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ONTOLOGY REPORT - ANNOTATIONS

Term:catecholamine metabolic process
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Accession:GO:0006584 term browser browse the term
Definition:The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.
Synonyms:exact_synonym: catecholamine metabolism


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catecholamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856098 (MGI:54307|PMID:17511) RGD PMID:17511 MGI:54307 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Comt catechol-O-methyltransferase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000043
MGI:2178542 (MGI:3040120|PMID:11849292)		 UniProt
RGD		 PMID:11849292 GO_REF:0000043 MGI:3040120 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Dbh dopamine beta-hydroxylase IC RGD PMID:11521740 RGD:1625401 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Ddc dopa decarboxylase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Mtpn myotrophin IEP RGD PMID:12051753 RGD:625450 NCBI chr 4:64,159,273...64,186,686
Ensembl chr 4:64,157,641...64,186,724 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 IDA RGD PMID:6959650 RGD:2301075 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
G Sult1d1 sulfotransferase family 1D, member 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:20,441,135...20,476,341
Ensembl chr14:20,441,924...20,476,341 		JBrowse link
catecholamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:17194738 RGD:5131263 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904 		JBrowse link
G Ddc dopa decarboxylase involved_in TAS
IEA		 GO_REF:0000043 UniProt
RGD		 PMID:12047348 GO_REF:0000043, RGD:727571 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Hdc histidine decarboxylase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341 		JBrowse link
G Th tyrosine hydroxylase IDA RGD PMID:20025246 RGD:4139888 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
catecholamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase involved_in IBA
IEA
ISS
ISO		 PMID:21873635
GO_REF:0000107
GO_REF:0000024
(PMID:11559542), (PMID:15645182), (PMID:21846718)		 Ensembl
UniProt
RGD		 PMID:11559542 PMID:15645182 PMID:21846718 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Lrtomt leucine rich transmembrane and O-methyltransferase domain containing involved_in ISS
ISO
IBA		 GO_REF:0000024
(MGI:3799635|PMID:18794526)
PMID:21873635		 UniProt
RGD		 PMID:18794526 PMID:21873635 GO_REF:0000024 MGI:3799635, RGD:13792537 NCBI chr 1:156,266,655...156,268,704
Ensembl chr 1:156,266,655...156,268,704 		JBrowse link
G Maoa monoamine oxidase A NAS RGD PMID:12388421 RGD:629546 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593 		JBrowse link
dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1a angiotensin II receptor, type 1a IMP RGD PMID:20097214 RGD:6903884 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 IMP RGD PMID:20097214 RGD:6903884 NCBI chr  X:112,119,876...112,124,060
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit IEP RGD PMID:12438507 RGD:704388 NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 IDA RGD PMID:19818757 RGD:5143981 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Dao D-amino-acid oxidase involved_in ISO (PMID:17303072) RGD PMID:17303072 NCBI chr12:42,592,342...42,613,046
Ensembl chr12:42,592,343...42,612,741 		JBrowse link
G Ddc dopa decarboxylase involved_in IDA
IEA		 GO_REF:0000041 UniProt
RGD		 PMID:12703659 GO_REF:0000041, RGD:4139893 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Gch1 GTP cyclohydrolase 1 involved_in ISO (PMID:16338639) RGD PMID:16338639 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698 		JBrowse link
G Gpr37 G protein-coupled receptor 37 acts_upstream_of_or_within ISO MGI:3027995 (MGI:3046856|PMID:15218106) RGD PMID:15218106 MGI:3046856 NCBI chr 4:54,138,860...54,160,927
Ensembl chr 4:54,138,870...54,161,001 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:2429971 (MGI:1203924|PMID:9608532), (MGI:3767764|PMID:16782508)
GO_REF:0000107		 RGD
Ensembl		 PMID:9608532 PMID:16782508 GO_REF:0000107 MGI:1203924 MGI:3767764 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 acts_upstream_of_or_within ISO MGI:2386303 (MGI:2386819|PMID:9520487) RGD PMID:9520487 MGI:2386819 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Snca synuclein alpha acts_upstream_of_or_within ISO MGI:1888382 (MGI:1352916|PMID:10707987) RGD PMID:10707987 MGI:1352916 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3622848|PMID:16257223)		 UniProt
