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ONTOLOGY REPORT - ANNOTATIONS

Term:catecholamine metabolic process
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Accession:GO:0006584 term browser browse the term
Definition:The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.
Synonyms:exact_synonym: catecholamine metabolism


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catecholamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of
acts_upstream_of_or_within		 ISO MGI:1856098 (PMID:17511) RGD PMID:17511 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Comt catechol-O-methyltransferase acts_upstream_of_or_within ISO MGI:2178542 (PMID:11849292) RGD PMID:11849292 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Dbh dopamine beta-hydroxylase IC RGD PMID:11521740 RGD:1625401 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Ddc dopa decarboxylase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Maoa monoamine oxidase A involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593 		JBrowse link
G Mtpn myotrophin IEP RGD PMID:12051753 RGD:625450 NCBI chr 4:64,159,273...64,186,686
Ensembl chr 4:64,157,641...64,186,724 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 IDA RGD PMID:6959650 RGD:2301075 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
G Sult1d1 sulfotransferase family 1D, member 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:20,441,135...20,476,341
Ensembl chr14:20,441,924...20,476,341 		JBrowse link
catecholamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:17194738 RGD:5131263 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904 		JBrowse link
G Ddc dopa decarboxylase involved_in TAS
IEA		 GO_REF:0000043 UniProt
RGD		 PMID:12047348 GO_REF:0000043, RGD:727571 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Hdc histidine decarboxylase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341 		JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:83,383,019...83,386,557
Ensembl chr10:83,384,923...83,386,556 		JBrowse link
G Th tyrosine hydroxylase IDA RGD PMID:20025246 RGD:4139888 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
catecholamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase involved_in ISO
IEA
IBA
ISS		 (PMID:11559542), (PMID:15645182), (PMID:21846718)
GO_REF:0000104
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
UniProt
GO_Central
Ensembl		 PMID:11559542 PMID:15645182 PMID:21846718 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Lrtomt leucine rich transmembrane and O-methyltransferase domain containing involved_in ISS
ISO
IBA		 GO_REF:0000024
(PMID:18794526)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:18794526 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:156,266,655...156,268,704
Ensembl chr 1:156,266,655...156,268,704 		JBrowse link
G Maoa monoamine oxidase A NAS RGD PMID:12388421 RGD:629546 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593 		JBrowse link
dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1a angiotensin II receptor, type 1a IMP RGD PMID:20097214 RGD:6903884 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 IMP RGD PMID:20097214 RGD:6903884 NCBI chr  X:112,119,876...112,124,060
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit IEP RGD PMID:12438507 RGD:704388 NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 IDA RGD PMID:19818757 RGD:5143981 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Dao D-amino-acid oxidase involved_in ISO
ISS		 (PMID:17303072)
(PMID:17042912)
GO_REF:0000024		 RGD
UniProt		 PMID:17042912 PMID:17303072 GO_REF:0000024 NCBI chr12:42,592,342...42,613,046
Ensembl chr12:42,592,343...42,612,741 		JBrowse link
G Ddc dopa decarboxylase involved_in IDA
ISO
IEA		 (PMID:19703902)
GO_REF:0000107
GO_REF:0000041		 RGD
Ensembl
UniProt		 PMID:19703902 PMID:12703659 GO_REF:0000041 GO_REF:0000107, RGD:4139893 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Gch1 GTP cyclohydrolase 1 involved_in ISO (PMID:16338639) RGD PMID:16338639 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698 		JBrowse link
G Gpr37 G protein-coupled receptor 37 acts_upstream_of_or_within ISO MGI:3027995 (PMID:15218106) RGD PMID:15218106 NCBI chr 4:54,138,860...54,160,927
Ensembl chr 4:54,138,870...54,161,001 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2429971 (PMID:16782508), (PMID:9608532)		 Ensembl
