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ONTOLOGY REPORT - ANNOTATIONS


Term:polyamine metabolic process
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Accession:GO:0006595 term browser browse the term
Definition:The chemical reactions and pathways involving polyamines, any organic compound containing two or more amino groups.
Synonyms:exact_synonym: polyamine metabolism


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polyamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amd1 adenosylmethionine decarboxylase 1 IDA RGD PMID:10430362 RGD:1578320 NCBI chr20:45,384,000...45,399,694
Ensembl chr20:45,384,000...45,399,694
JBrowse link
G Oaz2 ornithine decarboxylase antizyme 2 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:71,216,011...71,229,788
Ensembl chr 8:71,216,178...71,228,713
JBrowse link
G Odc1 ornithine decarboxylase 1 IDA RGD PMID:10430362 RGD:1578320 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 IDA RGD PMID:11172929 RGD:1599544 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
nor-spermidine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 ISO (PMID:12803540) RGD PMID:12803540 NCBI chr10:56,227,703...56,229,796
Ensembl chr10:56,227,692...56,229,850
JBrowse link
polyamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Azin1 antizyme inhibitor 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:77,345,646...77,372,398
Ensembl chr 7:77,345,646...77,372,398
JBrowse link
G Azin2 antizyme inhibitor 2 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:147,120,128...147,148,576
Ensembl chr 5:147,120,129...147,148,291
JBrowse link
G LOC100912604 spermidine synthase-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:14,588,818...14,591,980
Ensembl chr 3:14,588,870...14,591,974
JBrowse link
G Oaz1 ornithine decarboxylase antizyme 1 IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:11,752,127...11,754,587
Ensembl chr 7:11,752,412...11,754,508
JBrowse link
G Odc1 ornithine decarboxylase 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 ISO (PMID:15283699) RGD PMID:15283699 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 NOT ISO (PMID:15283699) RGD PMID:15283699 NCBI chr10:56,227,703...56,229,796
Ensembl chr10:56,227,692...56,229,850
JBrowse link
G Srm spermidine synthase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:165,405,168...165,408,325
Ensembl chr 5:165,405,168...165,408,320
JBrowse link
polyamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase IDA
ISO
(MGI:2663545|PMID:12660232)
(PMID:12477380)
RGD PMID:12477380, PMID:12660232, PMID:15541750 MGI:2663545, RGD:7244190 NCBI chr 1:212,578,444...212,603,722
Ensembl chr 1:212,578,450...212,603,529
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 IDA RGD PMID:15541750 RGD:7244190 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
G Smox spermine oxidase ISO (PMID:12477380) RGD PMID:12477380 NCBI chr 3:124,068,796...124,103,726
Ensembl chr 3:124,068,865...124,102,240
JBrowse link
polyamine deacetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac10 histone deacetylase 10 ISS
ISO
GO_REF:0000024
(PMID:28516954)
UniProt
RGD
PMID:28516954 GO_REF:0000024 NCBI chr 7:130,102,335...130,109,036
Ensembl chr 7:130,102,347...130,107,437
JBrowse link
G Hdac6 histone deacetylase 6 NOT ISO (PMID:28516954) RGD PMID:28516954 NCBI chr  X:15,295,372...15,316,673
Ensembl chr  X:15,295,473...15,316,671
JBrowse link
positive regulation of spermidine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase ISO (PMID:16354669) RGD PMID:16354669 NCBI chr 1:212,578,444...212,603,722
Ensembl chr 1:212,578,450...212,603,529
JBrowse link
putrescine acetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 ISO (PMID:12803540) RGD PMID:12803540 NCBI chr10:56,227,703...56,229,796
Ensembl chr10:56,227,692...56,229,850
JBrowse link
putrescine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Odc1 ornithine decarboxylase 1 IDA RGD PMID:10430362, PMID:1415709 RGD:1578320, RGD:7242912 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Paox polyamine oxidase ISO (PMID:16354669) RGD PMID:16354669 NCBI chr 1:212,578,444...212,603,722