RGD		 PMID:16257223 GO_REF:0000024 MGI:3622848 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Th tyrosine hydroxylase involved_in ISO
IEA		 (PMID:12457228)
GO_REF:0000041		 RGD
UniProt		 PMID:12457228 GO_REF:0000041 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
dopamine biosynthetic process from tyrosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Th tyrosine hydroxylase acts_upstream_of_or_within
involved_in		 IDA
ISO
IMP
IBA		 MGI:1860450 (MGI:2386819|PMID:9520487), (MGI:72094|PMID:7715703), (MGI:77787|PMID:7592982)
PMID:11943812
PMID:21873635		 RGD PMID:7592982 PMID:7715703 PMID:9520487 PMID:2427363 PMID:11943812 More... MGI:2386819 MGI:72094 MGI:77787, RGD:1580046, RGD:5129111, RGD:13792537, RGD:5130972 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
dopamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase acts_upstream_of_or_within ISO (MGI:2386819|PMID:9520487) RGD PMID:9520487 MGI:2386819 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Dbh dopamine beta-hydroxylase involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA
ISS		 (PMID:3443096), (PMID:7961964)
(MGI:5787847|PMID:27148966), (MGI:72180|PMID:7715704)
MGI:1857556 (MGI:1332340|PMID:10051631)
PMID:21873635
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:3443096 PMID:7715704 PMID:7961964 PMID:10051631 PMID:27148966 More... GO_REF:0000024 GO_REF:0000107 MGI:1332340 MGI:5787847 MGI:72180, RGD:13792537 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Maoa monoamine oxidase A acts_upstream_of_or_within ISO (MGI:2386819|PMID:9520487) RGD PMID:9520487 MGI:2386819 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593 		JBrowse link
G Moxd1 monooxygenase, DBH-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:21,075,124...21,165,348
Ensembl chr 1:21,075,122...21,161,779 		JBrowse link
G Moxd2 monooxygenase, DBH-like 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:69,724,693...69,733,188
Ensembl chr 4:69,724,239...69,733,299 		JBrowse link
G Pde1b phosphodiesterase 1B involved_in
acts_upstream_of_positive_effect		 IEA
ISO		 GO_REF:0000107
MGI:3604470 (MGI:3769297|PMID:17559891)		 Ensembl
RGD		 PMID:17559891 GO_REF:0000107 MGI:3769297 NCBI chr 7:134,627,378...134,654,581
Ensembl chr 7:134,627,322...134,654,580 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 acts_upstream_of_or_within ISO MGI:2386303 (MGI:2386819|PMID:9520487) RGD PMID:9520487 MGI:2386819 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856098|MGI:1856466 (MGI:50550|PMID:1752214), (MGI:65000|PMID:8174230) RGD PMID:1752214 PMID:8174230 MGI:50550 MGI:65000 MGI:71923 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Comt catechol-O-methyltransferase involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:2178542 (MGI:3040120|PMID:11849292), (MGI:3834010|PMID:17881525), (MGI:5314492|PMID:22169008), (MGI:5510279|PMID:23863468), (MGI:5585563|PMID:24591155), (MGI:6274079|PMID:27388330), (MGI:6377798|PMID:19770404)
MGI:2178542|MGI:4830700 (MGI:4830461|PMID:19930170)		 RGD PMID:11849292 PMID:17881525 PMID:19770404 PMID:19930170 PMID:22169008 More... MGI:3040120 MGI:3834010 MGI:4830461 MGI:5314492 MGI:5510279 MGI:5585563 MGI:6274079 MGI:6377798, RGD:13792537 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 IDA RGD PMID:10945868 RGD:1599723 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Ddc dopa decarboxylase TAS RGD PMID:7567987 RGD:727686 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Drd2 dopamine receptor D2 acts_upstream_of_or_within ISO (MGI:68905|PMID:7925842) RGD PMID:7925842 MGI:68905 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Gnat2 G protein subunit alpha transducin 2 acts_upstream_of_or_within ISO MGI:3588845 (MGI:6416735|PMID:32049342) RGD PMID:32049342 MGI:6416735 NCBI chr 2:195,726,371...195,735,866
Ensembl chr 2:195,726,762...195,735,866 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1928285 (MGI:2384280|PMID:11160454)
GO_REF:0000107		 RGD
Ensembl		 PMID:11160454 GO_REF:0000107 MGI:2384280 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1857299 (MGI:1321418|PMID:9886073), (MGI:65825|PMID:7509865), (MGI:65928|PMID:1432691)
GO_REF:0000107		 RGD
Ensembl		 PMID:1432691 PMID:7509865 PMID:9886073 GO_REF:0000107 MGI:1321418 MGI:65825 MGI:65928 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154 		JBrowse link