RGD		 PMID:9608532 PMID:16782508 GO_REF:0000107 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 acts_upstream_of_or_within ISO MGI:2386303 (PMID:9520487) RGD PMID:9520487 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Snca synuclein alpha acts_upstream_of_or_within ISO MGI:1888382 (PMID:10707987) RGD PMID:10707987 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16257223)		 UniProt
RGD		 PMID:16257223 GO_REF:0000024 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Th tyrosine hydroxylase involved_in IEA
ISO		 GO_REF:0000041
(PMID:12457228), (PMID:19703902)		 UniProt
RGD		 PMID:12457228 PMID:19703902 GO_REF:0000041 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
dopamine biosynthetic process from tyrosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Th tyrosine hydroxylase acts_upstream_of_or_within
involved_in		 IDA
ISO
IBA
IMP		 MGI:1860450 (PMID:7592982), (PMID:7715703), (PMID:9520487)
GO_REF:0000033
PMID:11943812		 RGD
GO_Central		 PMID:7592982 PMID:7715703 PMID:9520487 PMID:2427363 PMID:11943812 More... GO_REF:0000033, RGD:1580046, RGD:5129111, RGD:5130972 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
dopamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase acts_upstream_of_or_within ISO (PMID:9520487) RGD PMID:9520487 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Dbh dopamine beta-hydroxylase involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA
ISS		 (PMID:3443096), (PMID:7961964)
(PMID:27148966), (PMID:7715704)
MGI:1857556 (PMID:10051631)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
UniProt		 PMID:3443096 PMID:7715704 PMID:7961964 PMID:10051631 PMID:27148966 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Maoa monoamine oxidase A acts_upstream_of_or_within ISO (PMID:9520487) RGD PMID:9520487 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593 		JBrowse link
G Moxd1 monooxygenase, DBH-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:21,075,124...21,165,348
Ensembl chr 1:21,075,122...21,161,779 		JBrowse link
G Moxd2 monooxygenase, DBH-like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:69,724,693...69,733,188
Ensembl chr 4:69,724,239...69,733,299 		JBrowse link
G Pde1b phosphodiesterase 1B acts_upstream_of_positive_effect ISO MGI:3604470 (PMID:17559891) RGD PMID:17559891 NCBI chr 7:134,627,378...134,654,581
Ensembl chr 7:134,627,322...134,654,580 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 acts_upstream_of_or_within ISO MGI:2386303 (PMID:9520487) RGD PMID:9520487 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856098|MGI:1856466 (PMID:1752214), (PMID:8174230) RGD PMID:1752214 PMID:8174230 MGI:71923 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Comt catechol-O-methyltransferase involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000104
MGI:2178542 (PMID:11849292), (PMID:17881525), (PMID:19770404), (PMID:22169008), (PMID:23863468), (PMID:24591155), (PMID:27388330)		 GO_Central
UniProt
RGD		 PMID:11849292 PMID:17881525 PMID:19770404 PMID:22169008 PMID:23863468 More... GO_REF:0000033 GO_REF:0000104 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 IDA RGD PMID:10945868 RGD:1599723 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Ddc dopa decarboxylase TAS RGD PMID:7567987 RGD:727686 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Drd2 dopamine receptor D2 acts_upstream_of_or_within ISO (PMID:7925842) RGD PMID:7925842 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Gnat2 G protein subunit alpha transducin 2 acts_upstream_of_or_within ISO MGI:3588845 (PMID:32049342) RGD PMID:32049342 NCBI chr 2:195,726,371...195,735,866
Ensembl chr 2:195,726,762...195,735,866 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1928285 (PMID:11160454)		 Ensembl
RGD		 PMID:11160454 GO_REF:0000107 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857299 (PMID:1432691), (PMID:7509865), (PMID:9886073)		 Ensembl
RGD		 PMID:1432691 PMID:7509865 PMID:9886073 GO_REF:0000107 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154 		JBrowse link
G Lrtomt leucine rich transmembrane and O-methyltransferase domain containing involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:156,266,655...156,268,704
Ensembl chr 1:156,266,655...156,268,704 		JBrowse link
G Myo5a myosin VA IMP RGD PMID:29217155 RGD:42721980 NCBI chr 8:75,811,985...75,980,049
