
                        SRP-dependent cotranslational protein targeting to membrane, docking 0
                        SRP-dependent cotranslational protein targeting to membrane, signal sequence processing 0
                        SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition 2
                        SRP-dependent cotranslational protein targeting to membrane, translocation 8
paths to the root