G Lrtomt leucine rich transmembrane and O-methyltransferase domain containing involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:156,266,655...156,268,704
Ensembl chr 1:156,266,655...156,268,704 		JBrowse link
G Myo5a myosin VA IMP RGD PMID:29217155 RGD:42721980 NCBI chr 8:75,811,985...75,980,049
Ensembl chr 8:75,812,412...75,975,918 		JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 acts_upstream_of_or_within ISO MGI:3527173 (MGI:6150107|PMID:28327638) RGD PMID:28327638 MGI:6150107 NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846 		JBrowse link
G Npr1 natriuretic peptide receptor 1 IMP RGD PMID:15544851 RGD:1580153 NCBI chr 2:175,934,181...175,950,118
Ensembl chr 2:175,934,181...175,949,505 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 acts_upstream_of_or_within ISO MGI:2429971 (MGI:3529728|PMID:12385813) RGD PMID:12385813 MGI:3529728 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase acts_upstream_of_or_within
involved_in
NOT|acts_upstream_of_or_within		 ISO
IEA		 MGI:2678247 (MGI:2675710|PMID:12915482)
GO_REF:0000107
MGI:3055212 (MGI:3525458|PMID:15684050)		 RGD
Ensembl		 PMID:12915482 PMID:15684050 GO_REF:0000107 MGI:2675710 MGI:3525458 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Rnls renalase, FAD-dependent amine oxidase acts_upstream_of_or_within ISO MGI:5433853 (MGI:5433454|PMID:21178975) RGD PMID:21178975 MGI:5433454 NCBI chr 1:231,037,481...231,309,855
Ensembl chr 1:231,037,486...231,309,823 		JBrowse link
G Slc1a1 solute carrier family 1 member 1 involved_in ISO (MGI:5904876|PMID:28507136) RGD PMID:28507136 MGI:5904876 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402 		JBrowse link
G Snca synuclein alpha acts_upstream_of_or_within ISO MGI:1889011 (MGI:3057254|PMID:15465911) RGD PMID:15465911 MGI:3057254 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Sncaip synuclein, alpha interacting protein involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:14506261)		 ParkinsonsUK-UCL
RGD		 PMID:14506261 GO_REF:0000024 NCBI chr18:46,205,846...46,343,932
Ensembl chr18:46,207,152...46,343,929 		JBrowse link
G Sncb synuclein, beta acts_upstream_of_or_within ISO MGI:1277151 (MGI:3057254|PMID:15465911) RGD PMID:15465911 MGI:3057254 NCBI chr17:9,846,802...9,855,013
Ensembl chr17:9,846,802...9,855,012 		JBrowse link
G Spr sepiapterin reductase acts_upstream_of_or_within ISO MGI:3757641 (MGI:3722569|PMID:16532389) RGD PMID:16532389 MGI:3722569 NCBI chr 4:117,671,948...117,676,292
Ensembl chr 4:117,671,949...117,675,678 		JBrowse link
epinephrine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnmt phenylethanolamine-N-methyltransferase involved_in TAS
IEA
IDA
IC		 GO_REF:0000041 UniProt
RGD		 PMID:11514309 PMID:7914070 PMID:7503429 GO_REF:0000041, RGD:628457, RGD:4139902, RGD:4139901 NCBI chr10:83,383,019...83,386,557
Ensembl chr10:83,384,923...83,386,556 		JBrowse link
G Th tyrosine hydroxylase involved_in ISO (PMID:12457228) RGD PMID:12457228 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
epinephrine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856098|MGI:1856466 (MGI:50550|PMID:1752214) RGD PMID:1752214 MGI:50550 MGI:71923 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Rnls renalase, FAD-dependent amine oxidase acts_upstream_of_or_within ISO MGI:5433853 (MGI:5433454|PMID:21178975) RGD PMID:21178975 MGI:5433454 NCBI chr 1:231,037,481...231,309,855
Ensembl chr 1:231,037,486...231,309,823 		JBrowse link
negative regulation of catecholamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856098 (MGI:54307|PMID:17511) RGD PMID:17511 MGI:54307 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
negative regulation of dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase IMP RGD PMID:15190105 RGD:2289786 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C IMP RGD PMID:17018023 RGD:1625003 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Itgam integrin subunit alpha M involved_in ISO (MGI:3814938|PMID:18981141) RGD PMID:18981141 MGI:3814938 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Snca synuclein alpha involved_in IMP PMID:11943812 BHF-UCL PMID:11943812 RGD:5129111 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
norepinephrine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856097|MGI:1856098 (MGI:53801|PMID:4405722), (MGI:53940|PMID:4858102) RGD PMID:4405722 PMID:4858102 MGI:53801 MGI:53940 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Dbh dopamine beta-hydroxylase involved_in