Ensembl chr 8:75,812,412...75,975,918 		JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 acts_upstream_of_or_within ISO MGI:3527173 (PMID:28327638) RGD PMID:28327638 NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846 		JBrowse link
G Npr1 natriuretic peptide receptor 1 IMP RGD PMID:15544851 RGD:1580153 NCBI chr 2:175,934,181...175,950,118
Ensembl chr 2:175,934,181...175,949,505 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 acts_upstream_of_or_within ISO MGI:2429971 (PMID:12385813) RGD PMID:12385813 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in
acts_upstream_of_or_within
NOT|acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2678247 (PMID:12915482)
MGI:3055212 (PMID:15684050)		 Ensembl
RGD		 PMID:12915482 PMID:15684050 GO_REF:0000107 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Rnls renalase, FAD-dependent amine oxidase acts_upstream_of_or_within ISO MGI:5433853 (PMID:21178975) RGD PMID:21178975 NCBI chr 1:231,037,481...231,309,855
Ensembl chr 1:231,037,486...231,309,823 		JBrowse link
G Slc1a1 solute carrier family 1 member 1 involved_in ISO (PMID:28507136) RGD PMID:28507136 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402 		JBrowse link
G Snca synuclein alpha acts_upstream_of_or_within ISO MGI:1889011 (PMID:15465911) RGD PMID:15465911 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Sncaip synuclein, alpha interacting protein involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:14506261)		 ParkinsonsUK-UCL
RGD		 PMID:14506261 GO_REF:0000024 NCBI chr18:46,205,846...46,343,932
Ensembl chr18:46,207,152...46,343,929 		JBrowse link
G Sncb synuclein, beta acts_upstream_of_or_within ISO MGI:1277151 (PMID:15465911) RGD PMID:15465911 NCBI chr17:9,846,802...9,855,013
Ensembl chr17:9,846,802...9,855,012 		JBrowse link
G Spr sepiapterin reductase acts_upstream_of_or_within ISO MGI:3757641 (PMID:16532389) RGD PMID:16532389 NCBI chr 4:117,671,948...117,676,292
Ensembl chr 4:117,671,949...117,675,678 		JBrowse link
epinephrine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnmt phenylethanolamine-N-methyltransferase involved_in TAS
IEA
IDA
IC		 GO_REF:0000041 UniProt
RGD		 PMID:11514309 PMID:7914070 PMID:7503429 GO_REF:0000041, RGD:628457, RGD:4139902, RGD:4139901 NCBI chr10:83,383,019...83,386,557
Ensembl chr10:83,384,923...83,386,556 		JBrowse link
G Th tyrosine hydroxylase involved_in ISO (PMID:12457228) RGD PMID:12457228 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
epinephrine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856098|MGI:1856466 (PMID:1752214) RGD PMID:1752214 MGI:71923 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Rnls renalase, FAD-dependent amine oxidase acts_upstream_of_or_within ISO MGI:5433853 (PMID:21178975) RGD PMID:21178975 NCBI chr 1:231,037,481...231,309,855
Ensembl chr 1:231,037,486...231,309,823 		JBrowse link
negative regulation of catecholamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856098 (PMID:17511) RGD PMID:17511 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Nt5dc2 5'-nucleotidase domain containing 2 involved_in IMP PMID:31279527 UniProt PMID:31279527 RGD:408345212 NCBI chr16:6,322,485...6,330,538
Ensembl chr16:6,322,236...6,330,537 		JBrowse link
negative regulation of dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nt5dc2 5'-nucleotidase domain containing 2 involved_in IMP PMID:31279527 UniProt PMID:31279527 RGD:408345212 NCBI chr16:6,322,485...6,330,538
Ensembl chr16:6,322,236...6,330,537 		JBrowse link
negative regulation of dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase IMP RGD PMID:15190105 RGD:2289786 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C IMP RGD PMID:17018023 RGD:1625003 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Itgam integrin subunit alpha M involved_in ISO (PMID:18981141) RGD PMID:18981141 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Snca synuclein alpha involved_in IMP PMID:11943812 BHF-UCL PMID:11943812 RGD:5129111 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
norepinephrine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856097|MGI:1856098 (PMID:4405722), (PMID:4858102) RGD PMID:4405722 PMID:4858102 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Dbh dopamine beta-hydroxylase involved_in
acts_upstream_of_or_within		 TAS
ISO
IBA
ISS
IEA
IMP		 (PMID:27148966), (PMID:7715704)
MGI:1857556 (PMID:10051631), (PMID:9603211)
GO_REF:0000033
GO_REF:0000024
GO_REF:0000041		 RGD
GO_Central
