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ONTOLOGY REPORT - ANNOTATIONS


Term:polyamine metabolic process
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Accession:GO:0006595 term browser browse the term
Definition:The chemical reactions and pathways involving polyamines, any organic compound containing two or more amino groups.
Synonyms:exact_synonym: polyamine metabolism



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polyamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amd1 adenosylmethionine decarboxylase 1 IDA RGD PMID:10430362 RGD:1578320 NCBI chr20:43,695,783...43,711,476
Ensembl chr20:43,697,237...43,711,476
JBrowse link
G Oaz2 ornithine decarboxylase antizyme 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:66,199,694...66,213,513
Ensembl chr 8:66,199,706...66,231,453
JBrowse link
G Odc1 ornithine decarboxylase 1 IDA RGD PMID:10430362 RGD:1578320 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 IDA RGD PMID:11172929 RGD:1599544 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
JBrowse link
nor-spermidine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 involved_in ISO (PMID:12803540) RGD PMID:12803540 NCBI chr10:54,340,756...54,343,507
Ensembl chr10:54,340,372...54,343,224
JBrowse link
polyamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Azin1 antizyme inhibitor 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:69,654,773...69,681,578
Ensembl chr 7:69,654,663...69,681,578
JBrowse link
G Azin2 antizyme inhibitor 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:141,281,310...141,310,415
Ensembl chr 5:141,281,249...141,310,397
JBrowse link
G Oaz1 ornithine decarboxylase antizyme 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:8,883,855...8,886,315
Ensembl chr 7:8,883,851...8,886,310
JBrowse link
G Odc1 ornithine decarboxylase 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 involved_in ISO (PMID:15283699) RGD PMID:15283699 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
JBrowse link
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 NOT|involved_in ISO (PMID:15283699) RGD PMID:15283699 NCBI chr10:54,340,756...54,343,507
Ensembl chr10:54,340,372...54,343,224
JBrowse link
G Srm spermidine synthase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:159,025,919...159,029,076
Ensembl chr 5:159,025,873...159,029,405
JBrowse link
polyamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase acts_upstream_of_or_within
involved_in
IDA
ISO
(MGI:2663545|PMID:12660232)
(PMID:12477380)
RGD PMID:12477380 PMID:12660232 PMID:15541750 MGI:2663545, RGD:7244190 NCBI chr 1:194,903,267...194,928,504
Ensembl chr 1:194,903,273...194,928,504
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 IDA RGD PMID:15541750 RGD:7244190 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
JBrowse link
G Smox spermine oxidase involved_in ISO (PMID:12477380) RGD PMID:12477380 NCBI chr 3:118,731,814...118,767,242
Ensembl chr 3:118,731,900...118,765,710
JBrowse link
polyamine deacetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac10 histone deacetylase 10 involved_in ISS
ISO
GO_REF:0000024
(PMID:28516954)
UniProt
RGD
PMID:28516954 GO_REF:0000024 NCBI chr 7:120,199,126...120,205,850
Ensembl chr 7:120,199,129...120,204,228
JBrowse link
G Hdac6 histone deacetylase 6 NOT|involved_in ISO (PMID:28516954) RGD PMID:28516954 NCBI chr  X:14,550,645...14,572,445
Ensembl chr  X:14,551,044...14,572,441
JBrowse link
positive regulation of spermidine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase involved_in ISO (PMID:16354669) RGD PMID:16354669 NCBI chr 1:194,903,267...194,928,504
Ensembl chr 1:194,903,273...194,928,504
JBrowse link
putrescine acetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 involved_in ISO (PMID:12803540) RGD PMID:12803540 NCBI chr10:54,340,756...54,343,507
Ensembl chr10:54,340,372...54,343,224
JBrowse link
putrescine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Odc1 ornithine decarboxylase 1 IDA RGD PMID:10430362 PMID:1415709 RGD:1578320, RGD:7242912 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Paox polyamine oxidase involved_in ISO (PMID:16354669) RGD PMID:16354669 NCBI chr 1:194,903,267...194,928,504
Ensembl chr 1:194,903,273...194,928,504
