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ONTOLOGY REPORT - ANNOTATIONS


Term:tryptophan metabolic process
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Accession:GO:0006568 term browser browse the term
Definition:The chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.
Synonyms:exact_synonym: tryptophan metabolism
 xref: Wikipedia:Tryptophan


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tryptophan metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO (MGI:53851|PMID:4147174) MGI PMID:4147174 MGI:53851 NCBI chrNW_004936683:2,874,022...2,936,214
Ensembl chrNW_004936683:2,874,042...2,935,040
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase ISO RGD PMID:3400092 PMID:3899109 PMID:10719243 RGD:2290190 RGD:2290313 RGD:2291804 NCBI chrNW_004936576:2,537,702...2,555,790
Ensembl chrNW_004936576:2,537,702...2,555,785
JBrowse link
'de novo' NAD biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase involved_in IEA UniProt GO_REF:0000104 NCBI chrNW_004936594:2,794,927...2,805,689
Ensembl chrNW_004936594:2,794,894...2,808,100
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in IEA UniProt
TreeGrafter
GO_REF:0000104 GO_REF:0000118 NCBI chrNW_004936508:8,971,516...8,987,235
Ensembl chrNW_004936508:8,971,477...8,986,404
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936843:658,058...672,662
Ensembl chrNW_004936843:657,979...672,700
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936843:595,237...649,390
Ensembl chrNW_004936843:594,968...649,390
JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in IEA UniProt GO_REF:0000104 NCBI chrNW_004936526:8,877,085...8,928,280
Ensembl chrNW_004936526:8,877,434...8,919,548
JBrowse link
G Kynu kynureninase involved_in IEA UniProt GO_REF:0000104 NCBI chrNW_004936469:33,632,885...33,805,158
Ensembl chrNW_004936469:33,632,892...33,734,433
JBrowse link
serotonin biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101961588 cytochrome P450 2D17 ISO RGD PMID:23098818 RGD:11353778 NCBI chrNW_004936718:153,340...157,966 JBrowse link
tryptophan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acmsd aminocarboxymuconate semialdehyde decarboxylase ISO RGD PMID:11802786 RGD:70243 NCBI chrNW_004936469:40,858,338...40,904,807
Ensembl chrNW_004936469:40,858,338...40,904,807
JBrowse link
G Afmid arylformamidase involved_in IEA UniProt GO_REF:0000043 GO_REF:0000104 NCBI chrNW_004936594:2,794,927...2,805,689
Ensembl chrNW_004936594:2,794,894...2,808,100
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in IEA UniProt GO_REF:0000104 NCBI chrNW_004936508:8,971,516...8,987,235
Ensembl chrNW_004936508:8,971,477...8,986,404
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 involved_in IEA UniProt GO_REF:0000117 NCBI chrNW_004936843:658,058...672,662
Ensembl chrNW_004936843:657,979...672,700
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 involved_in IEA UniProt GO_REF:0000117 NCBI chrNW_004936843:595,237...649,390
Ensembl chrNW_004936843:594,968...649,390
JBrowse link
G Il4i1 interleukin 4 induced 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936664:3,674,612...3,715,036
Ensembl chrNW_004936664:3,675,805...3,686,262
JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in IEA UniProt
InterPro
GO_REF:0000002 GO_REF:0000104 NCBI chrNW_004936526:8,877,085...8,928,280
Ensembl chrNW_004936526:8,877,434...8,919,548
JBrowse link
G Kynu kynureninase involved_in IEA Ensembl
UniProt
InterPro
GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 NCBI chrNW_004936469:33,632,885...33,805,158
Ensembl chrNW_004936469:33,632,892...33,734,433
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase involved_in IEA UniProt GO_REF:0000043 GO_REF:0000104 GO_REF:0000117 NCBI chrNW_004936576:2,537,702...2,555,790
Ensembl chrNW_004936576:2,537,702...2,555,785
JBrowse link
tryptophan catabolic process to acetyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kynu kynureninase ISO RGD PMID:7236232 RGD:2303721 NCBI chrNW_004936469:33,632,885...33,805,158
Ensembl chrNW_004936469:33,632,892...33,734,433
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase involved_in ISO
IEA
RGD
TreeGrafter
PMID:7236232 GO_REF:0000118 RGD:2303721 NCBI chrNW_004936576:2,537,702...2,555,790
Ensembl chrNW_004936576:2,537,702...2,555,785
JBrowse link
tryptophan catabolic process to indole-3-acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il4i1 interleukin 4 induced 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936664:3,674,612...3,715,036
Ensembl chrNW_004936664:3,675,805...3,686,262
JBrowse link
tryptophan catabolic process to kynurenine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afmid arylformamidase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3587527|PMID:15866519) MGI
InterPro
UniProt
PMID:15866519 GO_REF:0000002 GO_REF:0000041 MGI:3587527 NCBI chrNW_004936594:2,794,927...2,805,689
Ensembl chrNW_004936594:2,794,894...2,808,100
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 involved_in
acts_upstream_of_or_within
ISO
IEA
(MGI:2151782|PMID:2419335), (MGI:2156954|PMID:11751753) RGD
TreeGrafter
InterPro
Ensembl
MGI
PMID:2419335 PMID:10719243 PMID:11513477 PMID:11751753 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 MGI:2151782 MGI:2156954 RGD:2290190 RGD:2290543 NCBI chrNW_004936843:658,058...672,662
Ensembl chrNW_004936843:657,979...672,700
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3712725|PMID:17499941)
(MGI:3719924|PMID:17671174)
MGI
TreeGrafter
InterPro
Ensembl
PMID:17499941 PMID:17671174 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 MGI:3712725 MGI:3719924 NCBI chrNW_004936843:595,237...649,390
Ensembl chrNW_004936843:594,968...649,390
JBrowse link
G Kynu kynureninase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936469:33,632,885...33,805,158
Ensembl chrNW_004936469:33,632,892...33,734,433
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase involved_in IEA Ensembl
UniProt
InterPro
GO_REF:0000002 GO_REF:0000041 GO_REF:0000107 NCBI chrNW_004936576:2,537,702...2,555,790
Ensembl chrNW_004936576:2,537,702...2,555,785
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15868
    cellular process 14991
      cellular metabolic process 8295
        cellular aromatic compound metabolic process 4873
          aromatic amino acid metabolic process 35
            tryptophan metabolic process 11
              'de novo' NAD biosynthetic process from tryptophan + 6
              indoleacetic acid biosynthetic process via tryptophan + 0
              nicotinate nucleotide biosynthetic process from tryptophan 0
              positive regulation of tryptophan metabolic process + 0
              psilocybin biosynthetic process 0
              regulation of tryptophan metabolic process + 0
              serotonin biosynthetic process from tryptophan 1
              tryptophan biosynthetic process 0
              tryptophan catabolic process + 9
Path 2
Term Annotations click to browse term
  biological_process 15868
    metabolic process 9524
      organic substance metabolic process 9089
        organic acid metabolic process 879
          oxoacid metabolic process 862
            carboxylic acid metabolic process 848
              alpha-amino acid metabolic process 208
                tryptophan metabolic process 11
                  'de novo' NAD biosynthetic process from tryptophan + 6
                  indoleacetic acid biosynthetic process via tryptophan + 0
                  nicotinate nucleotide biosynthetic process from tryptophan 0
                  positive regulation of tryptophan metabolic process + 0
                  psilocybin biosynthetic process 0
                  regulation of tryptophan metabolic process + 0
                  serotonin biosynthetic process from tryptophan 1
                  tryptophan biosynthetic process 0
                  tryptophan catabolic process + 9
paths to the root