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ONTOLOGY REPORT - ANNOTATIONS


Term:polyamine biosynthetic process
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Accession:GO:0006596 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.
Synonyms:exact_synonym: polyamine anabolism;   polyamine biosynthesis;   polyamine formation;   polyamine synthesis
 xref: MetaCyc:POLYAMSYN-PWY


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polyamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sat1 spermidine/spermine N1-acetyltransferase 1 ISO (PMID:15283699) UniProt PMID:15283699 NCBI chrNW_004936624:756,761...759,979 JBrowse link
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 NOT ISO (PMID:15283699) UniProt PMID:15283699 NCBI chrNW_004936595:891,380...892,937 JBrowse link
positive regulation of spermidine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase ISO (PMID:16354669) UniProtKB PMID:16354669 NCBI chrNW_004936486:19,503,631...19,511,918 JBrowse link
putrescine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Odc1 ornithine decarboxylase 1 ISO RGD PMID:1415709, PMID:10430362 RGD:1578320, RGD:7242912 NCBI chrNW_004936532:6,581,717...6,587,116 JBrowse link
G Paox polyamine oxidase ISO (PMID:16354669) UniProtKB PMID:16354669 NCBI chrNW_004936486:19,503,631...19,511,918 JBrowse link
putrescine biosynthetic process from ornithine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Odc1 ornithine decarboxylase 1 ISO (MGI:5574513|PMID:24967154) UniProt PMID:24967154 MGI:5574513 NCBI chrNW_004936532:6,581,717...6,587,116 JBrowse link
spermidine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amd1 adenosylmethionine decarboxylase 1 ISO (MGI:3584197|PMID:11856372) RGD
MGI
PMID:1415709, PMID:10430362, PMID:10712236, PMID:11856372 MGI:3584197, RGD:1578320, RGD:7242911, RGD:7242912 NCBI chrNW_004936564:6,656,789...6,675,564 JBrowse link
G Srm spermidine synthase ISO (PMID:17585781) RGD
UniProtKB
PMID:8494549, PMID:12843627, PMID:16931179, PMID:17585781 RGD:1359042, RGD:7242920, RGD:7242928 NCBI chrNW_004936474:121,135...124,894 JBrowse link
spermine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amd1 adenosylmethionine decarboxylase 1 ISO (MGI:3584197|PMID:11856372) RGD
MGI
PMID:1415709, PMID:10430362, PMID:10712236, PMID:11856372 MGI:3584197, RGD:1578320, RGD:7242911, RGD:7242912 NCBI chrNW_004936564:6,656,789...6,675,564 JBrowse link
G Sms spermine synthase ISO RGD PMID:8494549 RGD:7242928 NCBI chrNW_004936624:2,345,573...2,402,157 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12002
    metabolic process 7668
      nitrogen compound metabolic process 6467
        organonitrogen compound metabolic process 4491
          amine metabolic process 98
            amine biosynthetic process 31
              cellular biogenic amine biosynthetic process 31
                polyamine biosynthetic process 7
                  nor-spermidine biosynthetic process 0
                  putrescine biosynthetic process + 2
                  regulation of polyamine biosynthetic process + 1
                  spermidine biosynthetic process + 3
                  spermine biosynthetic process 2
                  thermospermine biosynthetic process 0
                  trimethylenediamine biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 12002
    metabolic process 7668
      nitrogen compound metabolic process 6467
        organonitrogen compound metabolic process 4491
          amine metabolic process 98
            cellular amine metabolic process 94
              cellular biogenic amine metabolic process 81
                polyamine metabolic process 12
                  polyamine biosynthetic process 7
                    nor-spermidine biosynthetic process 0
                    putrescine biosynthetic process + 2
                    regulation of polyamine biosynthetic process + 1
                    spermidine biosynthetic process + 3
                    spermine biosynthetic process 2
                    thermospermine biosynthetic process 0
                    trimethylenediamine biosynthetic process 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.