JBrowse link
putrescine biosynthetic process from arginine, using agmatinase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agmat agmatinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:154,043,665...154,074,278
Ensembl chr 5:154,060,151...154,074,276
JBrowse link
putrescine biosynthetic process from ornithine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Azin1 antizyme inhibitor 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:69,654,773...69,681,578
Ensembl chr 7:69,654,663...69,681,578
JBrowse link
G Azin2 antizyme inhibitor 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:141,281,310...141,310,415
Ensembl chr 5:141,281,249...141,310,397
JBrowse link
G Odc1 ornithine decarboxylase 1 involved_in ISS
ISO
IBA
IEA
GO_REF:0000024
(MGI:5574513|PMID:24967154)
PMID:21873635
GO_REF:0000041
UniProt
RGD
PMID:24967154 PMID:21873635 GO_REF:0000024 GO_REF:0000041 MGI:5574513, RGD:13792537 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G RGD1562036 similar to ornithine decarboxylase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:142,551,120...142,563,217
Ensembl chr 5:142,552,008...142,563,074
JBrowse link
putrescine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase involved_in ISO
IDA
(PMID:16354669) RGD PMID:16354669 PMID:16354669 RGD:12790650 NCBI chr 1:194,903,267...194,928,504
Ensembl chr 1:194,903,273...194,928,504
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
JBrowse link
putrescine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aoc1 amine oxidase, copper containing 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:8144586)
UniProt
RGD
PMID:8144586 GO_REF:0000024 NCBI chr 4:77,812,260...77,831,846
Ensembl chr 4:77,812,260...77,831,840
JBrowse link
regulation of polyamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nnmt nicotinamide N-methyltransferase involved_in ISO
IEA
(MGI:5565106|PMID:24717514)
GO_REF:0000107
RGD
Ensembl
PMID:24717514 GO_REF:0000107 MGI:5565106 NCBI chr 8:48,928,663...48,947,734
Ensembl chr 8:48,933,598...48,946,655
JBrowse link
spermidine acetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sat1 spermidine/spermine N1-acetyl transferase 1 involved_in IDA
IBA
ISO
PMID:21873635
(PMID:15283699)
RGD PMID:15283699 PMID:15541750 PMID:21873635 RGD:7244190, RGD:13792537 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
JBrowse link
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 involved_in
NOT|involved_in
IBA
ISO
PMID:21873635
(PMID:12803540)
(PMID:15283699)
RGD PMID:12803540 PMID:15283699 PMID:21873635 RGD:13792537 NCBI chr10:54,340,756...54,343,507
Ensembl chr10:54,340,372...54,343,224
JBrowse link
spermidine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agmat agmatinase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:154,043,665...154,074,278
Ensembl chr 5:154,060,151...154,074,276
JBrowse link
G Amd1 adenosylmethionine decarboxylase 1 acts_upstream_of_or_within
involved_in
IDA
ISO
IBA
IMP
(MGI:3584197|PMID:11856372)
PMID:21873635
RGD PMID:11856372 PMID:10430362 PMID:21873635 PMID:1415709 PMID:10712236 MGI:3584197, RGD:1578320, RGD:13792537, RGD:7242912, RGD:7242911 NCBI chr20:43,695,783...43,711,476
Ensembl chr20:43,697,237...43,711,476
JBrowse link
G Srm spermidine synthase involved_in IDA
ISO
IBA
IMP
(PMID:17585781)
PMID:21873635
RGD PMID:17585781 PMID:12843627 PMID:21873635 PMID:8494549 PMID:16931179 RGD:1359042, RGD:13792537, RGD:7242928, RGD:7242920 NCBI chr 5:159,025,919...159,029,076
Ensembl chr 5:159,025,873...159,029,405
JBrowse link
spermidine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhps deoxyhypusine synthase IDA RGD PMID:7721768 RGD:2316236 NCBI chr19:23,082,454...23,086,544
Ensembl chr19:23,082,448...23,086,881
JBrowse link
G Paox polyamine oxidase involved_in IDA
ISO
PMID:16354669
(PMID:16354669)
RGD PMID:16354669 PMID:7560898 PMID:16354669 RGD:7244191, RGD:12790650 NCBI chr 1:194,903,267...194,928,504
Ensembl chr 1:194,903,273...194,928,504
JBrowse link
spermidine deacetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac10 histone deacetylase 10 involved_in ISO
ISS
(PMID:28516954)
GO_REF:0000024
RGD
UniProt
PMID:28516954 GO_REF:0000024 NCBI chr 7:120,199,126...120,205,850
