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ONTOLOGY REPORT - ANNOTATIONS


Term:tryptophan catabolic process
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Accession:GO:0006569 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.
Synonyms:exact_synonym: tryptophan breakdown;   tryptophan catabolism;   tryptophan degradation
 narrow_synonym: tryptophan catabolic process, using tryptophanase;   tryptophan catabolism, using tryptophanase



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tryptophan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acmsd aminocarboxymuconate semialdehyde decarboxylase IDA RGD PMID:11802786 RGD:70243 NCBI chr13:39,200,486...39,244,337
Ensembl chr13:39,200,314...39,245,209
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877
JBrowse link
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:17356132), (PMID:25767141) RGD PMID:17356132 PMID:25767141 NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562
JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881
JBrowse link
G Kynu kynureninase involved_in ISO (PMID:17334708) RGD PMID:17334708 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
JBrowse link
tryptophan catabolic process to acetyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kynu kynureninase IDA RGD PMID:7236232 RGD:2303721 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:7236232 PMID:21873635 RGD:2303721, RGD:13792537 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511
JBrowse link
tryptophan catabolic process to indole-3-acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:32818467), (PMID:32866000) RGD PMID:32818467 PMID:32866000 NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562
JBrowse link
tryptophan catabolic process to kynurenine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
PMID:21873635
(MGI:3587527|PMID:15866519)
GO_REF:0000041
RGD
UniProt
PMID:15866519 PMID:21873635 GO_REF:0000041 MGI:3587527, RGD:13792537 NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 involved_in
acts_upstream_of_or_within
IDA
IEA
ISO
IBA
GO_REF:0000002
(MGI:2151782|PMID:2419335), (MGI:2156954|PMID:11751753)
PMID:21873635
InterPro
RGD
PMID:2419335 PMID:11751753 PMID:10719243 PMID:21873635 PMID:11513477 GO_REF:0000002 MGI:2151782 MGI:2156954, RGD:2290190, RGD:13792537, RGD:2290543 NCBI chr16:67,430,684...67,442,459
Ensembl chr16:67,430,578...67,442,730
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
PMID:21873635
(MGI:3712725|PMID:17499941), (MGI:3719924|PMID:17671174)
(PMID:17671174)
GO_REF:0000041
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:17499941 PMID:17671174 PMID:21873635 GO_REF:0000041 GO_REF:0000107 MGI:3712725 MGI:3719924, RGD:13792537 NCBI chr16:67,459,158...67,498,052
Ensembl chr16:67,459,190...67,496,324
JBrowse link
G Kynu kynureninase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:27762317)
GO_REF:0000041
UniProt
RGD
PMID:27762317 GO_REF:0000024 GO_REF:0000041 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      primary metabolic process 10535
        cellular amino acid metabolic process 277
          cellular amino acid catabolic process 107
            tryptophan catabolic process 9
              tryptophan catabolic process to acetyl-CoA 2
              tryptophan catabolic process to catechol 0
              tryptophan catabolic process to indole-3-acetate 1
              tryptophan catabolic process to kynurenine 5
Path 2
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      nitrogen compound metabolic process 9994
        organonitrogen compound metabolic process 6852
          amine metabolic process 126
            cellular amine metabolic process 118
              cellular biogenic amine metabolic process 105
                indolalkylamine metabolic process 12
                  tryptophan metabolic process 12
                    tryptophan catabolic process 9
                      tryptophan catabolic process to acetyl-CoA 2
                      tryptophan catabolic process to catechol 0
                      tryptophan catabolic process to indole-3-acetate 1
                      tryptophan catabolic process to kynurenine 5
paths to the root