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ONTOLOGY REPORT - ANNOTATIONS


Term:proline catabolic process
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Accession:GO:0006562 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.
Synonyms:exact_synonym: proline breakdown;   proline catabolism;   proline degradation



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proline catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DAO D-amino acid oxidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:41,931,549...41,950,628
Ensembl chr14:41,929,215...41,950,633
JBrowse link
G PRODH2 proline dehydrogenase 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 6:45,213,712...45,240,437 JBrowse link
proline catabolic process to glutamate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH4A1 aldehyde dehydrogenase 4 family member A1 involved_in IEA UniProt GO_REF:0000041 NCBI chr 6:77,373,999...77,404,015
Ensembl chr 6:77,373,999...77,393,651
JBrowse link
G LOC110256626 proline dehydrogenase 1, mitochondrial involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:51,624,919...51,644,467 JBrowse link
G PRODH2 proline dehydrogenase 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:45,213,712...45,240,437 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16582
    metabolic process 10425
      primary metabolic process 9274
        cellular amino acid metabolic process 267
          cellular amino acid catabolic process 92
            proline catabolic process 4
              proline catabolic process to 2-oxoglutarate 0
              proline catabolic process to glutamate + 3
Path 2
Term Annotations click to browse term
  biological_process 16582
    metabolic process 10425
      cellular metabolic process 9472
        organic acid metabolic process 885
          oxoacid metabolic process 858
            carboxylic acid metabolic process 840
              cellular amino acid metabolic process 267
                alpha-amino acid metabolic process 194
                  glutamine family amino acid metabolic process 75
                    glutamine family amino acid catabolic process 22
                      proline catabolic process 4
                        proline catabolic process to 2-oxoglutarate 0
                        proline catabolic process to glutamate + 3
paths to the root