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ONTOLOGY REPORT - ANNOTATIONS


Term:proline metabolic process
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Accession:GO:0006560 term browser browse the term
Definition:The chemical reactions and pathways involving proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.
Synonyms:exact_synonym: proline metabolism


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L-proline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pycr3 pyrroline-5-carboxylate reductase 3 involved_in ISO (PMID:23024808) UniProt PMID:23024808 NCBI chrNW_004936470:8,527,896...8,531,788 JBrowse link
proline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101975532 delta-1-pyrroline-5-carboxylate synthase involved_in ISO (PMID:11092761), (PMID:26297558) UniProt PMID:11092761 PMID:26297558 NCBI chrNW_004936636:3,779,259...3,800,846 JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 involved_in ISO (PMID:16730026) UniProt PMID:16730026 NCBI chrNW_004936594:5,439,911...5,443,535 JBrowse link
G Pycr2 pyrroline-5-carboxylate reductase 2 involved_in ISO (PMID:23024808) UniProt PMID:23024808 NCBI chrNW_004936526:2,721,579...2,726,699 JBrowse link
proline catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dao D-amino acid oxidase involved_in ISO (PMID:16616139) UniProt PMID:16616139 NCBI chrNW_004936769:744,862...758,086 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12174
    metabolic process 7651
      primary metabolic process 6750
        cellular amino acid metabolic process 186
          alpha-amino acid metabolic process 137
            glutamine family amino acid metabolic process 50
              proline metabolic process 5
                arginine catabolic process to proline + 0
                negative regulation of proline metabolic process + 0
                nopaline catabolic process to proline 0
                octopine catabolic process to proline 0
                ornithine catabolic process via proline 0
                positive regulation of proline metabolic process + 0
                proline biosynthetic process + 4
                proline catabolic process + 1
                regulation of proline metabolic process + 0
Path 2
Term Annotations click to browse term
  biological_process 12174
    metabolic process 7651
      cellular metabolic process 7016
        organic acid metabolic process 652
          oxoacid metabolic process 634
            carboxylic acid metabolic process 626
              cellular amino acid metabolic process 186
                alpha-amino acid metabolic process 137
                  glutamine family amino acid metabolic process 50
                    proline metabolic process 5
                      arginine catabolic process to proline + 0
                      negative regulation of proline metabolic process + 0
                      nopaline catabolic process to proline 0
                      octopine catabolic process to proline 0
                      ornithine catabolic process via proline 0
                      positive regulation of proline metabolic process + 0
                      proline biosynthetic process + 4
                      proline catabolic process + 1
                      regulation of proline metabolic process + 0
paths to the root