Ensembl chr 7:120,199,129...120,204,228
JBrowse link
G Hdac6 histone deacetylase 6 NOT|involved_in ISO (PMID:28516954) RGD PMID:28516954 NCBI chr  X:14,550,645...14,572,445
Ensembl chr  X:14,551,044...14,572,441
JBrowse link
spermidine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhps deoxyhypusine synthase involved_in ISO (PMID:23525104) RGD PMID:23525104 NCBI chr19:23,082,454...23,086,544
Ensembl chr19:23,082,448...23,086,881
JBrowse link
spermine acetylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sat1 spermidine/spermine N1-acetyl transferase 1 IC RGD PMID:15541750 RGD:7244190 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
JBrowse link
G Sat2 spermidine/spermine N1-acetyltransferase family member 2 involved_in ISO (PMID:12803540) RGD PMID:12803540 NCBI chr10:54,340,756...54,343,507
Ensembl chr10:54,340,372...54,343,224
JBrowse link
spermine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amd1 adenosylmethionine decarboxylase 1 acts_upstream_of_or_within
involved_in
IDA
ISO
IBA
IMP
(MGI:3584197|PMID:11856372)
PMID:21873635
RGD PMID:11856372 PMID:10430362 PMID:21873635 PMID:1415709 PMID:10712236 MGI:3584197, RGD:1578320, RGD:13792537, RGD:7242912, RGD:7242911 NCBI chr20:43,695,783...43,711,476
Ensembl chr20:43,697,237...43,711,476
JBrowse link
G Sms spermine synthase involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:8494549 PMID:21873635 RGD:7242928, RGD:13792537 NCBI chr  X:37,516,949...37,572,657
Ensembl chr  X:37,516,931...37,570,822
JBrowse link
spermine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paox polyamine oxidase involved_in IDA
ISO
PMID:16354669
(PMID:16354669)
RGD PMID:16354669 PMID:7560898 PMID:16354669 RGD:7244191, RGD:12790650 NCBI chr 1:194,903,267...194,928,504
Ensembl chr 1:194,903,273...194,928,504
JBrowse link
G Smox spermine oxidase acts_upstream_of_or_within
involved_in
IDA
ISO
(MGI:2429361|PMID:12141946)
(PMID:18422650)
RGD PMID:12141946 PMID:18422650 PMID:15541750 MGI:2429361, RGD:7244190 NCBI chr 3:118,731,814...118,767,242
Ensembl chr 3:118,731,900...118,765,710
JBrowse link
spermine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sms spermine synthase acts_upstream_of_or_within ISO MGI:2180359 (MGI:1197776|PMID:9467015) RGD PMID:9467015 MGI:1197776 NCBI chr  X:37,516,949...37,572,657
Ensembl chr  X:37,516,931...37,570,822
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19390
    metabolic process 11736
      nitrogen compound metabolic process 9922
        cellular nitrogen compound metabolic process 6503
          cellular amine metabolic process 119
            cellular biogenic amine metabolic process 106
              polyamine metabolic process 19
                atrazine metabolic process + 0
                nor-spermidine metabolic process + 1
                polyamine acetylation + 2
                polyamine biosynthetic process + 13
                polyamine catabolic process + 4
                polyamine deacetylation + 2
                putrescine metabolic process + 9
                spermidine metabolic process + 9
                spermine metabolic process + 6
                thermospermine metabolic process + 0
                trimethylenediamine metabolic process + 0
Path 2
Term Annotations click to browse term
  biological_process 19390
    metabolic process 11736
      organic substance metabolic process 11278
        organonitrogen compound metabolic process 6758
          amine metabolic process 127
            cellular amine metabolic process 119
              cellular biogenic amine metabolic process 106
                polyamine metabolic process 19
                  atrazine metabolic process + 0
                  nor-spermidine metabolic process + 1
                  polyamine acetylation + 2
                  polyamine biosynthetic process + 13
                  polyamine catabolic process + 4
                  polyamine deacetylation + 2
                  putrescine metabolic process + 9
                  spermidine metabolic process + 9
                  spermine metabolic process + 6
                  thermospermine metabolic process + 0
                  trimethylenediamine metabolic process + 0
paths to the root