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ONTOLOGY REPORT - ANNOTATIONS


Term:proline biosynthetic process
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Accession:GO:0006561 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.
Synonyms:exact_synonym: proline anabolism;   proline biosynthesis;   proline formation;   proline synthesis
 xref: MetaCyc:PROSYN-PWY;   MetaCyc:PWY-3341



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proline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 involved_in ISO (PMID:11092761), (PMID:26297558) RGD PMID:11092761 PMID:26297558 NCBI chr 1:239,375,657...239,407,967
Ensembl chr 1:239,375,669...239,407,890
JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 involved_in ISO (PMID:16730026) RGD PMID:16730026 NCBI chr10:105,917,732...105,922,658
Ensembl chr10:105,917,680...105,922,549
JBrowse link
G Pycr2 pyrroline-5-carboxylate reductase 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:23024808)
UniProt
RGD
PMID:23024808 GO_REF:0000024 NCBI chr13:92,626,462...92,630,256
Ensembl chr13:92,626,471...92,634,184
JBrowse link
L-proline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:239,375,657...239,407,967
Ensembl chr 1:239,375,669...239,407,890
JBrowse link
G Noxred1 NADP-dependent oxidoreductase domain containing 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:106,862,350...106,888,113
Ensembl chr 6:106,862,343...106,884,712
JBrowse link
G Oat ornithine aminotransferase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 involved_in IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr10:105,917,732...105,922,658
Ensembl chr10:105,917,680...105,922,549
JBrowse link
G Pycr2 pyrroline-5-carboxylate reductase 2 involved_in IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr13:92,626,462...92,630,256
Ensembl chr13:92,626,471...92,634,184
JBrowse link
G Pycr3 pyrroline-5-carboxylate reductase 3 involved_in IBA
ISS
ISO
IEA
PMID:21873635
GO_REF:0000024
(PMID:23024808)
GO_REF:0000041
UniProt
RGD
PMID:23024808 PMID:21873635 GO_REF:0000024 GO_REF:0000041, RGD:13792537 NCBI chr 7:107,603,543...107,608,831 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19541
    metabolic process 11844
      primary metabolic process 10558
        cellular amino acid metabolic process 277
          cellular amino acid biosynthetic process 72
            alpha-amino acid biosynthetic process 66
              glutamine family amino acid biosynthetic process 17
                proline biosynthetic process 6
                  L-proline biosynthetic process 6
                  negative regulation of proline biosynthetic process 0
                  proline salvage 0
                  regulation of proline biosynthetic process + 0
Path 2
Term Annotations click to browse term
  biological_process 19541
    metabolic process 11844
      cellular metabolic process 10738
        organic acid metabolic process 1016
          oxoacid metabolic process 984
            carboxylic acid metabolic process 963
              cellular amino acid metabolic process 277
                alpha-amino acid metabolic process 199
                  glutamine family amino acid metabolic process 74
                    proline metabolic process 12
                      proline biosynthetic process 6
                        L-proline biosynthetic process 6
                        negative regulation of proline biosynthetic process 0
                        proline salvage 0
                        regulation of proline biosynthetic process + 0
paths to the root