UniProt		 PMID:7715704 PMID:9603211 PMID:10051631 PMID:27148966 PMID:11914591 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000041, RGD:727567, RGD:1625403 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Epas1 endothelial PAS domain protein 1 IMP RGD PMID:19457096 RGD:5128877 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO MGI:2153826 (PMID:10835639) RGD PMID:10835639 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in
acts_upstream_of_positive_effect		 IEA
ISO		 GO_REF:0000107
(PMID:19008477)		 Ensembl
RGD		 PMID:19008477 GO_REF:0000107 NCBI chr16:32,917,448...32,920,791
Ensembl chr16:32,917,823...32,919,891 		JBrowse link
G Insm1 INSM transcriptional repressor 1 involved_in ISO (PMID:18094025) RGD PMID:18094025 NCBI chr 3:133,640,030...133,642,963
Ensembl chr 3:133,639,580...133,643,003 		JBrowse link
G Kl Klotho IMP RGD PMID:20086041 RGD:10403068 NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080 		JBrowse link
G Moxd1 monooxygenase, DBH-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:21,075,124...21,165,348
Ensembl chr 1:21,075,122...21,161,779 		JBrowse link
G Moxd2 monooxygenase, DBH-like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:69,724,693...69,733,188
Ensembl chr 4:69,724,239...69,733,299 		JBrowse link
G Th tyrosine hydroxylase involved_in ISO (PMID:12457228) RGD PMID:12457228 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
norepinephrine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b1 aldo-keto reductase family 1 member B1 IDA RGD PMID:10424772 RGD:8548769 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856102|MGI:1856466 (PMID:4147174) RGD PMID:4147174 MGI:71923 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Comt catechol-O-methyltransferase acts_upstream_of_or_within ISO MGI:2178542 (PMID:11849292), (PMID:24591155) RGD PMID:11849292 PMID:24591155 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Ednra endothelin receptor type A involved_in IEA
ISO		 GO_REF:0000107
MGI:2687362 (PMID:25197047)		 Ensembl
RGD		 PMID:25197047 GO_REF:0000107 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Epas1 endothelial PAS domain protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1861921 (PMID:9808618)		 Ensembl
RGD		 PMID:9808618 GO_REF:0000107 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Ly6e lymphocyte antigen 6 family member E acts_upstream_of_or_within ISO MGI:2429638 (PMID:11784869) RGD PMID:11784869 NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689 		JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase IDA RGD PMID:3945626 RGD:5130757 NCBI chr10:83,383,019...83,386,557
Ensembl chr10:83,384,923...83,386,556 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3050230 (PMID:15249681)		 Ensembl
RGD		 PMID:15249681 GO_REF:0000107 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Rnf180 ring finger protein 180 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:23926250)		 GO_Central
RGD		 PMID:23926250 GO_REF:0000033 NCBI chr 2:36,330,285...36,511,168
Ensembl chr 2:36,330,292...36,512,614 		JBrowse link
G Rnls renalase, FAD-dependent amine oxidase acts_upstream_of_or_within ISO MGI:5433853 (PMID:21178975) RGD PMID:21178975 NCBI chr 1:231,037,481...231,309,855
Ensembl chr 1:231,037,486...231,309,823 		JBrowse link
G Rtl4 retrotransposon Gag like 4 acts_upstream_of_or_within ISO MGI:5789261 (PMID:26402067) RGD PMID:26402067 NCBI chr  X:108,231,052...108,641,768
Ensembl chr  X:108,633,651...108,640,050 		JBrowse link
G Slitrk1 SLIT and NTRK-like family, member 1 acts_upstream_of_or_within ISO (PMID:36085162) RGD PMID:36085162 NCBI chr15:85,723,252...85,727,290
Ensembl chr15:85,724,475...85,727,509 		JBrowse link
G Spr sepiapterin reductase acts_upstream_of_or_within ISO MGI:3757641 (PMID:16532389) RGD PMID:16532389 NCBI chr 4:117,671,948...117,676,292
Ensembl chr 4:117,671,949...117,675,678 		JBrowse link
positive regulation of dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epas1 endothelial PAS domain protein 1 IMP RGD PMID:19457096 RGD:5128877 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISS
ISO		 GO_REF:0000024
(PMID:19703902)		 ParkinsonsUK-UCL
RGD		 PMID:19703902 GO_REF:0000024 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Vps35 VPS35 retromer complex component involved_in ISO (PMID:26203154) RGD PMID:26203154 NCBI chr19:21,765,771...21,801,620
Ensembl chr19:21,765,749...21,801,618 		JBrowse link
