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ONTOLOGY REPORT - ANNOTATIONS


Term:tyrosine metabolic process
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Accession:GO:0006570 term browser browse the term
Definition:The chemical reactions and pathways involving tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid.
Synonyms:exact_synonym: tyrosine metabolism
 xref: UM-BBD_pathwayID:tyr;   Wikipedia:Tyrosine



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tyrosine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856102 (MGI:53851|PMID:4147174) RGD PMID:4147174 MGI:53851 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G Hgd homogentisate 1, 2-dioxygenase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr11:63,086,750...63,138,325
Ensembl chr11:63,086,752...63,138,323
JBrowse link
G Iyd iodotyrosine deiodinase involved_in ISO
ISS
IBA
(PMID:25395621)
GO_REF:0000024
PMID:21873635
RGD
UniProt
PMID:25395621 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
JBrowse link
G Thap4 THAP domain containing 4 involved_in ISO
ISS
(PMID:30524950)
GO_REF:0000024
RGD
UniProt
PMID:30524950 GO_REF:0000024 NCBI chr 9:94,242,581...94,282,312
Ensembl chr 9:94,242,581...94,282,306
JBrowse link
G Ttc36 tetratricopeptide repeat domain 36 acts_upstream_of_or_within ISO MGI:5588394 (MGI:6362140|PMID:31537781) RGD PMID:31537781 MGI:6362140 NCBI chr 8:45,112,737...45,116,345 JBrowse link
dopamine biosynthetic process from tyrosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Th tyrosine hydroxylase acts_upstream_of_or_within
involved_in
IDA
ISO
IMP
IBA
MGI:1860450 (MGI:2386819|PMID:9520487), (MGI:72094|PMID:7715703), (MGI:77787|PMID:7592982)
PMID:11943812
PMID:21873635
RGD PMID:7592982 PMID:7715703 PMID:9520487 PMID:2427363 PMID:11943812 More... MGI:2386819 MGI:72094 MGI:77787, RGD:1580046, RGD:5129111, RGD:13792537, RGD:5130972 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
melanin biosynthetic process from tyrosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dct dopachrome tautomerase involved_in ISO (MGI:3690794|PMID:2169885) RGD PMID:2169885 MGI:3690794 NCBI chr15:95,062,006...95,100,863
Ensembl chr15:95,062,003...95,100,836
JBrowse link
tyrosine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pah phenylalanine hydroxylase involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:16953590 PMID:21873635 RGD:1601531, RGD:13792537 NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130
JBrowse link
tyrosine biosynthetic process, by oxidation of phenylalanine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pah phenylalanine hydroxylase involved_in IDA
IEA
GO_REF:0000108 GOC
RGD
PMID:10839989 GO_REF:0000108, RGD:1601535 NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130
JBrowse link
G Pcbd1 pterin-4 alpha-carbinolamine dehydratase 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr20:29,037,545...29,044,322
Ensembl chr20:28,953,864...29,044,292
Ensembl chr20:28,953,864...29,044,292
JBrowse link
G Pcbd2 pterin-4 alpha-carbinolamine dehydratase 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr17:8,845,161...8,896,343 JBrowse link
tyrosine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fah fumarylacetoacetate hydrolase involved_in IEA
IBA
GO_REF:0000104
PMID:21873635
UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 1:138,548,830...138,571,599
Ensembl chr 1:138,548,834...138,571,505
JBrowse link
G Gstz1 glutathione S-transferase zeta 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284
JBrowse link
G Hpd 4-hydroxyphenylpyruvate dioxygenase acts_upstream_of_or_within
involved_in
TAS
ISO
IBA
IDA
(PMID:31537781)
PMID:21873635
PMID:8814303
RGD PMID:31537781 PMID:12867153 PMID:21873635 PMID:8814303 RGD:632936, RGD:13792537, RGD:8554707 NCBI chr12:33,381,397...33,392,750
Ensembl chr12:33,381,231...33,392,766
JBrowse link
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:17356132) RGD PMID:17356132 NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562
JBrowse link
G Tat tyrosine aminotransferase involved_in ISO
ISS
(PMID:7999802)
(MGI:5430853|PMID:21153519)
GO_REF:0000024
RGD
UniProt
PMID:7999802 PMID:21153519 GO_REF:0000024 MGI:5430853 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19390
    metabolic process 11736
      organic substance metabolic process 11278
        organic cyclic compound metabolic process 5819
          aromatic amino acid family metabolic process 31
            tyrosine metabolic process 15
              D-tyrosine metabolic process + 0
              dopamine biosynthetic process from tyrosine 1
              melanin biosynthetic process from tyrosine 1
              tyrosine biosynthetic process + 3
              tyrosine catabolic process + 5
              ubiquinone biosynthetic process from tyrosine 0
Path 2
Term Annotations click to browse term
  biological_process 19390
    metabolic process 11736
      cellular metabolic process 10656
        organic acid metabolic process 1008
          oxoacid metabolic process 976
            carboxylic acid metabolic process 957
              cellular amino acid metabolic process 272
                alpha-amino acid metabolic process 200
                  tyrosine metabolic process 15
                    D-tyrosine metabolic process + 0
                    dopamine biosynthetic process from tyrosine 1
                    melanin biosynthetic process from tyrosine 1
                    tyrosine biosynthetic process + 3
                    tyrosine catabolic process + 5
                    ubiquinone biosynthetic process from tyrosine 0
paths to the root