Ensembl chr 1:212,578,450...212,603,529
JBrowse link
putrescine biosynthetic process from arginine, using agmatinase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agmat agmatinase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:160,306,754...160,321,951
Ensembl chr 5:160,306,727...160,321,066
JBrowse link
putrescine biosynthetic process from ornithine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Azin1 antizyme inhibitor 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:77,345,646...77,372,398
Ensembl chr 7:77,345,646...77,372,398
JBrowse link
G Azin2 antizyme inhibitor 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:147,120,128...147,148,576
Ensembl chr 5:147,120,129...147,148,291
JBrowse link
G Odc1 ornithine decarboxylase 1 IEA
ISO
IBA
ISS
GO_REF:0000041
(MGI:5574513|PMID:24967154)
PMID:21873635
GO_REF:0000024
UniProt
RGD
PMID:24967154, PMID:21873635 GO_REF:0000024, GO_REF:0000041, MGI:5574513, RGD:13792537 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G RGD1562036 similar to ornithine decarboxylase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:148,432,213...148,444,188
Ensembl chr 5:148,433,086...148,444,188
JBrowse link
putrescine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase IDA
ISO
PMID:16354669
(PMID:16354669)
RGD PMID:16354669, PMID:16354669 RGD:12790650 NCBI chr 1:212,578,444...212,603,722
Ensembl chr 1:212,578,450...212,603,529
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
putrescine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aoc1 amine oxidase, copper containing 1 ISO
ISS
(PMID:8144586)
GO_REF:0000024
RGD
UniProt
PMID:8144586 GO_REF:0000024 NCBI chr 4:78,496,043...78,515,582
Ensembl chr 4:78,496,043...78,515,584
JBrowse link
spermidine acetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sat1 spermidine/spermine N1-acetyl transferase 1 IDA
ISO
IBA
(PMID:15283699)
PMID:21873635
RGD PMID:15283699, PMID:15541750, PMID:21873635 RGD:7244190, RGD:13792537 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 NOT ISO
IBA
(PMID:12803540)
(PMID:15283699)
PMID:21873635
RGD PMID:12803540, PMID:15283699, PMID:21873635 RGD:13792537 NCBI chr10:56,227,703...56,229,796
Ensembl chr10:56,227,692...56,229,850
JBrowse link
spermidine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agmat agmatinase IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:160,306,754...160,321,951
Ensembl chr 5:160,306,727...160,321,066
JBrowse link
G Amd1 adenosylmethionine decarboxylase 1 IDA
ISO
IBA
IMP
(MGI:3584197|PMID:11856372)
PMID:21873635
RGD PMID:11856372, PMID:10430362, PMID:21873635, PMID:1415709, PMID:10712236 MGI:3584197, RGD:1578320, RGD:13792537, RGD:7242912, RGD:7242911 NCBI chr20:45,384,000...45,399,694
Ensembl chr20:45,384,000...45,399,694
JBrowse link
G LOC100912604 spermidine synthase-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:14,588,818...14,591,980
Ensembl chr 3:14,588,870...14,591,974
JBrowse link
G Srm spermidine synthase IDA
IBA
ISO
IMP
PMID:21873635
(PMID:17585781)
RGD PMID:17585781, PMID:12843627, PMID:21873635, PMID:8494549, PMID:16931179 RGD:1359042, RGD:13792537, RGD:7242928, RGD:7242920 NCBI chr 5:165,405,168...165,408,325
Ensembl chr 5:165,405,168...165,408,320
JBrowse link
spermidine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhps deoxyhypusine synthase IDA RGD PMID:7721768 RGD:2316236 NCBI chr19:26,184,665...26,188,755
Ensembl chr19:26,184,545...26,188,832
JBrowse link
G Paox polyamine oxidase IDA
ISO
(PMID:16354669) RGD PMID:16354669, PMID:7560898, PMID:16354669 RGD:7244191, RGD:12790650 NCBI chr 1:212,578,444...212,603,722
Ensembl chr 1:212,578,450...212,603,529
JBrowse link
spermidine deacetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac10 histone deacetylase 10 ISS
ISO
GO_REF:0000024
(PMID:28516954)
UniProt
RGD
PMID:28516954 GO_REF:0000024 NCBI chr 7:130,102,335...130,109,036