positive regulation of dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IMP RGD PMID:11239920 RGD:10047061 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835 		JBrowse link
G Gpr37 G protein-coupled receptor 37 acts_upstream_of_or_within ISO MGI:3027995 (PMID:15218106) RGD PMID:15218106 NCBI chr 4:54,138,860...54,160,927
Ensembl chr 4:54,138,870...54,161,001 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 involved_in ISO
IEA		 (PMID:8643611)
GO_REF:0000107		 RGD
Ensembl		 PMID:8643611 GO_REF:0000107 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154 		JBrowse link
G Maob monoamine oxidase B IMP RGD PMID:12175458 RGD:2316765 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003 		JBrowse link
G Npy neuropeptide Y IDA RGD PMID:19579268 RGD:10448966 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
regulation of catecholamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vhl von Hippel-Lindau tumor suppressor IMP RGD PMID:11912140 RGD:619592 NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377 		JBrowse link
regulation of dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member involved_in ISS
ISO		 GO_REF:0000024
(PMID:26711020)		 UniProt
RGD		 PMID:26711020 GO_REF:0000024 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
regulation of dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of_or_within ISO MGI:1926253 (PMID:11282258) RGD PMID:11282258 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Drd1 dopamine receptor D1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857158 (PMID:11438590)		 Ensembl
RGD		 PMID:11438590 GO_REF:0000107 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd4 dopamine receptor D4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2178631 (PMID:9323127)		 Ensembl
RGD		 PMID:9323127 GO_REF:0000107 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A involved_in ISS
ISO		 GO_REF:0000024
(PMID:11080193)		 UniProt
RGD		 PMID:11080193 GO_REF:0000024 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:12915123)		 Ensembl
RGD		 PMID:12915123 GO_REF:0000107 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877 		JBrowse link
G Pnkd PNKD metallo-beta-lactamase domain containing acts_upstream_of_or_within ISO MGI:5006973 (PMID:22214848) RGD PMID:22214848 NCBI chr 9:75,868,620...75,937,126
Ensembl chr 9:75,867,468...75,937,124 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA		 (PMID:22314364)
GO_REF:0000107		 RGD
Ensembl		 PMID:22314364 GO_REF:0000107 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 acts_upstream_of_or_within ISO MGI:2386303 (PMID:9247269), (PMID:9520487) RGD PMID:9247269 PMID:9520487 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Tacr3 tachykinin receptor 3 IDA RGD PMID:8574643 RGD:2305963 NCBI chr 2:223,266,536...223,363,791
Ensembl chr 2:223,266,536...223,363,791 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20075
    cellular process 19154
      metabolic process 11953
        amine metabolic process 123
          biogenic amine metabolic process 108
            catecholamine metabolic process 67
              catecholamine biosynthetic process + 29
              catecholamine catabolic process + 8
              dopamine metabolic process + 50
              epinephrine metabolic process + 4
              negative regulation of catecholamine metabolic process + 6
              norepinephrine metabolic process + 21
              positive regulation of catecholamine metabolic process + 8
              regulation of catecholamine metabolic process + 25
Path 2
Term Annotations click to browse term
  biological_process 20075
    cellular process 19154
      metabolic process 11953
        organic hydroxy compound metabolic process 585
          phenol-containing compound metabolic process 137
            catechol-containing compound metabolic process 67
              catecholamine metabolic process 67
                catecholamine biosynthetic process + 29
                catecholamine catabolic process + 8
                dopamine metabolic process + 50
                epinephrine metabolic process + 4
                negative regulation of catecholamine metabolic process + 6
                norepinephrine metabolic process + 21
                positive regulation of catecholamine metabolic process + 8
                regulation of catecholamine metabolic process + 25
paths to the root