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ONTOLOGY REPORT - ANNOTATIONS

Term:tyrosine metabolic process
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Accession:GO:0006570 term browser browse the term
Definition:The chemical reactions and pathways involving tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid.
Synonyms:exact_synonym: tyrosine metabolism
 xref: UM-BBD_pathwayID:tyr;   Wikipedia:Tyrosine


show annotations for term's descendants           Sort by:
tyrosine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856102 (PMID:4147174) RGD PMID:4147174 NCBI chr  X:75,159,635...75,267,094
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Hgd homogentisate 1, 2-dioxygenase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr11:63,086,750...63,138,325
Ensembl chr11:63,086,752...63,138,323 		JBrowse link
G Iyd iodotyrosine deiodinase involved_in ISO
IEA
IBA
ISS 		(PMID:25395621)
GO_REF:0000107
(PMID:19777994)
GO_REF:0000033
(PMID:25395621), (PMID:28157283)
GO_REF:0000024 		RGD
Ensembl
GO_Central
UniProt		 PMID:19777994 PMID:25395621 PMID:28157283 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319 		JBrowse link
G Thap4 THAP domain containing 4 involved_in ISO
IEA
ISS 		(PMID:30524950)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:30524950 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:94,242,581...94,282,312
Ensembl chr 9:94,242,581...94,282,306 		JBrowse link
G Tmem25 transmembrane protein 25 acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 8:45,107,116...45,112,657
Ensembl chr 8:45,107,121...45,116,389 		JBrowse link
G Ttc36 tetratricopeptide repeat domain 36 acts_upstream_of_or_within
involved_in 		ISO
IEA
IBA 		MGI:5588394 (PMID:31537781)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:31537781 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:45,112,737...45,116,345 JBrowse link
dopamine biosynthetic process from tyrosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Th tyrosine hydroxylase acts_upstream_of_or_within
involved_in 		IDA
ISO
IBA
IMP 		MGI:1860450 (PMID:7592982), (PMID:7715703), (PMID:9520487)
GO_REF:0000033
PMID:11943812 		RGD
GO_Central		 PMID:7592982 PMID:7715703 PMID:9520487 PMID:2427363 PMID:20025246 More... GO_REF:0000033, RGD:1580046, RGD:4139888, RGD:5129111, RGD:5130972 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
melanin biosynthetic process from tyrosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dct dopachrome tautomerase involved_in ISO
IEA
IBA 		(PMID:2169885), (PMID:33100333)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:2169885 PMID:33100333 GO_REF:0000033 GO_REF:0000107 NCBI chr15:101,469,159...101,508,029
Ensembl chr15:95,062,003...95,100,836 		JBrowse link
G Oca2 OCA2 melanosomal transmembrane protein involved_in ISO
IEA 		(PMID:25513726), (PMID:32966160)
GO_REF:0000107 		RGD
Ensembl		 PMID:25513726 PMID:32966160 GO_REF:0000107 NCBI chr 1:116,252,026...116,581,838
Ensembl chr 1:107,116,278...107,446,074 		JBrowse link
G Slc45a2 solute carrier family 45, member 2 involved_in ISO
IEA 		(PMID:32966160)
GO_REF:0000107
(PMID:35469906) 		RGD
Ensembl		 PMID:32966160 PMID:35469906 GO_REF:0000107 NCBI chr 2:61,690,828...61,723,437
Ensembl chr 2:59,963,706...59,996,317 		JBrowse link
tyrosine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pah phenylalanine hydroxylase involved_in IDA
IBA 		GO_REF:0000033 GO_Central
RGD		 PMID:16953590 GO_REF:0000033, RGD:1601531 NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130 		JBrowse link
tyrosine biosynthetic process, by oxidation of phenylalanine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pah phenylalanine hydroxylase involved_in IDA
IEA 		GO_REF:0000108 GOC
RGD		 PMID:10839989 GO_REF:0000108, RGD:1601535 NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130 		JBrowse link
G Pcbd1 pterin-4 alpha-carbinolamine dehydratase 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr20:29,573,362...29,587,181
Ensembl chr20:28,953,864...29,044,292
Ensembl chr20:28,953,864...29,044,292 		JBrowse link
G Pcbd2 pterin-4 alpha-carbinolamine dehydratase 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr17:8,850,349...8,902,420
Ensembl chr17:8,845,084...8,910,539 		JBrowse link
G Txndc15 thioredoxin domain containing 15 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr17:8,903,248...8,915,714
Ensembl chr17:8,845,084...8,910,539
Ensembl chr 7:8,845,084...8,910,539 		JBrowse link
tyrosine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fah fumarylacetoacetate hydrolase involved_in IEA
IBA 		GO_REF:0000104
GO_REF:0000043
GO_REF:0000033 		UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000043 GO_REF:0000104 NCBI chr 1:147,957,931...147,980,708
Ensembl chr 1:138,548,834...138,571,505 		JBrowse link
G Gstz1 glutathione S-transferase zeta 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 6:112,525,576...112,536,228
Ensembl chr 6:106,794,074...106,805,284 		JBrowse link
G Hpd 4-hydroxyphenylpyruvate dioxygenase involved_in
acts_upstream_of_or_within 		TAS
IEA
IBA
ISO
IDA 		GO_REF:0000043
GO_REF:0000033
(PMID:31537781)
PMID:8814303 		UniProt
GO_Central
RGD		 PMID:31537781 PMID:12867153 PMID:8814303 GO_REF:0000033 GO_REF:0000043, RGD:632936, RGD:8554707 NCBI chr12:33,381,397...33,392,750
Ensembl chr12:33,381,231...33,392,766 		JBrowse link
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:17356132) RGD PMID:17356132 NCBI chr 1:104,435,540...104,461,049
Ensembl chr 1:95,295,601...95,324,562 		JBrowse link
G Tat tyrosine aminotransferase involved_in ISO
IEA
IBA
ISS 		(PMID:7999802)
GO_REF:0000107
GO_REF:0000043
(PMID:21153519)
GO_REF:0000033
GO_REF:0000024 		RGD
Ensembl
UniProt
GO_Central		 PMID:7999802 PMID:21153519 GO_REF:0000024 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        primary metabolic process 10727
          amino acid metabolic process 305
            aromatic amino acid metabolic process 46
              tyrosine metabolic process 19
                dopamine biosynthetic process from tyrosine 1
                melanin biosynthetic process from tyrosine 3
                tyrosine biosynthetic process + 4
                tyrosine catabolic process + 5
Path 2
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        small molecule metabolic process 1944
          organic acid metabolic process 1062
            oxoacid metabolic process 1040
              carboxylic acid metabolic process 1025
                alpha-amino acid metabolic process 224
                  L-amino acid metabolic process 189
                    erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process 33
                      tyrosine metabolic process 19
                        dopamine biosynthetic process from tyrosine 1
                        melanin biosynthetic process from tyrosine 3
                        tyrosine biosynthetic process + 4
                        tyrosine catabolic process + 5
paths to the root