acts_upstream_of_or_within		 TAS
ISO
ISS
IBA
IEA
IMP		 (MGI:5787847|PMID:27148966), (MGI:72180|PMID:7715704)
MGI:1857556 (MGI:1203930|PMID:9603211), (MGI:1332340|PMID:10051631)
(PMID:27148966)
GO_REF:0000024
PMID:21873635
GO_REF:0000041		 RGD
UniProt		 PMID:7715704 PMID:9603211 PMID:10051631 PMID:27148966 PMID:11914591 More... GO_REF:0000024 GO_REF:0000041 MGI:1203930 MGI:1332340 MGI:5787847 MGI:72180, RGD:727567, RGD:13792537, RGD:1625403 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Epas1 endothelial PAS domain protein 1 IMP RGD PMID:19457096 RGD:5128877 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO MGI:2153826 (MGI:1859081|PMID:10835639) RGD PMID:10835639 MGI:1859081 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in
acts_upstream_of_positive_effect		 IEA
ISO		 GO_REF:0000107
(MGI:4413411|PMID:19008477)		 Ensembl
RGD		 PMID:19008477 GO_REF:0000107 MGI:4413411 NCBI chr16:32,917,448...32,920,791
Ensembl chr16:32,917,823...32,919,891 		JBrowse link
G Insm1 INSM transcriptional repressor 1 involved_in ISO (MGI:3772428|PMID:18094025) RGD PMID:18094025 MGI:3772428 NCBI chr 3:133,640,030...133,642,963
Ensembl chr 3:133,639,580...133,643,003 		JBrowse link
G Kl Klotho IMP RGD PMID:20086041 RGD:10403068 NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080 		JBrowse link
G Moxd1 monooxygenase, DBH-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:21,075,124...21,165,348
Ensembl chr 1:21,075,122...21,161,779 		JBrowse link
G Moxd2 monooxygenase, DBH-like 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:69,724,693...69,733,188
Ensembl chr 4:69,724,239...69,733,299 		JBrowse link
G Th tyrosine hydroxylase involved_in ISO (PMID:12457228) RGD PMID:12457228 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
norepinephrine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b1 aldo-keto reductase family 1 member B1 IDA RGD PMID:10424772 RGD:8548769 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856102|MGI:1856466 (MGI:53851|PMID:4147174) RGD PMID:4147174 MGI:53851 MGI:71923 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Comt catechol-O-methyltransferase acts_upstream_of_or_within ISO MGI:2178542 (MGI:3040120|PMID:11849292), (MGI:5585563|PMID:24591155) RGD PMID:11849292 PMID:24591155 MGI:3040120 MGI:5585563 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Ednra endothelin receptor type A involved_in ISO
IEA		 MGI:2687362 (MGI:5608725|PMID:25197047)
GO_REF:0000107		 RGD
Ensembl		 PMID:25197047 GO_REF:0000107 MGI:5608725 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Epas1 endothelial PAS domain protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1861921 (MGI:1313089|PMID:9808618)		 Ensembl
RGD		 PMID:9808618 GO_REF:0000107 MGI:1313089 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Ly6e lymphocyte antigen 6 family member E acts_upstream_of_or_within ISO MGI:2429638 (MGI:2157257|PMID:11784869) RGD PMID:11784869 MGI:2157257 NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689 		JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase IDA RGD PMID:3945626 RGD:5130757 NCBI chr10:83,383,019...83,386,557
Ensembl chr10:83,384,923...83,386,556 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:3050230 (MGI:3047192|PMID:15249681)
GO_REF:0000107		 RGD
Ensembl		 PMID:15249681 GO_REF:0000107 MGI:3047192 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Rnf180 ring finger protein 180 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:5505713|PMID:23926250)		 RGD PMID:23926250 PMID:21873635 MGI:5505713, RGD:13792537 NCBI chr 2:36,330,285...36,511,168
Ensembl chr 2:36,330,292...36,512,614 		JBrowse link
G Rnls renalase, FAD-dependent amine oxidase acts_upstream_of_or_within ISO MGI:5433853 (MGI:5433454|PMID:21178975) RGD PMID:21178975 MGI:5433454 NCBI chr 1:231,037,481...231,309,855
Ensembl chr 1:231,037,486...231,309,823 		JBrowse link
G Rtl4 retrotransposon Gag like 4 acts_upstream_of_or_within ISO MGI:5789261 (MGI:5749620|PMID:26402067) RGD PMID:26402067 MGI:5749620 NCBI chr  X:108,231,052...108,641,768
Ensembl chr  X:108,633,651...108,640,050 		JBrowse link
G Spr sepiapterin reductase acts_upstream_of_or_within ISO MGI:3757641 (MGI:3722569|PMID:16532389) RGD PMID:16532389 MGI:3722569 NCBI chr 4:117,671,948...117,676,292
Ensembl chr 4:117,671,949...117,675,678 		JBrowse link
