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ONTOLOGY REPORT - ANNOTATIONS


Term:amino-acid betaine metabolic process
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Accession:GO:0006577 term browser browse the term
Definition:The chemical reactions and pathways involving any betaine, the N-trimethyl derivative of an amino acid.
Synonyms:exact_synonym: betaine metabolic process;   betaine metabolism


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amino-acid betaine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase involved_in IEA
ISO
GO_REF:0000107
(PMID:18230605)
Ensembl
RGD
PMID:18230605 GO_REF:0000107 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 NOT|involved_in ISO (PMID:18230605) RGD PMID:18230605 NCBI chr 2:24,895,525...24,912,475
Ensembl chr 2:24,895,533...24,912,475
JBrowse link
amino-acid betaine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhmt betaine-homocysteine S-methyltransferase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
JBrowse link
G Dmgdh dimethylglycine dehydrogenase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 2:24,912,600...24,987,533
Ensembl chr 2:24,912,578...24,987,528
JBrowse link
carnitine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadm acyl-CoA dehydrogenase medium chain involved_in ISO
IEA
(PMID:16972171)
GO_REF:0000107
RGD
Ensembl
PMID:16972171 GO_REF:0000107 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
JBrowse link
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 involved_in TAS
IEA
GO_REF:0000041 UniProt PMID:10702312 GO_REF:0000041, RGD:68317 NCBI chr13:79,505,738...79,522,539
Ensembl chr13:79,505,695...79,540,568
JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 involved_in TAS
ISS
IBA
ISO
IEA
PMID:9753662
PMID:21873635
GO_REF:0000024
(PMID:20599753), (PMID:9753662)
GO_REF:0000041
UniProt
RGD
PMID:9753662 PMID:20599753 PMID:10526231 PMID:9753662 PMID:21873635 GO_REF:0000024 GO_REF:0000041, RGD:632240, RGD:8554503, RGD:13792537 NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458
JBrowse link
G Tmlhe trimethyllysine hydroxylase, epsilon involved_in
acts_upstream_of_or_within
TAS
ISO
ISS
IBA
IEA
(PMID:23092983)
(PMID:15754339)
GO_REF:0000024
PMID:21873635
GO_REF:0000041
(MGI:2183690|PMID:12121276)
RGD
UniProt
PMID:12121276 PMID:15754339 PMID:23092983 PMID:11431483 PMID:21873635 GO_REF:0000024 GO_REF:0000041 MGI:2183690, RGD:70558, RGD:13792537 NCBI chr20:91,234...138,942
Ensembl chr20:91,272...140,386
JBrowse link
carnitine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadl acyl-CoA dehydrogenase, long chain involved_in ISO (MGI:1321427|PMID:9861014) RGD PMID:9861014 MGI:1321427 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
JBrowse link
carnitine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadm acyl-CoA dehydrogenase medium chain acts_upstream_of_or_within ISO MGI:3692446 (MGI:3692159|PMID:16121256) RGD PMID:16121256 MGI:3692159 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
JBrowse link
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 acts_upstream_of_or_within ISO (MGI:1861370|PMID:10702312) RGD PMID:10702312 MGI:1861370 NCBI chr13:79,505,738...79,522,539
Ensembl chr13:79,505,695...79,540,568
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A involved_in TAS
IDA
IBA
ISO
PMID:21990363
PMID:21873635
(PMID:11350182)
RGD PMID:11350182 PMID:12826662 PMID:21990363 PMID:21873635 RGD:1298786, RGD:8554544, RGD:13792537 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404
JBrowse link
G Cpt1c carnitine palmitoyltransferase 1c involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:18192268 PMID:21873635 RGD:2317579, RGD:13792537 NCBI chr 1:95,442,814...95,457,347
Ensembl chr 1:95,442,817...95,457,342
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 involved_in ISO
IEA
ISS
(PMID:20538056)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:20538056 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
JBrowse link
G Crot carnitine O-octanoyltransferase involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:5546000|PMID:15492013)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:15492013 GO_REF:0000024 GO_REF:0000107 MGI:5546000 NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109
JBrowse link
G Por cytochrome p450 oxidoreductase IEP RGD PMID:16616465 RGD:4889829 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Slc22a4 solute carrier family 22 member 4 acts_upstream_of_or_within ISO UniProtKB:Q9H015 (MGI:1352952|PMID:10655497) RGD PMID:10655497 MGI:1352952 NCBI chr10:38,133,333...38,179,932 JBrowse link
G Slc22a5 solute carrier family 22 member 5 acts_upstream_of_or_within ISO MGI:1856926 (MGI:3606365|PMID:15240869), (MGI:3692809|PMID:17027329), (MGI:61916|PMID:8325377), (MGI:67915|PMID:7914432), (MGI:78309|PMID:1996978) RGD PMID:1996978 PMID:7914432 PMID:8325377 PMID:15240869 PMID:17027329 MGI:3606365 MGI:3692809 MGI:61916 MGI:67915 MGI:78309 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
JBrowse link
carnitine metabolic process, CoA-linked term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadl acyl-CoA dehydrogenase, long chain involved_in IBA
ISO
PMID:21873635
(MGI:1321427|PMID:9861014)
RGD PMID:9861014 PMID:21873635 MGI:1321427, RGD:13792537 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain involved_in ISO
IEA
(PMID:16972171)
GO_REF:0000107
(MGI:4412440|PMID:18459129)
RGD
Ensembl
PMID:16972171 PMID:18459129 GO_REF:0000107 MGI:4412440 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
JBrowse link
G Crat carnitine O-acetyltransferase involved_in ISO
ISS
IEA
IBA
(PMID:15099582), (PMID:23485643), (PMID:2351134)
GO_REF:0000024
GO_REF:0000107
PMID:21873635
RGD
UniProt
Ensembl
PMID:2351134 PMID:15099582 PMID:23485643 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255
JBrowse link
glycine betaine biosynthetic process from choline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh7a1 aldehyde dehydrogenase 7 family, member A1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr18:50,003,242...50,042,193
Ensembl chr18:50,009,934...50,042,193
JBrowse link
G Chdh choline dehydrogenase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr16:5,194,269...5,225,541
Ensembl chr16:5,194,269...5,225,537
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11797
      cellular metabolic process 10717
        cellular nitrogen compound metabolic process 6561
          amino-acid betaine metabolic process 19
            N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process + 0
            amino-acid betaine biosynthetic process + 6
            amino-acid betaine catabolic process + 3
            carnitine metabolic process + 14
            ergothioneine metabolic process + 0
            glycine betaine metabolic process + 2
            selenoneine metabolic process + 0
            stachydrine metabolic process + 0
Path 2
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11797
      organic substance metabolic process 11337
        organonitrogen compound metabolic process 6802
          cellular modified amino acid metabolic process 202
            amino-acid betaine metabolic process 19
              N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process + 0
              amino-acid betaine biosynthetic process + 6
              amino-acid betaine catabolic process + 3
              carnitine metabolic process + 14
              ergothioneine metabolic process + 0
              glycine betaine metabolic process + 2
              selenoneine metabolic process + 0
              stachydrine metabolic process + 0
paths to the root