Ensembl chr 7:130,102,347...130,107,437
JBrowse link
G Hdac6 histone deacetylase 6 NOT ISO (PMID:28516954) RGD PMID:28516954 NCBI chr  X:15,295,372...15,316,673
Ensembl chr  X:15,295,473...15,316,671
JBrowse link
spermidine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhps deoxyhypusine synthase ISO (PMID:23525104) RGD PMID:23525104 NCBI chr19:26,184,665...26,188,755
Ensembl chr19:26,184,545...26,188,832
JBrowse link
spermine acetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sat1 spermidine/spermine N1-acetyl transferase 1 IC RGD PMID:15541750 RGD:7244190 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 ISO (PMID:12803540) RGD PMID:12803540 NCBI chr10:56,227,703...56,229,796
Ensembl chr10:56,227,692...56,229,850
JBrowse link
spermine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amd1 adenosylmethionine decarboxylase 1 IDA
ISO
IBA
IMP
(MGI:3584197|PMID:11856372)
PMID:21873635
RGD PMID:11856372, PMID:10430362, PMID:21873635, PMID:1415709, PMID:10712236 MGI:3584197, RGD:1578320, RGD:13792537, RGD:7242912, RGD:7242911 NCBI chr20:45,384,000...45,399,694
Ensembl chr20:45,384,000...45,399,694
JBrowse link
G Sms spermine synthase IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:8494549, PMID:21873635 RGD:7242928, RGD:13792537 NCBI chr  X:40,363,646...40,415,110
Ensembl chr  X:40,363,646...40,415,109
JBrowse link
spermine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase IDA
ISO
PMID:16354669
(PMID:16354669)
RGD PMID:16354669, PMID:7560898, PMID:16354669 RGD:7244191, RGD:12790650 NCBI chr 1:212,578,444...212,603,722
Ensembl chr 1:212,578,450...212,603,529
JBrowse link
G Smox spermine oxidase IDA
ISO
(MGI:2429361|PMID:12141946)
(PMID:18422650)
RGD PMID:12141946, PMID:18422650, PMID:15541750 MGI:2429361, RGD:7244190 NCBI chr 3:124,068,796...124,103,726
Ensembl chr 3:124,068,865...124,102,240
JBrowse link
spermine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sms spermine synthase ISO MGI:2180359 (MGI:1197776|PMID:9467015) RGD PMID:9467015 MGI:1197776 NCBI chr  X:40,363,646...40,415,110
Ensembl chr  X:40,363,646...40,415,109
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      nitrogen compound metabolic process 10347
        cellular nitrogen compound metabolic process 6684
          cellular amine metabolic process 113
            cellular biogenic amine metabolic process 100
              polyamine metabolic process 19
                atrazine metabolic process + 0
                nor-spermidine metabolic process + 1
                polyamine acetylation + 2
                polyamine biosynthetic process + 13
                polyamine catabolic process + 4
                polyamine deacetylation + 2
                putrescine metabolic process + 9
                spermidine metabolic process + 10
                spermine metabolic process + 6
                thermospermine metabolic process + 0
                trimethylenediamine metabolic process + 0
Path 2
Term Annotations click to browse term
  biological_process 20020
    metabolic process 12263
      organic substance metabolic process 11643
        organonitrogen compound metabolic process 7134
          amine metabolic process 121
            cellular amine metabolic process 113
              cellular biogenic amine metabolic process 100
                polyamine metabolic process 19
                  atrazine metabolic process + 0
                  nor-spermidine metabolic process + 1
                  polyamine acetylation + 2
                  polyamine biosynthetic process + 13
                  polyamine catabolic process + 4
                  polyamine deacetylation + 2
                  putrescine metabolic process + 9
                  spermidine metabolic process + 10
                  spermine metabolic process + 6
                  thermospermine metabolic process + 0
                  trimethylenediamine metabolic process + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.