positive regulation of dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epas1 endothelial PAS domain protein 1 IMP RGD PMID:19457096 RGD:5128877 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:19703902)
GO_REF:0000107		 ParkinsonsUK-UCL
RGD
Ensembl		 PMID:19703902 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Vps35 VPS35 retromer complex component involved_in ISO (MGI:5694519|PMID:26203154) RGD PMID:26203154 MGI:5694519 NCBI chr19:21,765,771...21,801,620
Ensembl chr19:21,765,749...21,801,618 		JBrowse link
positive regulation of dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IMP RGD PMID:11239920 RGD:10047061 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835 		JBrowse link
G Gpr37 G protein-coupled receptor 37 acts_upstream_of_or_within ISO MGI:3027995 (MGI:3046856|PMID:15218106) RGD PMID:15218106 MGI:3046856 NCBI chr 4:54,138,860...54,160,927
Ensembl chr 4:54,138,870...54,161,001 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 involved_in ISO
IEA		 (PMID:8643611)
GO_REF:0000107		 RGD
Ensembl		 PMID:8643611 GO_REF:0000107 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154 		JBrowse link
G Maob monoamine oxidase B IMP RGD PMID:12175458 RGD:2316765 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003 		JBrowse link
G Npy neuropeptide Y IDA RGD PMID:19579268 RGD:10448966 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
regulation of catecholamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vhl von Hippel-Lindau tumor suppressor IMP RGD PMID:11912140 RGD:619592 NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377 		JBrowse link
regulation of dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member involved_in ISS
ISO		 GO_REF:0000024
(MGI:6827320|PMID:26711020)		 UniProt
RGD		 PMID:26711020 GO_REF:0000024 MGI:6827320 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
regulation of dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of_or_within ISO MGI:1926253 (MGI:3618656|PMID:11282258) RGD PMID:11282258 MGI:3618656 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Drd1 dopamine receptor D1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857158 (MGI:2136539|PMID:11438590)		 Ensembl
RGD		 PMID:11438590 GO_REF:0000107 MGI:2136539 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd4 dopamine receptor D4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2178631 (MGI:1097029|PMID:9323127)		 Ensembl
RGD		 PMID:9323127 GO_REF:0000107 MGI:1097029 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A involved_in ISO
ISS		 (MGI:1927024|PMID:11080193)
GO_REF:0000024		 RGD
UniProt		 PMID:11080193 GO_REF:0000024 MGI:1927024 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:2671567|PMID:12915123)		 Ensembl
RGD		 PMID:12915123 GO_REF:0000107 MGI:2671567 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877 		JBrowse link
G Pnkd PNKD metallo-beta-lactamase domain containing acts_upstream_of_or_within ISO MGI:5006973 (MGI:5466578|PMID:22214848) RGD PMID:22214848 MGI:5466578 NCBI chr 9:75,868,620...75,937,126
Ensembl chr 9:75,867,468...75,937,124 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA		 (PMID:22314364)
GO_REF:0000107		 RGD
Ensembl		 PMID:22314364 GO_REF:0000107 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 acts_upstream_of_or_within ISO MGI:2386303 (MGI:2386819|PMID:9520487), (MGI:894559|PMID:9247269) RGD PMID:9247269 PMID:9520487 MGI:2386819 MGI:894559 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Tacr3 tachykinin receptor 3 IDA RGD PMID:8574643 RGD:2305963 NCBI chr 2:223,266,536...223,363,791
Ensembl chr 2:223,266,536...223,363,791 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19553
    metabolic process 11538
      nitrogen compound metabolic process 9399
        organonitrogen compound metabolic process 5645
          amine metabolic process 130
            biogenic amine metabolic process 106
              catecholamine metabolic process 65
                catecholamine biosynthetic process + 28
                catecholamine catabolic process + 8
                dopamine metabolic process + 49
                epinephrine metabolic process + 4
                negative regulation of catecholamine metabolic process + 5
                norepinephrine metabolic process + 20
                positive regulation of catecholamine metabolic process + 8
                regulation of catecholamine metabolic process + 24
paths to the root